-
1
-
-
13444273224
-
Nature and nurture. Lessons from chemical carcinogenesis
-
Luch, A. Nature and nurture. Lessons from chemical carcinogenesis. Nat. Rev. Cancer 2005, 5, 113-125.
-
(2005)
Nat. Rev. Cancer
, vol.5
, pp. 113-125
-
-
Luch, A.1
-
2
-
-
0034693727
-
Strategies and testing methods for identifying mutagenic risks
-
MacGregor, J. T.; Casciano, D.; Muller, L. Strategies and testing methods for identifying mutagenic risks. Mutat. Res. 2000, 455, 3-20.
-
(2000)
Mutat. Res.
, vol.455
, pp. 3-20
-
-
MacGregor, J.T.1
Casciano, D.2
Muller, L.3
-
3
-
-
0030956198
-
Recent advances in the construction of bacterial genotoxicity assays
-
Josephy, P. D.; Cruz, P.; Nohmi, T. Recent advances in the construction of bacterial genotoxicity assays. Mutat. Res. 1997, 386, 1-23.
-
(1997)
Mutat. Res.
, vol.386
, pp. 1-23
-
-
Josephy, P.D.1
Cruz, P.2
Nohmi, T.3
-
4
-
-
0020533372
-
Revised methods for the Salmonella mutagenicity test
-
Maron, D. M.; Ames, B. N. Revised methods for the Salmonella mutagenicity test. Mutat. Res. 1983, 113, 173-215.
-
(1983)
Mutat. Res.
, vol.113
, pp. 173-215
-
-
Maron, D.M.1
Ames, B.N.2
-
5
-
-
0000300233
-
Detection of carcinogens as mutagens in the Salmonella/microsome test: Assay of 300 chemicals: Discussion
-
McCann, J.; Ames, B. N. Detection of carcinogens as mutagens in the Salmonella/microsome test: assay of 300 chemicals: discussion. Proc. Natl. Acad. Sci. U.S.A. 1976, 73, 950-954.
-
(1976)
Proc. Natl. Acad. Sci. U.S.A.
, vol.73
, pp. 950-954
-
-
McCann, J.1
Ames, B.N.2
-
6
-
-
0034693731
-
The Ames Salmonella/microsome mutagenicity assay
-
Mortelmans, K.; Zeiger, E. The Ames Salmonella/microsome mutagenicity assay. Mutat. Res. 2000, 455, 29-60.
-
(2000)
Mutat. Res.
, vol.455
, pp. 29-60
-
-
Mortelmans, K.1
Zeiger, E.2
-
7
-
-
0034693730
-
The in vitro micronucleus technique
-
Fenech, M. The in vitro micronucleus technique. Mutat. Res. 2000, 455, 81-95.
-
(2000)
Mutat. Res.
, vol.455
, pp. 81-95
-
-
Fenech, M.1
-
8
-
-
0033501585
-
New approaches to estimating the mutagenic potential of chemicals
-
Marzin, D. New approaches to estimating the mutagenic potential of chemicals. Cell Biol. Toxicol. 1999, 15, 359-365.
-
(1999)
Cell Biol. Toxicol.
, vol.15
, pp. 359-365
-
-
Marzin, D.1
-
9
-
-
0037186905
-
In vitro preclinical lead optimisation technologies (PLOTs) in pharmaceutical development
-
Atterwill, C. K.; Wing, M. G. In vitro preclinical lead optimisation technologies (PLOTs) in pharmaceutical development. Toxicol. Lett. 2002, 127, 143-151.
-
(2002)
Toxicol. Lett.
, vol.127
, pp. 143-151
-
-
Atterwill, C.K.1
Wing, M.G.2
-
10
-
-
0003563136
-
-
Cambridge University Press: Cambridge, U.K.
-
Kirkland, D. J., Gatehouse, D. G., Scott, D., Cole, J., Richold, M., Eds.; Basic Mutagenicity Tests: UKEMS Recommended Procedures; Cambridge University Press: Cambridge, U.K., 1990.
-
(1990)
Basic Mutagenicity Tests: UKEMS Recommended Procedures
-
-
Kirkland, D.J.1
Gatehouse, D.G.2
Scott, D.3
Cole, J.4
Richold, M.5
-
11
-
-
0028360779
-
Recommendations for the performance of bacterial mutation assays
-
Gatehouse, D.; Haworth, S.; Cebula, T.; Gocke, E.; Kier, L.; Matsushima, T.; Melcion, C.; Nohmi, T.; Ohta, T.; Venitt, S.; Zieger, E. Recommendations for the performance of bacterial mutation assays. Mutat. Res. 1994, 312, 217-233.
-
(1994)
Mutat. Res.
, vol.312
, pp. 217-233
-
-
Gatehouse, D.1
Haworth, S.2
Cebula, T.3
Gocke, E.4
Kier, L.5
Matsushima, T.6
Melcion, C.7
Nohmi, T.8
Ohta, T.9
Venitt, S.10
Zieger, E.11
-
12
-
-
0042355457
-
In silico prediction of drug toxicity
-
Dearden, J. C. In silico prediction of drug toxicity. J. Comput. Aided. Mol. Des. 2003, 17, 119-127.
-
(2003)
J. Comput. Aided. Mol. Des.
, vol.17
, pp. 119-127
-
-
Dearden, J.C.1
-
13
-
-
12144257810
-
Derivation and validation of toxicophores for mutagenicity prediction
-
Kazius, J.; McGuire, R.; Bursi, R. Derivation and validation of toxicophores for mutagenicity prediction. J. Med. Chem. 2005, 48, 312-320.
-
(2005)
J. Med. Chem.
, vol.48
, pp. 312-320
-
-
Kazius, J.1
McGuire, R.2
Bursi, R.3
-
14
-
-
0142088806
-
Quantitative structure-activity relationships for predicting mutagenicity and carcinogenicity
-
Patlewicz, G.; Rodford, R.; Walker, J. D. Quantitative structure-activity relationships for predicting mutagenicity and carcinogenicity. Environ. Toxicol. Chem. 2003, 22, 1885-1893.
-
(2003)
Environ. Toxicol. Chem.
, vol.22
, pp. 1885-1893
-
-
Patlewicz, G.1
Rodford, R.2
Walker, J.D.3
-
15
-
-
3242727566
-
Searching for an enhanced predictive tool for mutagenicity
-
Klopman, G.; Zhu, H.; Fuller, M. A.; Saiakhov, R. D. Searching for an enhanced predictive tool for mutagenicity. SAK QSAR Environ. Res. 2004, 15, 251-263.
-
(2004)
SAK QSAR Environ. Res.
, vol.15
, pp. 251-263
-
-
Klopman, G.1
Zhu, H.2
Fuller, M.A.3
Saiakhov, R.D.4
-
16
-
-
0036319482
-
Comparison of the computer programs DEREK and TOPKAT to predict bacterial mutagenicity. Deductive estimate of risk from existing knowledge. Toxicity prediction by komputer assisted technology
-
Cariello, N. F.; Wilson, J. D.; Britt, B. H.; Wedd, D. J.; Burlinson, B.; Gombar, V. Comparison of the computer programs DEREK and TOPKAT to predict bacterial mutagenicity. Deductive estimate of risk from existing knowledge. Toxicity prediction by komputer assisted technology. Mutagenesis 2002, 17, 321-329.
-
(2002)
Mutagenesis
, vol.17
, pp. 321-329
-
-
Cariello, N.F.1
Wilson, J.D.2
Britt, B.H.3
Wedd, D.J.4
Burlinson, B.5
Gombar, V.6
-
17
-
-
2442548465
-
Assessment of the sensitivity of the computational programs DEREK, TOPKAT, and MCASE in the prediction of the genotoxicity of pharmaceutical molecules
-
Snyder, R. D.; Pearl, G. S.; Mandakas, G.; Choy, W. N.; Goodsaid, F.; Rosenblum, I. Y. Assessment of the sensitivity of the computational programs DEREK, TOPKAT, and MCASE in the prediction of the genotoxicity of pharmaceutical molecules. Environ. Mol. Mutagen. 2004, 43, 143-158.
-
(2004)
Environ. Mol. Mutagen.
, vol.43
, pp. 143-158
-
-
Snyder, R.D.1
Pearl, G.S.2
Mandakas, G.3
Choy, W.N.4
Goodsaid, F.5
Rosenblum, I.Y.6
-
18
-
-
0025094417
-
New structural concepts for predicting carcinogenicity in rodents: An artificial intelligence approach
-
Rosenkranz, H. S.; Klopman, G. New structural concepts for predicting carcinogenicity in rodents: an artificial intelligence approach. Teratog., Carcinog., Mutagen. 1990, 10, 73-88.
-
(1990)
Teratog., Carcinog., Mutagen.
, vol.10
, pp. 73-88
-
-
Rosenkranz, H.S.1
Klopman, G.2
-
19
-
-
0035899174
-
Toward the design of chemical libraries for mass screening biased against mutagenic compounds
-
Llorens, O.; Ferez, J. J.; Villar, H. O. Toward the design of chemical libraries for mass screening biased against mutagenic compounds. J. Med. Chem. 2001, 44, 2793-2804.
-
(2001)
J. Med. Chem.
, vol.44
, pp. 2793-2804
-
-
Llorens, O.1
Ferez, J.J.2
Villar, H.O.3
-
20
-
-
0037066184
-
Investigation of structural and electronic biases in mutagenic compounds
-
Llorens, O.; Ferez, J. J.; Villar, H. O. Investigation of structural and electronic biases in mutagenic compounds. Int. J. Quantum Chem. 2002, 88, 107-117.
-
(2002)
Int. J. Quantum Chem.
, vol.88
, pp. 107-117
-
-
Llorens, O.1
Ferez, J.J.2
Villar, H.O.3
-
21
-
-
33644509882
-
To market, to market-2003
-
Doherty, A. M., Ed.; Elsevier Acadmic Press: Amsterdam
-
See, for example, the following. Hegde, S.; Carter, J. To Market, To Market-2003. In Annual Reports in Medicinal Chemistry; Doherty, A. M., Ed.; Elsevier Acadmic Press: Amsterdam, 2004; Vol. 39, pp 337-368.
-
(2004)
Annual Reports in Medicinal Chemistry
, vol.39
, pp. 337-368
-
-
Hegde, S.1
Carter, J.2
-
22
-
-
0003005323
-
Exhaustive enumeration of molecular substructures
-
Bone, R. G. A.; Villar, H. O. Exhaustive enumeration of molecular substructures. J. Comput. Chem. 1997, 18, 86-107.
-
(1997)
J. Comput. Chem.
, vol.18
, pp. 86-107
-
-
Bone, R.G.A.1
Villar, H.O.2
-
23
-
-
18244365837
-
HierS: Hierarchical scaffold clustering using topological chemical graphs
-
Wilkens, S. J.; Janes, J.; Su, A. I. HierS: Hierarchical scaffold clustering using topological chemical graphs. J. Med. Chem. 2005, 48, 3182-3193.
-
(2005)
J. Med. Chem.
, vol.48
, pp. 3182-3193
-
-
Wilkens, S.J.1
Janes, J.2
Su, A.I.3
-
24
-
-
0004094098
-
-
Lilienfeld, D. E., Stolley, P. D., Eds.; Oxford University Press: New York
-
Foundations of Epidemiology, 3rd ed.; Lilienfeld, D. E., Stolley, P. D., Eds.; Oxford University Press: New York, 1994.
-
(1994)
Foundations of Epidemiology, 3rd Ed.
-
-
|