Dexamethasone-regulated expression of pancreatic lipase and two related proteins in AR42J cells

American Journal of Physiology - Gastrointestinal and Liver Physiology

Volumn 270, Issue 5 33-5, 1996, Pages

  Kullman, John ^a   Gisi, Catherine ^a   Lowe, Mark E ^a,b  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b ST LOUIS CHILDREN S HOSPITAL   (United States)

Author keywords

glucocorticoids; messenger ribonucleic acids; protein secretion

Indexed keywords

DEXAMETHASONE; MESSENGER RNA; TRIACYLGLYCEROL LIPASE;

ACINAR CELL; ANIMAL CELL; ARTICLE; GENE EXPRESSION REGULATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN SECRETION; RNA ANALYSIS; RNA METABOLISM;

EID: 0029970037     PISSN: 01931857     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpgi.1996.270.5.g746     Document Type: Article

References (19)

1. Bradford, M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of7 protein-dye binding. Anal. Biochem. 72: 248-251, 1976.
2. Christophe, J. The pancreatic tumoral cell line AR42J: an amphicrine model. Am. J. Physiol. 266 (Gastrointest. Liver Physiol. 29): G963-G971, 1994.
3. Deschodt-Lanckman, M., P. Robberecht, J. Camus, C. Baya, and J. Christophe. Hormonal and dietary adaptation of rat pancreatic hydrolases before and after weaning. Am. J. Physiol. 226: 39-44, 1974.
4. Giller, T., P. Buchwald, D. Blum-Kaelin, and W. Hunziker. Two novel human pancreatic lipase related proteins, hPLRPl and hPLRP2. J. Biol. Chem. 267:16509-16516, 1992.
5. Henning, S. Plasma concentrations of total and free corticosterone during development in the rat. Am. J. Physiol. 235 (Endocrinol. Metab. Gastrointest. Physiol. 4): E451-E456, 1978.
6. Lerner, A., P. C. Lee, and E. Lebenthal. Chemical adrenalectomy by aminoglutethimide and the pancreas in suckling rats. Am. J. Physiol. 247 (Gastrointest. Liver Physiol. 10): G346-G351, 1984.
7. Logsdon, C. D. Glucocorticoids increase cholecystokinin receptors and amylase secretion in pancreatic acinar AR42J cells. J. Biol. Chem. 261: 2096-2101, 1986.
8. Logsdon, C. D., J. Moessner, J. A. Williams, and I. D. Goldfine. Glucocorticoids increase amylase mRNA levels, secre-tory organelles, and secretion in pancreatic acinar AR42J cells. J. Cell Biol. 100: 1200-1208, 1985.
9. Logsdon, C. D., K. J. Perot, and A. R. McDonald. Mechanism of glucocorticoid-induced increase in pancreatic amylase gene transcription. J. Biol. Chem. 262: 15765-15769, 1987.
10. Lowe, M. E. The catalytic site residues and interfacial binding of human pancreatic lipase. J. Biol. Chem. 267: 17029-17073, 1992.
11. Martin, C. E., M. H. Cake, P. E. Hartmann, and I. F. Cook. Relationship between foetal corticosteroids, maternal progesterone and parturition in the rat. Acta Endocrinol. 84: 167-176, 1977.
12. Payne, R. M., H. F. Sims, M. L. Jennens, and M. E. Lowe. Rat pancreatic lipase and two related proteins: enzymatic properties and mRNA expression during development. Am. J. Physiol 266 (Gastrointest. Liver Physiol. 29): G914-G921, 1994.
13. Puccio, F., J. Chariot, and T. Lehy. Influence of hydrocortisone on the development of pancreas in suckling rats. Biol. Neonate 54: 35-44, 1988.
14. Rosewicz, S., and C. D. Logsdon. Pancreatic kallikrein gene expression: effects of glucocorticoids in vivo and in vitro. Gastroenterology 97:1005-1010, 1989.
15. Rosewicz, S., and C. D. Logsdon. Glucocorticoids stimulate ornithine decarboxylase gene expression in pancreatic AR42J cells. Gastroenterology 101: 1102-1108, 1991.
16. Slater, E. P., H. Hesse, J. M. Muller, and M. Beato. Glucocorticoid receptor binding site in the mouse α-amylase 2 gene mediates response to the hormone. Mol. Endocrinol. 7: 907-914, 1993.
17. Swarovsky, B., W. Steinhilber, G. A. Scheele, and H. F. Kern. Coupled induction of exocrine proteins and intracellular compartments involved in the secretory pathway in AR42J cells by glucocorticoids, J. Cell Biol. 47: 101-111, 1988.
18. Thirstrup, K., R. Verger, and F. Carrìre. Evidence for a pancreatic lipase subfamily with new kinetic properties. Biochemistry 33: 2784-2756, 1994.
19. Wicker-Planquart, C., and A. Puigserver. Primary structure of rat pancreatic lipase mRNA.FEBS Lett. 1:61-66, 1992.