메뉴 건너뛰기




Volumn 216, Issue 1, 2005, Pages 24-31

Modulation of cytochrome P450 and phase II enzymes by protocatechuic acid in mouse liver and kidney

Author keywords

Cytochrome P450; Mouse liver and kidney microsomes; Phase II enzymes; Protocatechuic acid

Indexed keywords

4 NITROPHENOL HYDROXYLASE; ANTIOXIDANT; CYTOCHROME P450; CYTOCHROME P450 1A1; CYTOCHROME P450 1A2; CYTOCHROME P450 2E1; ETHOXYRESORUFIN DEETHYLASE; GLUCURONOSYLTRANSFERASE; GLUTATHIONE TRANSFERASE; ISOENZYME; METHOXYRESORUFIN O DEMETHYLASE; PENTOXYRESORUFIN DEALKYLASE; PROTOCATECHUIC ACID; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE (PHOSPHATE) DEHYDROGENASE (QUINONE); UNCLASSIFIED DRUG;

EID: 27444439004     PISSN: 0300483X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tox.2005.07.013     Document Type: Article
Times cited : (20)

References (48)
  • 1
    • 0031687374 scopus 로고    scopus 로고
    • Inhibition of murine hepatic cytochrome P450 activities by natural and synthetic phenolic compounds
    • W. Baer-Dubowska, H. Szaefer, and V. Krajka-Kuźniak Inhibition of murine hepatic cytochrome P450 activities by natural and synthetic phenolic compounds Xenobiotica 28 1998 735 743
    • (1998) Xenobiotica , vol.28 , pp. 735-743
    • Baer-Dubowska, W.1    Szaefer, H.2    Krajka-Kuźniak, V.3
  • 2
    • 0031308138 scopus 로고    scopus 로고
    • Induction of DT-diaphorase in cancer chemoprevention and chemotherapy
    • A. Begleiter, M.K. Leith, T.J. Curphey, and G.P. Doherty Induction of DT-diaphorase in cancer chemoprevention and chemotherapy Oncol. Res. 9 1997 371 382
    • (1997) Oncol. Res. , vol.9 , pp. 371-382
    • Begleiter, A.1    Leith, M.K.2    Curphey, T.J.3    Doherty, G.P.4
  • 3
    • 0022608501 scopus 로고
    • Induction of DT-diaphorase by anticarcinogenic sulfur compounds in mice
    • A.M. Benson, P.B. Barretto, and J.S. Stanley Induction of DT-diaphorase by anticarcinogenic sulfur compounds in mice J. Natl. Cancer Inst. 76 1986 467 473
    • (1986) J. Natl. Cancer Inst. , vol.76 , pp. 467-473
    • Benson, A.M.1    Barretto, P.B.2    Stanley, J.S.3
  • 4
    • 0022357068 scopus 로고
    • Ethoxy-, pentoxy- and benzyloxy-phenoxazones and homologues: A series of substrates to distinguish between different induced cytochromes P-450
    • M.D. Burke, S. Thompson, C.R. Elcombe, J. Halpert, T. Haaparanta, and R.T. Mayer Ethoxy-, pentoxy- and benzyloxy-phenoxazones and homologues: a series of substrates to distinguish between different induced cytochromes P-450 Biochem. Pharmacol. 34 1985 3337 3345
    • (1985) Biochem. Pharmacol. , vol.34 , pp. 3337-3345
    • Burke, M.D.1    Thompson, S.2    Elcombe, C.R.3    Halpert, J.4    Haaparanta, T.5    Mayer, R.T.6
  • 5
    • 0032543429 scopus 로고    scopus 로고
    • Mechanisms of inhibitors of mutagenesis and carcinogenesis
    • S. De Flora Mechanisms of inhibitors of mutagenesis and carcinogenesis Mutat. Res. 402 1998 151 158
    • (1998) Mutat. Res. , vol.402 , pp. 151-158
    • De Flora, S.1
  • 6
    • 0023894554 scopus 로고
    • Influence of DT-diaphorase on the mutagenicity of organic and inorganic compounds
    • S. De Flora, C. Bennicelli, A. Camoirano, D. Serra, and P. Hochstein Influence of DT-diaphorase on the mutagenicity of organic and inorganic compounds Carcinogenesis 9 1988 611 617
    • (1988) Carcinogenesis , vol.9 , pp. 611-617
    • De Flora, S.1    Bennicelli, C.2    Camoirano, A.3    Serra, D.4    Hochstein, P.5
  • 7
    • 0021232262 scopus 로고
    • Effect of toluidines on drug metabolizing enzymes in rat liver, kidney and lung
    • J. Gnojkowski, W. Baer-Dubowska, D. Klimek, and J. Chmiel Effect of toluidines on drug metabolizing enzymes in rat liver, kidney and lung Toxicology 32 1984 335 342
    • (1984) Toxicology , vol.32 , pp. 335-342
    • Gnojkowski, J.1    Baer-Dubowska, W.2    Klimek, D.3    Chmiel, J.4
  • 8
    • 0016275313 scopus 로고
    • Glutathione S-transferase. the first enzymatic steps in mercapturic acid formation
    • W.H. Habig, M.J. Pabst, and W.B. Jakoby Glutathione S-transferase. The first enzymatic steps in mercapturic acid formation J. Biol. Chem. 249 1974 7130 7139
    • (1974) J. Biol. Chem. , vol.249 , pp. 7130-7139
    • Habig, W.H.1    Pabst, M.J.2    Jakoby, W.B.3
  • 9
    • 0023492742 scopus 로고
    • Monoclonal antibody characterization of hepatic and extrahepatic cytochrome P450 activities in rats treated with phenobarbital or methylcholanthrene and fed various cholesterol diets
    • E. Hietanen, M. Ahotupa, J.C. Bereziat, S.S. Park, H.V. Gelboin, and H. Bartsch Monoclonal antibody characterization of hepatic and extrahepatic cytochrome P450 activities in rats treated with phenobarbital or methylcholanthrene and fed various cholesterol diets Biochem. Pharmacol. 36 1987 3973 3990
    • (1987) Biochem. Pharmacol. , vol.36 , pp. 3973-3990
    • Hietanen, E.1    Ahotupa, M.2    Bereziat, J.C.3    Park, S.S.4    Gelboin, H.V.5    Bartsch, H.6
  • 10
    • 0028874681 scopus 로고
    • Chemoprevention of urinary bladder carcinogenesis by the natural phenolic compound protocatechuic acid in rats
    • Y. Hirose, T. Tanaka, T. Kawamori, M. Ohnishi, H. Makita, H. Mori, K. Satoh, and A. Hara Chemoprevention of urinary bladder carcinogenesis by the natural phenolic compound protocatechuic acid in rats Carcinogenesis 16 1995 2337 2342
    • (1995) Carcinogenesis , vol.16 , pp. 2337-2342
    • Hirose, Y.1    Tanaka, T.2    Kawamori, T.3    Ohnishi, M.4    Makita, H.5    Mori, H.6    Satoh, K.7    Hara, A.8
  • 11
    • 0033749223 scopus 로고    scopus 로고
    • Characterization of potentially chemopreventive phenols in extracts of brown rice that inhibit the growth of human breast and colon cancer cells
    • E.A. Hudson, P.A. Dinh, T. Kokubun, M.S. Simmonds, and A. Gescher Characterization of potentially chemopreventive phenols in extracts of brown rice that inhibit the growth of human breast and colon cancer cells Cancer Epidemiol. Biomarkers Prev. 9 2000 1163 1170
    • (2000) Cancer Epidemiol. Biomarkers Prev. , vol.9 , pp. 1163-1170
    • Hudson, E.A.1    Dinh, P.A.2    Kokubun, T.3    Simmonds, M.S.4    Gescher, A.5
  • 12
    • 1542440268 scopus 로고    scopus 로고
    • Effect of methanol extract of Zanthoxylum piperitum leaves and of its compound, protocatechuic acid, on hepatic drug metabolizing enzymes and lipid peroxidation in rats
    • J.M. Hur, J.G. Park, K.H. Yang, J.C. Park, J.R. Park, S.S. Chun, J.S. Choi, and J.W. Choi Effect of methanol extract of Zanthoxylum piperitum leaves and of its compound, protocatechuic acid, on hepatic drug metabolizing enzymes and lipid peroxidation in rats Biosci. Biotechnol. Biochem. 67 2003 945 950
    • (2003) Biosci. Biotechnol. Biochem. , vol.67 , pp. 945-950
    • Hur, J.M.1    Park, J.G.2    Yang, K.H.3    Park, J.C.4    Park, J.R.5    Chun, S.S.6    Choi, J.S.7    Choi, J.W.8
  • 13
    • 0037784055 scopus 로고    scopus 로고
    • The effect of plant phenolics on the formation of 7,12-dimethylbenz[a] anthracene-DNA adducts and TPA stimulated polymorphonuclear neutrophils chemiluminescence in vitro
    • E. Ignatowicz, B. Balana, S.V. Vulimiri, H. Szaefer, and W. Baer-Dubowska The effect of plant phenolics on the formation of 7,12-dimethylbenz[a] anthracene-DNA adducts and TPA stimulated polymorphonuclear neutrophils chemiluminescence in vitro Toxicology 189 2003 199 209
    • (2003) Toxicology , vol.189 , pp. 199-209
    • Ignatowicz, E.1    Balana, B.2    Vulimiri, S.V.3    Szaefer, H.4    Baer-Dubowska, W.5
  • 14
    • 0038424277 scopus 로고
    • Detoxication and drug metabolism: Conjugation and related systems
    • W.B. Jakoby Detoxication and drug metabolism: conjugation and related systems Methods Enzymol. 77 1981 169 177
    • (1981) Methods Enzymol. , vol.77 , pp. 169-177
    • Jakoby, W.B.1
  • 16
    • 0028206059 scopus 로고
    • Suppression of azoxymethane-induced rat colon aberrant crypt foci by dietary protocatechuic acid
    • T. Kawamori, T. Tanaka, T. Kojima, M. Suzui, M. Ohnishi, and H. Mori Suppression of azoxymethane-induced rat colon aberrant crypt foci by dietary protocatechuic acid Jpn. J. Cancer Res. 85 1994 686 691
    • (1994) Jpn. J. Cancer Res. , vol.85 , pp. 686-691
    • Kawamori, T.1    Tanaka, T.2    Kojima, T.3    Suzui, M.4    Ohnishi, M.5    Mori, H.6
  • 18
    • 0013458164 scopus 로고    scopus 로고
    • Modulation of hepatic and renal glutathione S-transferase by naturally occurring plant phenolics in rat and mouse
    • I.T. Johnson G.R. Fenwick Royal Society of Chemistry Cambridge
    • V. Krajka-Kuźniak, J. Gnojkowski, and W. Baer-Dubowska Modulation of hepatic and renal glutathione S-transferase by naturally occurring plant phenolics in rat and mouse I.T. Johnson G.R. Fenwick Dietary Anticarcinogens and Antimutagens: Chemical and Biological Aspects 2000 Royal Society of Chemistry Cambridge 181 183
    • (2000) Dietary Anticarcinogens and Antimutagens: Chemical and Biological Aspects , pp. 181-183
    • Krajka-Kuźniak, V.1    Gnojkowski, J.2    Baer-Dubowska, W.3
  • 19
    • 4043083497 scopus 로고    scopus 로고
    • Modulation of 3-methylcholanthrene-induced rat hepatic and renal cytochrome P450 and phase II enzymes by plant phenols: Protocatechuic and tannic acids
    • V. Krajka-Kuźniak, H. Szaefer, and W. Baer-Dubowska Modulation of 3-methylcholanthrene-induced rat hepatic and renal cytochrome P450 and phase II enzymes by plant phenols: protocatechuic and tannic acids Toxicol. Lett. 152 2004 117 126
    • (2004) Toxicol. Lett. , vol.152 , pp. 117-126
    • Krajka-Kuźniak, V.1    Szaefer, H.2    Baer-Dubowska, W.3
  • 20
    • 0014949207 scopus 로고
    • Cleavage of structural proteins during the assembly of the head of bacteriophage T4
    • U.K. Laemmli Cleavage of structural proteins during the assembly of the head of bacteriophage T4 Nature 227 1970 680 685
    • (1970) Nature , vol.227 , pp. 680-685
    • Laemmli, U.K.1
  • 22
    • 0001744224 scopus 로고
    • Plant phenolics
    • J.B. Harbone Academic Press London
    • K.R. Markham Plant phenolics J.B. Harbone Methods in Plant Biochemistry 1989 Academic Press London 197 235
    • (1989) Methods in Plant Biochemistry , pp. 197-235
    • Markham, K.R.1
  • 23
    • 0023927609 scopus 로고
    • Exceptional activity of tannic acid among naturally occurring plant phenols in protecting against 7,12-dimethylbenz(a)anthracene-, benzo(a)pyrene-, 3-methylcholantrene-, and N-methyl-N-nitrosourea-induced skin tumorigenesis in mice
    • H. Mukhtar, M. Das, W.A. Khan, Z.Y. Wang, D.P. Bik, and D.R. Bickers Exceptional activity of tannic acid among naturally occurring plant phenols in protecting against 7,12-dimethylbenz(a)anthracene-, benzo(a)pyrene-, 3-methylcholantrene-, and N-methyl-N-nitrosourea-induced skin tumorigenesis in mice Cancer Res. 48 1988 2361 2365
    • (1988) Cancer Res. , vol.48 , pp. 2361-2365
    • Mukhtar, H.1    Das, M.2    Khan, W.A.3    Wang, Z.Y.4    Bik, D.P.5    Bickers, D.R.6
  • 24
    • 0016912063 scopus 로고
    • Molecular biology of the carcinogen 4-nitroquinoline 1-oxide
    • M. Nagao, and T. Sugimura Molecular biology of the carcinogen 4-nitroquinoline 1-oxide Adv. Cancer Res. 23 1976 131 169
    • (1976) Adv. Cancer Res. , vol.23 , pp. 131-169
    • Nagao, M.1    Sugimura, T.2
  • 25
    • 0033637344 scopus 로고    scopus 로고
    • Inhibitory effects of protocatechuic acid on the post-initiation phase of hamster pancreatic carcinogenesis induced by N-nitrosobis(2-oxopropyl)amine
    • H. Nakamura, A. Nishikawa, F. Furukawa, K. Kasahara, M. Miyauchi, H.-Y. Son, and M. Hirose Inhibitory effects of protocatechuic acid on the post-initiation phase of hamster pancreatic carcinogenesis induced by N-nitrosobis(2-oxopropyl)amine Anticancer Res. 20 2000 3423 3427
    • (2000) Anticancer Res. , vol.20 , pp. 3423-3427
    • Nakamura, H.1    Nishikawa, A.2    Furukawa, F.3    Kasahara, K.4    Miyauchi, M.5    Son, H.-Y.6    Hirose, M.7
  • 26
    • 0033791661 scopus 로고    scopus 로고
    • A simple phenolic antioxidant protocatechuic acid enhances tumor promotion and oxidative stress in female ICR mouse skin: Dose- and timing-dependent enhancement and involvement of bioactivation by tyrosinase
    • Y. Nakamura, K. Torikai, Y. Ohto, A. Murakami, T. Tanaka, and H. Ohigashi A simple phenolic antioxidant protocatechuic acid enhances tumor promotion and oxidative stress in female ICR mouse skin: dose- and timing-dependent enhancement and involvement of bioactivation by tyrosinase Carcinogenesis 21 2000 1899 1907
    • (2000) Carcinogenesis , vol.21 , pp. 1899-1907
    • Nakamura, Y.1    Torikai, K.2    Ohto, Y.3    Murakami, A.4    Tanaka, T.5    Ohigashi, H.6
  • 27
    • 0035341886 scopus 로고    scopus 로고
    • A catechol antioxidant protocatechuic acid potentiates inflammatory leukocyte-derived oxidative stress in mouse skin via a tyrosinase bioactivation pathway
    • Y. Nakamura, K. Torikai, and H. Ohigashi A catechol antioxidant protocatechuic acid potentiates inflammatory leukocyte-derived oxidative stress in mouse skin via a tyrosinase bioactivation pathway Free Rad. Biol. Med. 30 2001 967 978
    • (2001) Free Rad. Biol. Med. , vol.30 , pp. 967-978
    • Nakamura, Y.1    Torikai, K.2    Ohigashi, H.3
  • 28
    • 0023227936 scopus 로고
    • Plant phenolics as inhibitors of mutational and precarcinogenic events
    • H. Newmark Plant phenolics as inhibitors of mutational and precarcinogenic events Can. J. Physiol. Pharmacol. 65 1987 461 466
    • (1987) Can. J. Physiol. Pharmacol. , vol.65 , pp. 461-466
    • Newmark, H.1
  • 29
    • 0030925252 scopus 로고    scopus 로고
    • In vivo induction and in vitro inhibition of hepatic cytochrome P450 activity by the benzodiazepine anticonvulsants clonazepam and diazepam
    • R.W. Nims, R.A. Prough, C.R. Jones, D.L. Stockus, K.H. Dragnev, P.E. Thomas, and R.A. Lubet In vivo induction and in vitro inhibition of hepatic cytochrome P450 activity by the benzodiazepine anticonvulsants clonazepam and diazepam Drug Metab. Dispos. 25 1997 750 756
    • (1997) Drug Metab. Dispos. , vol.25 , pp. 750-756
    • Nims, R.W.1    Prough, R.A.2    Jones, C.R.3    Stockus, D.L.4    Dragnev, K.H.5    Thomas, P.E.6    Lubet, R.A.7
  • 30
    • 0030934450 scopus 로고    scopus 로고
    • Inhibitory effects of dietary protocatechuic acid and costunolide on 7,12-dimethylbenz[a]anthracene-induced hamster cheek pouch carcinogenesis
    • M. Ohnishi, N. Yoshimi, T. Kawamori, N. Ino, Y. Hirose, T. Tanaka, J. Yamahara, H. Miyata, and H. Mori Inhibitory effects of dietary protocatechuic acid and costunolide on 7,12-dimethylbenz[a]anthracene-induced hamster cheek pouch carcinogenesis Jpn. J. Cancer Res. 88 1997 111 119
    • (1997) Jpn. J. Cancer Res. , vol.88 , pp. 111-119
    • Ohnishi, M.1    Yoshimi, N.2    Kawamori, T.3    Ino, N.4    Hirose, Y.5    Tanaka, T.6    Yamahara, J.7    Miyata, H.8    Mori, H.9
  • 31
    • 0034089655 scopus 로고    scopus 로고
    • Inactivation of hepatic CYP2E1 by an epoxide of diallyl sulfone
    • P.D. Premdas, R.J. Bowers, and P.-G. Forkert Inactivation of hepatic CYP2E1 by an epoxide of diallyl sulfone J. Pharmacol. Exp. Ther. 293 2000 1112 1120
    • (2000) J. Pharmacol. Exp. Ther. , vol.293 , pp. 1112-1120
    • Premdas, P.D.1    Bowers, R.J.2    Forkert, P.-G.3
  • 32
    • 0027325959 scopus 로고
    • Effects of d-limonene on hepatic microsomal monooxygenase activity and paracetamol-induced glutathione depletion in mouse
    • M.M. Reicks, and D. Crankshaw Effects of d-limonene on hepatic microsomal monooxygenase activity and paracetamol-induced glutathione depletion in mouse Xenobiotica 23 1993 809 819
    • (1993) Xenobiotica , vol.23 , pp. 809-819
    • Reicks, M.M.1    Crankshaw, D.2
  • 33
    • 0022117289 scopus 로고
    • P-Nitrophenol hydroxylation. a microsomal oxidation which is highly inducible by ethanol
    • L.A. Reinke, and M.J. Moyer p-Nitrophenol hydroxylation. A microsomal oxidation which is highly inducible by ethanol Drug Metab. Dispos. 13 1985 548 552
    • (1985) Drug Metab. Dispos. , vol.13 , pp. 548-552
    • Reinke, L.A.1    Moyer, M.J.2
  • 34
    • 0029943044 scopus 로고    scopus 로고
    • Development, pharmacology, role of DT-diaphorase and prospects of the indoloquinone EO9
    • E. Smitskamp-Wilms, H.R. Hendriks, and G.J. Peters Development, pharmacology, role of DT-diaphorase and prospects of the indoloquinone EO9 Gen. Pharmacol. 27 1996 421 429
    • (1996) Gen. Pharmacol. , vol.27 , pp. 421-429
    • Smitskamp-Wilms, E.1    Hendriks, H.R.2    Peters, G.J.3
  • 35
    • 3042641988 scopus 로고    scopus 로고
    • Alteration in phase I and II enzymes activities and polycyclic aromatic hydrocarbons-DNA adduct formation by plant phenolics in mouse epidermis
    • H. Szaefer, M. Cichocki, D. Brauze, and W. Baer-Dubowska Alteration in phase I and II enzymes activities and polycyclic aromatic hydrocarbons-DNA adduct formation by plant phenolics in mouse epidermis Nutr. Cancer 48 2004 70 77
    • (2004) Nutr. Cancer , vol.48 , pp. 70-77
    • Szaefer, H.1    Cichocki, M.2    Brauze, D.3    Baer-Dubowska, W.4
  • 36
    • 0037447620 scopus 로고    scopus 로고
    • Effect of naturally occurring plant phenolics on the induction of drug metabolizing enzymes by o-toluidine
    • H. Szaefer, J. Jodynis-Liebert, M. Cichocki, A. Matuszewska, and W. Baer-Dubowska Effect of naturally occurring plant phenolics on the induction of drug metabolizing enzymes by o-toluidine Toxicology 186 2003 67 77
    • (2003) Toxicology , vol.186 , pp. 67-77
    • Szaefer, H.1    Jodynis-Liebert, J.2    Cichocki, M.3    Matuszewska, A.4    Baer-Dubowska, W.5
  • 37
    • 0028327721 scopus 로고
    • Chemoprevention of 4-nitroquinoline-1-oxide-induced oral carcinogenesis by dietary protocatechuic acid during initiation and post-initiation phase
    • T. Tanaka, T. Kawamori, M. Ohnishi, K. Okamoto, H. Mori, and A. Hara Chemoprevention of 4-nitroquinoline-1-oxide-induced oral carcinogenesis by dietary protocatechuic acid during initiation and post-initiation phase Cancer Res. 54 1994 2359 2365
    • (1994) Cancer Res. , vol.54 , pp. 2359-2365
    • Tanaka, T.1    Kawamori, T.2    Ohnishi, M.3    Okamoto, K.4    Mori, H.5    Hara, A.6
  • 38
    • 0029054192 scopus 로고
    • Chemoprevention of N-methyl-N-nitrosourea-induced rat glandular stomach carcinogenesis by natural product-protocatechuic acid
    • T. Tanaka, M. Ohnishi, T. Kojima, H. Mori, K. Satoh, and A. Hara Chemoprevention of N-methyl-N-nitrosourea-induced rat glandular stomach carcinogenesis by natural product-protocatechuic acid Cancer J. 8 1995 150 156
    • (1995) Cancer J. , vol.8 , pp. 150-156
    • Tanaka, T.1    Ohnishi, M.2    Kojima, T.3    Mori, H.4    Satoh, K.5    Hara, A.6
  • 39
    • 0028953753 scopus 로고
    • Chemoprevention of digestive organs carcinogenesis by natural product protocatechuic acid
    • T. Tanaka, T. Kojima, T. Kawamori, and H. Mori Chemoprevention of digestive organs carcinogenesis by natural product protocatechuic acid Cancer 75 Suppl. 1995 1433 1439
    • (1995) Cancer , vol.75 , Issue.SUPPL. , pp. 1433-1439
    • Tanaka, T.1    Kojima, T.2    Kawamori, T.3    Mori, H.4
  • 40
    • 0027215866 scopus 로고
    • Chemoprevention of diethylnitrosamine-induced hepatocarcinogenesis by a simple phenolic acid, protocatechuic acid in rats
    • T. Tanaka, T. Kojima, T. Kawamori, N. Yoshimi, and H. Mori Chemoprevention of diethylnitrosamine-induced hepatocarcinogenesis by a simple phenolic acid, protocatechuic acid in rats Cancer Res. 53 1993 2775 2779
    • (1993) Cancer Res. , vol.53 , pp. 2775-2779
    • Tanaka, T.1    Kojima, T.2    Kawamori, T.3    Yoshimi, N.4    Mori, H.5
  • 41
    • 0009482260 scopus 로고
    • Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: Procedure and some applications
    • H. Towbin, T. Staehelin, and J. Gordon Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications Proc. Natl. Acad. Sci. U.S.A. 76 1979 4350 4354
    • (1979) Proc. Natl. Acad. Sci. U.S.A. , vol.76 , pp. 4350-4354
    • Towbin, H.1    Staehelin, T.2    Gordon, J.3
  • 42
    • 0031939120 scopus 로고    scopus 로고
    • Inhibitory effect of Hibiscus protocatechuic acid on tumor promotion in mouse skin
    • T.H. Tseng, J.D. Hsu, M.H. Lo, C.Y. Chu, F.P. Chou, C.L. Huang, and C.J. Wang Inhibitory effect of Hibiscus protocatechuic acid on tumor promotion in mouse skin Cancer Lett. 126 1998 199 207
    • (1998) Cancer Lett. , vol.126 , pp. 199-207
    • Tseng, T.H.1    Hsu, J.D.2    Lo, M.H.3    Chu, C.Y.4    Chou, F.P.5    Huang, C.L.6    Wang, C.J.7
  • 43
    • 0009259757 scopus 로고
    • The studies on the constituents and the utilization in Citrus species
    • A. Ueno The studies on the constituents and the utilization in Citrus species Foods Food Ingredients J. 157 1993 46 53
    • (1993) Foods Food Ingredients J. , vol.157 , pp. 46-53
    • Ueno, A.1
  • 44
    • 27444442412 scopus 로고    scopus 로고
    • Chemopreventive potential of compounds in cruciferous vegetables
    • W. Baer-Dubowska A. Bartoszek D. Malejka-Giganti CRC Press Boca Raton FL, USA
    • O. Vang Chemopreventive potential of compounds in cruciferous vegetables W. Baer-Dubowska A. Bartoszek D. Malejka-Giganti Chemopreventive and Carcinogenic Food Components 2005 CRC Press Boca Raton FL, USA 175 194
    • (2005) Chemopreventive and Carcinogenic Food Components , pp. 175-194
    • Vang, O.1
  • 45
    • 0032435478 scopus 로고    scopus 로고
    • A new screening system for NAD(P)H:quinone oxidoreductase (NQO1)-directed antitumor quinones: Identification of a new aziridinylbenzoquinone, RH1, as a NQO1-directed antitumor agent
    • S.L. Winski, R.H.J. Hargreaves, J. Butler, and D. Ross A new screening system for NAD(P)H:quinone oxidoreductase (NQO1)-directed antitumor quinones: identification of a new aziridinylbenzoquinone, RH1, as a NQO1-directed antitumor agent Clin. Cancer Res. 4 1998 3083 3088
    • (1998) Clin. Cancer Res. , vol.4 , pp. 3083-3088
    • Winski, S.L.1    Hargreaves, R.H.J.2    Butler, J.3    Ross, D.4
  • 46
    • 0026592561 scopus 로고
    • Dietary effects on cytochromes P450, xenobiotics metabolism and toxicity
    • C.S. Yang, J.F. Brady, and J.-Y. Hong Dietary effects on cytochromes P450, xenobiotics metabolism and toxicity FASEB J. 6 1992 737 744
    • (1992) FASEB J. , vol.6 , pp. 737-744
    • Yang, C.S.1    Brady, J.F.2    Hong, J.-Y.3
  • 48
    • 0028324459 scopus 로고
    • Cytochrome P450 enzymes as targets for chemoprevention against chemical carcinogenesis and toxicity: Opportunities and limitations
    • C.S. Yang, T.J. Smith, and J.-Y. Hong Cytochrome P450 enzymes as targets for chemoprevention against chemical carcinogenesis and toxicity: opportunities and limitations Cancer Res. 54 Suppl. 1994 1982s 1986s
    • (1994) Cancer Res. , vol.54 , Issue.SUPPL.
    • Yang, C.S.1    Smith, T.J.2    Hong, J.-Y.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.