Derivation and validation of toxicophores for mutagenicity prediction

Journal of Medicinal Chemistry

Volumn 48, Issue 1, 2005, Pages 312-320

  Kazius, Jeroen ^a,b   McGuire, Ross ^a   Bursi, Roberta ^a  

^a NV ORGANON   (Netherlands)

^b LEIDEN UNIVERSITY   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ALIPHATIC COMPOUND; AROMATIC AMINE; AROMATIC NITRO COMPOUND; AZO COMPOUND; HALIDE; HETEROCYCLIC COMPOUND; MUTAGENIC AGENT; NITROSO DERIVATIVE;

ACCURACY; AMES TEST; ARTICLE; CHEMICAL STRUCTURE; DRUG DETOXIFICATION; DRUG STRUCTURE; MEDICAL LITERATURE; MUTAGENICITY; RELIABILITY; TOXICITY; VALIDATION PROCESS;

DATABASES, FACTUAL; MODELS, THEORETICAL; MUTAGENICITY TESTS; MUTAGENS; PREDICTIVE VALUE OF TESTS; REPRODUCIBILITY OF RESULTS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 12144257810     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm040835a     Document Type: Article

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