Erv1 mediates the Mia40-dependent protein import pathway and provides a functional link to the respiratory chain by shuttling electrons to cytochrome c

Journal of Molecular Biology

Volumn 353, Issue 5, 2005, Pages 937-944

  Allen, Scott ^a   Balabanidou, Vassilia ^b,c   Sideris, Dionisia P ^b,c   Lisowsky, Thomas ^d   Tokatlidis, Kostas ^b,c  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

^b INSTITUTE OF MOLECULAR BIOLOGY AND BIOTECHNOLOGY   (Greece)

^c UNIVERSITY OF CRETE   (Greece)

^d TU DORTMUND UNIVERSITY   (Germany)

Author keywords

Cytochrome c; Erv1; Mitochondria; Oxidative folding; Protein assembly

Indexed keywords

CYTOCHROME C; ERV1 PROTEIN; FLAVINE ADENINE NUCLEOTIDE; MITOCHONDRIAL PROTEIN; THIOL OXIDASE; UNCLASSIFIED DRUG;

ARTICLE; BIOGENESIS; ELECTRON; MITOCHONDRION; PRIORITY JOURNAL; RESPIRATORY CHAIN; VEGETATIVE GROWTH;

EID: 27144438677     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmb.2005.08.049     Document Type: Article

References (40)

1. M. Kurz, H. Martin, J. Rassow, N. Pfanner, and M.T. Ryan Biogenesis of Tim proteins of the mitochondrial carrier import pathway: differential targeting mechanisms and crossing over with the main import pathway Mol. Biol. Cell. 10 1999 2461 2474
2. H. Lu, S. Allen, L. Wardleworth, P. Savory, and K. Tokatlidis Functional TIM10 chaperone assembly is redox-regulated in vivo J. Biol. Chem. 279 2004 18952 18958
3. T. Lutz, W. Neupert, and J.M. Herrmann Import of small Tim proteins into the mitochondrial intermembrane space EMBO J. 22 2003 4400 4408
4. Y. Furukawa, A.S. Torres, and T.V. O'Halloran Oxygen-induced maturation of SOD1: a key role for disulfide formation by the copper chaperone CCS EMBO J. 23 2004 2872 2881
5. L.S. Field, Y. Furukawa, T.V. O'Halloran, and V.C. Culotta Factors controlling the uptake of yeast copper/zinc superoxide dismutase into mitochondria J. Biol. Chem. 278 2003 28052 28059
6. F. Arnesano, E. Balatri, L. Banci, I. Bertini, and D.R. Winge Folding studies of Cox17 reveal an important interplay of cysteine oxidation and copper binding Structure (Camb) 13 2005 713 722
7. M.P. Nobrega, S.C. Bandeira, J. Beers, and A. Tzagoloff Characterization of COX19, a widely distributed gene required for expression of mitochondrial cytochrome oxidase J. Biol. Chem. 277 2002 40206 40211
8. H. Lu, A.P. Golovanov, F. Alcock, J.G. Grossmann, S. Allen, L.Y. Lian, and K. Tokatlidis The structural basis of the TIM10 chaperone assembly J. Biol. Chem. 279 2004 18959 18966
9. S. Allen, H. Lu, D. Thornton, and K. Tokatlidis Juxtaposition of the two distal CX3C motifs via intrachain disulfide bonding is essential for the folding of Tim10 J. Biol. Chem. 278 2003 38505 38513
10. S.P. Curran, D. Leuenberger, E. Schmidt, and C.M. Koehler The role of the Tim8p-Tim13p complex in a conserved import pathway for mitochondrial polytopic inner membrane proteins J. Cell. Biol. 158 2002 1017 1027
11. S.P. Curran, D. Leuenberger, W. Oppliger, and C.M. Koehler The Tim9p-Tim10p complex binds to the transmembrane domains of the ADP/ATP carrier EMBO J. 21 2002 942 953
12. A. Chacinska, S. Pfannschmidt, N. Wiedemann, V. Kozjak, L.K. Sanjuan Szklarz, and A. Schulze-Specking Essential role of Mia40 in import and assembly of mitochondrial intermembrane space proteins EMBO J. 23 2004 3735 3746
13. M. Naoe, Y. Ohwa, D. Ishikawa, C. Ohshima, S. Nishikawa, H. Yamamoto, and T. Endo Identification of Tim40 that mediates protein sorting to the mitochondrial intermembrane space J. Biol. Chem. 279 2004 47815 47821
14. N. Terziyska, T. Lutz, C. Kozany, D. Mokranjac, N. Mesecke, and W. Neupert Mia40, a novel factor for protein import into the intermembrane space of mitochondria is able to bind metal ions FEBS Letters 579 2005 179 184
15. N. Mesecke, N. Terziyska, C. Kozany, F. Baumann, W. Neupert, K. Hell, and J.M. Herrmann A disulfide relay system in the intermembrane space of mitochondria that mediates protein import Cell 121 2005 1059 1069
16. K. Tokatlidis A disulfide relay system in mitochondria Cell 121 2005 965 967
17. J. Lee, G. Hofhaus, and T. Lisowsky Erv1p from Saccharomyces cerevisiae is a FAD-linked sulfhydryl oxidase FEBS Letters 477 2000 62 66
18. D. Becher, J. Kricke, G. Stein, and T. Lisowksy A mutant for the yeast ScERV1 gene displays a new defect in mitochondrial morphology and distribution Yeast 15 1999 1171 1181
19. H. Lange, T. Lisowsky, J. Gerber, U. Muhlenhoff, G. Kispal, and R. Lill An essential function of the mitochondrial sulfhydryl oxidase Erv1p/ALR in the maturation of cytosolic Fe/S proteins EMBO Rep. 2 2001 715 720
20. K. Diekert, A.I. de Kroon, U. Ahting, B. Niggemeyer, W. Neupert, B. de Kruijff, and R. Lill Apocytochrome c requires the TOM complex for translocation across the mitochondrial outer membrane EMBO J. 20 2001 5626 5635
21. N. Wiedemann, V. Kozjak, T. Prinz, M.T. Ryan, C. Meisinger, N. Pfanner, and K.N. Truscott Biogenesis of yeast mitochondrial cytochrome c: a unique relationship to the TOM machinery J. Mol. Biol. 327 2003 465 474
22. S.R. Farrell, and C. Thorpe Augmenter of liver regeneration: a flavin-dependent sulfhydryl oxidase with cytochrome c reductase activity Biochemistry 44 2005 1532 1541
23. B.S. Glick Protein Import into isolated yeast mitochondria Methods Cell. Biol. 34 1991 389 399
24. K. Esser, E. Pratje, and G. Michaelis SOM 1, a small new gene required for mitochondrial inner membrane peptidase function in Saccharomyces cerevisiae Mol. Gen. Genet. 252 1996 437 445
25. P.S. Jan, K. Esser, E. Pratje, and G. Michaelis Som1, a third component of the yeast mitochondrial inner membrane peptidase complex that contains Imp1 and Imp2 Mol. Gen. Genet. 263 2000 483 491
26. M.A. Vergnolle, H. Sawney, T. Junne, L. Dolfini, and K. Tokatlidis A cryptic matrix targeting signal of the yeast ADP/ATP carrier normally inserted by the TIM22 complex is recognized by the TIM23 machinery Biochem. J. 385 2005 173 180
27. S. Vial, H. Lu, S. Allen, P. Savory, D. Thornton, J. Sheehan, and K. Tokatlidis Assembly of Tim9 and Tim10 into a functional chaperone J. Biol. Chem. 277 2002 36100 36108
28. C.M. Koehler, S. Merchant, W. Oppliger, K. Schmid, E. Jarosch, and L. Dolfini Tim9p, an essential partner subunit of Tim10p for the import of mitochondrial carrier proteins EMBO J. 17 1998 6477 6486
29. C.M. Koehler, E. Jarosch, K. Tokatlidis, K. Schmid, R.J. Schweyen, and G. Schatz Import of mitochondrial carriers mediated by essential proteins of the intermembrane space Science 279 1998 369 373
30. A. Adam, M. Endres, C. Sirrenberg, F. Lottspeich, W. Neupert, and M. Brunner Tim9, a new component of the TIM22.54 translocase in mitochondria EMBO J. 18 1999 313 319
31. P. Luciano, S. Vial, M. Vergnolle, S. Dyall, D. Robinson, and K. Tokatlidis Functional reconstitution of the import of the yeast ADP/ATP carrier mediated by the TIM10 complex EMBO J. 20 2001 4099 4106
32. H. Schagger, and G. von Jagow Blue native electrophoresis for isolation of membrane protein complexes in enzymatically active form Anal. Biochem. 199 1991 223 231
33. C.V. Lowry, and R.S. Zitomer Oxygen regulation of anaerobic and aerobic genes mediated by a common factor in yeast Proc. Natl Acad. Sci. USA 81 1984 6129 6133
34. S.P. Curran, D. Leuenberger, E.P. Leverich, D.K. Hwang, K.N. Beverly, and C.M. Koehler The role of Hot13p and redox chemistry in the mitochondrial TIM22 import pathway J. Biol. Chem. 279 2004 43744 43751
35. H. Kadokura, F. Katzen, and J. Beckwith Protein disulfide bond formation in prokaryotes Annu. Rev. Biochem. 72 2003 111 135
36. E. Gross, C.S. Sevier, A. Vala, C.A. Kaiser, and D. Fass A new FAD-binding fold and intersubunit disulfide shuttle in the thiol oxidase Erv2p Nature Struct. Biol. 9 2002 61 67
37. J.F. Collet, and J.C. Bardwell Disulfides out of thin air Nature Struct. Biol. 9 2002 2 3
38. T.G. Senkevich, C.L. White, E.V. Koonin, and B. Moss Complete pathway for protein disulfide bond formation encoded by poxviruses Proc. Natl Acad. Sci. USA 99 2002 6667 6672
39. M. Bader, W. Muse, D.P. Ballou, C. Gassner, and J.C. Bardwell Oxidative protein folding is driven by the electron transport system Cell 98 1999 217 227
40. T. Kobayashi, and K. Ito Respiratory chain strongly oxidizes the CXXC motif of DsbB in the Escherichia coli disulfide bond formation pathway EMBO J. 18 1999 1192 1198