Fibrotic lung fibroblasts show blunted inhibition by cAMP due to deficient cAMP response element-binding protein phosphorylation

Journal of Pharmacology and Experimental Therapeutics

Volumn 315, Issue 2, 2005, Pages 678-687

  Liu, Xiaoqiu ^a   Shu, Qiang Sun ^a   Ostrom, Rennolds S ^a  

^a UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; DNA; FORSKOLIN; PROSTAGLANDIN E2; TRANSFORMING GROWTH FACTOR BETA;

ARTICLE; CELL ACTIVATION; CELL ISOLATION; CELL LINE; CELL PROLIFERATION; CELL STIMULATION; CELL TYPE; COLLAGEN SYNTHESIS; CONTROLLED STUDY; DNA BINDING; DRUG EFFECT; ENZYME ACTIVITY; HUMAN; HUMAN CELL; IDIOPATHIC DISEASE; LUNG FIBROBLAST; LUNG FIBROSIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SERUM; SIGNAL TRANSDUCTION;

BLOTTING, WESTERN; CELL LINE; CELL PROLIFERATION; COLLAGEN; CYCLIC AMP; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; CYCLIC AMP-DEPENDENT PROTEIN KINASES; DINOPROSTONE; DNA; ELECTROPHORETIC MOBILITY SHIFT ASSAY; FIBROBLASTS; FORSKOLIN; HUMANS; PHOSPHORYLATION; PULMONARY FIBROSIS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SMAD PROTEINS; TRANSFORMING GROWTH FACTOR BETA;

EID: 27144555396     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.105.090324     Document Type: Article

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