Involvement of α4 integrins in maintenance of cardiac sympathetic axons

Autonomic Neuroscience: Basic and Clinical

Volumn 122, Issue 1-2, 2005, Pages 58-68

  Wingerd, Kevin L ^a   Wayne, William C ^a   Jackson, David Y ^b   Clegg, Dennis O ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b GENENTECH INC   (United States)

Author keywords

Alpha 4; Axon; Beta 1; Hypertensive; Integrins; Myocardial infarction; Neurite outgrowth; Reinnervation; Sprouting; Sympathetic; Synapse; VLA 4

Indexed keywords

ALPHA4 INTEGRIN; ARGINYLGLYCYLASPARTIC ACID; FIBRONECTIN; VASCULAR CELL ADHESION MOLECULE 1; VERY LATE ACTIVATION ANTIGEN 4;

ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; HEART INFARCTION; HEART INNERVATION; NERVE FIBER; NERVE FIBER GROWTH; NERVE SPROUTING; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; RAT; RAT STRAIN; SPONTANEOUSLY HYPERTENSIVE RAT; SYMPATHETIC INNERVATION; SYMPATHETIC NERVE; ADRENERGIC NERVE; ANIMAL; HEART; INNERVATION; METABOLISM; PATHOPHYSIOLOGY;

ADRENERGIC FIBERS; ANIMALS; AXONS; FIBRONECTINS; HEART; INTEGRIN ALPHA4; MYOCARDIAL INFARCTION; RATS; RATS, INBRED SHR; VASCULAR CELL ADHESION MOLECULE-1;

EID: 26944493024     PISSN: 15660702     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.autneu.2005.08.006     Document Type: Article

References (67)

1. P. Altevogt, M. Hubbe, M. Ruppert, J. Lohr, P. von Hoegen, M. Sammar, D.P. Andrew, L. McEvoy, M.J. Humphries, and E.C. Butcher The alpha 4 integrin chain is a ligand for alpha 4 beta 7 and alpha 4 beta 1 J. Exp. Med. 182 1995 345 355
2. A.G. Arroyo, J.T. Yang, H. Rayburn, and R.O. Hynes Differential requirements for alpha4 integrins during fetal and adult hematopoiesis Cell 85 1996 997 1008
3. K.J. Bayless, G.A. Meininger, J.M. Scholtz, and G.E. Davis Osteopontin is a ligand for the alpha4beta1 integrin J. Cell Sci. 111 Pt. 9 1998 1165 1174
4. P.C. Brum, J. Kosek, A. Patterson, D. Bernstein, and B. Kobilka Abnormal cardiac function associated with sympathetic nervous system hyperactivity in mice Am. J. Physiol, Heart Circ. Physiol. 283 2002 H1838 H1845
5. F.R. Burns, S. von Kannen, L. Guy, J.A. Raper, J. Kamholz, and S. Chang DM-GRASP, a novel immunoglobulin superfamily axonal surface protein that supports neurite extension Neuron 7 1991 209 220
6. J.M. Cao, L.S. Chen, B.H. KenKnight, T. Ohara, M.H. Lee, J. Tsai, W.W. Lai, H.S. Karagueuzian, P.L. Wolf, M.C. Fishbein, and P.S. Chen Nerve sprouting and sudden cardiac death Circ. Res. 86 2000 816 821
7. W. Casscells, H. Kimura, J.A. Sanchez, Z.X. Yu, and V.J. Ferrans Immunohistochemical study of fibronectin in experimental myocardial infarction Am. J. Pathol. 137 1990 801 810
8. C.M. Chang, T.J. Wu, S. Zhou, R.N. Doshi, M.H. Lee, T. Ohara, M.C. Fishbein, H.S. Karagueuzian, P.S. Chen, and L.S. Chen Nerve sprouting and sympathetic hyperinnervation in a canine model of atrial fibrillation produced by prolonged right atrial pacing Circulation 103 2001 22 25
9. P.S. Chen, L.S. Chen, J.M. Cao, B. Sharifi, H.S. Karagueuzian, and M.C. Fishbein Sympathetic nerve sprouting, electrical remodeling and the mechanisms of sudden cardiac death Cardiovasc. Res. 50 2001 409 416
10. E.S. Choi, W.J. Rettig, E.A. Wayner, M.L. Srour, and D.O. Clegg Functional identification of integrin laminin receptors that mediate process outgrowth by human SY5Y neuroblastoma cells J. Neurosci. Res. 37 1994 475 488
11. R.A. Clark, J.Q. An, D. Greiling, A. Khan, and J.E. Schwarzbauer Fibroblast migration on fibronectin requires three distinct functional domains J. Invest. Dermatol. 121 2003 695 705
12. D.O. Clegg, K.L. Wingerd, S.T. Hikita, and E.C. Tolhurst Integrins in the development, function and dysfunction of the nervous system Front. Biosci. 8 2003 d723 d750
13. M.L. Condic, and P.C. Letourneau Ligand-induced changes in integrin expression regulate neuronal adhesion and neurite outgrowth Nature 389 1997 852 856
14. B. Culley, J. Murphy, J. Babaie, D. Nguyen, A. Pagel, P. Rousselle, and D.O. Clegg Laminin-5 promotes neurite outgrowth from central and peripheral chick embryonic neurons Neurosci. Lett. 301 2001 83 86
15. M.F. DeFreitas, C.K. Yoshida, W.A. Frazier, D.L. Mendrick, R.M. Kypta, and L.F. Reichardt Identification of integrin alpha 3 beta 1 as a neuronal thrombospondin receptor mediating neurite outgrowth Neuron 15 1995 333 343
16. M.D. Dibner, C. Mytilineou, and I.B. Black Target organ regulation of sympathetic neuron development Brain Res. 123 1977 301 310
17. S.A. Doggrell Moxonidine: some controversy Expert Opin. Pharmacother. 2 2001 337 350
18. X.J. Du, H.S. Cox, A.M. Dart, and M.D. Esler Sympathetic activation triggers ventricular arrhythmias in rat heart with chronic infarction and failure Cardiovasc. Res. 43 1999 919 929
19. P.A. Ekstrom, U. Mayer, A. Panjwani, D. Pountney, J. Pizzey, and D.A. Tonge Involvement of alpha7beta1 integrin in the conditioning-lesion effect on sensory axon regeneration Mol. Cell. Neurosci. 22 2003 383 395
20. C.M. Gall, and G. Lynch Integrins, synaptic plasticity and epileptogenesis Adv. Exp. Med. Biol. 548 2004 12 33
21. M.S. Grotewiel, C.D. Beck, K.H. Wu, X.R. Zhu, and R.L. Davis Integrin-mediated short-term memory in Drosophila Nature 391 1998 455 460
22. J.L. Guan, and R.O. Hynes Lymphoid cells recognize an alternatively spliced segment of fibronectin via the integrin receptor alpha 4 beta 1 Cell 60 1990 53 61
23. S.T. Hikita, G.M. Cann, K.L. Wingerd, L.H. Mullick, W.C. Wayne, S.W. Webb, and D.O. Clegg Integrin alpha4beta1 (VLA-4) expression and activity in retinal and peripheral neurons Mol. Cell. Neurosci. 23 2003 427 439
24. J.P. Himanen, M.J. Chumley, M. Lackmann, C. Li, W.A. Barton, P.D. Jeffrey, C. Vearing, D. Geleick, D.A. Feldheim, A.W. Boyd, M. Henkemeyer, and D.B. Nikolov Repelling class discrimination: ephrin-A5 binds to and activates EphB2 receptor signaling Nat. Neurosci. 7 2004 501 509
25. T. Isobe, T. Hisaoka, A. Shimizu, M. Okuno, S. Aimoto, Y. Takada, Y. Saito, and J. Takagi Propolypeptide of von Willebrand factor is a novel ligand for very late antigen-4 integrin J. Biol. Chem. 272 1997 8447 8453
26. T. Isobe, H. Takahashi, S. Ueki, J. Takagi, and Y. Saito Activity-independent cell adhesion to tissue-type transglutaminase is mediated by alpha4beta1 integrin Eur. J. Cell Biol. 78 1999 876 883
27. D.Y. Jackson Alpha 4 integrin antagonists Curr. Pharm. Des. 8 2002 1229 1253
28. S.H. Kil, C.E. Krull, G. Cann, D. Clegg, and M. Bronner-Fraser The alpha4 subunit of integrin is important for neural crest cell migration Dev. Biol. 202 1998 29 42
29. M. Kitajiri, N. Kubo, K. Tomoda, N. Maeda, T. Yamashita, and T. Kumazawa Sympathetic nerve disturbance and fine structure of adrenergic nerve terminals in nasal mucosa after experimentally-induced nasal hypersensitivity Acta Oto-laryngol., Suppl. 506 1993 47 50
30. M. Kondo, M. Terada, T. Fujiwara, N. Arita, A. Yano, and R. Tabei Noradrenergic hyperinnervation in the heart of stroke-prone spontaneously hypertensive rats Clin. Exp. Pharmacol. Physiol. Suppl. 22 1995 S75 S76
31. K. Kullander, and R. Klein Mechanisms and functions of Eph and ephrin signalling Nat. Rev., Mol. Cell Biol. 3 2002 475 486
32. S.C. Landis Rat sympathetic neurons and cardiac myocytes developing in microcultures: correlation of the fine structure of endings with neurotransmitter function in single neurons Proc. Natl. Acad. Sci. U. S. A. 73 1976 4220 4224
33. M.L. Lindsey, D.L. Mann, M.L. Entman, and F.G. Spinale Extracellular matrix remodeling following myocardial injury Ann. Med. 35 2003 316 326
34. J.A. Lipp, and A.M. Rudolph Sympathetic nerve development in the rat and guinea-pig heart Biol. Neonate 21 1972 76 82
35. R.R. Lobb, and M.E. Hemler The pathophysiologic role of alpha 4 integrins in vivo J. Clin. Invest. 94 1994 1722 1728
36. S.E. Luff Ultrastructure of sympathetic axons and their structural relationship with vascular smooth muscle Anat. Embryol. (Berl.) 193 1996 515 531
37. A.P. Mould, and M.J. Humphries Identification of a novel recognition sequence for the integrin alpha 4 beta 1 in the COOH-terminal heparin-binding domain of fibronectin EMBO J. 10 1991 4089 4095
38. J. Nawata, I. Ohno, S. Isoyama, J. Suzuki, S. Miura, J. Ikeda, and K. Shirato Differential expression of alpha 1, alpha 3 and alpha 5 integrin subunits in acute and chronic stages of myocardial infarction in rats Cardiovasc. Res. 43 1999 371 381
39. S.L. Nori, M. Gaudino, F. Alessandrini, E. Bronzetti, and P. Santarelli Immunohistochemical evidence for sympathetic denervation and reinnervation after necrotic injury in rat myocardium Cell. Mol. Biol. (Noisy-le-grand) 41 1995 799 807
40. L. Osborn, C. Hession, R. Tizard, C. Vassallo, S. Luhowskyj, G. Chi-Rosso, and R. Lobb Direct expression cloning of vascular cell adhesion molecule 1, a cytokine-induced endothelial protein that binds to lymphocytes Cell 59 1989 1203 1211
41. P. Palatini, and S. Julius Relevance of heart rate as a risk factor in hypertension Curr. Hypertens. Rep. 1 1999 219 224
42. P.J. Podrid, T. Fuchs, and R. Candinas Role of the sympathetic nervous system in the genesis of ventricular arrhythmia Circulation 82 1990 I103 I113
43. M.K. Pugsley, M.J. Walker, and S.L. Yong Are the arrhythmias due to myocardial ischaemia and infarction dependent upon the sympathetic system? Cardiovasc. Res. 43 1999 830 831
44. D. Purves, and J.W. Lichtman Synaptic sites on reinnervated nerve cells visualized at two different times in living mice J. Neurosci. 7 1987 1492 1497
45. J. Rohrbough, M.S. Grotewiel, R.L. Davis, and K. Broadie Integrin-mediated regulation of synaptic morphology, transmission, and plasticity J. Neurosci. 20 2000 6868 6878
46. M.S. Rumantir, G.L. Jennings, G.W. Lambert, D.M. Kaye, D.R. Seals, and M.D. Esler The 'adrenaline hypothesis' of hypertension revisited: evidence for adrenaline release from the heart of patients with essential hypertension J. Hypertens. 18 2000 717 723
47. M.P. Schlaich, D.M. Kaye, E. Lambert, M. Sommerville, F. Socratous, and M.D. Esler Relation between cardiac sympathetic activity and hypertensive left ventricular hypertrophy Circulation 108 2003 560 565
48. P.J. Schwartz, M. Stramba-Badiale, A. Segantini, P. Austoni, G. Bosi, R. Giorgetti, F. Grancini, E.D. Marni, F. Perticone, D. Rosti, and P. Salice Prolongation of the QT interval and the sudden infant death syndrome N. Engl. J. Med. 338 1998 1709 1714
49. A.M. Sheppard, M.D. Onken, G.D. Rosen, P.G. Noakes, and D.C. Dean Expanding roles for alpha 4 integrin and its ligands in development Cell Adhes. Commun. 2 1994 27 43
50. M.C. Siebers, P.J. Ter Brugge, X.F. Walboomers, and J.A. Jansen Integrins as linker proteins between osteoblasts and bone replacing materials. A critical review Biomaterials 26 2005 137 146
51. B.Z. Simkhovich, P. Marjoram, C. Poizat, L. Kedes, and R.A. Kloner Age-related changes of cardiac gene expression following myocardial ischemia/reperfusion Arch. Biochem. Biophys. 420 2003 268 278
52. F.A. Spring, S.F. Parsons, S. Ortlepp, M.L. Olsson, R. Sessions, R.L. Brady, and D.J. Anstee Intercellular adhesion molecule-4 binds alpha(4)beta(1) and alpha(V)-family integrins through novel integrin-binding mechanisms Blood 98 2001 458 466
53. M.S. Stanton, M.M. Tuli, N.L. Radtke, J.J. Heger, W.M. Miles, B.H. Mock, R.W. Burt, H.N. Wellman, and D.P. Zipes Regional sympathetic denervation after myocardial infarction in humans detected noninvasively using I-123-metaiodobenzylguanidine J. Am. Coll. Cardiol. 14 1989 1519 1526
54. M. Sun, M.A. Opavsky, D.J. Stewart, M. Rabinovitch, F. Dawood, W.H. Wen, and P.P. Liu Temporal response and localization of integrins beta1 and beta3 in the heart after myocardial infarction: regulation by cytokines Circulation 107 2003 1046 1052
55. R. Tabei, M. Kondo, M. Terada, T. Miyazaki, Y. Watanabe, D. Shimizu, and I. Yamamoto Noradrenergic hyperinnervation in the caval vein of stroke-prone spontaneously hypertensive rats Clin. Exp. Pharmacol. Physiol. Suppl. 22 1995 S73 S74
56. D.C. Turner, L.A. Flier, and S. Carbonetto Identification of a cell-surface protein involved in PC12 cell-substratum adhesion and neurite outgrowth on laminin and collagen J. Neurosci. 9 1989 3287 3296
57. M.G. Vogelezang, Z. Liu, J.B. Relvas, G. Raivich, S.S. Scherer, and C. ffrench-Constant Alpha4 integrin is expressed during peripheral nerve regeneration and enhances neurite outgrowth J. Neurosci. 21 2001 6732 6744
58. R. Vracko, D. Thorning, and R.G. Frederickson Fate of nerve fibers in necrotic, healing, and healed rat myocardium Lab. Invest. 63 1990 490 501
59. R. Vracko, D. Thorning, and R.G. Frederickson Nerve fibers in human myocardial scars Hum. Pathol. 22 1991 138 146
60. W. Wallquist, J. Zelano, S. Plantman, S.J. Kaufman, S. Cullheim, and H. Hammarberg Dorsal root ganglion neurons up-regulate the expression of laminin-associated integrins after peripheral but not central axotomy J. Comp. Neurol. 480 2004 162 169
61. I.E. Willems, J.W. Arends, and M.J. Daemen Tenascin and fibronectin expression in healing human myocardial scars J. Pathol. 179 1996 321 325
62. K.L. Wingerd, N.L. Goodman, J.W. Tresser, M.M. Smail, S.T. Leu, S.J. Rohan, J.L. Pring, D.Y. Jackson, and D.O. Clegg Alpha 4 integrins and vascular cell adhesion molecule-1 play a role in sympathetic innervation of the heart J. Neurosci. 22 2002 10772 10780
63. K.L. Wingerd, N.L. Goodman, S.T. Leu, and D.O. Clegg Expression and function of integrin alpha4beta1 and vascular cell adhesion molecule-1 (VCAM-1) during sympathetic innervation of the heart Dev. Dyn. 231 2004 359 369
64. R. Yabkowitz, V.M. Dixit, N. Guo, D.D. Roberts, and Y. Shimizu Activated T-cell adhesion to thrombospondin is mediated by the alpha 4 beta 1 (VLA-4) and alpha 5 beta 1 (VLA-5) integrins J. Immunol. 151 1993 149 158
65. S. Zhou, L.S. Chen, Y. Miyauchi, M. Miyauchi, S. Kar, S. Kangavari, M.C. Fishbein, B. Sharifi, and P.S. Chen Mechanisms of cardiac nerve sprouting after myocardial infarction in dogs Circ. Res. 95 2004 76 83
66. D.P. Zipes Influence of myocardial ischemia and infarction on autonomic innervation of heart Circulation 82 1990 1095 1105
67. J.X. Zou, B. Wang, M.S. Kalo, A.H. Zisch, E.B. Pasquale, and E. Ruoslahti An Eph receptor regulates integrin activity through R-Ras Proc. Natl. Acad. Sci. U. S. A. 96 1999 13813 13818