Investigations into the HPLC retention behavior of simvastatin and structurally related compounds

Journal of Liquid Chromatography and Related Technologies

Volumn 28, Issue 17, 2005, Pages 2719-2735

  Trone, Mark D ^a,b   McMicken, Naomi K ^a   Thomas, Scott M ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

^b GLAXOSMITHKLINE   (United States)

Author keywords

HPLC; Related compounds; Retention behavior; Simvastatin

Indexed keywords

CARBOXYLIC ACIDS; COMPOSITION; ENTHALPY; ENTROPY; ESTERS; THERMODYNAMICS;

HPLC; RELATED COMPOUNDS; RETENTION BEHAVIOR; SIMVASTATIN;

HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;

ACID; BETA,DELTA DIHYDROXY ACID; ESTER DERIVATIVE; LACTONE; SIMVASTATIN; UNCLASSIFIED DRUG;

ACIDITY; ADSORPTION; ARTICLE; DRUG STRUCTURE; ELUTION; ENTHALPY; ENTROPY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HIGH TEMPERATURE; LOW TEMPERATURE; PH; TEMPERATURE DEPENDENCE;

EID: 27544438599     PISSN: 10826076     EISSN: 1520572X     Source Type: Journal    
DOI: 10.1080/10826070500224807     Document Type: Article

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