Inactivation of p53 sensitizes astrocytic glioma cells to BCNU and temozolomide, but not cisplatin

Journal of Neuro-Oncology

Volumn 74, Issue 2, 2005, Pages 141-149

  Xu, G Wei ^a,b   Mymryk, Joe S ^a,b   Cairncross, J Gregory ^a,c,d  

^a UNIVERSITY OF WESTERN ONTARIO   (Canada)

^b LONDON REGIONAL CANCER PROGRAM   (Canada)

^c UNIVERSITY OF CALGARY   (Canada)

^d FOOTHILLS HOSPITAL   (Canada)

Author keywords

BCNU; Cellcycle; Chemotherapy; Glioma; p21WAF1; p53; TMZ

Indexed keywords

CARMUSTINE; CISPLATIN; CYCLIN DEPENDENT KINASE INHIBITOR 1; PROTEIN P53; TEMOZOLOMIDE;

ANTINEOPLASTIC ACTIVITY; ARTICLE; ASTROCYTE; ASTROCYTOMA; CELL CYCLE G2 PHASE; CELL DEATH; CELL SURVIVAL; CHEMOSENSITIVITY; CLONOGENESIS; CONTROLLED STUDY; GLIOMA; GLIOMA CELL; HUMAN; HUMAN CELL; PROTEIN FUNCTION; TUMOR CELL CULTURE; WESTERN BLOTTING;

ANTINEOPLASTIC AGENTS; ASTROCYTOMA; BLOTTING, WESTERN; CARMUSTINE; CELL CYCLE; CISPLATIN; CYCLIN-DEPENDENT KINASE INHIBITOR P21; DACARBAZINE; GENE SILENCING; HUMANS; TUMOR CELLS, CULTURED; TUMOR STEM CELL ASSAY; TUMOR SUPPRESSOR PROTEIN P53;

EID: 26944481466     PISSN: 0167594X     EISSN: 15737373     Source Type: Journal    
DOI: 10.1007/s11060-004-6601-3     Document Type: Article

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