A simple phenolic antioxidant protocatechuic acid enhances tumor promotion and oxidative stress in female ICR mouse skin: Dose-and timing-dependent enhancement and involvement of bioactivation by tyrosinase

Carcinogenesis

Volumn 21, Issue 10, 2000, Pages 1899-1907

  Nakamura, Yoshimasa ^a   Torikai, Koji ^a   Ohto, Yoshimi ^a   Murakami, Akira ^b   Tanaka, Takuji ^c   Ohigashi, Hajime ^a  

^a KYOTO UNIVERSITY   (Japan)

^b KINKI UNIVERSITY   (Japan)

^c KANAZAWA MEDICAL UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

1 CHLORO 2,4 DINITROBENZENE; ACETONE; ANTIOXIDANT; ARBUTIN; CYCLINE; DIMETHYLBENZ[A]ANTHRACENE; ENZYME INHIBITOR; GLUTATHIONE; GLUTATHIONE PEROXIDASE; GLUTATHIONE TRANSFERASE; HYDROGEN PEROXIDE; MALONALDEHYDE; MONOPHENOL MONOOXYGENASE; MYELOPEROXIDASE; PHENOL DERIVATIVE; PHORBOL 13 ACETATE 12 MYRISTATE; PROTOCATECHUIC ACID; REACTIVE OXYGEN METABOLITE; THIOBARBITURIC ACID REACTIVE SUBSTANCE;

AEROBIC METABOLISM; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; CANCER INHIBITION; CARCINOGENESIS; CELL INFILTRATION; CONTROLLED STUDY; DOSE TIME EFFECT RELATION; DRUG ACTIVATION; DRUG MEGADOSE; DRUG METABOLISM; DRUG STRUCTURE; ENZYME ACTIVITY; FEMALE; INFLAMMATION; LEUKOCYTE; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; SKIN PAPILLOMA; SKIN TUMOR; TUMOR PROMOTION;

9,10-DIMETHYL-1,2-BENZANTHRACENE; ANIMALS; ANTIOXIDANTS; BIOTRANSFORMATION; CARCINOGENS; DERMATITIS, CONTACT; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG ADMINISTRATION SCHEDULE; DRUG SYNERGISM; FEMALE; GLUTATHIONE; GLUTATHIONE PEROXIDASE; GLUTATHIONE TRANSFERASE; HYDROGEN PEROXIDE; HYDROXYBENZOIC ACIDS; MICE; MICE, INBRED ICR; MONOPHENOL MONOOXYGENASE; OXIDATIVE STRESS; PAPILLOMA; SKIN; SKIN NEOPLASMS; TETRADECANOYLPHORBOL ACETATE;

EID: 0033791661     PISSN: 01433334     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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