Expression of pro-Muclin in pancreatic AR42J cells induces functional regulated secretory granules

American Journal of Physiology - Cell Physiology

Volumn 289, Issue 5 58-5, 2005, Pages

  De Lisle, Robert C ^a   Norkina, Oxana ^a   Roach, Eileen ^a   Ziemer, Donna ^a  

^a UNIVERSITY OF KANSAS SCHOOL OF MEDICINE   (United States)

Author keywords

Protein sorting; Regulated secretion

Indexed keywords

CERULETIDE; COMPLEMENTARY DNA; DEXAMETHASONE; GLYCOPROTEIN; GREEN FLUORESCENT PROTEIN; MEMBRANE PROTEIN; PRO MUCLIN; UNCLASSIFIED DRUG;

ADENOVIRUS; ANIMAL CELL; ARTICLE; CELL CULTURE; CELL ULTRASTRUCTURE; CONTROLLED STUDY; ELECTRON MICROSCOPY; NONHUMAN; NUCLEOTIDE SEQUENCE; PANCREAS CELL; PLASMID; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN TARGETING; RAT; REGULATED SECRETORY GRANULE; SECRETORY GRANULE; VIRUS RECOMBINANT;

AMYLASES; ANIMALS; CAERULEIN; CELL LINE; DEXAMETHASONE; GENE EXPRESSION REGULATION; GLUCOCORTICOIDS; MUCOPROTEINS; PANCREAS; PROTEIN SUBUNITS; RATS; SECRETORY VESICLES;

ADENOVIRIDAE;

EID: 26844534432     PISSN: 03636143     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpcell.00099.2005     Document Type: Article

References (41)

1. Abrink M, Grujic M, and Pejler G. Serglycin is essential for maturation of mast cell secretory granule. J Biol Chem 279: 40897-40905, 2004.
2. Arvan P and Castle D. Sorting and storage during secretory granule biogenesis: looking backward and looking forward. Biochem J 332: 593-610, 1998.
3. Arvan P, Zhang BY, Feng LJ, Liu M, and Kuliawat R. Lumenal protein multimerization in the distal secretory pathway/secretory granules. Curr Opin Cell Biol 14: 448-453, 2002.
4. Boulatnikov I and De Lisle RC. Binding of the Golgi sorting receptor Muclin to pancreatic zymogens through sulfated O-linked oligosaccharides. J Biol Chem 279: 40918-40926, 2004.
5. Cesarone CF, Bolognesi C, and Santi L. Improved microfluorometric DNA determination in biological material using 33258 Hoechst. Anal Biochem 100: 188-197, 1979.
6. Chen X, Li C, Izumi T, Ernst SA, Andrews PC, and Williams JA. Rab27b localizes to zymogen granules and regulates pancreatic acinar exocytosis. Biochem Biophys Res Commun 323: 1157-1162, 2004.
7. Chen XQ, Ernst SA, and Williams JA. Dominant negative Rab3D mutants reduce GTP-bound endogenous Rab3D in pancreatic acini. J Biol Chem 278: 50053-50060, 2003.
8. Chobert MN, Grondin G, Brouillet A, Laperche Y, and Beaudoin AR. Control of γ-glutamyl transpeptidase expression by glucocorticoids in the rat pancreas. Correlation with granule formation. J Biol Chem 271: 12431-12437, 1996.
9. Colomer V, Kicska GA, and Rindler MJ. Secretory granule content proteins and the luminal domains of granule membrane proteins aggregate in vitro at mildly acidic pH. J Biol Chem 271: 48-55, 1996.
10. Cook TA, Mesa KJ, Gebelein BA, and Urrutia RA. Upregulation of dynamin II expression during the acquisition of a mature pancreatic acinar cell phenotype. J Histochem Cytochem 44: 1373-1378, 1996.
11. fat mice. Cell 88: 73-83, 1997.
12. De Lisle RC. Characterization of the major sulfated protein of mouse pancreatic acinar cells: a high molecular weight peripheral membrane glycoprotein of zymogen granules. J Cell Biochem 56: 385-396, 1994.
13. De Lisle RC. Role of sulfated O-linked glycoproteins in zymogen granule formation. J Cell Sci 115: 2941-2952, 2002.
14. De Lisle RC, Petitt M, Huff J, Isom KS, and Agbas A. Muclin expression in the cystic fibrosis transmembrane conductance regulator knockout mouse. Gastroenterology 113: 521-532, 1997.
15. De Lisle RC, Schulz I, Tyrakowski T, Haase W, and Hopfer U. Isolation of stable pancreatic zymogen granules. Am J Physiol Gastrointest Liver Physiol 246: G411-G418, 1984.
16. De Lisle RC and Ziemer D. Processing of pro-Muclin and divergent targeting of its products to zymogen granules and the apical plasma membrane of pancreatic acinar cells. Eur J Cell Biol 79: 892-904, 2000.
17. Doyon Y, Home W, Daull P, and LeBel D. Effect of C-domain N-glycosylation and deletion on rat pancreatic α-amylase secretion and activity. Biochem J 362: 259-264, 2002.
18. Gaisano HY, Huang X, Sheu L, Ghai M, Newgard CB, Trinh KY, and Trimble WS. Snare protein expression and adenoviral transfection of amphicrine AR42J. Biochem Biophys Res Commun 260: 781-784, 1999.
19. Ghosh P and Kornfeld S. The GGA proteins: key players in protein sorting at the trans-Golgi network. Eur J Cell Biol 83: 257-262, 2004.
20. Gorr SU and Tseng SY. Aggregation and concentration-dependent sorting of exocrine regulated secretory proteins. Biochem Biophys Res Commun 215: 82-88, 1995.
21. Jain RK, Joyce PBM, Molinete M, Halban PA, and Gorr SU. Oligomerization of green fluorescent protein in the secretory pathway of endocrine cells. Biochem J 360: 645-649, 2001.
22. Jessop NW and Hay RJ. Characteristics of two rat pancreatic exocrine cell lines derived from transplantable tumors (Abstract). In Vitro 16: 212, 1980.
23. Kelly RB. Pathways of protein secretion in eukaryotes. Science 230: 25-32, 1985.
24. 2+-regulated versus constitutive exocytosis. J Neurosci 23: 10531-10539, 2003.
25. Klengel R, Piiper A, Pittelkow S, and Zeuzem S. Differential expression of Rab3 isoforms during differentiation of pancreatic acinar cell line AR42J. Biochem Biophys Res Commun 236: 719-722, 1997.
26. Kullman J, Gisi C, and Lowe ME. Dexamethasone-regulated expression of pancreatic lipase and two related proteins in AR42J cells. Am J Physiol Gastrointest Liver Physiol 270: G746-G751, 1996.
27. Logsdon CD, Moessner J, Williams JA, and Goldfine ID. Glucocorticoids increase amylase mRNA levels, secretory organelles, and secretion in pancreatic acinar AR42J cells. J Cell Biol 100: 1200-1208, 1985.
28. Loh YP, Kim T, Rodriguez YM, and Cawley NX. Secretory granule biogenesis and neuropeptide sorting to the regulated secretory pathway in neuroendocrine cells. J Mol Neurosci 22: 63-71, 2003.
29. Matsumoto M, Miki T, Shibasaki T, Kawaguchi M, Shinozaki H, Nio J, Saraya A, Koseki H, Miyazaki M, Iwanaga T, and Seino S. Noc2 is essential in normal regulation of exocytosis in endocrine and exocrine cells. Proc Natl Acad Sci USA 101: 8313-8318, 2004.
30. Otte S and Barlowe C. Sorting signals can direct receptor-mediated export of soluble proteins into COP11 vesicles. Nat Cell Biol 6: 1189-1194, 2004.
31. Qiu X, Valentijn JA, and Jamieson JD. Carboxyl-methylation of rab3D in the rat pancreatic acinar tumor cell line AR42J. Biochem Biophys Res Commun 285: 708-714, 2001.
32. Rajasekaran AK, Morimoto T, Hanzel DK, Rodriguez-Boulan E, and Kreibich G. Structural reorganization of the rough endoplasmic reticulum without size expansion accounts for dexamethasone-induced secretory activity in AR42J cells. J Cell Sci 105: 333-345, 1993.
33. Rosewicz S, Detjen K, Logsdon CD, Chen LM, Chao J, and Riecken EO. Glandular kallikrein gene expression is selectively down-regulated by glucocorticoids in pancreatic AR42J cells. Endocrinology 128: 2216-2222, 1991.
34. Schlegel A, Arvan P, and Lisanti MP. Caveolin-1 binding to endoplasmic reticulum membranes and entry into the regulated secretory pathway are regulated by serine phosphorylation. Protein sorting at the level of the endoplasmic reticulum. J Biol Chem 276: 4398-4408, 2001.
35. Schrader M. Membrane targeting in secretion. Subcell Biochem 37: 391-421, 2004.
36. Sollner TH. Intracellular and viral membrane fusion: a uniting mechanism. Curr Opin Cell Biol 16: 429-435, 2004.
37. Tandon C and De Lisle RC. Apactin is involved in remodeling of the actin cytoskeleton during regulated exocytosis. Eur J Cell Biol 83: 79-89, 2004.
38. Thiele C, Gerdes HH, and Huttner WB. Protein secretion: puzzling receptors. Curr Biol 7: R496-R500, 1997.
39. Wang CC, Ng CP, Lu L, Atlashkin V, Zhang W, Seet LF, and Hong W. A role of VAMP8/endobrevin in regulated exocytosis of pancreatic acinar cells. Dev Cell 7: 359-371, 2004.
40. Williams JA, Korc M, and Dormer RL. Action of secretagogues on a new preparation of functionally intact, isolated pancreatic acini. Am J Physiol Endocrinol Metab Gastrointest Physiol 235: E517-E524, 1978.
41. Yu S, Hao Y, and Lowe AW. Effects of GP2 expression on secretion and endocytosis in pancreatic AR4-2J cells. Biochem Biophys Res Commun 322: 320-325, 2004.