Selective inhibitors of the serine protease plasmin: Probing the S3 and S3′ subsites using a combinatorial library

Journal of Medicinal Chemistry

Volumn 48, Issue 22, 2005, Pages 6908-6917

  Xue, Fengtian ^a   Seto, Christopher T ^a  

^a BROWN UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOHEXANONE DERIVATIVE; KALLIKREIN; PLASMIN; SERINE PROTEINASE; SERINE PROTEINASE INHIBITOR; THROMBIN; TRYPSIN;

AMINO ACID SEQUENCE; ARTICLE; COMBINATORIAL LIBRARY; CONCENTRATION RESPONSE; DRUG ACTIVITY; DRUG DESIGN; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME INHIBITION; SOLID; STRUCTURE ANALYSIS;

COMBINATORIAL CHEMISTRY TECHNIQUES; CYCLOHEXANONES; PLASMIN; SERINE PROTEINASE INHIBITORS; STRUCTURE-ACTIVITY RELATIONSHIP; TRYPTOPHAN;

EID: 27444439184     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm050488k     Document Type: Article

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