D-amino acid containing, high-affinity inhibitors of recombinant human calpain I [1]

Journal of Medicinal Chemistry

Volumn 41, Issue 15, 1998, Pages 2663-2666

  Chatterjee, S ^a   Gu, Z Q ^a   Dunn, D ^a   Tao, M ^a   Josef, K ^a   Tripathy, R ^a   Bihovsky, R ^a   Senadhi, S E ^a   O'Kane, T M ^a   McKenna, B A ^a   Mallya, S ^a   Ator, M A ^a   Bozyczko Coyne, D ^a   Siman, R ^a   Mallamo, J P ^a  

^a CEPHALON INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM ION; CALPASTATIN; CATHEPSIN B; CHYMOTRYPSIN A; CYTOSKELETON PROTEIN; DEXTRO AMINO ACID; SPECTRIN; THROMBIN;

BINDING AFFINITY; CALCIUM CELL LEVEL; CONTROLLED STUDY; DRUG DESIGN; DRUG MECHANISM; DRUG PENETRATION; DRUG POTENCY; ENZYME INHIBITOR INTERACTION; ENZYME SPECIFICITY; HUMAN; HUMAN CELL; LETTER; LEUKEMIA CELL LINE; NERVE CELL DEGENERATION; PROTEIN DEGRADATION; PROTEINASE INHIBITION; STROKE;

AMINO ACIDS; BINDING SITES; CALPAIN; DIPEPTIDES; ENZYME INHIBITORS; HUMANS; KINETICS; RECOMBINANT PROTEINS; STEREOISOMERISM; SULFONAMIDES; TUMOR CELLS, CULTURED;

EID: 0031875208     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm980035y     Document Type: Letter

References (12)