Identification of residues responsible for ligand recognition and regioisomeric selectivity of lysophosphatidic acid receptors expressed in mammalian cells

Journal of Biological Chemistry

Volumn 280, Issue 41, 2005, Pages 35038-35050

  Fujiwara, Yuko ^a   Sardar, Vineet ^c,d,g   Tokumura, Akira ^e   Baker, Daniel ^a,b   Murakami Murofushi, Kimiko ^f   Parrill, Abby ^a,c,d   Tigyi, Gabor ^a,b,c  

^a UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

^b UNIVERSITY OF TENNESSEE CANCER INSTITUTE   (United States)

^c University of Memphis   (United States)

^d UNIVERSITY OF MEMPHIS   (United States)

^e UNIVERSITY OF TOKUSHIMA   (Japan)

^f OCHANOMIZU UNIVERSITY   (Japan)

^g PFIZER GLOBAL RESEARCH AND DEVELOPMENT   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOSYNTHESIS; COMPLEXATION; COMPUTATIONAL METHODS; INSECT CONTROL; ISOMERS; MATHEMATICAL MODELS; MUTAGENESIS;

GENE RECEPTORS; LIGANDS; REGIOISOMERS; RH7777 CELLS;

CELLS;

ALANINE; ARGININE; FATTY ACID; G PROTEIN COUPLED RECEPTOR; GLUTAMINE; HYDROXYL GROUP; LEUCINE; LYSOPHOSPHATIDIC ACID; LYSOPHOSPHATIDIC ACID 1 RECEPTOR; LYSOPHOSPHATIDIC ACID 2 RECEPTOR; LYSOPHOSPHATIDIC ACID 3 RECEPTOR; LYSOPHOSPHATIDIC ACID RECEPTOR; UNCLASSIFIED DRUG; VALINE;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; BACULOVIRUS; CONTROLLED STUDY; GENE OVEREXPRESSION; GENETIC TRANSFECTION; HALF LIFE TIME; HUMAN; INSECT CELL; MAMMAL CELL; MATHEMATICAL MODEL; MOLECULAR INTERACTION; MOLECULAR RECOGNITION; MULTIGENE FAMILY; MUTATION; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; RAT; RECEPTOR SENSITIVITY; RECEPTOR UPREGULATION; STEREOCHEMISTRY; STRUCTURE ACTIVITY RELATION;

ALANINE; ANIMALS; ARGININE; BACULOVIRIDAE; CALCIUM; CELL LINE; CELL LINE, TUMOR; DOSE-RESPONSE RELATIONSHIP, DRUG; FLOW CYTOMETRY; HUMANS; HYDROGEN-ION CONCENTRATION; INSECTS; KINETICS; LIGANDS; LYSOPHOSPHOLIPIDS; MODELS, CHEMICAL; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; MUTATION; PROTEIN CONFORMATION; PROTEIN STRUCTURE, TERTIARY; RATS; RECEPTORS, LYSOPHOSPHATIDIC ACID; SOFTWARE; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP; TRANSFECTION; VALINE;

INSECTA; MAMMALIA;

EID: 27144538692     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M504351200     Document Type: Article

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