A bifunctional Gαi/Gαs modulatory peptide that attenuates adenylyl cyclase activity

FEBS Letters

Volumn 579, Issue 25, 2005, Pages 5746-5750

  Johnston, Christopher A ^a,b   Ramer, J Kevin ^c,e   Blaesius, Rainer ^c,f   Fredericks, Zoey ^c,g   Watts, Val J ^d   Siderovski, David P ^a,b  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF NORTH CAROLINA   (United States)

^c Karo Bio USA   (United States)

^d PURDUE UNIVERSITY   (United States)

^e Hemocellular Therapeutics   (United States)

^f Becton Dickinson Technologies   (United States)

^g AMGEN INC   (United States)

Author keywords

Adenylyl cyclase; Biosensors; G proteins; Phage display; Signal transduction; Surface plasmon resonance

Indexed keywords

ADENYLATE CYCLASE; GUANOSINE 5' O (3 THIOTRIPHOSPHATE); INHIBITORY GUANINE NUCLEOTIDE BINDING PROTEIN; PEPTIDE; PROTEIN KB 752; STIMULATORY GUANINE NUCLEOTIDE BINDING PROTEIN; UNCLASSIFIED DRUG; KB 752 PEPTIDE; KB-752 PEPTIDE;

ARTICLE; CELL MEMBRANE; ENZYME ACTIVATION; ENZYME ACTIVITY; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN FUNCTION; REGULATORY MECHANISM; CELL CULTURE; DRUG ANTAGONISM; DRUG EFFECT; SIGNAL TRANSDUCTION;

ADENYLATE CYCLASE; CELLS, CULTURED; GTP-BINDING PROTEIN ALPHA SUBUNITS, GI-GO; GTP-BINDING PROTEIN ALPHA SUBUNITS, GS; HUMANS; PEPTIDES; SIGNAL TRANSDUCTION;

EID: 26844548024     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.febslet.2005.09.059     Document Type: Article

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