Repeated quinpirole treatment increases cAMP-dependent protein kinase activity and CREB phosphorylation in nucleus accumbens and reverses quinpirole-induced sensorimotor gating deficits in rats

Neuropsychopharmacology

Volumn 29, Issue 10, 2004, Pages 1823-1830

  Culm, Kerry E ^a   Lugo Escobar, Natasha ^a   Hope, Bruce T ^b   Hammer Jr , Ronald P ^a,c  

^a TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b NATIONAL INSTITUTE ON DRUG ABUSE   (United States)

^c TUFTS MEDICAL CENTER   (United States)

Author keywords

D2 like receptors; Nucleus accumbens; Phospho CREB; PKA; Prepulse inhibition; Schizophrenia

Indexed keywords

3 ALLYL 6 CHLORO 2,3,4,5 TETRAHYDRO 7,8 DIHYDROXY 1 PHENYL 1H 3 BENZAZEPINE; ADENYLATE CYCLASE; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; FORSKOLIN; QUINPIROLE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CHANNEL GATING; CONTROLLED STUDY; DRUG DOSE REGIMEN; ENZYME ACTIVATION; ENZYME ACTIVITY; MALE; NONHUMAN; NUCLEUS ACCUMBENS; PREPULSE INHIBITION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; SCHIZOPHRENIA; SENSORIMOTOR FUNCTION; STARTLE REFLEX;

ACOUSTIC STIMULATION; ADENYLATE CYCLASE; ANIMALS; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; CYCLIC AMP-DEPENDENT PROTEIN KINASES; DOPAMINE ANTAGONISTS; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME ACTIVATORS; IMMUNOHISTOCHEMISTRY; MALE; NUCLEUS ACCUMBENS; PHOSPHORYLATION; QUINPIROLE; RATS; RATS, SPRAGUE-DAWLEY; STARTLE REACTION;

EID: 5044227976     PISSN: 0893133X     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.npp.1300483     Document Type: Article

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