메뉴 건너뛰기




Volumn 32, Issue 9, 2005, Pages 728-734

Mechanisms underlying relaxation of rabbit aorta by BAY 41-2272, a nitric oxide-independent soluble guanylate cyclase activator

Author keywords

1H 1,2,4 oxadiazolo 4,3 a quinoxalin 1 one; Aorta; BAY 41 2272; Nitric oxide; Sildenafil; Soluble guanylate cyclase

Indexed keywords

(5 CYCLOPROPYL 2 [1 (2 FLUORO BENZYL) 1H PYRAZOLO[3,4 B]PYRIDIN 3 YL] PYRIMIDIN 4 YLAMINE); 1H [1,2,4]OXADAZOLO[4,3 A]QUINOXALIN 1 ONE; 4 AMINO 5 CYCLOPROPYL 2 [1 (2 FLUOROBENZYL) 1H PYRAZOLO[3,4 B]PYRIDIN 3 YL]PYRIMIDINE; ACETYLCHOLINE; GUANYLATE CYCLASE ACTIVATOR; GUANYLATE CYCLASE INHIBITOR; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; PHENOBARBITAL; SILDENAFIL; UNCLASSIFIED DRUG; 1H (1,2,3)OXADIAZOLO(4,4 A)QUINOXALIN 1 ONE; 1H-(1,2,3)OXADIAZOLO(4,4-A)QUINOXALIN-1-ONE; 3 (4 AMINO 5 CYCLOPROPYLPYRIMIDINE 2 YL) 1 (2 FLUOROBENZYL) 1H PYRAZOLO(3,4 B)PYRIDINE; 3-(4-AMINO-5-CYCLOPROPYLPYRIMIDINE-2-YL)-1-(2-FLUOROBENZYL)-1H-PYRAZOLO(3,4-B)PYRIDINE; GUANYLATE CYCLASE; OXADIAZOLE DERIVATIVE; PIPERAZINE DERIVATIVE; PYRAZOLE DERIVATIVE; PYRIDINE DERIVATIVE; QUINOXALINE DERIVATIVE;

EID: 26944451367     PISSN: 03051870     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1440-1681.2005.04262.x     Document Type: Article
Times cited : (37)

References (41)
  • 1
    • 0026068870 scopus 로고
    • Development and mechanism of a specific supersensitivity to nitrovasodilators after inhibition of vascular nitric oxide synthesis in vivo
    • Moncada S, Rees DD, Schulz R et al. Development and mechanism of a specific supersensitivity to nitrovasodilators after inhibition of vascular nitric oxide synthesis in vivo. Proc. Natl Acad. Sci. USA 1991; 88: 2166-70.
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 2166-2170
    • Moncada, S.1    Rees, D.D.2    Schulz, R.3
  • 2
    • 0025081992 scopus 로고
    • Nitric oxide and cyclic GMP formation upon electrical field stimulation cause relaxation of corpus cavernosum smooth muscle
    • Ignarro LJ, Bush PA, Buga GM et al. Nitric oxide and cyclic GMP formation upon electrical field stimulation cause relaxation of corpus cavernosum smooth muscle. Biochem. Biophys. Res. Commun. 1990; 170: 843-50.
    • (1990) Biochem. Biophys. Res. Commun. , vol.170 , pp. 843-850
    • Ignarro, L.J.1    Bush, P.A.2    Buga, G.M.3
  • 3
    • 0033832073 scopus 로고    scopus 로고
    • Guanylate cyclases and signaling by cyclic GMP
    • Lucas KA, Pitari GM, Kazerounian S et al. Guanylate cyclases and signaling by cyclic GMP. Pharmacol. Rev. 2000; 52: 375-414.
    • (2000) Pharmacol. Rev. , vol.52 , pp. 375-414
    • Lucas, K.A.1    Pitari, G.M.2    Kazerounian, S.3
  • 4
    • 0034033975 scopus 로고    scopus 로고
    • Rising behind NO: cGMP-dependent protein kinases
    • Hofmann F, Ammendola A, Schlossmann J. Rising behind NO: cGMP-dependent protein kinases. J. Cell Sci. 2000; 113: 1671-6.
    • (2000) J. Cell Sci. , vol.113 , pp. 1671-1676
    • Hofmann, F.1    Ammendola, A.2    Schlossmann, J.3
  • 5
    • 0032615901 scopus 로고    scopus 로고
    • Cyclic GMP as substrate and regulator of cyclic nucleotide phosphodiesterases (PDEs)
    • Juilfs DM, Soderling S, Burns F et al. Cyclic GMP as substrate and regulator of cyclic nucleotide phosphodiesterases (PDEs). Rev. Physiol. Biochem. Pharmacol. 1999; 135: 67-104.
    • (1999) Rev. Physiol. Biochem. Pharmacol. , vol.135 , pp. 67-104
    • Juilfs, D.M.1    Soderling, S.2    Burns, F.3
  • 6
    • 0034115825 scopus 로고    scopus 로고
    • The new British Hypertension Society guidelines: A view from primary care
    • Hobbs FD. The new British Hypertension Society guidelines: A view from primary care. J. Hum. Hypertens. 2000; 14: 223-5.
    • (2000) J. Hum. Hypertens. , vol.14 , pp. 223-225
    • Hobbs, F.D.1
  • 7
    • 0031866842 scopus 로고    scopus 로고
    • The use of nitric oxide donors in pharmacological studies
    • Feelisch M. The use of nitric oxide donors in pharmacological studies. Naunyn Schmiedebergs Arch. Pharmacol. 1998; 358: 113-22.
    • (1998) Naunyn Schmiedebergs Arch. Pharmacol. , vol.358 , pp. 113-122
    • Feelisch, M.1
  • 8
    • 0028109332 scopus 로고
    • YC-1, a novel activator of platelet guanylate cyclase
    • Ko FN, Wu CC, Kuo SC et al. YC-1, a novel activator of platelet guanylate cyclase. Blood 1994; 84: 4226-33.
    • (1994) Blood , vol.84 , pp. 4226-4233
    • Ko, F.N.1    Wu, C.C.2    Kuo, S.C.3
  • 9
    • 0029166002 scopus 로고
    • YC-1 inhibited human platelet aggregation through NO-independent activation of soluble guanylate cyclase
    • Wu CC, Ko FN, Kuo SC et al. YC-1 inhibited human platelet aggregation through NO-independent activation of soluble guanylate cyclase. Br. J. Pharmacol. 1995; 116: 1973-8.
    • (1995) Br. J. Pharmacol. , vol.116 , pp. 1973-1978
    • Wu, C.C.1    Ko, F.N.2    Kuo, S.C.3
  • 10
    • 0030476908 scopus 로고    scopus 로고
    • Sensitizing soluble guanylate cyclase to become a highly CO-sensitive enzyme
    • Friebe A, Schultz G, Koesling D. Sensitizing soluble guanylate cyclase to become a highly CO-sensitive enzyme. EMBO J. 1996; 15: 6863-8.
    • (1996) EMBO J. , vol.15 , pp. 6863-6868
    • Friebe, A.1    Schultz, G.2    Koesling, D.3
  • 11
    • 0031046943 scopus 로고    scopus 로고
    • Effect of YC-1, an NO-independent, superoxide-sensitive stimulator of soluble guanylate cyclase, on smooth muscle responsiveness to nitrovasodilators
    • Mulsch A, Bauersachs J, Schafer A et al. Effect of YC-1, an NO-independent, superoxide-sensitive stimulator of soluble guanylate cyclase, on smooth muscle responsiveness to nitrovasodilators. Br. J. Pharmacol. 1997; 120: 681-9.
    • (1997) Br. J. Pharmacol. , vol.120 , pp. 681-689
    • Mulsch, A.1    Bauersachs, J.2    Schafer, A.3
  • 12
    • 0033016797 scopus 로고    scopus 로고
    • Purified soluble guanylate cyclase expressed in a baculovirus/Sf9 system: Stimulation by YC-1, nitric oxide, and carbon monoxide
    • Hoenicka M, Becker EM, Apeler H et al. Purified soluble guanylate cyclase expressed in a baculovirus/Sf9 system: Stimulation by YC-1, nitric oxide, and carbon monoxide. J. Mol. Med. 1999; 77: 14-23.
    • (1999) J. Mol. Med. , vol.77 , pp. 14-23
    • Hoenicka, M.1    Becker, E.M.2    Apeler, H.3
  • 13
    • 0035826261 scopus 로고    scopus 로고
    • NO-independent regulatory site on soluble guanylate cyclase
    • Stasch JP, Becker EM, Alonso-Alija C et al. NO-independent regulatory site on soluble guanylate cyclase. Nature 2001; 410: 212-15.
    • (2001) Nature , vol.410 , pp. 212-215
    • Stasch, J.P.1    Becker, E.M.2    Alonso-Alija, C.3
  • 14
    • 2642541002 scopus 로고    scopus 로고
    • NO-independent regulatory site of direct sGC stimulators like YC-1 and BAY 41-2272
    • Becker EM, Alonso-Alija C, Apeler H et al. NO-independent regulatory site of direct sGC stimulators like YC-1 and BAY 41-2272. BMC Pharmacol. 2001; 1: 13-24.
    • (2001) BMC Pharmacol. , vol.1 , pp. 13-24
    • Becker, E.M.1    Alonso-Alija, C.2    Apeler, H.3
  • 16
    • 0037432180 scopus 로고    scopus 로고
    • Cardiorenal and humoral properties of a novel direct soluble guanylate cyclase stimulator BAY 41-2272 in experimental congestive heart failure
    • Boerrigter G, Costello-Boerrigter LC, Cataliotti A et al. Cardiorenal and humoral properties of a novel direct soluble guanylate cyclase stimulator BAY 41-2272 in experimental congestive heart failure. Circulation 2003; 107: 686-9.
    • (2003) Circulation , vol.107 , pp. 686-689
    • Boerrigter, G.1    Costello-Boerrigter, L.C.2    Cataliotti, A.3
  • 17
    • 0346643472 scopus 로고    scopus 로고
    • Effects of the soluble guanylyl cyclase activator, YC-1, on vascular tone, cyclic GMP levels and phosphodiesterase activity
    • Galle J, Zabel U, Hubner U et al. Effects of the soluble guanylyl cyclase activator, YC-1, on vascular tone, cyclic GMP levels and phosphodiesterase activity. Br. J. Pharmacol. 1999; 127: 195-203.
    • (1999) Br. J. Pharmacol. , vol.127 , pp. 195-203
    • Galle, J.1    Zabel, U.2    Hubner, U.3
  • 18
    • 0035987790 scopus 로고    scopus 로고
    • NO- and haem-independent activation of soluble guanylyl cyclase: Molecular basis and cardiovascular implications of a new pharmacological principle
    • Stasch JP, Schmidt P, Alonso-Alija C et al. NO- and haem-independent activation of soluble guanylyl cyclase: Molecular basis and cardiovascular implications of a new pharmacological principle. Br. J. Pharmacol. 2002; 136: 773-83.
    • (2002) Br. J. Pharmacol. , vol.136 , pp. 773-783
    • Stasch, J.P.1    Schmidt, P.2    Alonso-Alija, C.3
  • 19
    • 0032734962 scopus 로고    scopus 로고
    • Release of nitric oxide from endothelial cells stimulated by YC-1, an activator of soluble guanylate cyclase
    • Wohlfart P, Malinski T, Ruetten H et al. Release of nitric oxide from endothelial cells stimulated by YC-1, an activator of soluble guanylate cyclase. Br. J. Pharmacol. 1999; 128: 1316-22.
    • (1999) Br. J. Pharmacol. , vol.128 , pp. 1316-1322
    • Wohlfart, P.1    Malinski, T.2    Ruetten, H.3
  • 20
    • 1642275487 scopus 로고    scopus 로고
    • Relaxing effects induced by the soluble guanylate cyclase stimulator BAY 41-2272 in human and rabbit corpus cavernosum
    • Baracat JS, Teixeira CE, Okuyama CE et al. Relaxing effects induced by the soluble guanylate cyclase stimulator BAY 41-2272 in human and rabbit corpus cavernosum. Eur. J. Pharmacol. 2003; 477: 163-9.
    • (2003) Eur. J. Pharmacol. , vol.477 , pp. 163-169
    • Baracat, J.S.1    Teixeira, C.E.2    Okuyama, C.E.3
  • 21
    • 0029122910 scopus 로고
    • Potent and selective inhibition of nitric oxide-sensitive guanylate cyclase by 1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one
    • Garthwaite J, Southam E, Boulton CL et al. Potent and selective inhibition of nitric oxide-sensitive guanylate cyclase by 1H-[1,2,4] oxadiazolo[4,3-a]quinoxalin-1-one. Mol. Pharmacol. 1995; 48: 184-8.
    • (1995) Mol. Pharmacol. , vol.48 , pp. 184-188
    • Garthwaite, J.1    Southam, E.2    Boulton, C.L.3
  • 22
    • 0029938767 scopus 로고    scopus 로고
    • Characterization of 1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one as a heme-site inhibitor of nitric oxide-sensitive guanylate cyclase
    • Schrammel A, Behrends S, Schmidt K et al. Characterization of 1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one as a heme-site inhibitor of nitric oxide-sensitive guanylate cyclase. Mol. Pharmacol. 1996; 50: 1-5.
    • (1996) Mol. Pharmacol. , vol.50 , pp. 1-5
    • Schrammel, A.1    Behrends, S.2    Schmidt, K.3
  • 23
    • 14644431766 scopus 로고    scopus 로고
    • Inhibitory effects of human eosinophil chemotaxis in vitro by BAY 41-2272, an activator of nitric oxide-independent site of soluble guanylate cyclase
    • Thomazzi SM, Moreira J, De Nucci G et al. Inhibitory effects of human eosinophil chemotaxis in vitro by BAY 41-2272, an activator of nitric oxide-independent site of soluble guanylate cyclase. Biochem. Pharmacol. 2005; 69: 875-82.
    • (2005) Biochem. Pharmacol. , vol.69 , pp. 875-882
    • Thomazzi, S.M.1    Moreira, J.2    De Nucci, G.3
  • 24
    • 0030424372 scopus 로고    scopus 로고
    • Novel guanylate cyclase inhibitor potently inhibits cyclic GMP accumulation in endothelial cells and relaxation of bovine pulmonary artery
    • Brunner F, Schmidt K, Nielsen EB. et al. Novel guanylate cyclase inhibitor potently inhibits cyclic GMP accumulation in endothelial cells and relaxation of bovine pulmonary artery. J. Pharmacol. Exp. Ther. 1996; 277: 48-53.
    • (1996) J. Pharmacol. Exp. Ther. , vol.277 , pp. 48-53
    • Brunner, F.1    Schmidt, K.2    Nielsen, E.B.3
  • 25
    • 0029833098 scopus 로고    scopus 로고
    • Inhibition of nitric oxide-induced vasodilation by gap junction inhibitors: A potential role for a cGMP-independent nitric oxide pathway
    • Javid PJ, Watts SW, Webb RC. Inhibition of nitric oxide-induced vasodilation by gap junction inhibitors: A potential role for a cGMP-independent nitric oxide pathway. J. Vasc. Res. 1996; 33: 395-404.
    • (1996) J. Vasc. Res. , vol.33 , pp. 395-404
    • Javid, P.J.1    Watts, S.W.2    Webb, R.C.3
  • 26
    • 0028220671 scopus 로고    scopus 로고
    • Nitric oxide directly activates calcium-dependent potassium channels in vascular smooth muscle
    • Bolotina VM, Najibi S, Palacino JJ et al. Nitric oxide directly activates calcium-dependent potassium channels in vascular smooth muscle. Nature 2003; 368: 850-3.
    • (2003) Nature , vol.368 , pp. 850-853
    • Bolotina, V.M.1    Najibi, S.2    Palacino, J.J.3
  • 27
    • 0032213809 scopus 로고    scopus 로고
    • Sodium nitroprusside-induced cGMP-independent vasodilator responses in the perfused rabbit ovarian vascular bed
    • Yousif MH, Oriowo MA, Williams KI. Sodium nitroprusside-induced cGMP-independent vasodilator responses in the perfused rabbit ovarian vascular bed. Pharmacol. Res. 1998; 38: 381-6.
    • (1998) Pharmacol. Res. , vol.38 , pp. 381-386
    • Yousif, M.H.1    Oriowo, M.A.2    Williams, K.I.3
  • 28
    • 0036087769 scopus 로고    scopus 로고
    • Mechanism of cGMP contribution to the vasodilator response to NO in rat middle cerebral arteries
    • Yu M, Sun CW, Maier KG et al. Mechanism of cGMP contribution to the vasodilator response to NO in rat middle cerebral arteries. Am. J. Physiol. Heart Circ. Physiol. 2002; 282: H1724-31.
    • (2002) Am. J. Physiol. Heart Circ. Physiol. , vol.282
    • Yu, M.1    Sun, C.W.2    Maier, K.G.3
  • 29
    • 0035964230 scopus 로고    scopus 로고
    • 2+ uptake activity can account for the reduced response to NO, but not sodium nitroprusside, in hypercholesterolemic rabbit orta
    • 2+ uptake activity can account for the reduced response to NO, but not sodium nitroprusside, in hypercholesterolemic rabbit orta. Circulation 2001; 104: 1040-5.
    • (2001) Circulation , vol.104 , pp. 1040-1045
    • Adachi, T.1    Matsui, R.2    Weisbrod, R.M.3
  • 30
    • 0041461858 scopus 로고    scopus 로고
    • Hypoxia enhances a cGMP-independent nitric oxide relaxing mechanism in pulmonary arteries
    • Mingone CJ, Gupte SA, Iesaki T et al. Hypoxia enhances a cGMP-independent nitric oxide relaxing mechanism in pulmonary arteries. Am. J. Physiol. Lung Cell. Mol. Physiol. 2003; 285: L296-304.
    • (2003) Am. J. Physiol. Lung Cell. Mol. Physiol. , vol.285
    • Mingone, C.J.1    Gupte, S.A.2    Iesaki, T.3
  • 31
    • 0346366927 scopus 로고    scopus 로고
    • Soluble guanylyl cyclase activator YC-1 inhibits human neutrophil functions through a cGMP-independent but cAMP-dependent pathway
    • Hwang TL, Hung HW, Kao SH et al. Soluble guanylyl cyclase activator YC-1 inhibits human neutrophil functions through a cGMP-independent but cAMP-dependent pathway. Mol. Pharmacol. 2003; 64: 1419-27.
    • (2003) Mol. Pharmacol. , vol.64 , pp. 1419-1427
    • Hwang, T.L.1    Hung, H.W.2    Kao, S.H.3
  • 32
    • 3042819388 scopus 로고    scopus 로고
    • 2 analogues elicit vascular relaxation: Cyclic AMP-independent, Gs-protein mediated-activation of MaxiK channel
    • 2 analogues elicit vascular relaxation: Cyclic AMP-independent, Gs-protein mediated-activation of MaxiK channel. Curr. Med. Chem. Cardiovasc. Hematol. Agents 2004; 2: 257-65.
    • (2004) Curr. Med. Chem. Cardiovasc. Hematol. Agents , vol.2 , pp. 257-265
    • Tanaka, Y.1    Yamaki, F.2    Koike, K.3
  • 33
    • 0021856423 scopus 로고
    • The relaxing activity of iloprost and prostaglandin E2 in the isolated various smooth muscle strips of the rabbit
    • Ercan ZS, Turker RK. The relaxing activity of iloprost and prostaglandin E2 in the isolated various smooth muscle strips of the rabbit. Pharmacology 1985; 31: 61-6.
    • (1985) Pharmacology , vol.31 , pp. 61-66
    • Ercan, Z.S.1    Turker, R.K.2
  • 34
    • 0026020318 scopus 로고
    • Inhibition of iloprost of the contractile effect of noradrenaline in mesenteric artery rings: Evidence for a possible calcium-dependent mechanism
    • Demirel E, Turker RK. Inhibition of iloprost of the contractile effect of noradrenaline in mesenteric artery rings: Evidence for a possible calcium-dependent mechanism. Prostaglandins Leukot. Essent. Fatty Acids 1991; 42: 185-9.
    • (1991) Prostaglandins Leukot. Essent. Fatty Acids , vol.42 , pp. 185-189
    • Demirel, E.1    Turker, R.K.2
  • 35
    • 0028034304 scopus 로고
    • Smooth muscle tone regulation in rabbit cavernosal and spongiosal tissue by cyclic AMP- and cyclic GMP-dependent mechanisms
    • Sparwasser C, Drescher P, Will JA et al. Smooth muscle tone regulation in rabbit cavernosal and spongiosal tissue by cyclic AMP- and cyclic GMP-dependent mechanisms. J. Urol. 1994; 152: 2159-63.
    • (1994) J. Urol. , vol.152 , pp. 2159-2163
    • Sparwasser, C.1    Drescher, P.2    Will, J.A.3
  • 36
    • 0032845246 scopus 로고    scopus 로고
    • 1 and rolipram, a selective inhibitor of the type 4 phosphodiesterase (PDE4)
    • 1 and rolipram, a selective inhibitor of the type 4 phosphodiesterase (PDE4). J. Urol. 1999; 162: 1848-55.
    • (1999) J. Urol. , vol.162 , pp. 1848-1855
    • Bivalacqua, T.J.1    Champion, H.C.2    Rajasekaran, M.3
  • 37
    • 0035885285 scopus 로고    scopus 로고
    • 2+ entry by YC-1, an activator of soluble guanylyl cyclase, through a cyclic GMP-independent pathway in rat neutrophils
    • 2+ entry by YC-1, an activator of soluble guanylyl cyclase, through a cyclic GMP-independent pathway in rat neutrophils. Biochem. Pharmacol. 2001; 62: 679-84.
    • (2001) Biochem. Pharmacol. , vol.62 , pp. 679-684
    • Wang, J.P.1    Chang, L.C.2    Huang, L.J.3
  • 38
    • 0033522211 scopus 로고    scopus 로고
    • Tissue distribution of phosphodiesterase families and the effects of sildenafil on tissue cyclic nucleotides, platelet function, and the contractile responses of trabeculae carneae and aortic rings in vitro
    • Wallis RM, Corbin JD, Francis SH et al. Tissue distribution of phosphodiesterase families and the effects of sildenafil on tissue cyclic nucleotides, platelet function, and the contractile responses of trabeculae carneae and aortic rings in vitro. Am. J. Cardiol. 1999; 83 (Suppl. 5A): C3-12.
    • (1999) Am. J. Cardiol. , vol.83 , Issue.SUPPL. 5A
    • Wallis, R.M.1    Corbin, J.D.2    Francis, S.H.3
  • 39
    • 0028811010 scopus 로고
    • Heterogeneity of endothelium-dependent mechanisms in different rabbit arteries
    • Ferrer M, Encabo A, Conde MV et al. Heterogeneity of endothelium- dependent mechanisms in different rabbit arteries. J. Vasc. Res. 1995; 32: 339-46.
    • (1995) J. Vasc. Res. , vol.32 , pp. 339-346
    • Ferrer, M.1    Encabo, A.2    Conde, M.V.3
  • 40
    • 0037405772 scopus 로고    scopus 로고
    • Effect of PDE5 inhibition on coronary hemodynamics in pacing-induced heart failure
    • Chen Y, Traverse JH, Hou M et al. Effect of PDE5 inhibition on coronary hemodynamics in pacing-induced heart failure. Am. J. Physiol. Heart Circ. Physiol. 2003; 284: H1513-20.
    • (2003) Am. J. Physiol. Heart Circ. Physiol. , vol.284
    • Chen, Y.1    Traverse, J.H.2    Hou, M.3
  • 41
    • 0034832461 scopus 로고    scopus 로고
    • The effect of sildenafil on nitric oxide-mediated vasodilation in healthy men
    • Dishy V, Sofowora G, Harris PA et al. The effect of sildenafil on nitric oxide-mediated vasodilation in healthy men. Clin. Pharmacol. Ther. 2001; 70: 270-9.
    • (2001) Clin. Pharmacol. Ther. , vol.70 , pp. 270-279
    • Dishy, V.1    Sofowora, G.2    Harris, P.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.