Alterations of 9p in squamous cell carcinoma and adenocarcinoma of the lung: Association with smoking, TP53, and survival

Cancer Genetics and Cytogenetics

Volumn 162, Issue 2, 2005, Pages 115-121

  Marsit, Carmen J ^a   Wiencke, John K ^b   Nelson, Heather H ^a   Kim, Duk Hwan ^c   Hinds, Philip W ^d   Aldape, Kenneth ^e   Kelsey, Karl T ^a  

^a HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c Samsung Medical Center   (South Korea)

^d TUFTS MEDICAL CENTER   (United States)

^e UNIVERSITY OF TEXAS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN P53; TOBACCO SMOKE;

ADULT; AGED; ARTICLE; CANCER PATIENT; CANCER SURGERY; CANCER SURVIVAL; CHEMICAL MUTAGENESIS; CHROMOSOME 9P; CONTROLLED STUDY; DEMOGRAPHY; ENVIRONMENTAL EXPOSURE; FEMALE; GENE DELETION; GENE INACTIVATION; GENE MUTATION; GENETIC ASSOCIATION; HETEROZYGOSITY LOSS; HOMOZYGOSITY; HUMAN; IMMUNOHISTOCHEMISTRY; LUNG ADENOCARCINOMA; MAJOR CLINICAL STUDY; MALE; MICROSATELLITE MARKER; PREDICTION; PRIORITY JOURNAL; SMOKING; SQUAMOUS CELL CARCINOMA; STAINING; SURVIVAL RATE;

ADENOCARCINOMA; AGED; CARCINOMA, SQUAMOUS CELL; CHROMOSOMES, HUMAN, PAIR 9; FEMALE; GENE DELETION; GENES, P53; HUMANS; LOSS OF HETEROZYGOSITY; LUNG NEOPLASMS; MALE; MULTIVARIATE ANALYSIS; SMOKING; SURVIVAL ANALYSIS; TIME FACTORS;

NICOTIANA TABACUM;

EID: 26444596500     PISSN: 01654608     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cancergencyto.2005.04.001     Document Type: Article

References (39)

1. IARC Tobacco Smoke and Involuntary Smoking. In: IARC monographs on the evaluation of carcinogenic risks to humans. Lyon, France: IARC press, 2004
2. A. Jemal, T. Murray, A. Samuels, A. Ghafoor, E. Ward, and M.J. Thun Cancer statistics, 2003 CA Cancer J Clin 53 2003 5 26
3. W.D. Flanders, C.A. Lally, B.P. Zhu, S.J. Henley, and M.J. Thun Lung cancer mortality in relation to age, duration of smoking, and daily cigarette consumption: results from Cancer Prevention Study II Cancer Res 63 2003 6556 6562
4. S. de Vos, C.W. Miller, S. Takeuchi, A.F. Gombart, S.K. Cho, and H.P. Koeffler Alterations of CDKN2 (p16) in non-small cell lung cancer Genes Chromosomes Cancer 14 1995 164 170
5. S. Sasaki, Y. Kitagawa, Y. Sekido, J.D. Minna, H. Kuwano, J. Yokota, and T. Kohno Molecular processes of chromosome 9p21 deletions in human cancers Oncogene 22 2003 3792 3798
6. G. Mariatos, V.G. Gorgoulis, P. Zacharatos, A. Kotsinas, T. Vogiatzi, G. Rassidakis, P. Foukas, T. Liloglou, D. Tiniakos, N. Angelou, E.N. Manolis, M. Veslemes, J.K. Field, and C. Kittas Expression of p16(INK4A) and alterations of the 9p21-23 chromosome region in non-small-cell lung carcinomas: relationship with tumor growth parameters and ploidy status Int J Cancer 89 2000 133 141
7. L.J. Mead, M.T. Gillespie, J.Y. Hung, U.S. Rane, K.C. Rayeroux, L.B. Irving, and L.J. Campbell Frequent loss of heterozygosity in early non-small cell lung cancers at chromosome 9p21 proximal to the CDKN2a gene Int J Cancer 71 1997 213 217
8. A. Merlo, E. Gabrielson, F. Askin, and D. Sidransky Frequent loss of chromosome 9 in human primary non-small cell lung cancer Cancer Res 54 1994 640 642
9. A. Merlo, E. Gabrielson, M. Mabry, R. Vollmer, S.B. Baylin, and D. Sidransky Homozygous deletion on chromosome 9p and loss of heterozygosity on 9q, 6p, and 6q in primary human small cell lung cancer Cancer Res 54 1994 2322 2326
10. Wistuba II, C. Behrens, S. Milchgrub, D. Bryant, J. Hung, J.D. Minna, and A.F. Gazdar Sequential molecular abnormalities are involved in the multistage development of squamous cell lung carcinoma Oncogene 18 1999 643 650
11. Y. Kishimoto, K. Sugio, T. Mitsudomi, T. Oyama, A.K. Virmani, D.D. McIntire, and A.F. Gazdar Frequent loss of the short arm of chromosome 9 in resected non-small-cell lung cancers from Japanese patients and its association with squamous cell carcinoma J Cancer Res Clin Oncol 121 1995 291 296
12. V.G. Gorgoulis, P. Zacharatos, A. Kotsinas, T. Liloglou, A. Kyroudi, M. Veslemes, A. Rassidakis, T.D. Halazonetis, J.K. Field, and C. Kittas Alterations of the p16-pRb pathway and the chromosome locus 9p21-22 in non-small-cell lung carcinomas: relationship with p53 and MDM2 protein expression Am J Pathol 153 1998 1749 1765
13. D.H. Kim, H.H. Nelson, J.K. Wiencke, S. Zheng, D.C. Christiani, J.C. Wain, E.J. Mark, and K.T. Kelsey p16(INK4a) and histology-specific methylation of CpG islands by exposure to tobacco smoke in non-small cell lung cancer Cancer Res 61 2001 3419 3424
14. W.A. Palmisano, K.P. Crume, M.J. Grimes, S.A. Winters, M. Toyota, M. Esteller, N. Joste, S.B. Baylin, and S.A. Belinsky Aberrant promoter methylation of the transcription factor genes PAX5 alpha and beta in human cancers Cancer Res 63 2003 4620 4625
15. L.J. Mead, M.T. Gillespie, L.B. Irving, and L.J. Campbell Homozygous and hemizygous deletions of 9p centromeric to the interferon genes in lung cancer Cancer Res 54 1994 2307 2309
16. J.S. Wiest, W.A. Franklin, J.T. Otstot, K. Forbey, M. Varella-Garcia, K. Rao, H. Drabkin, R. Gemmill, S. Ahrent, D. Sidransky, G. Saccomanno, J.W. Fountain, and M.W. Anderson Identification of a novel region of homozygous deletion on chromosome 9p in squamous cell carcinoma of the lung: the location of a putative tumor suppressor gene Cancer Res 57 1997 1 6
17. Y.E. Whang, X. Wu, and C.L. Sawyers Identification of a pseudogene that can masquerade as a mutant allele of the PTEN/MMAC1 tumor suppressor gene J Natl Cancer Inst 90 1998 859 861
18. D.H. Teng, R. Hu, H. Lin, T. Davis, D. Iliev, C. Frye, B. Swedlund, K.L. Hansen, V.L. Vinson, K.L. Gumpper, L. Ellis, A. El-Naggar, M. Frazier, S. Jasser, L.A. Langford, J. Lee, G.B. Mills, M.A. Pershouse, R.E. Pollack, C. Tornos, P. Troncoso, W.K. Yung, G. Fujii, A. Berson, and P.A. Steck MMAC1/PTEN mutations in primary tumor specimens and tumor cell lines Cancer Res 57 1997 5221 5225
19. P.L. Dahia, M.G. FitzGerald, X. Zhang, D.J. Marsh, Z. Zheng, T. Pietsch, A. von Deimling, F.G. Haluska, D.A. Haber, and C. Eng A highly conserved processed PTEN pseudogene is located on chromosome band 9p21 Oncogene 16 1998 2403 2406
20. M.A. Robinson, M.P. Mitchell, S. Wei, C.E. Day, T.M. Zhao, and P. Concannon Organization of human T-cell receptor beta-chain genes: clusters of V beta genes are present on chromosomes 7 and 9 Proc Natl Acad Sci USA 90 1993 2433 2437
21. H.H. Nelson, D.C. Christiani, E.J. Mark, J.K. Wiencke, J.C. Wain, and K.T. Kelsey Implications and prognostic value of K-ras mutation for early-stage lung cancer in women J Natl Cancer Inst 91 1999 2032 2038
22. H.H. Nelson, J.K. Wiencke, L. Gunn, J.C. Wain, D.C. Christiani, and K.T. Kelsey Chromosome 3p14 alterations in lung cancer: evidence that FHIT exon deletion is a target of tobacco carcinogens and asbestos Cancer Res 58 1998 1804 1807
23. M.L. Simmons, K.R. Lamborn, M. Takahashi, P. Chen, M.A. Israel, M.S. Berger, T. Godfrey, J. Nigro, M. Prados, S. Chang, F.G. Barker 2nd, and K. Aldape Analysis of complex relationships between age, p53, epidermal growth factor receptor, and survival in glioblastoma patients Cancer Res 61 2001 1122 1128
24. A. Jemal, T. Murray, E. Ward, A. Samuels, R.C. Tiwari, A. Ghafoor, E.J. Feuer, and M.J. Thun Cancer statistics, 2005 CA Cancer J Clin 55 2005 10 30
25. L.R. Livingstone, A. White, J. Sprouse, E. Livanos, T. Jacks, and T.D. Tlsty Altered cell cycle arrest and gene amplification potential accompany loss of wild-type p53 Cell 70 1992 923 935
26. K.L. Mekeel, W. Tang, L.A. Kachnic, C.M. Luo, J.S. DeFrank, and S.N. Powell Inactivation of p53 results in high rates of homologous recombination Oncogene 14 1997 1847 1857
27. Y. Yin, M.A. Tainsky, F.Z. Bischoff, L.C. Strong, and G.M. Wahl Wild-type p53 restores cell cycle control and inhibits gene amplification in cells with mutant p53 alleles Cell 70 1992 937 948
28. T. Hirao, H.H. Nelson, T.D. Ashok, J.C. Wain, E.J. Mark, D.C. Christiani, J.K. Wiencke, and K.T. Kelsey Tobacco smoke-induced DNA damage and an early age of smoking initiation induce chromosome loss at 3p21 in lung cancer Cancer Res 61 2001 612 615
29. J.K. Wiencke, S.W. Thurston, K.T. Kelsey, A. Varkonyi, J.C. Wain, E.J. Mark, and D.C. Christiani Early age at smoking initiation and tobacco carcinogen DNA damage in the lung J Natl Cancer Inst 91 1999 614 619
30. W.P. Bennett p53 alterations in progenitor lesions of the bronchus, esophagus, oral cavity, and colon Cancer Detect Prev 19 1995 503 511
31. W.P. Bennett, T.V. Colby, W.D. Travis, A. Borkowski, R.T. Jones, D.P. Lane, R.A. Metcalf, J.M. Samet, Y. Takeshima, and J.R. Gu p53 protein accumulates frequently in early bronchial neoplasia Cancer Res 53 1993 4817 4822
32. A. Burkle Mechanisms of ageing Eye 15 2001 371 375
33. C.J. Marsit, M. Hasegawa, T. Hirao, D. Kim, K. Aldape, P.W. Hinds, J.K. Wiencke, H.H. Nelson, and K.T. Kelsey Loss of heterozygosity of chromosome 3p21 is associated with mutant TP53 and better patient survival in non-small cell lung cancer Canc Res 64 2004 8702 8707
34. C. Mondello, M. Chiesa, P. Rebuzzini, S. Zongaro, A. Verri, T. Colombo, E. Giulotto, M. D'Incalci, C. Franceschi, and F. Nuzzo Karyotype instability and anchorage-independent growth in telomerase-immortalized fibroblasts from two centenarian individuals Biochem Biophys Res Commun 308 2003 914 921
35. A. Seluanov, D. Mittelman, O.M. Pereira-Smith, J.H. Wilson, and V. Gorbunova DNA end joining becomes less efficient and more error-prone during cellular senescence Proc Natl Acad Sci USA 101 2004 7624 7629
36. S. Zienolddiny, D. Ryberg, M.O. Arab, V. Skaug, and A. Haugen Loss of heterozygosity is related to p53 mutations and smoking in lung cancer Br J Cancer 84 2001 226 231
37. A.J. Mighell, N.R. Smith, P.A. Robinson, and A.F. Markham Vertebrate pseudogenes FEBS Lett 468 2000 109 114
38. J.K. Wiencke, and K.T. Kelsey Teen smoking, field cancerization, and a "critical period" hypothesis for lung cancer susceptibility Environ Health Perspect 110 2002 555 558
39. Marsit CJ, Hasegawa M, Hirao T, Kim D, Aldape K, Hinds PW, Wiencke JK, Nelson HH, Kelsey KT. Loss of heterozygosity of chromosome 3p21 is associated with mutant TP53 and better patient survival in non-small cell lung cancer. Canc Res 2004, in press.