Decreased prostaglandin E2 synthesis by lung fibroblasts isolated from rats with bleomycin-induced lung fibrosis

International Journal of Experimental Pathology

Volumn 80, Issue 1, 1999, Pages 41-49

  Ogushi, Fumitaka ^a   Endo, Takeshi ^a   Tani, Kenji ^a   Asada, Kanji ^a   Kawano, Tetsuya ^a   Tada, Hiroya ^a   Maniwa, Koji ^a   Sone, Saburo ^a  

^a UNIVERSITY OF TOKUSHIMA   (Japan)

Author keywords

Bleomycin fibrosis; Cyclooxygenase 2; Fibroblast; Prostaglandin E2

Indexed keywords

BLEOMYCIN; CYCLOOXYGENASE 2; PROSTAGLANDIN E2; INDOMETACIN; ISOENZYME; PEROXIDASE; PROSTAGLANDIN SYNTHASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; ENZYME INHIBITION; HUMAN; IMMUNOPATHOGENESIS; INTRATRACHEAL DRUG ADMINISTRATION; LUNG FIBROBLAST; LUNG FIBROSIS; MALE; PRIORITY JOURNAL; PROSTAGLANDIN SYNTHESIS INHIBITION; RAT; ANIMAL; BIOSYNTHESIS; CELL DIVISION; CHEMICALLY INDUCED DISORDER; CULTURE TECHNIQUE; DRUG EFFECT; ENZYME IMMUNOASSAY; FIBROBLAST; LUNG; METABOLISM; PATHOLOGY; WISTAR RAT;

ANIMALS; BLEOMYCIN; CELL CULTURE TECHNIQUES; CELL DIVISION; CYCLOOXYGENASE 2; DINOPROSTONE; FIBROBLASTS; IMMUNOENZYME TECHNIQUES; INDOMETHACIN; ISOENZYMES; LUNG; MALE; PEROXIDASES; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; PULMONARY FIBROSIS; RATS; RATS, WISTAR;

EID: 0032587835     PISSN: 09599673     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2613.1999.00096.x     Document Type: Article

References (31)

1. ASADA K., OGUSHI F., TANI K., KAWAJI K., YASUOKA S., SONE S. & OGURA T. (1993) The role of cell-associated interleukin-1 in bleomycin-induced pulmonary fibrosis in rats. Am. Rev. Respir. Dis. 147, A756.
2. 1 on collagen production and degradation in human fetal lung fibroblasts. Arch. Biochem. 265, 441-446.
3. BITTERMAN P., WEWERS M., RENARD S., ADELBERG S. & CRYSTAL R.G. (1986) Modulation of alveolar macrophage-deriven fibroblasts proliferation by alternative macrophage mediators. J. Clin. Invest. 77, 700-708.
4. CHOMCZYNSKI P. & SACCHI N. (1987) Single step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162, 156-159.
5. CLARK J., MADTES D. & RAGHU G. (1993) Effect of platelet-derived growth factor isoform on human lung fibroblast proliferation and collagen gene expression. Exp. Lung Res. 19, 327-344.
6. CRYSTAL R.G., BITTERMAN P.B., RENNARD S.I., HANCE A.J. & KEOGH B.A. (1984) Interstitial lung diseases of unknown cause -disorders characterized by chronic inflammation of the lower respiratory tract. N. Engl. J. Med. 310, 154-167.
7. 2. J. Biol. Chem. 268, 10368-10371.
8. ELIAS J.A. (1988) Tumor necrosis factor interacts with interleukin-1 and interferon to inhibit fibroblast proliferation via prostaglandin-dependent and independent mechanism. Am. Rev. Respir. Dis. 138, 652-658.
9. ELIAS J.A., FREUNDLICH J., KERN J. & ROSENBLOOM J. (1990) Cytokine networks in the regulation of inflammation and fibrosis in the lung. Chest 97, 1439-1445.
10. ELIAS J.A., ROSSMAN M.D., ZURIER R.B. & DANIELE R.P. (1985a) Human alveolar macrophage inhibition of lung fibroblast growth - a prostaglandin-dependent process. Am. Rev. Respir. Dis. 13, 94-99.
11. ELIAS J.A., ZURIER R.B., SCHREIBER A.D., LEFF J.A. & DANIELE R.P. (1985b) Monocyte inhibition of lung fibroblast growth -relationship to fibroblast prostaglandin production and density-defined monocyte subpopulations. J. Leukoc. Biol. 37, 15-28.
12. 2 synthesis by human fibroblasts. Am. J. Respir. Cell Mol. Biol. 12, 358-365.
13. FENG L., SUN W., XIA Y., TANG W., CHANMUGAM P., SOYOOLA E., WILSON C.B. & HWANG D. (1993) Cloning two isoforms of rat cyclooxygenase - differential regulation of their expression. Arch. Biochem. Biophys. 307, 361-368.
14. 2 synthase (cyclooxygenase) in human monocytes. J. Biol. Chem. 265, 16737-16740.
15. GAULDIE J., JORDANA M. & COX G. (1994) Cytokines and pulmonary fibrosis. Cytokine 4, 931-935.
16. HLA T. & NEILSON K. (1992) Human cyclooxygenase-2 cDNA. Proc. Natl. Acad. Sci. USA 89, 7384-7388.
17. JONES D., CARLTON T., MCINTYRE T., ZIMMERMAN G. & PRESCOTT S. (1993) Molecular cloning of human prostaglandin endoperoxide synthase type 2 and demonstration of expression in response to cytokine. J. Biol. Chem. 268, 9049-9054.
18. KUJUBU D., REDDY S., FLECHER B. & HERSCHMAN H. (1993) Expression of the protein product of the prostaglandin synthase-2/ TIS 10 gene in mitogen stimulated Swiss 3T3 cells. J. Biol. Chem. 26, 5425-5430.
19. MIO T., NAGAI S., KITAICHI M., KAWATANI A. & IZUMI T. (1992) Proliferative characteristics of fibroblast lines derived from open lung biopsy specimens of patients with IPF (UIP). Chest 102, 832-837.
20. O'BANION M.K.W., INN V.D. & YOUNG D.A. (1992) cDNA cloning and functional activity of a glucocorticoid-regulated inflammatory cyclooxygenase. Proc. Natl. Acad. Sci. USA 89, 4888-4892.
21. PHAN S.H., VARANI J. & SMITH D. (1985) Rat lung fibroblast collagen metabolism in bleomycin-induced pulmonary fibrosis. J. Clin. Invest. 76, 241-247.
22. RAGHU G., CHEN Y., RUSCH V. & RABINOVITCH P.S. (1988) Differential proliferation of fibroblasts cultured from normal and fibrotic human lung. Am. Rev. Respir. Dis. 138, 703-708.
23. RICHARDSON C. & EMERY P. (1996) The clinical implications of inhibition of the inducible form of cyclooxygenase. Drug Saf. 15, 249-260.
24. SANGER F., NICKLEN S. & COULSON A.R. (1977) DNA sequencing with chain-terminating inhibitors. Proc. Natl. Acad. Sci. USA 74, 5463-5467.
25. SUWABE A., TAKAHASHI K., YASUI S., ARAI S. & SENDO F. (1988) Bleomycin-stimulated hamster alveolar macrophages release interleukin-1. Am. J. Physiol. 132, 512-520.
26. TANI K., YASUOKA S., OGUSHI F., ASADA K., FUJISAWA K., OZAKI T., SANO N. & &. OGURA T. (1991) Thrombin enhances lung fibroblast proliferation in bleomycin-induced pulmonary fibrosis. Am. J. Respir. Cell Mol. Biol. 5, 34-40.
27. TANI K., YASUOKA S., OGUSHI F., OZAKI T., SANO N. & OGURA T. (1990) Cytotoxic factor for fibroblasts in bronchoalveolar lavage fluid of bleomycin-treated rats. Exp. Lung Res. 16, 293-307.
28. 2 and to express cyclooxygenase-2. J. Clin. Invest. 95, 1861-1868.
29. 2 - distinct roles of cyclooxygenase-1 and 2. J. Biol. Chem. 272, 25693-25699.
30. XIE W., CHIPMAN J.G., ROBERTSON D.L., ERIKSON R.L. & SIMMONS D.L. (1991) Expression of a mitogen-responsive gene encoding prostaglandin synthase is regulated by mRNA splicing. Proc. Natl. Acad. Sci. USA 88, 2692-2696.
31. ZHANG Y., LEE T.C., GUILLEMIN L.B., YU M.-C. & ROM W.N. (1993) Enhance IL-1 β and tumor necrosis factor-α release and messenger RNA expression in macrophages from idiopathic pulmonary fibrosis or after asbestos exposure. J. Immunol. 150, 4188-4196.