Spectroscopic and kinetic studies of interactions of calf spleen purine nucleoside phosphorylase with 8-azaguanine, and its 9-(2-phosphonylmethoxyethyl) derivative

Nucleosides, Nucleotides and Nucleic Acids

Volumn 24, Issue 5-7, 2005, Pages 459-464

  Wierzchowski, Jacek ^a   Stȩpniak, Katarzyna ^b   Bzowska, Agnieszka ^b   Shugar, David ^b,c  

^a UNIVERSITY OF WARMIA AND MAZURY IN OLSZTYN   (Poland)

^b UNIVERSITY OF WARSAW   (Poland)

^c INSTITUTE OF BIOCHEMISTRY AND BIOPHYSICS   (Poland)

Author keywords

8 Azaguanine; Catalytic Mechanism; Enzyme Ligand Complexes; Fluorescence; Purine Nucleoside Phosphorylase

Indexed keywords

8 AZAGUANINE; 9 (2 PHOSPHONYLMETHOXYETHYL) 8 AZAGUANINE DERIVATIVE; GUANINE DERIVATIVE; PURINE NUCLEOSIDE PHOSPHORYLASE; PURINE NUCLEOSIDE PHOSPHORYLASE INHIBITOR; UNCLASSIFIED DRUG;

CATTLE; CHEMICAL REACTION KINETICS; CONFERENCE PAPER; ENZYME BINDING; ENZYME INHIBITOR INTERACTION; ENZYME MECHANISM; FLUORESCENCE; ION TRANSPORT; LIGAND BINDING; NONHUMAN; SPECTROSCOPY; SPLEEN;

ANIMALS; ANTIMETABOLITES, ANTINEOPLASTIC; AZAGUANINE; CATTLE; DRUG INTERACTIONS; HYDROGEN-ION CONCENTRATION; KINETICS; LIGANDS; MACROMOLECULAR SUBSTANCES; MODELS, CHEMICAL; PURINE-NUCLEOSIDE PHOSPHORYLASE; SPECTROMETRY, FLUORESCENCE; SPLEEN; SUBSTRATE SPECIFICITY;

BOS TAURUS;

EID: 26644434637     PISSN: 15257770     EISSN: 15322335     Source Type: Journal    
DOI: 10.1081/NCN-200060004     Document Type: Conference Paper

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