Modulation of 3-methylcholanthrene-induced rat hepatic and renal cytochrome P450 and phase II enzymes by plant phenols: Protocatechuic and tannic acids

Toxicology Letters

Volumn 152, Issue 2, 2004, Pages 117-126

  Krajka Kuźniak, Violetta ^a   Szaefer, Hanna ^a   Baer Dubowska, Wanda ^a  

^a POZNAN UNIVERSITY OF MEDICAL SCIENCES   (Poland)

Author keywords

3 methylcholanthrene; 7,12 dimethylbenz a anthracene; DMBA; EROD; ethoxyresorufin O deethylase; glutathione S transferase; GST; MC; methoxyresorufin O demethylase; MROD; NAD(P)H:quinone oxidoreductase; NQO1; PAH; PNPH; polycyclic aromatic hydrocarbons

Indexed keywords

3 METHYLCHOLANTHRENE; CYTOCHROME P450 1A1; CYTOCHROME P450 1A2; CYTOCHROME P450 2B; CYTOCHROME P450 2E1; CYTOCHROME P450 ISOENZYME; LIVER ENZYME; PROTOCATECHUIC ACID; TANNIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTIBODY SPECIFICITY; ARTICLE; CANCER INHIBITION; CHEMICAL MUTAGENESIS; COMPARATIVE STUDY; CONTROLLED STUDY; DRUG EFFECT; ENZYME ACTIVATION; ENZYME ACTIVITY; KIDNEY CELL; KIDNEY MICROSOME; LIVER CYTOSOL; LIVER MICROSOME; LIVER MICROSOME METABOLISM; LONG TERM CARE; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; RAT STRAIN; REDUCTION; STATISTICAL ANALYSIS; STATISTICAL SIGNIFICANCE; WESTERN BLOTTING;

ANIMALS; CARCINOGENS; CYTOCHROME P-450 ENZYME SYSTEM; DRUGS, CHINESE HERBAL; ENZYME INDUCTION; HYDROLYZABLE TANNINS; HYDROXYBENZOIC ACIDS; INJECTIONS, INTRAPERITONEAL; KIDNEY; LIVER; MALE; METHYLCHOLANTHRENE; MICROSOMES; PHARMACEUTICAL PREPARATIONS; RATS; RATS, WISTAR;

RATTUS NORVEGICUS;

EID: 4043083497     PISSN: 03784274     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.toxlet.2004.04.016     Document Type: Article

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