Dissecting the role of matrix metalloproteinases (MMP) and integrin αvβ3 in angiogenesis in vitro: Absence of hemopexin C domain bioactivity, but membrane-type 1-MMP and α vβ3 are critical

Cancer Research

Volumn 65, Issue 20, 2005, Pages 9377-9387

  Nisato, Riccardo E ^a   Hosseini, Ghamartaj ^a   Sirrenberg, Christian ^b   Butler, Georgina S ^c   Crabbe, Thomas ^d   Docherty, Andrew J P ^d   Wiesner, Matthias ^b   Murphy, Gillian ^e   Overall, Christopher M ^c   Goodman, Simon L ^b   Pepper, Michael S ^a,f,g  

^a UNIVERSITY OF GENEVA MEDICAL SCHOOL   (Switzerland)

^b MERCK KGAA   (Germany)

^c UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^d UCB PHARMA   (Belgium)

^e UNIVERSITY OF EAST ANGLIA   (United Kingdom)

^f Netcare Unitas Hospital   (South Africa)

^g UNIVERSITY OF PRETORIA   (South Africa)

Author keywords

[No Author keywords available]

Indexed keywords

BATIMASTAT; COLLAGEN GEL; COLLAGEN TYPE 1; CT 1399; CT 1847; ENZYME PRECURSOR; GELATINASE A; HEMOPEXIN; HEMOPEXIN C; HYDROXAMIC ACID; INTERSTITIAL COLLAGENASE; LIPOPOLYSACCHARIDE; MATRIX METALLOPROTEINASE INHIBITOR; NEUTRALIZING ANTIBODY; TISSUE INHIBITOR OF METALLOPROTEINASE 1; TISSUE INHIBITOR OF METALLOPROTEINASE 2; TISSUE INHIBITOR OF METALLOPROTEINASE 3; UNCLASSIFIED DRUG; VITRONECTIN RECEPTOR;

ANGIOGENESIS; ANIMAL CELL; ARTICLE; CELL ADHESION; CELL INVASION; CONTROLLED STUDY; ENDOTHELIUM CELL; ENZYME ACTIVITY; ENZYME INHIBITION; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION;

EID: 27144557959     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-05-1512     Document Type: Article

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