Animal models for the study of myocardial protection against ischemia

Drug Discovery Today: Disease Models

Volumn 2, Issue 3, 2005, Pages 219-225

  Philipp, Sebastian ^a   Cohen, Michael V ^a   Downey, James M ^a  

^a UNIVERSITY OF SOUTH ALABAMA COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CALCIUM; HYPOXANTHINE; OXYGEN; REACTIVE OXYGEN METABOLITE; URIC ACID; XANTHINE OXIDASE;

ACUTE HEART INFARCTION; CARDIOVASCULAR RISK; COLLATERAL CIRCULATION; CORONARY ARTERY OBSTRUCTION; DISEASE SEVERITY; DRUG ACTIVITY; EX VIVO STUDY; HEART FAILURE; HEART FUNCTION; HEART INFARCTION SIZE; HEART MUSCLE BLOOD FLOW; HEART MUSCLE CELL; HEART MUSCLE CONTRACTILITY; HEART MUSCLE ISCHEMIA; HEART MUSCLE REPERFUSION; HEART PROTECTION; HUMAN; IN VITRO STUDY; IN VIVO STUDY; NONHUMAN; OXYGEN CONSUMPTION; OXYGEN SUPPLY; REOXYGENATION; REPERFUSION INJURY; REVIEW; RISK ASSESSMENT; RISK FACTOR;

EID: 26944458852     PISSN: 17406757     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ddmod.2005.08.006     Document Type: Review

References (59)

1. J.M. Pfeffer et al. Progressive ventricular remodeling in rat with myocardial infarction Am. J. Physiol. 260 1991 H1406-H1414
2. M. St. John Sutton et al. Cardiovascular death and left ventricular remodeling two years after myocardial infarction. Baseline predictors and impact of long-term use of captopril: Information from the Survival and Ventricular Enlargement (SAVE) trial Circulation 96 1997 3294-3299
3. W. Schaper and B. Winkler Of mice and men - the future of cardiovascular research in the molecular era Cardiovasc. Res. 39 1998 3-7
4. P. Verdouw et al. Animal models in the study of myocardial ischaemia and ischaemic syndromes Cardiovasc. Res. 39 1998 121-135
5. X. Zhai et al. Preconditioning and post-ischaemic contractile dysfunction: The role of impaired oxygen delivery vs extracellular metabolite accumulation J. Mol. Cell Cardiol. 25 1993 847-857
6. A.C. Cave and D.J. Hearse Ischaemic preconditioning and contractile function: Studies with normothermic and hypothermic global ischaemia J. Mol. Cell Cardiol. 24 1992 1113-1123
7. P.R. Maroko et al. Factors influencing infarct size following experimental coronary artery occlusions Circulation 43 1971 67-82
8. K.A. Reimer et al. Reduction by propranolol of myocardial necrosis following temporary coronary artery occlusion in dogs Circ. Res. 33 1973 353-363
9. R. Bolli Mechanism of myocardial "stunning" Circulation 82 1990 723-738
10. A.M. Vogt et al. Intramyocardial infusion of tool drugs for the study of molecular mechanisms in ischemic preconditioning Basic Res. Cardiol. 91 1996 389-400
11. K. Ytrehus et al. Rat and rabbit heart infarction: Effects of anesthesia, perfusate, risk zone, and method of infarct sizing Am. J. Physiol. 267 1994 H2383-H2390
12. W. Schaper Experimental infarcts and the microcirculation (D.J. Hearse and D.M. Yellon eds.) In Therapeutic Approaches to Myocardial Infarct Size Limitation 1984 Raven Press 79-90
13. K.A. Reimer et al. The wavefront phenomenon of ischemic cell death. 1. Myocardial infarct size vs. duration of coronary occlusion in dogs Circulation 56 1977 786-794
14. P. Libby et al. Effect of practolol on the extent of myocardial ischaemic injury after experimental coronary occlusion and its effects on ventricular function in the normal and ischaemic heart Cardiovasc. Res. 7 1973 167-173
15. Y-T. Shen et al. Innate protection of baboon myocardium: Effects of coronary artery occlusion and reperfusion Am. J. Physiol. 270 1996 H1812-H1818
16. K.A. Reimer and R.B. Jennings The "wavefront phenomenon"; of myocardial ischemic cell death. II. Transmural progression of necrosis within the framework of ischemic bed size (myocardium at risk) and collateral flow Lab. Invest. 40 1979 633-644
17. R. Schulz et al. Involvement of activation of ATP-dependent potassium channels in ischemic preconditioning in swine Am. J. Physiol. 267 1994 H1341-H1352
18. M.L. Charlat et al. Evidence for a pathogenetic role of xanthine oxidase in the "stunned" myocardium Am. J. Physiol. 252 1987 H566-H577 H577
19. R. Bolli et al. Marked reduction of free radical generation and contractile dysfunction by antioxidant therapy begun at the time of reperfusion: Evidence that myocardial "stunning"; is a manifestation of reperfusion injury Circ. Res. 65 1989 607-622
20. J.M. Downey et al. Xanthine oxidase is not a source of free radicals in the ischemic rabbit heart J. Mol. Cell Cardiol. 19 1987 1053-1060
21. L.J. Eddy et al. Free radical-producing enzyme, xanthine oxidase, is undetectable in human hearts Am. J. Physiol. 253 1987 H709-H711
22. 1 selective agonists offer minimal protection against ischaemic injury to isolated rat cardiomyocytes Cardiovasc. Res. 27 1993 1670-1676
23. Y. Li and R.A. Kloner The cardioprotective effects of ischemic "preconditioning" are not mediated by adenosine receptors in rat hearts Circulation 87 1993 1642-1648
24. G.K. Asimakis et al. Attenuation of postischaemic dysfunction by ischaemic preconditioning is not mediated by adenosine in the isolated rat heart Cardiovasc. Res. 27 1993 1522-1530
25. R.J. Gelpi et al. Xanthine oxidase contributes to preconditioning's preservation of left ventricular developed pressure in isolated rat heart: Developed pressure may not be an appropriate end-point for studies of preconditioning Basic Res. Cardiol. 97 2002 40-46
26. 1 adenosine receptors in rabbit heart Circulation 84 1991 350-356
27. T. Miura et al. Progression of myocardial infarction in a collateral flow deficient species Jpn. Heart J. 30 1989 695-708
28. Y. Birnbaum et al. Differences in reperfusion length following 30 minutes of ischemia in the rabbit influence infarct size, as measured by triphenyltetrazolium chloride staining J. Mol. Cell Cardiol. 29 1997 657-666
29. C. Nienaber et al. The relationship between the perfusion deficit, infarct size and time after experimental coronary artery occlusion Basic Res. Cardiol. 78 1983 210-226
30. Z-Q. Zhao et al. Dynamic progression of contractile and endothelial dysfunction and infarct extension in the late phase of reperfusion J. Surg. Res. 94 2000 133-144
31. M.R. Litt et al. Neutrophil depletion limited to reperfusion reduces myocardial infarct size after 90 minutes of ischemia: Evidence for neutrophil-mediated reperfusion injury Circulation 80 1989 1816-1827
32. B.R. Reddy et al. Pretreatment with the iron chelator desferrioxamine fails to provide sustained protection against myocardial ischaemia-reperfusion injury Cardiovasc. Res. 25 1991 711-718
33. C. Shirato et al. Tetrazolium artifactually indicates superoxide dismutase-induced salvage in reperfused rabbit heart J. Mol. Cell Cardiol. 21 1989 1187-1193
34. S.C. Armstrong et al. Comparison of in vitro preconditioning responses of isolated pig and rabbit cardiomyocytes: Effects of a protein phosphatase inhibitor, fostriecin J. Mol. Cell Cardiol. 29 1997 3009-3024
35. ATP channels Circ. Res. 84 1999 1396-1400
36. 2-purinoceptor activation stimulates phosphoinositide hydrolysis and inhibits accumulation of cAMP in cultured ventricular myocytes Circ. Res. 70 1992 477-485
37. L.A. Gomez et al. Use of the MTT assay in adult ventricular cardiomyocytes to assess viability: Effects of adenosine and potassium on cellular survival J. Mol. Cell Cardiol. 29 1997 1255-1266
38. J.S. Mitcheson et al. Cultured adult cardiac myocytes: Future applications, culture methods, morphological and electrophysiological properties Cardiovasc. Res. 39 1998 280-300
39. S.C. Armstrong et al. Preconditioning of isolated rabbit cardiomyocytes: no evident separation of induction, memory and protection J. Mol. Cell Cardiol. 29 1997 2285-2298
40. D.J. Hausenloy et al. Ischemic preconditioning protects by activating prosurvival kinases at reperfusion Am. J. Physiol. 288 2005 H971-H976
41. D.J. Hausenloy et al. Preconditioning protects by inhibiting mitochondrial permeability transition Am. J. Physiol. 287 2004 H841-H849
42. C.P. Baines et al. Loss of cyclophilin D reveals a critical role for mitochondrial permeability transition in cell death Nature 434 2005 658-662
43. S. Armstrong et al. Preconditioning of isolated rabbit cardiomyocytes: induction by metabolic stress and blockade by the adenosine antagonist SPT and calphostin C, a protein kinase C inhibitor Cardiovasc. Res. 28 1994 72-77
44. S. Armstrong et al. C.E. Ganote In vitro ischaemic preconditioning of isolated rabbit cardiomyocytes: Effects of selective adenosine receptor blockade and calphostin C Cardiovasc. Res. 29 1995 647-652
45. S. Armstrong and C.E. Ganote Preconditioning of isolated rabbit cardiomyocytes: Effects of glycolytic blockade, phorbol esters, and ischaemia Cardiovasc. Res. 28 1994 1700-1706
46. J.S. Ikonomidis et al. Preconditioning cultured human pediatric myocytes requires adenosine and protein kinase C Am. J. Physiol. 272 1997 H1220-H1230
47. R.A. Gottlieb et al. Preconditioning in rabbit cardiomyocytes: Role of pH, vacuolar proton ATPase, and apoptosis J. Clin. Invest. 97 1996 2391-2398
48. T.L. Vanden Hoek et al. Reactive oxygen species released from mitochondria during brief hypoxia induce preconditioning in cardiomyocytes J. Biol. Chem. 273 1998 18092-18098
49. T. Shirai et al. Preconditioning human cardiomyocytes and endothelial cells J. Thorac. Cardiovasc. Surg. 115 1998 210-219
50. T.L. Vanden Hoek et al. Preconditioning in cardiomyocytes protects by attenuating oxidant stress at reperfusion Circ. Res. 86 2000 541-548
51. J. Duranteau et al. Intracellular signaling by reactive oxygen species during hypoxia in cardiomyocytes J. Biol. Chem. 273 1998 11619-11624
52. B. Siegmund et al. Halothane protects cardiomyocytes against reoxygenation-induced hypercontracture Circulation 96 1997 4372-4379
53. R.A. Gottlieb et al. Reperfusion injury induces apoptosis in rabbit cardiomyocytes J. Clin. Invest. 94 1994 1621-1628
54. T. Uchiyama et al. Role of Akt signaling in mitochondrial survival pathway triggered by hypoxic preconditioning Circulation 109 2004 3042-3049
55. M. Juhaszova et al. Glycogen synthase kinase-3β mediates convergence of protection signaling to inhibit the mitochondrial permeability transition pore J. Clin. Invest. 113 2004 1535-1549
56. Z. Xu et al. Adenosine produces nitric oxide and prevents mitochondrial oxidant damage in rat cardiomyocytes Cardiovasc. Res. 65 2005 803-812
57. M. Akao et al. Antiapoptotic effect of nicorandil mediated by mitochondrial ATP-sensitive potassium channels in cultured cardiac myocytes J. Am. Coll. Cardiol. 40 2002 803-810
58. D.J. Hausenloy and D.M. Yellon The mitochondrial permeability transition pore: Its fundamental role in mediating cell death during ischaemia and reperfusion J. Mol. Cell Cardiol. 35 2003 339-341
59. 2+-induced mitochondrial permeability transition Cardiovasc. Res. 61 2004 115-122