Heme oxygenase is induced in nephrotoxic nephritis and hemin, a stimulator of heme oxygenase synthesis, ameliorates disease

Kidney International

Volumn 53, Issue 3, 1998, Pages 672-678

  Mosley, Karen ^a   Wembridge, David E ^a   Cattell, Victoria ^a   Cook, H Terence ^a,b  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

^b HAMMERSMITH HOSPITAL   (United Kingdom)

Author keywords

Heme oxygenase; Inflammation; Nephrotoxic nephritis; Oxidative stress; Proteinuria

Indexed keywords

BILIVERDIN; CARBON DIOXIDE; HEME; HEME OXYGENASE; HEMIN; IRON;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME INDUCTION; IMMUNE COMPLEX NEPHRITIS; INFLAMMATION; KIDNEY BIOPSY; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROLIFERATIVE GLOMERULONEPHRITIS; PROTEINURIA; RAT;

EID: 0031914416     PISSN: 00852538     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1523-1755.1998.00798.x     Document Type: Article

References (39)

1. MAINES MD: New developments in the regulation of heme metabolism and their implications. CRC Crit Rev Toxicol 12:241-314, 1984
2. MAINES MD: Heme oxygensase: Funtion, multiplicity, regulatory mechanisms, and clinical applications. FASEB J 2:2557-2568, 1988
3. CHOI AMK, ALAM J: Heme oxygenase-1: Function, regulation, and implication of a novel stress-inducible protein in oxidant-induced lung injury. Am J Respir Cell Mol Biol 15:9-19, 1996
4. SHIBAHARA S, MÜLLER RM, TAGUCHI H: Transcriptional control of rat heme oxygenase by heat shock. J Biol Chem 262:12889-12892, 1987
5. LAVROVSKY Y, SCHWARTZMAN ML, LEVERE RD, KAPPAS A, ABRAHAM NG: Identification of binding sites for transcription factors NF-kappa B and AP-2 in the promoter region of the human hemeoxygenase 1 gene. Proc Natl Acad Sci USA 91:5987-5991, 1994
6. ALAM J, ZHINING D: Distal AP-1 binding sites mediate basal level enhancement and TPA induction of the mouse heme oxygenase-1 gene. J Biol Chem 267:21894-21900, 1992
7. STOCKER R, YAMAMOTO Y, MCDONAGH AF, GLAZER AN, AMES BN: Bilirubin is an antioxidant of possible physiological importance. Science 235:1043-1046, 1987
8. NAKAGAMI T, TOYOMURA K, KIMOSHITA T, MORISAWA S: A beneficial role of bile pigments as an endogenous tissue protector: Anticomplement effects of biliverdin and conjugated bilirubin. Biochim Biophys Acta 1158:189-193, 1993
9. INGI T, CHENG J, RONNETT GV: Carbon monoxide: An endogenous modulator of the nitric oxide-cyclic GMP signaling system. Neuron 16:835-842, 1996
10. JUCKETT MB, BALLA J, BALLA G, JESSURUN J, JACOB HS, VERCEL-LOTTI GM: Ferritin protects endothelial cells from oxidized low density lipoprotein in vitro. Am J Pathol 147:782-789, 1995
11. LEE PJ, ALAM J, WIEGAND GW, CHOI AMK: Overexpression of heme oxygenase-1 in human pulmonary epithelial cells results in cell growth arrest and increased resistance to hyperoxia. Proc Natl Acad Sci USA 93:10393-10398, 1996
12. ABRAHAM NG, LAVROVSKY Y, SCHWARTZMAN ML, STOLTZ RA, LEVERE RD, GERRITSEN ME, SHIBAHARA S, KAPPAS A: Transfection of the human heme oxygenase gene into rabbit coronary microvessel endothelial cells: Protective effect against heme and hemoglobin toxicity. Proc Natl Acad Sci USA 92:6798-6802, 1995
13. WILLIS D, MOORE AR, FREDERICK R, WILLOUGHBY DA: Heme oxygenase: A novel target for the modulation of the inflammatory response. Nature Med 2:87-90, 1996
14. 2 negatively modulates interleukin-1-induced heme oxygenase-1 mRNA. Biochem Biophys Res Commun 212:617-623, 1995
15. SHAH SV: The role of reactive oxygen metabolites in glomerular disease. Annu Rev Physiol 57:245-262, 1995
16. UNANUE ER, DIXON FJ: Experimental glomerulonephritis. VI. The autologous phase of nephrotoxic serum nephritis. J Exp Med 121:715-725, 1965
17. COOK HT, CATTELL V, SMITH J, SALMON JA, MONCADA S: Effect of a thromboxane synthetase inhibitor on eicosanoid synthesis and glomerular injury during acute unilateral glomerulonephritis in the rat. Clin Nephrol 26:195-202, 1986
18. GERDES J, BECKER MHG, KEY G: Immunohistochemical detection of tumour growth fraction (Ki-67 antigen) in formalin fixed and routinely processed tissues. J Pathol 168:85-86, 1992
19. PASCHEN W, UTO A, DJURICIC B, SCHMITT J: Heme oxygenase expression after reversible ischemia of rat brain. Neurosci Letts 180:5-8, 1994
20. AGARWAL A, KIM Y, MATAS AJ, ALAM J, NATH KA: Gas-generating systems in acute renal allograft rejection in the rat - Co-induction of heme oxygenase and nitric oxide synthase. Transplantation 61:93-98, 1996
21. KEYSE SM, TYRELL RM: Heme oxygenase is the major 32-kDa stress protein induced in human skin fibroblasts by UVA radiation, hydrogen peroxide, and sodium arsenite. Proc Natl Acad Sci USA 86:99-103, 1989
22. CANTONI L, ROSSI C, RIZZARDINI M, GADINA M, GHEZZI P: Interleukin-1 and tumor necrosis factor induce hepatic heme oxygenase. Biochem J 279:891-894, 1991
23. MOTTERLINI R, HIDALGO A, SAMMUT I, SHAH KA, MOHAMMED S, SRAI K, GREEN CJ: A precursor of the nitric oxide donor SIN-1 modulates the stress protein heme oxygenase-1 in rat liver. Biochem Biophys Res Commun 225:167-172, 1996
24. YEE EL, PITT BR, BILLIAR TR, KIM YM: Effect of nitric oxide on heme metabolism in pulmonary artery endothelial cells. Am J Physiol Lung Cell Mol Physiol 271:L512-L518, 1996
25. POLLA BS, STUBBE H, KANTENGWA S, MARIDONNEAU-PARINI I, JACQUIER-SARLIN MR: Differential induction of stress proteins and functional effects of heat shock in human phagocytes. Inflammation 19:363-371, 1995
26. VOGT BA, SHANLEY TP, CROATT A, ALAM J, JOHSON KJ, NATH KA: Glomerular inflammation induces resistance to tubular injury in the rat. A novel form of acquired heme oxygenase-dependent resistance to renal injury. J Clin Invest 98:2139-2145, 1996
27. SCHNAPER HW, KOPP JB, PONCELET AC, HUBCHAK SC, STETLER-STEVENSON WG, KLOTMAN PE, KLEINMAN HK: Increased expression of extracellular matrix proteins and decreased expression of matrix proteases after serial passage of glomerular mesangial cells. J Cell Sci 109:2521-2528, 1996
28. REHAN A, JOHNSON KJ, WIGGINS RC, KUNKEL RG, WARD PA: Evidence for the role oxygen radicals in nephrotoxic nephritis. Lab Invest 51:396-403, 1984
29. REHAN A, JOHNSON KJ, KUNKEL RG, WIGGINS RC: Role of oxygen radicals in phorbol myristate acetate-induced glomerular injury. Kidney Int 27:503-511, 1985
30. NEUZIL J, STOCKER R: Free and albumin bound bilirubin are efficient co-antioxidants for alpha-tocopherol inhibiting plasma and low density lipoprotein lipid peroxidation. J Biol Chem 269:16712-16719, 1994
31. STOCKER R, GLAZER AN, AMES BN: Antioxidant activity of albumin-bound bilirubin. Proc Natl Acad Sci USA 84:5918-5922, 1987
32. NATH KA, BALLA G, VERCELLOTTI GM, BALLA J, JACOB HS, LEVITT MD, ROSENBERG ME: Induction of heme oxygenase is a rapid protective response to rhabdomyolysis in the rat. J Clin Invest 90:267-270, 1992
33. EISENSTEIN R, GARCIA-MAYOI. D, PETTINGELL W, MUNRO H: Regulation of ferritin and heme oxygenase synthesis in rat fibroblasts by different forms of iron. Proc Natl Acad Sci USA 88:688-692, 1991
34. BAUD L, ARDAILLOU R: Reactive oxygen species: Production and role in the kidney. Am J Physiol 251:F765-F776, 1986
35. BALLA G, JACOB HS, BALLA J, ROSENBERG M, NATH K, APPLE F, EATON JW, VERCELOTTI GM: Ferritin: A cytoprotective antioxidant strategem of endothelium. J Biol Chem 267:18148-18153, 1992
36. BOYCE NW, HOLDSWORTH SR: Hydroxyl radical mediation of immune renal injury by desferrioxamine. Kidney Int 30:813-817, 1986
37. YOSHIOKA T, MITARAI T, KON V, DEEN WM, RENNKE HG, ICHIKAWA I: Role of angiotensin II in an overt functional proteinuria. Kidney Int 30:538-545, 1986
38. FERRARIO R, TAKAHASHI K, FOGO A, BADR KF, MUNGER KA: Consequences of acute nitric oxide synthesis inhibition in experimental glomerulonephritis. J Am Soc Nephrol 4:1847-1854, 1994
39. MONCADA S, PALMER RMJ, HIGGS EA: Nitric oxide: physiology, pathophysiology and pharmacology. Pharmacol Rev 43:109-142, 1991