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Volumn 391, Issue 2, 2005, Pages 325-333

Slx4 becomes phosphorylated after DNA damage in a Mec1/Tel1-dependent manner and is required for repair of DNA alkylation damage

Author keywords

Ataxia telangiectasia mutated (ATM); ATM and Rad3 related (ATR); DNA damage; Mec1; Sgs1; Slx

Indexed keywords

ALKYLATION; CELLS; ENZYMES; GENES; MUTAGENESIS; TUMORS;

EID: 27444444448     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/BJ20050768     Document Type: Article
Times cited : (44)

References (43)
  • 1
    • 0036948433 scopus 로고    scopus 로고
    • Toward maintaining the genome: DNA damage and replication checkpoints
    • Nyberg, K. A., Michelson, R. J., Putnam, C. W. and Weinert, T. A. (2002) Toward maintaining the genome: DNA damage and replication checkpoints. Annu. Rev. Genet. 36, 617-656
    • (2002) Annu. Rev. Genet. , vol.36 , pp. 617-656
    • Nyberg, K.A.1    Michelson, R.J.2    Putnam, C.W.3    Weinert, T.A.4
  • 2
    • 0037178748 scopus 로고    scopus 로고
    • Interfaces between the detection, signaling, and repair of DNA damage
    • Rouse, J. and Jackson, S. P. (2002) Interfaces between the detection, signaling, and repair of DNA damage. Science 297, 547-551
    • (2002) Science , vol.297 , pp. 547-551
    • Rouse, J.1    Jackson, S.P.2
  • 3
    • 0037365789 scopus 로고    scopus 로고
    • ATM and related protein kinases: Safeguarding genome integrity
    • Shiloh, Y. (2003) ATM and related protein kinases: safeguarding genome integrity. Nat. Rev. Cancer 3, 155-168
    • (2003) Nat. Rev. Cancer , vol.3 , pp. 155-168
    • Shiloh, Y.1
  • 5
    • 3242882820 scopus 로고    scopus 로고
    • Pl 3-kinase related kinases: 'Big' players in stress-induced signaling pathways
    • Abraham, R. T. (2004) Pl 3-kinase related kinases: 'big' players in stress-induced signaling pathways. DNA Repair 3, 883-887
    • (2004) DNA Repair , vol.3 , pp. 883-887
    • Abraham, R.T.1
  • 6
    • 0035449355 scopus 로고    scopus 로고
    • Cell cycle checkpoint signaling through the ATM and ATR kinases
    • Abraham, R. T. (2001) Cell cycle checkpoint signaling through the ATM and ATR kinases. Genes Dev. 15, 2177-2196
    • (2001) Genes Dev. , vol.15 , pp. 2177-2196
    • Abraham, R.T.1
  • 7
    • 0037027880 scopus 로고    scopus 로고
    • DNA structure dependent checkpoints as regulators of DNA repair
    • Carr, A. M. (2002) DNA structure dependent checkpoints as regulators of DNA repair. DNA Repair 1, 983-994
    • (2002) DNA Repair , vol.1 , pp. 983-994
    • Carr, A.M.1
  • 8
    • 0345276624 scopus 로고    scopus 로고
    • Regulation of alternative replication bypass pathways at stalled replication forks and its effects on genome stability: A yeast model
    • Barbour, L. and Xiao, W. (2003) Regulation of alternative replication bypass pathways at stalled replication forks and its effects on genome stability: a yeast model. Mutat. Res. 532, 137-155
    • (2003) Mutat. Res. , vol.532 , pp. 137-155
    • Barbour, L.1    Xiao, W.2
  • 9
    • 0037168658 scopus 로고    scopus 로고
    • Alternate pathways involving Sgs1/Top3, Mus81/Mms4, and Srs2 prevent formation of toxic recombination intermediates from single-stranded gaps created by DNA replication
    • Fabre, F., Chan, A., Heyer, W. D. and Gangloff, S. (2002) Alternate pathways involving Sgs1/Top3, Mus81/Mms4, and Srs2 prevent formation of toxic recombination intermediates from single-stranded gaps created by DNA replication. Proc. Natl. Acad. Sci. U.S.A. 99, 16887-16892
    • (2002) Proc. Natl. Acad. Sci. U.S.A. , vol.99 , pp. 16887-16892
    • Fabre, F.1    Chan, A.2    Heyer, W.D.3    Gangloff, S.4
  • 10
    • 0037364415 scopus 로고    scopus 로고
    • RecQ helicases: Caretakers of the genome
    • Hickson, I. D. (2003) RecQ helicases: caretakers of the genome. Nat. Rev. Cancer 3, 169-178
    • (2003) Nat. Rev. Cancer , vol.3 , pp. 169-178
    • Hickson, I.D.1
  • 12
    • 10644267656 scopus 로고    scopus 로고
    • Understanding the roles of RecQ helicases in the maintenance of genome integrity and suppression of tumorigenesis
    • Mankouri, H. W. and Hickson, I.D. (2004) Understanding the roles of RecQ helicases in the maintenance of genome integrity and suppression of tumorigenesis. Biochem. Soc. Trans. 32, 957-958
    • (2004) Biochem. Soc. Trans. , vol.32 , pp. 957-958
    • Mankouri, H.W.1    Hickson, I.D.2
  • 13
    • 0042466524 scopus 로고    scopus 로고
    • DNA polymerase stabilization at stalled replication forks requires Med and the RecQ helicase Sgs1
    • Cobb, J. A., Bjergbaek, L., Shimada, K., Frei, C. and Gasser, S. M. (2003) DNA polymerase stabilization at stalled replication forks requires Med and the RecQ helicase Sgs1. EMBO J. 22, 4325-4336
    • (2003) EMBO J. , vol.22 , pp. 4325-4336
    • Cobb, J.A.1    Bjergbaek, L.2    Shimada, K.3    Frei, C.4    Gasser, S.M.5
  • 14
    • 10044259570 scopus 로고    scopus 로고
    • The ability of Sgs1 to interact with DNA topoisomerase III is essential for damage-induced recombination
    • Ui, A., Seki, M., Ogiwara, H., Onodera, R., Fukushige, S., Onoda, F. and Enomoto, T. (2005) The ability of Sgs1 to interact with DNA topoisomerase III is essential for damage-induced recombination. DNA Repair 4, 191-201
    • (2005) DNA Repair , vol.4 , pp. 191-201
    • Ui, A.1    Seki, M.2    Ogiwara, H.3    Onodera, R.4    Fukushige, S.5    Onoda, F.6    Enomoto, T.7
  • 15
    • 0028033989 scopus 로고
    • The yeast type I topoisomerase Top3 interacts with Sgs1, a DNA helicase homolog: A potential eukaryotic reverse gyrase
    • Gangloff, S., McDonald, J. P., Bendixen, C., Arthur, L. and Rothstein, R. (1994) The yeast type I topoisomerase Top3 interacts with Sgs1, a DNA helicase homolog: a potential eukaryotic reverse gyrase. Mol. Cell. Biol. 14, 8391-8398
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 8391-8398
    • Gangloff, S.1    McDonald, J.P.2    Bendixen, C.3    Arthur, L.4    Rothstein, R.5
  • 16
    • 0029657781 scopus 로고    scopus 로고
    • SGS1, a homologue of the Bloom's and Werner's syndrome genes, is required for maintenance of genome stability in Saccharomyces cerevisiae
    • Watt, P. M., Hickson, I. D., Borts, R. H. and Louis, E. J. (1996) SGS1, a homologue of the Bloom's and Werner's syndrome genes, is required for maintenance of genome stability in Saccharomyces cerevisiae. Genetics 144, 935-945
    • (1996) Genetics , vol.144 , pp. 935-945
    • Watt, P.M.1    Hickson, I.D.2    Borts, R.H.3    Louis, E.J.4
  • 17
    • 0034089029 scopus 로고    scopus 로고
    • Bipartite structure of the SGS1 DNA helicase in Saccharomyces cerevisiae
    • Mullen, J. R., Kaliraman, V. and Brill, S. J. (2000) Bipartite structure of the SGS1 DNA helicase in Saccharomyces cerevisiae. Genetics 154, 1101-1114
    • (2000) Genetics , vol.154 , pp. 1101-1114
    • Mullen, J.R.1    Kaliraman, V.2    Brill, S.J.3
  • 18
    • 0032555220 scopus 로고    scopus 로고
    • Bloom's and Werner's syndrome genes suppress hyperrecombination in yeast sgs1 mutant: Implication for genomic instability in human diseases
    • Yamagata, K., Kato, J., Shimamoto, A., Goto, M., Furuichi, Y. and Ikeda, H. (1998) Bloom's and Werner's syndrome genes suppress hyperrecombination in yeast sgs1 mutant: implication for genomic instability in human diseases. Proc. Natl. Acad. Sci. U.S.A. 95, 8733-8738
    • (1998) Proc. Natl. Acad. Sci. U.S.A. , vol.95 , pp. 8733-8738
    • Yamagata, K.1    Kato, J.2    Shimamoto, A.3    Goto, M.4    Furuichi, Y.5    Ikeda, H.6
  • 19
    • 0033957793 scopus 로고    scopus 로고
    • The yeast Sgs1p helicase acts upstream of Rad53p in the DNA replication checkpoint and colocalizes with Rad53p in S-phase-specific foci
    • Frei, C. and Gasser, S. M. (2000) The yeast Sgs1p helicase acts upstream of Rad53p in the DNA replication checkpoint and colocalizes with Rad53p in S-phase-specific foci. Genes Dev. 14, 81-96
    • (2000) Genes Dev. , vol.14 , pp. 81-96
    • Frei, C.1    Gasser, S.M.2
  • 21
    • 1642458364 scopus 로고    scopus 로고
    • Phosphorylation of the Bloom's syndrome helicase and its role in recovery from S-phase arrest
    • Davies, S. L., North, P. S., Dart, A., Lakin, N. D. and Hickson, I. D. (2004) Phosphorylation of the Bloom's syndrome helicase and its role in recovery from S-phase arrest. Mol. Cell. Biol. 24, 1279-1291
    • (2004) Mol. Cell. Biol. , vol.24 , pp. 1279-1291
    • Davies, S.L.1    North, P.S.2    Dart, A.3    Lakin, N.D.4    Hickson, I.D.5
  • 23
    • 0034119866 scopus 로고    scopus 로고
    • Homologous recombination is responsible for cell death in the absence of the Sgs1 and Srs2 helicases
    • Gangloff, S., Soustelle, C. and Fabre, F. (2000) Homologous recombination is responsible for cell death in the absence of the Sgs1 and Srs2 helicases. Nat. Genet. 25, 192-194
    • (2000) Nat. Genet. , vol.25 , pp. 192-194
    • Gangloff, S.1    Soustelle, C.2    Fabre, F.3
  • 24
    • 0035148955 scopus 로고    scopus 로고
    • Requirement for three novel protein complexes in the absence of the Sgs1 DNA helicase in Saccharomyces cerevisiae
    • Mullen, J. R., Kaliraman, V., Ibrahim, S. S. and Brill, S. J. (2001) Requirement for three novel protein complexes in the absence of the Sgs1 DNA helicase in Saccharomyces cerevisiae. Genetics 157, 103-118
    • (2001) Genetics , vol.157 , pp. 103-118
    • Mullen, J.R.1    Kaliraman, V.2    Ibrahim, S.S.3    Brill, S.J.4
  • 26
    • 0037031837 scopus 로고    scopus 로고
    • Mus81-Eme1 and Rqh1 involvement in processing stalled and collapsed replication forks
    • Doe, C. L., Ahn, J. S., Dixon, J. and Whitby, M. C. (2002) Mus81-Eme1 and Rqh1 involvement in processing stalled and collapsed replication forks. J. Biol. Chem. 277, 32753-32759
    • (2002) J. Biol. Chem. , vol.277 , pp. 32753-32759
    • Doe, C.L.1    Ahn, J.S.2    Dixon, J.3    Whitby, M.C.4
  • 27
    • 0037470059 scopus 로고    scopus 로고
    • Cleavage of model replication forks by fission yeast Mus81-Eme1 and budding yeast Mus81-Mms4
    • Whitby, M. C., Osman, F. and Dixon, J. (2003) Cleavage of model replication forks by fission yeast Mus81-Eme1 and budding yeast Mus81-Mms4. J. Biol. Chem. 278, 6928-6935
    • (2003) J. Biol. Chem. , vol.278 , pp. 6928-6935
    • Whitby, M.C.1    Osman, F.2    Dixon, J.3
  • 29
    • 0038167328 scopus 로고    scopus 로고
    • Slx1-Slx4 is a second structure-specific endonuclease functionalIy redundant with Sgs1-Top3
    • Fricke, W. M. and Brill, S. J. (2003) Slx1-Slx4 is a second structure-specific endonuclease functionalIy redundant with Sgs1-Top3. Genes Dev. 17, 1768-1778
    • (2003) Genes Dev. , vol.17 , pp. 1768-1778
    • Fricke, W.M.1    Brill, S.J.2
  • 30
    • 0036939741 scopus 로고    scopus 로고
    • Role of SGS1 and SLX4 in maintaining rDNA structure in Saccharomyces cerevisiae
    • Kaliraman, V. and Brill, S. J. (2002) Role of SGS1 and SLX4 in maintaining rDNA structure in Saccharomyces cerevisiae. Curr. Genet. 41, 389-400
    • (2002) Curr. Genet. , vol.41 , pp. 389-400
    • Kaliraman, V.1    Brill, S.J.2
  • 31
    • 0347990576 scopus 로고    scopus 로고
    • Slx1-Slx4 are subunits of a structure-specific endonuclease that maintains ribosomal DNA in fission yeast
    • Coulon, S., Gaillard, P. H., Chahwan, C., McDonald, W. H., Yates, 3rd, J. R. and Russell, P. (2004) Slx1-Slx4 are subunits of a structure-specific endonuclease that maintains ribosomal DNA in fission yeast. Mol. Biol. Cell 15, 71-80
    • (2004) Mol. Biol. Cell , vol.15 , pp. 71-80
    • Coulon, S.1    Gaillard, P.H.2    Chahwan, C.3    McDonald, W.H.4    Yates III, J.R.5    Russell, P.6
  • 32
    • 0031820288 scopus 로고    scopus 로고
    • Additional modules for versatile and economical PCR-based gene deletion and modification in Saccharomyces cerevisiae
    • Longtine, M. S., McKenzie, 3rd, A., Demarini, D. J., Shah, N. G., Wach, A., Brachat, A., Philippsen, P. and Pringle, J. R. (1998) Additional modules for versatile and economical PCR-based gene deletion and modification in Saccharomyces cerevisiae. Yeast 14, 953-961
    • (1998) Yeast , vol.14 , pp. 953-961
    • Longtine, M.S.1    McKenzie III, A.2    Demarini, D.J.3    Shah, N.G.4    Wach, A.5    Brachat, A.6    Philippsen, P.7    Pringle, J.R.8
  • 33
    • 0035449349 scopus 로고    scopus 로고
    • The yeast Xrs2 complex functions in S phase checkpoint regulation
    • D'Amours, D. and Jackson, S. P. (2001) The yeast Xrs2 complex functions in S phase checkpoint regulation. Genes Dev. 15, 2238-2249
    • (2001) Genes Dev. , vol.15 , pp. 2238-2249
    • D'Amours, D.1    Jackson, S.P.2
  • 34
    • 0034329474 scopus 로고    scopus 로고
    • LCD1: An essential gene involved in checkpoint control and regulation of the MEC1 signalling pathway in Saccharomyces cerevisiae
    • Rouse, J. and Jackson, S. P. (2000) LCD1: an essential gene involved in checkpoint control and regulation of the MEC1 signalling pathway in Saccharomyces cerevisiae. EMBO J. 19, 5801-5812
    • (2000) EMBO J. , vol.19 , pp. 5801-5812
    • Rouse, J.1    Jackson, S.P.2
  • 36
    • 1842472073 scopus 로고    scopus 로고
    • Esc4p, a new target of Medp (ATR), promotes resumption of DNA synthesis after DNA damage
    • Rouse, J. (2004) Esc4p, a new target of Medp (ATR), promotes resumption of DNA synthesis after DNA damage. EMBO J. 23, 1188-1197
    • (2004) EMBO J. , vol.23 , pp. 1188-1197
    • Rouse, J.1
  • 37
    • 0025288239 scopus 로고
    • Distribution of methyl and ethyl adducts following alkylation with monofunctional alkylating agents
    • Beranek, D. T. (1990) Distribution of methyl and ethyl adducts following alkylation with monofunctional alkylating agents. Mutat. Res. 231, 11-30
    • (1990) Mutat. Res. , vol.231 , pp. 11-30
    • Beranek, D.T.1
  • 38
    • 0038730929 scopus 로고    scopus 로고
    • A central role for DNA replication forks in checkpoint activation and response
    • Tercero, J. A., Longhese, M. P. and Diffley, J. F. (2003) A central role for DNA replication forks in checkpoint activation and response. Mol. Cell 11, 1323-1336
    • (2003) Mol. Cell , vol.11 , pp. 1323-1336
    • Tercero, J.A.1    Longhese, M.P.2    Diffley, J.F.3
  • 39
    • 0037168646 scopus 로고    scopus 로고
    • A genome-wide screen for methyl methanesulfonate-sensitive mutants reveals genes reguired for S phase progression in the presence of DNA damage
    • Chang, M., Bellaoui, M., Boone, C. and Brown, G. W. (2002) A genome-wide screen for methyl methanesulfonate-sensitive mutants reveals genes reguired for S phase progression in the presence of DNA damage. Proc. Natl. Acad. Sci. U.S.A. 99, 16934-16939
    • (2002) Proc. Natl. Acad. Sci. U.S.A. , vol.99 , pp. 16934-16939
    • Chang, M.1    Bellaoui, M.2    Boone, C.3    Brown, G.W.4
  • 40
    • 0042470439 scopus 로고    scopus 로고
    • Rad53 phosphorylation site clusters are important for Rad53 regulation and signaling
    • Lee, S. J., Schwartz, M. F., Duong, J. K. and Stern, D. F. (2003) Rad53 phosphorylation site clusters are important for Rad53 regulation and signaling. Mol. Cell. Biol. 23, 6300-6314
    • (2003) Mol. Cell. Biol. , vol.23 , pp. 6300-6314
    • Lee, S.J.1    Schwartz, M.F.2    Duong, J.K.3    Stern, D.F.4
  • 41
    • 0025821897 scopus 로고
    • A group of interacting yeast DNA replication genes
    • Hennessy, K. M., Lee, A., Chen, E. and Botstein, D. (1991) A group of interacting yeast DNA replication genes. Genes Dev. 5, 958-969
    • (1991) Genes Dev. , vol.5 , pp. 958-969
    • Hennessy, K.M.1    Lee, A.2    Chen, E.3    Botstein, D.4
  • 42
    • 10344263324 scopus 로고    scopus 로고
    • Recombination proteins in yeast
    • Krogh, B. O. and Symington, L. S. (2004) Recombination proteins in yeast. Annu. Rev. Genet. 23, 233-271
    • (2004) Annu. Rev. Genet. , vol.23 , pp. 233-271
    • Krogh, B.O.1    Symington, L.S.2
  • 43
    • 0030446287 scopus 로고    scopus 로고
    • The repair of DNA methylation damage in Saccharomyces cerevisiae
    • Xiao, W., Chow, B. L. and Rathgeber, L. (1996) The repair of DNA methylation damage in Saccharomyces cerevisiae. Curr. Genet. 30, 461-468
    • (1996) Curr. Genet. , vol.30 , pp. 461-468
    • Xiao, W.1    Chow, B.L.2    Rathgeber, L.3


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