Structural basis for the interaction of a vascular endothelial growth factor mimic peptide motif and its corresponding receptors

Chemistry and Biology

Volumn 12, Issue 10, 2005, Pages 1075-1083

  Giordano, Ricardo J ^a   Anobom, Cristiane D ^b   Cardó Vila, Marina ^a   Kalil, Jorge ^c   Valente, Ana P ^b   Pasqualini, Renata ^a   Almeida, Fabio C L ^b   Arap, Wadih ^a  

^a UNIVERSITY OF TEXAS   (United States)

^b FEDERAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

^c UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 26944437077     PISSN: 10745521     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chembiol.2005.07.008     Document Type: Article

References (34)

1. J. Folkman, and R. Kalluri Cancer without disease Nature 427 2004 787
2. P. Carmeliet Angiogenesis in health and disease Nat. Med. 9 2003 653 660
3. J. Folkman Angiogenesis inhibitors: a new class of drugs Cancer Biol. Ther. 2 4 Suppl 1 2003 S127 S133
4. N. Ferrara, H.P. Gerber, and J. LeCouter The biology of VEGF and its receptors Nat. Med. 9 2003 669 676
5. G.H. Fong, J. Rossant, M. Gertsenstein, and M.L. Breitman Role of the Flt-1 receptor tyrosine kinase in regulating the assembly of vascular endothelium Nature 376 1995 66 70
6. A. Luttun, M. Tjwa, L. Moons, Y. Wu, A. Angelillo-Scherrer, F. Liao, J.A. Nagy, A. Hooper, J. Priller, and B. De Klerck Revascularization of ischemic tissues by PlGF treatment, and inhibition of tumor angiogenesis, arthritis and atherosclerosis by anti-Flt1 Nat. Med. 8 2002 831 840
7. M. Autiero, J. Waltenberger, D. Communi, A. Kranz, L. Moons, D. Lambrechts, J. Kroll, S. Plaisance, M. De Mol, and F. Bono Role of PlGF in the intra- and intermolecular cross talk between the VEGF receptors Flt1 and Flk1 Nat. Med. 9 2003 936 943
8. F. Pipp, M. Heil, K. Issbrucker, T. Ziegelhoeffer, S. Martin, J. van den Heuvel, H. Weich, B. Fernandez, G. Golomb, and P. Carmeliet VEGFR-1-selective VEGF homologue PlGF is arteriogenic: evidence for a monocyte-mediated mechanism Circ. Res. 92 2003 378 385
9. T. Kawasaki, T. Kitsukawa, Y. Bekku, Y. Matsuda, M. Sanbo, T. Yagi, and H. Fujisawa A requirement for neuropilin-1 in embryonic vessel formation Development 126 1999 4895 4902
10. 165-receptor binding J. Cell. Biochem. 85 2002 357 368
11. B.M. Weinstein Vessels and nerves: marching to the same tune Cell 120 2005 299 302
12. G. Vogel Developmental biology: the unexpected brains behind blood vessel growth Science 307 2005 665 667
13. A. Eichmann, F. Le Noble, M. Autiero, and P. Carmeliet Guidance of vascular and neural network formation Curr. Opin. Neurobiol. 15 2005 108 115
14. T. Yasuhara, T. Shingo, and I. Date The potential role of vascular endothelial growth factor in the central nervous system Rev. Neurosci. 15 2004 293 307
15. K. Jin, Y. Zhu, Y. Sun, X.O. Mao, L. Xie, and D.A. Greenberg Vascular endothelial growth factor (VEGF) stimulates neurogenesis in vitro and in vivo Proc. Natl. Acad. Sci. USA 99 2002 11946 11950
16. L. Cao, X. Jiao, D.S. Zuzga, Y. Liu, D.M. Fong, D. Young, and M.J. During VEGF links hippocampal activity with neurogenesis, learning and memory Nat. Genet. 36 2004 827 835
17. R.J. Giordano, M. Cardó-Vila, J. Lahdenranta, R. Pasqualini, and W. Arap Biopanning and rapid analysis of selective interactive ligands Nat. Med. 7 2001 1249 1253
18. T. Makinen, B. Olofsson, T. Karpanen, U. Hellman, S. Soker, M. Klagsbrun, U. Eriksson, and K. Alitalo Differential binding of vascular endothelial growth factor B splice and proteolytic isoforms to neuropilin-1 J. Biol. Chem. 274 1999 21217 21222
19. B.J. Stockman, and C. Dalvit NMR screening techniques in drug discovery and drug design Prog. Nucl. Magn. Reson. 41 2002 187 231
20. R.M. Cooke Protein-ligand interaction: examples in drug design D.J. Craik NMR in Drug Design 1996 CRC Press New York 245 274
21. J.R. Pires, F. Taha-Nejad, F. Toepert, T. Ast, U. Hoffmuller, J. Schneider-Mergener, R. Kuhne, M.J. Macias, and H. Oschkinat Solution structures of the YAP65 WW domain and the variant L30 K in complex with the peptides GTPPPPYTVG, N-(n-octyl)-GPPPY and PLPPY and the application of peptide libraries reveal a minimal binding epitope J. Mol. Biol. 314 2001 1147 1156
22. A. Abragam Principles of nuclear magnetism International series of monographs on physics vol. 32 1961 Oxford Science Publications, Clarendon Press Oxford 264 353
23. R. Pasqualini, E. Koivunen, and E. Ruoslahti Alpha v integrins as receptors for tumor targeting by circulating ligands Nat. Biotechnol. 15 1997 542 546
24. M.A. Burg, R. Pasqualini, W. Arap, E. Ruoslahti, and W.B. Stallcup NG2 proteoglycan-binding peptides target tumor neovasculature Cancer Res. 59 1999 2869 2874
25. R. Pasqualini, E. Koivunen, R. Kain, J. Lahdenranta, M. Sakamoto, A. Stryhn, R.A. Ashmun, L.H. Shapiro, W. Arap, and E. Ruoslahti Aminopeptidase N is a receptor for tumor-homing peptides and a target for inhibiting angiogenesis Cancer Res. 60 2000 722 727
26. S. Marchiò, J. Lahdenranta, R.O. Schlingemann, D. Valdembri, P. Wesseling, M.A. Arap, A. Hajitou, M.G. Ozawa, M. Trepel, and R.J. Giordano Aminopeptidase A is a functional target in angiogenic blood vessels Cancer Cell 5 2004 151 162
27. W. Arap, M. Kolonin, M. Trepel, M. Cardó-Vila, J. Lahdenranta, R.J. Giordano, P.J. Mintz, P.U. Ardelt, V.J. Yao, and C.I. Vidal Steps toward mapping the human vasculature by phage display Nat. Med. 8 2002 121 127
28. W.J. Fairbrother, M.A. Champe, H.W. Christinger, B.A. Keyt, and M.A. Starovasnik Solution structure of the heparin-binding domain of vascular endothelial growth factor Structure 6 1998 637 648
29. N. Ferrara, K.J. Hillan, H.P. Gerber, and W. Novotny Discovery and development of bevacizumab, an anti-VEGF antibody for treating cancer Nat. Rev. Drug Discov. 3 2004 391 400
30. J.C. Yang, L. Haworth, R.M. Sherry, P. Hwu, D.J. Schwartzentruber, S.L. Topalian, S.M. Steinberg, H.X. Chen, and S.A. Rosenberg A randomized trial of bevacizumab, an anti-vascular endothelial growth factor antibody, for metastatic renal cancer N. Engl. J. Med. 349 2003 427 434
31. M. Piotto, V. Saudek, and V. Sklenar Gradient-tailored excitation for single-quantum NMR spectroscopy of aqueous solutions J. Biomol. NMR 2 1992 661 665
32. V. Sklenar, M. Piotto, R. Leppik, and V. Sandek Gradient-tailored water suppression for 1H-15N HSQC experiments optimized to retain full sensitivity J. Magn. Reson. A 102 1993 241 245
33. A. Bax, and D.G. Davis MLEV-17-based two-dimensional homonuclear magnetization transfer spectroscopy J. Magn. Reson. 65 1985 355 360
34. N. Guex, and M.C. Peitsch SWISS-MODEL and the Swiss-PdbViewer: an environment for comparative protein modelling Electrophoresis 18 1997 2714 2723