The medical complications of alcohol use: Understanding mechanisms to improve management

Drug and Alcohol Review

Volumn 24, Issue 3, 2005, Pages 253-265

  Chase, Vicki ^a,b   Neild, Rose ^a,b   Sadler, Craig W ^a,b   Batey, Robert G ^a,b,c  

^a UNIVERSITY OF NEWCASTLE   (Australia)

^b Hunter New England Area Health Service   (Australia)

^c Drug and Alcohol Clinical Services   (Australia)

Author keywords

Alcohol; Alcohol related tissue injury; Cytokines; Drug metabolism; Genetic susceptibility; Organ damage; Oxidative stress

Indexed keywords

CYTOKINE;

ALCOHOLISM; GENETIC PREDISPOSITION; HEALTH STATUS; HUMAN; IMMUNOLOGY; MULTIPLE ORGAN FAILURE; NEOPLASM; REVIEW;

ALCOHOL-RELATED DISORDERS; CYTOKINES; GENETIC PREDISPOSITION TO DISEASE; HEALTH STATUS; HUMANS; MULTIPLE ORGAN FAILURE; NEOPLASMS;

EID: 26844562030     PISSN: 09595236     EISSN: 14653362     Source Type: Journal    
DOI: 10.1080/09595230500167510     Document Type: Review

References (81)

1. Karch SB. Karch's Pathology of drug abuse, 3rd edn. FL, USA: CRC Press, 2002.
2. Graham, AW, Schulz, TK, Mayo-Smith, MF, Ries RK, Wilford BB. eds. Principles of addiction medicine, 3rd edn. MD, USA: American Society of Addiction Medicine, 2003.
3. Malliard ME, Sorrell MF. Alcoholic liver disease 2004 (October 2004). Available at Harrison's online at: http//harrisons.accessmedicine.com
4. Neuberger J. Chapter 14: Toxic mechanisms: alcohol. In: Tomlinson S, Heagerty AM, Weetman AP, eds. Mechanisms of disease. An introduction to clinical science. Cambridge: Cambridge University Press, 1997:389-411.
5. Norton R, Batey RG, Dwyer T, McMahon S. Alcohol consumption and the risk of alcohol-related cirrhosis in women. Br Med J 1987;295:80-2.
6. Badger TM, Ronis Martin JJ, Seitz HK, Albano E, Ingleman-Sundberg M, Lieber CS. Alcohol metabolism: role in toxicity and carcinogenesis. Alcohol Clin Exp Res 2003;27:336-47.
7. Wilson JS, Apte MV. Role of alcohol metabolism in alcoholic pancreatitis. Pancreas 2003;27:311-15.
8. Le TH, Caldwell SH, Redick JA et al. The zonal distribution of megamitochondria with crystalline inclusions in nonalcoholic steatohepatitis. Hepatology 2004;39:1423-9.
9. Niemela O, Parkkila S, Worrall S, Emery PW, Preedy VR. Generation of aldehyde-derived protein modifications in ethanol exposed heart. Alcohol Clin Exp Res 2003;27:1987-92.
10. Worrall S, Niemela O, Parkkila S, Peters TJ, Preedy VR. Protein adducts in type I and type II fibre predominant muscle in the ethanol-fed rat: preferential localization in the sarcolemmal region. Eur J Clin Invest 2001;31:723-30.
11. Lands WE, Pawlosky RJ, Salem N. Alcoholism, antioxidant status and essential fatty acids. In: Papas A, ed. Antioxidant status, diet, nutrition and health. Boca Raton, FL: CRC Press, 1999:299-346.
12. Andrews DL, Williams GS, Mahoney JC, West JR. DNA fragmentation during exposure of rat cerebella to ethanol under hypoxia imposed in vitro. J Neurobiol 1999;38:82-92.
13. Heaton MB, Moore DB, Paiva M, Madorsky I, Mayer J, Shaw G. The role of neurotrophic factors, apoptosis-related proteins, and endogenous antioxidants in the differential temporal vulnerability of neonatal cerebellum to ethanol. Alcohol Clin Exp Res 2003;27:657-69.
14. Papas A, ed. Antioxidant status, diet, nutrition and health. Boca Raton, FL: CRC Press, 1999.
15. Russo D, Purohit V, Foudin L, Salin M. Workshop on alcohol use and health disparities 2002: a call to arms. Alcohol 2004;32:37-43.
16. Wilke A, Kaiser A, Ferency I, Maisch B. Alcohol and myocarditis. Herz 1996;21:248-57.
17. Pyne DB, Gleeson M, McDonald WA, Clancy RL, Perry C Jr, Fricker PA. Training strategies to maintain immuno-competence in athletes. Int J Sports Med 2000;21:851-60.
18. Cook RT. Alcohol abuse, alcoholism and damage to the immune system-a review. Alcohol Clin Exp Res 1998;22:1927-42
19. Li F, Cook RT, Alber C, Rasmussen W, Stapleton JT, Bailas ZK. Ethanol and natural killer cells. II. Stimulation of human natural killer cell activity by ethanol in vitro. Alcohol Clin Exp Res 1997;21:981-7.
20. Hines IN, Wheeler MD. Recent advances in alcoholic liver disease. III. Role of the innate immune response in alcoholic hepatitis. Am J Physiol Gastrointest Liver Physiol 2004;287:G310-4.
21. Batey RG, Wang J. Molecular pathogenesis of T lymphocyte induced liver injury in alcoholic hepatitis. Front Biosci 2002;7:1662-75.
22. Spies CD, von Drossow V, Eggers V et al. Altered cell-mediated immunity and increased post-operative infection rate in long-term alcoholic patients. Anesthesiology 2004;100:1088-100.
23. Szabo G, Catalano D, White B, Mandrekar P. Acute alcohol consumption inhibits accessory cell function of monocytes and dendritic cells. Alcohol Clin Exp Res 2004;28:824-8.
24. Grove J, Daly AK, Bassendine MF, Day CP. Association of a tumor necrosis factor promoter polymorphism with susceptibility to alcoholic steatohepatitis. Hepatology 1997;26:143-6.
25. Bhagwandeen BS, Apte M, Manwarring L, Dickeson J. Endotoxin induced hepatic necrosis in rats on an alcohol diet. J Pathol 1987;152:47-53.
26. Drenick EJ, Fisler J, Johnson D. Hepatic steatosis after intestinal bypass-prevention and reversal by metronidazole irrespective of protein-calorie malnutrition. Gastroenterology 1982;82:535-48.
27. Kimmings AN, van Deventer SJ, Obertop H, Rauws EA, Huibregtse M, Gouma DJ. Endotoxin, cytokines and endotoxin binding proteins in obstructive jaundice and after preoperative biliary drainage. Gut 2000;46:725-31.
28. Baxter JN, Jenkins SA, Shields R. SMS 210-995 and variceal haemorrhage. Acta Endocrinol Suppl (Copenh) 1987;286:37-44.
29. Bolke E, Jehle PM, Storck M, Nothnagel B, Stanescu A, Orth K. Endotoxin release and endotoxin neutralizing capacity during colonoscopy. Clin Chim Acta 2001;303:49-53.
30. Xu A, Wang Y, Keshaw H, Xu LY, Lam KS, Cooper GJ. The fat-derived hormone adiponectin alleviates alcoholic and nonalcoholic fatty liver disease in mice. J Clin Invest 2003;112:91-100.
31. Lee W. Hepatitis B virus infection. N Engl J Med 1997;337:1733-44.
32. Brown RS, Gaglio PJ. Scope of worldwide hepatitis C problem. Liver Transpl 2003;9:S10-13.
33. Morgan TR, Brenner D, Everhart J et al. Hepatitis C and alcohol: fundamental and translational research directions. Alcohol Clin Exp Res 2003;27:726-31.
34. Brechot C. Hepatitis B and C viruses and primary liver cancer. Ballières Clin. Gastroenterol 1996;10:335-73.
35. Sadfar K, Schiff E. Seminars in liver disease. Alcohol Alcohol Liver Dis 2004;24:305-15.
36. Bellentani S, Pozzato G, Saccoccio G et al. Clinical course and risk factors of hepatitis C virus related liver disease in the general population. Gut 1999;44:874-80.
37. Harris DR, Gonin R, Alter HJ et al. The relationship of acute transfusion-associated hepatitis to the development of cirrhosis in the presence of alcohol abuse. Ann Intern Med 2001;134:120-4.
38. Poynard T, Bedossa P, Opolon P. Natural history of liver fibrosis progression in patients with chronic hepatitis C. Lancet 1997;349:825-32.
39. Rigamonti C, Mottaran E, Reale E et al. Moderate consumption increase oxidative stress in patients with chronic hepatitis C. Hepatology 2003;38:42-9.
40. Peters MG, Terrault NA. Alcohol use and Hepatitis C. Hepatology 2002;36:S220-5.
41. Department of Health and Ageing. Australian Alcohol Guidelines. 2003 (October 2004). Available at: www.alco-holguidelines.gov.au
42. Farrell GC. Hepatitis C other liver disorders and liver health. A practical guide 2002. Eastgardens: MacLennan & Petty Pty Ltd, 2002.
43. Lonardo A, Loria P. Of liver, whisky and plants: a requiem for colchicine in alcoholic cirrhosis? Eur J Gastroenterol Hepatol 2002;14:355-8.
44. Day CP, Saksena S. Non-alcoholic steatohepatitis: definitions and pathogenesis. J Gastroenterol Hepatol 2002; 17: S377-84.
45. Huber DA. Nonalcoholic steatohepatitis (NASH) syndrome. Gastroenterol Nurs 2004;27:55-8.
46. Pietrangelo A. Hereditery hemachromatosis - a new look at an old disease. N Engl J Med 2004;350:2383-95
47. Cotran RS. Robbins pathological basis of disease, 6th edition. Philadelphia: Saunders, 1999.
48. Vachon CM, Cerhan JR, Vierkant RA, Sellers TA. Investigation of an interaction of alcohol intake and family history on breast cancer risk in the Minnesota breast cancer family study. Cancer 2001;92:240-8.
49. Ashley MJ, Ferrence R, Room R, Bondy S, Rehm J, Single E. Moderate drinking and health: implications of recent evidence. Can Fam Physician 1997;43:687-94.
50. Feinman L, Lieber CS. Medical disorders in the addicted patient: nutrition. In: Graham AW, Schultz TK, eds. Principles of addiction medicine. Chevy Chase, MD: American Society of Addiction Medicine Inc., 1998:741-53.
51. Brody T, ed. Nutritional biochemistry. San Diego, CA: Academic Press Inc., 1994.
52. Barker HM, ed. Nutrition and dietetics for health care. Edinburgh: Harcourt Publishers, 2002.
53. NH&MRC Guidelines. Recommended dietary intakes for use in Australia, part 4. 2001 (October 2004). Available at: www.nhmrc.gov.au
54. Hillers VN, Massey LK. Interrelationships of moderate and high alcohol consumption with diet and health status. Am J Clin Nutr 1985;41:356-62.
55. Manari AP, Preedy VR, Peters TJ. Nutritional intake of hazardous drinkers and dependant alcoholics in the UK. Addict Biol 2003;8:201-10.
56. Green PH. Alcohol, nutrition and malabsorption. Clin Gastroenterol 1983;12:563-74.
57. van den Berg H, van der Gaag M, Hendriks H. Influence of lifestyle on vitamin bioavailability. Int J Vitam Nutr Res 2002;72:53-9.
58. Mendenhall C, Roselle GA, Moritz T et al. Relationship of protein calorie malnutrition to alcoholic liver disease: a reexamination of data from two Veterans Administration Cooperative Studies. Alcohol Clin Exp Res 1995;19:635-41.
59. Kalman DR, Saltzmann JR. Nutritional status predicts survival in cirrhosis. Nutr Rev 1996;54:217- 19.
60. Naveau S, Giraud V, Borotto E et al. Excess weight risk factor for alcoholic liver disease. Hepatology 1997;25:108-11.
61. Lieber CS. Medical disorders in the addicted patient: Hepatic disorders. In: Graham AW, Schultz TK, eds. Principles of addiction medicine. Chevy Chase, MD: American Society of Addiction Medicine, Inc., 1998:754-74.
62. Valeric LG, Parks T, Peterson DR. Alcohol mediates increases in hepatic and serum non heme iron stores in a rat model for alcohol-induced liver injury. Alcohol Clin Exp Res 1996;20:1352-61.
63. Tsukamoto H, Lin M, Ohata M et al. Iron primes hepatic macrophages for NFΚB activation in alcoholic liver injury. Am J Physiol 1999;277:1240-50.
64. Molina PE, Hoek JB, Nelson S et al. Mechanisms of alcohol-induced tissue injury. Alcohol Clin Exp Res 2003;27:563-75.
65. Lee TD, Sadda MR, Mendier MH et al. Abnormal hepatic methionine and glutathione metabolism in patients with alcoholic hepatitis. Alcohol Clin Exp Res 2004;28:173-81.
66. Special Report-US Congress 'Alcohol and Health'. NIAAA, Washington, DC, 2000.
67. Kalousova M, Zima T, Popov P et al. Advanced glycation end-products in patients with chronic alcohol misuse. Alcohol Alcohol 2004;39:16-20.
68. Poschl G, Stickel F, Wang XD et al. Alcohol and cancer: genetic and nutritional aspects. Proc Nutr Soc 2004;63:65-71.
69. Fernandez-Sola J, Garcia G, Elena M et al. Muscle antioxidant status in chronic alcoholism. Alcohol Clin Exp Res 2002;26:1858-62.
70. Bjørneboe A, Bjørneboe GE. Antioxidant status and alcohol-related diseases. Alcohol Alcohol 1993;28:111-16.
71. Lieber CS. Alcohol, liver and nutrition. J Am Coll Nutr 1991;10:602-32.
72. Leo MA, Lieber CS. Hypervitaminosis A: a liver lover's lament. Hepatology 1988;8:412-17.
73. Lieber CS. Interaction of ethanol with drugs, hepatotoxic agents, carcinogens and vitamins. Alcohol Alcohol 1990;25:157-76.
74. World MJ, Ryle PR, Thomson AD. Alcoholic malnutrition and the small intestine. Alcohol Alcohol 1985;20:89-124.
75. Salaspuro M. Nutrient intake and nutritional status in alcoholics. Alcohol Alcohol 1993;28:85-8.
76. Lieber CS. Alcoholic liver injury: pathogenesis and therapy in 2001. Pathol Biol (Paris) 2001;49:738-52.
77. Lieber CS. S-adenosyl-L-methionine: its role in the treatment of liver disease. Am J Clin Nutr 2002;76:1183S-1187S.
78. Aleynik SI, Lieber CS. Polyenylphosphatidylcholine corrects the alcohol-induced hepatic oxidative stress by restoring s-adenosylmethionine. Alcohol Alcohol 2003;38:208-12.
79. Naveau S, Chollett-Martin S, Dharancy S et al. Foie-Alcool group of the Association Francaise pour l'Etude du Foie. A double-blind randomized controlled trial of infliximab associated with prednisolone in acute alcoholic hepatitis. Hepatology 2004;39:1390-7.
80. Song Z, Joshi-Barve S, Barve S, McClain CJ. Advances in alcoholic liver disease. Curr Gastroenterol Rep 2004;6:71-6.
81. Ramstedt M. Alcohol and pancreatitis mortality at the population level: experiences from 14 western countries. Addiction 2004;99:1255-61.