Identification of tumor suppressor loci on the long arm of chromosome 5 in pulmonary large cell neuroendocrine carcinoma

Chest

Volumn 128, Issue 4, 2005, Pages 2999-3003

  Shin, Ju Hye ^a   Rang, Shin Myung ^a   Kim, Young Sam ^a   Shin, Dong Hwan ^a   Chang, Joon ^a   Kim, Sung Kyu ^a   Kim, Se Kyu ^a  

^a Yonsei University College of Medicine   (South Korea)

Author keywords

Chromosome 5q; Large cell neuroendocrine carcinoma; Loss of heterozygosity; Tumor suppressor

Indexed keywords

DNA MARKER; MICROSATELLITE DNA;

ADULT; AGED; ARTICLE; CANCER PATIENT; CHROMOSOME 5Q; CHROMOSOME ANALYSIS; CHROMOSOME ARM; CHROMOSOME BAND; CHROMOSOME DELETION; CLINICAL ARTICLE; CLONING; CONTROLLED STUDY; FEMALE; GENE LOCUS; GENETIC SCREENING; HETEROZYGOSITY LOSS; HUMAN; HUMAN TISSUE; LARGE CELL CARCINOMA; LUNG CARCINOMA; LUNG LARGE CELL NEUROENDOCRINE CARCINOMA; LUNG NON SMALL CELL CANCER; MALE; MICROSATELLITE INSTABILITY; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; TUMOR SUPPRESSOR GENE;

EID: 27144529512     PISSN: 00123692     EISSN: None     Source Type: Journal    
DOI: 10.1378/chest.128.4.2999     Document Type: Article

References (31)

1. Travis WD, Colby TV, Corrin B, et al. Histological typing of lung and pleural tumors. 3rd ed. Berlin, Germany: Spring-Verlag, 1999; 7-12
2. Paci M, Cavazza A, Annessi V, et al. Large cell neuroendocrine carcinoma of the lung: a 10-year clinicopathologic retrospective study. Ann Thorac Surg 2004; 77:1163-1167
3. Takei H, Asamura H, Maeshima A, et al. Large cell neuroendocrine carcinoma of the lung: a clinicopathologic study of 87 cases. J Thorac Cardiovasc Surg 2002; 124:285-292
4. Osada H, Takahashi T. Genetic alterations of multiple tumor suppressors and oncogenes in the carcinogenesis and progression of lung cancer. Oncogene 2002; 21:7421-7434
5. Zöchhauer-Müller S, Gazdar AF, Minna JD. Molecular pathogenesis of lung cancer. Annu Rev Physiol 2002; 64:681-708
6. Hirsch FR, Franklin WA, Gazdar AF, et al. Early detection of lung cancer: clinical perspectives of recent advances in biology and radiology. Clin Cancer Res 2001; 7:5-22
7. Sekido Y, Fong KM, Minna JD. Progress in understanding the molecular pathogenesis of human lung cancer. Biochim Biophys Acta 1998; 1378:F21-F59
8. Ashton-Rickardt PG, Wyllie AH, Bird CC, et al. MCC, a candidate familial polyposis gene in 5q21, shows frequent allele loss in colorectal and lung cancer. Oncogene 1991; 6:1881-1886
9. Fong KM, Zimmerman PV, Smith PJ. Tumor progression and loss of heterozygosity at 5q and 18q in non-small cell lung cancer. Cancer Res 1995; 55:220-223
10. Cooper CA, Bubb VJ, Smithson N, et al. Loss of beterozygosity at 5q21 in non-small cell lung cancer: a frequent event but without evidence of APC mutation. J Pathol 1996; 180:33-37
11. Girard L, Zochbauer-Muller S, Virmani AK, et al. Genome-wide allelotyping of lung cancer identifies new regions of allelic loss, differences between small cell lung cancer and non-small cell lung cancer, and loci clustering. Cancer Res 2000; 60:4894-4906
12. Gorgoulis VG, Mariatos G, Manolis EN, et al. Allelic imbalance at the 5q14 locus is associated with decreased apoptotic rate in non-small cell lung carcinomas (NSCLCs): possible synergistic effect with p53 gene alterations on apoptosis. Lung Cancer 2000; 28:211-224
13. Mendes-da-Silva P, Moreira A, Duro-da-Costa J, et al. Frequent loss of heterozygosity on chromosome 5 in non-small cell lung carcinoma. Mol Pathol 2000; 53:184-187
14. Hiroshima K, Iyoda A, Shibuya K, et al. Genetic alterations in early-stage pulmonary large cell neuroendocrine carcinoma. Cancer 2004; 100:1190-1198
15. Ullmann R, Petzmann S, Sharma A, et al. Chromosomal aberrations in a series of large-cell neuroendocrine carcinomas: unexpected divergence from small-cell carcinoma of the lung. Hum Pathol 2001; 32:1059-1063
16. Onuki N, Wistuba II, Travis WD, et al. Genetic changes in the spectrum of neuroendocrine lung tumors. Cancer 1999; 85:600-607
17. Knudson AG Jr. Mutation and cancer: statistical study of retinoblastoma. Proc Natl Acad Sci U S A 1971; 68:820-823
18. Dresler CM, Ritter JH, Patterson GA, et al. Clinical-pathologic analysis of 40 patients with large cell neuroendocrine carcinoma of the lung. Ann Thorac Surg 1997; 63:180-185
19. Peng WX, Sano T, Oyama T, et al. Large cell neuroendocrine carcinoma of the lung: a comparison with large cell carcinoma with neuroendocrine morphology and small cell carcinoma. Lung Cancer 2005; 47:225-233
20. Tavassoli M, Steingrimsdottir H, Pierce E, et al. Loss of heterozygosity on chromosome 5q in ovarian cancer is frequently accompanied by TP53 mutation and identifies a tumour suppressor gene locus at 5ql3.1-21. Br J Cancer 1996; 74:11.5-119
21. Tamura G, Ogasawara S, Nishizuka S, et al. Two distinct regions of deletion on the long arm of chromosome 5 in differentiated adenocarcinomas of the stomach. Cancer Res 1996; 56:612-615
22. Ogasawara S, Tamura G, Maesawa C, et al. Common deleted region on the long arm of chromosome 5 in esophageal carcinoma. Gastroenterology 1996; 110:52-57
23. Peng HQ, Liu L, Goss PE, et al. Chromosomal deletions occur in restricted regions of 5q in testicular germ cell cancer. Oncogene 1999; 18:3277-3283
24. Horrigan SK, Westbrook CA, Kim AH, et al. Polymerase chain reaction-based diagnosis of del (5q) in acute myeloid leukemia and myelodysplastic syndrome identifies a minimal deletion interval. Blood 1996; 88:2665-2670
25. Achille A, Baron A, Zamboni G, et al. Chromosome 5 allelic losses are early events in tumours of the papilla of Vater and occur at sites similar to those of gastric cancer. Br J Cancer 1998; 78:1653-1660
26. D'Amico D, Carbone DP, Johnson BE, et al. Polymorphic sites within the MCC and APC loci reveal very frequent loss of heterozygosity in human small cell lung cancer. Cancer Res 1992; 52:1996-1999
27. Hosoe S, Ueno K, Shigedo Y, et al. A frequent deletion of chromosome5q21 in advanced small cell and non-small cell carcinoma of the lung. Cancer Res 1994; 54:1787-1790
28. Wieland I, Bohm M, Arden KC, et al. Allelic deletion mapping on chromosome 5 in human carcinomas. Oncogene 1996; 12:97-102
29. Taniguchi T, Lamphier MS, Tanaka N. IRF-1: the transcription factor linking the interferon response and oncogenesis. Biochim Biophys Acta 1997; 1333:M9-M17
30. Harada H, Kondo T, Ogawa S, et al. Accelerated exon skipping of IRF-1 mRNA inhuman myelodysplasia/leukemia: a possible mechanism of tumor suppressor inactivation. Oncogene 1994; 9:3313-3320
31. Nozawa H, Oda E, Ueda S, et al. Functionally inactivating point mutation in the tumor suppressor IRF-1 gene identified in human gastric cancer. Int J Cancer 1998; 77:522-527