-
1
-
-
6944226431
-
Identification of inhibitors of auxin transcriptional activation by means of chemical genetics in Arabidopsis
-
Armstrong JI, Yuan S, Dale JM, Tanner VN, Theologis A (2004) Identification of inhibitors of auxin transcriptional activation by means of chemical genetics in Arabidopsis. Proc Natl Acad Sci USA 101: 14978-14983
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 14978-14983
-
-
Armstrong, J.I.1
Yuan, S.2
Dale, J.M.3
Tanner, V.N.4
Theologis, A.5
-
3
-
-
11144354973
-
Drug-like annotation and duplicate analysis of a 23-supplier chemical database totalling 2.7 million compounds
-
Baurin N, Baker R, Richardson C, Chen I, Foloppe N, Potter A, Jordan A, Roughley S, Parratt M, Greaney P, et al (2004) Drug-like annotation and duplicate analysis of a 23-supplier chemical database totalling 2.7 million compounds. J Chem Inf Comput Sci 44: 643-651
-
(2004)
J Chem Inf Comput Sci
, vol.44
, pp. 643-651
-
-
Baurin, N.1
Baker, R.2
Richardson, C.3
Chen, I.4
Foloppe, N.5
Potter, A.6
Jordan, A.7
Roughley, S.8
Parratt, M.9
Greaney, P.10
-
4
-
-
0142245637
-
Chemical genetic approaches to plant biology
-
Blackwell HE, Zhao Y (2003) Chemical genetic approaches to plant biology Plant Physiol 133: 448-455
-
(2003)
Plant Physiol
, vol.133
, pp. 448-455
-
-
Blackwell, H.E.1
Zhao, Y.2
-
5
-
-
33845379303
-
Atom pairs as molecular-features in structure activity studies-definition and applications
-
Carhart RE, Smith DH, Venkataraghavan R (1985) Atom pairs as molecular-features in structure activity studies-definition and applications. J Chem Inf Comput Sci 25: 64-73
-
(1985)
J Chem Inf Comput Sci
, vol.25
, pp. 64-73
-
-
Carhart, R.E.1
Smith, D.H.2
Venkataraghavan, R.3
-
6
-
-
0036827080
-
Performance of similarity measures in 2D fragment-based similarity searching: Comparison of structural descriptors and similarity coefficients
-
Chen X, Reynolds CH (2002) Performance of similarity measures in 2D fragment-based similarity searching: comparison of structural descriptors and similarity coefficients. J Chem Inf Comput Sci 42: 1407-1414
-
(2002)
J Chem Inf Comput Sci
, vol.42
, pp. 1407-1414
-
-
Chen, X.1
Reynolds, C.H.2
-
7
-
-
0142244200
-
NIH dives into drug discovery
-
Cousin J (2003) NIH dives into drug discovery. Science 302:218-221
-
(2003)
Science
, vol.302
, pp. 218-221
-
-
Cousin, J.1
-
9
-
-
0034677966
-
Drug discovery: A historical perspective
-
Drews J (2000) Drug discovery: a historical perspective. Science 287: 1960-1964
-
(2000)
Science
, vol.287
, pp. 1960-1964
-
-
Drews, J.1
-
11
-
-
16544364565
-
The Cell Wall Navigator database. A systems-based approach to organism-unrestricted mining of protein families involved in cell wall metabolism
-
Girke T, Lauricha J, Tran H, Keegstra K, Raikhel N (2004) The Cell Wall Navigator database. A systems-based approach to organism-unrestricted mining of protein families involved in cell wall metabolism. Plant Physiol 136: 3003-3008
-
(2004)
Plant Physiol
, vol.136
, pp. 3003-3008
-
-
Girke, T.1
Lauricha, J.2
Tran, H.3
Keegstra, K.4
Raikhel, N.5
-
12
-
-
0344640906
-
Domain-selective small-molecule inhibitor of histone deacetylase 6 (HDAC6)-mediated tubulin deacetylation
-
Haggarty SJ, Koeller KM, Wong JC, Granger CM, Schreiber SL (2003) Domain-selective small-molecule inhibitor of histone deacetylase 6 (HDAC6)-mediated tubulin deacetylation. Proc Natl Acad Sci USA 100: 4389-4394
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 4389-4394
-
-
Haggarty, S.J.1
Koeller, K.M.2
Wong, J.C.3
Granger, C.M.4
Schreiber, S.L.5
-
13
-
-
0036025426
-
Enhanced CACTVS browser of the Open NCI Database
-
Ihlenfeldt WD, Voigt JH, Bienfait B, Oellien F, Nicklaus MC (2002) Enhanced CACTVS browser of the Open NCI Database. J Chem Inf Comput Sci 42: 46-57
-
(2002)
J Chem Inf Comput Sci
, vol.42
, pp. 46-57
-
-
Ihlenfeldt, W.D.1
Voigt, J.H.2
Bienfait, B.3
Oellien, F.4
Nicklaus, M.C.5
-
14
-
-
13844312649
-
ZINC-a free database of commercially available compounds for virtual screening
-
Irwin JJ, Shoichet BK (2005) ZINC-a free database of commercially available compounds for virtual screening. J Chem Inf Comput Sci 45: 177-182
-
(2005)
J Chem Inf Comput Sci
, vol.45
, pp. 177-182
-
-
Irwin, J.J.1
Shoichet, B.K.2
-
15
-
-
11144320699
-
Navigating chemical space for biology and medicine
-
Lipinski C, Hopkins A (2004) Navigating chemical space for biology and medicine. Nature 432: 855-861
-
(2004)
Nature
, vol.432
, pp. 855-861
-
-
Lipinski, C.1
Hopkins, A.2
-
16
-
-
0031024171
-
Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings
-
Lipinski CA, Lombardo F, Dominy BW, Feeney PJ (1997) Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings. Adv Drug Deliv Rev 23: 3-25
-
(1997)
Adv Drug Deliv Rev
, vol.23
, pp. 3-25
-
-
Lipinski, C.A.1
Lombardo, F.2
Dominy, B.W.3
Feeney, P.J.4
-
17
-
-
0036603905
-
Chemical space navigation in lead discovery
-
Oprea TI (2002) Chemical space navigation in lead discovery. Curr Opin Chem Biol 6: 384-389
-
(2002)
Curr Opin Chem Biol
, vol.6
, pp. 384-389
-
-
Oprea, T.I.1
-
18
-
-
0042202919
-
Chemography: The art of navigating in chemical space
-
Oprea TI, Gottfries J (2001) Chemography: the art of navigating in chemical space. J Comb Chem 3: 157-166
-
(2001)
J Comb Chem
, vol.3
, pp. 157-166
-
-
Oprea, T.I.1
Gottfries, J.2
-
19
-
-
3342907009
-
Exploring the chemogenomic knowledge space with annotated chemical libraries
-
Savchuk NP, Balakin KV, Tkachenko SE (2004) Exploring the chemogenomic knowledge space with annotated chemical libraries. Curr Opin Chem Biol 8: 412-417
-
(2004)
Curr Opin Chem Biol
, vol.8
, pp. 412-417
-
-
Savchuk, N.P.1
Balakin, K.V.2
Tkachenko, S.E.3
-
20
-
-
0031710509
-
Chemical genetics resulting from a passion for synthetic organic chemistry
-
Schreiber SL (1998) Chemical genetics resulting from a passion for synthetic organic chemistry. Bioorg Med Chem 6: 1127-1152
-
(1998)
Bioorg Med Chem
, vol.6
, pp. 1127-1152
-
-
Schreiber, S.L.1
-
21
-
-
11144298973
-
Exploring biology with small organic molecules
-
Stockwell BR. (2004) Exploring biology with small organic molecules. Nature 432: 846-854
-
(2004)
Nature
, vol.432
, pp. 846-854
-
-
Stockwell, B.R.1
-
22
-
-
0037432765
-
From knowing to controlling: A path from genomics to drugs using small molecule probes
-
Strausberg RL, Schreiber SL (2003) From knowing to controlling: a path from genomics to drugs using small molecule probes. Science 300: 294-295
-
(2003)
Science
, vol.300
, pp. 294-295
-
-
Strausberg, R.L.1
Schreiber, S.L.2
-
23
-
-
16344363588
-
The power of chemical genomics to study the link between endomembrane system components and the gravitropic response
-
Surpin M, Rojas-Pierce M, Carter C, Hicks G, Vasquez J, Raikhel N (2005) The power of chemical genomics to study the link between endomembrane system components and the gravitropic response. Proc Natl Acad Sci USA 102: 4902-4907
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 4902-4907
-
-
Surpin, M.1
Rojas-Pierce, M.2
Carter, C.3
Hicks, G.4
Vasquez, J.5
Raikhel, N.6
-
24
-
-
0035324932
-
Comparison of the NCI open database with seven large chemical structural databases
-
Voigt JH, Bienfait B, Wang S, Nicklaus MC (2001) Comparison of the NCI open database with seven large chemical structural databases. J Chem Inf Comput Sci 41: 702-712
-
(2001)
J Chem Inf Comput Sci
, vol.41
, pp. 702-712
-
-
Voigt, J.H.1
Bienfait, B.2
Wang, S.3
Nicklaus, M.C.4
-
25
-
-
9344232230
-
Ligand. Info small-molecule Meta-Database
-
von Grotthuss M, Koczyk G, Pas J, Wyrwicz LS, Rychlewski L (2004) Ligand. Info small-molecule Meta-Database. Comb Chem High Throughput Screen 7: 757-761
-
(2004)
Comb Chem High Throughput Screen
, vol.7
, pp. 757-761
-
-
Von Grotthuss, M.1
Koczyk, G.2
Pas, J.3
Wyrwicz, L.S.4
Rychlewski, L.5
-
27
-
-
0042431612
-
SIR1, an upstream component in auxin signaling identified by chemical genetics
-
Zhao Y, Dai X, Blackwell HE, Schreiber SL, Chory J (2003) SIR1, an upstream component in auxin signaling identified by chemical genetics. Science 301: 1107-1110
-
(2003)
Science
, vol.301
, pp. 1107-1110
-
-
Zhao, Y.1
Dai, X.2
Blackwell, H.E.3
Schreiber, S.L.4
Chory, J.5
-
28
-
-
3042552336
-
Sorting inhibitors (Sortins): Chemical compounds to study vacuolar sorting in Arabidopsis
-
Zouhar J, Hicks GR, Raikhel NV (2004) Sorting inhibitors (Sortins): chemical compounds to study vacuolar sorting in Arabidopsis. Proc Natl Acad Sci USA 101: 9497-9501
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 9497-9501
-
-
Zouhar, J.1
Hicks, G.R.2
Raikhel, N.V.3
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