A bactericidal cecropin-A peptide with a stabilized α-helical structure possess an increased killing capacity but no proinflammatory activity

Inflammation

Volumn 28, Issue 6, 2004, Pages 337-343

  Fu, Huamei ^a   Björstad, Åse ^a   Dahlgren, Claes ^a   Bylund, Johan ^a  

^a UNIVERSITY OF GOTHENBURG   (Sweden)

Author keywords

Antibacterial peptides; Inflammation; Neutrophils

Indexed keywords

ANTIINFECTIVE AGENT; ANTIINFLAMMATORY AGENT; CECROPIN A;

ALPHA HELIX; AMINO ACID SUBSTITUTION; ANTIBACTERIAL ACTIVITY; ANTIINFLAMMATORY ACTIVITY; ARTICLE; COMPUTER; DRUG MECHANISM; DRUG STRUCTURE; ESCHERICHIA COLI; HELICOBACTER PYLORI; HUMAN; HUMAN CELL; INFLAMMATION; NEUTROPHIL; NONHUMAN; NORMAL HUMAN; PROTEIN STRUCTURE; SIMULATION; STRUCTURE ANALYSIS;

AMINO ACID SEQUENCE; ANTI-BACTERIAL AGENTS; ANTIMICROBIAL CATIONIC PEPTIDES; COMPUTER SIMULATION; ESCHERICHIA COLI; HELICOBACTER PYLORI; HUMANS; INFLAMMATION; MICROBIAL SENSITIVITY TESTS; MODELS, MOLECULAR; NADPH OXIDASE; NEUTROPHILS; PEPTIDES; PROTEIN STRUCTURE, SECONDARY; SUPEROXIDES;

HELICOBACTER PYLORI;

EID: 27144553451     PISSN: 03603997     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10753-004-6644-9     Document Type: Article

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