Expression and immunogenicity of an Escherichia coli K99 fimbriae subunit antigen in soybean

Planta

Volumn 222, Issue 1, 2005, Pages 6-18

  Piller, Kenneth J ^a   Clemente, Thomas E ^b   Jun, Sang Mu ^c   Petty, Cynthia C ^a   Sato, Shirley ^b   Pascual, David W ^c   Bost, Kenneth L ^a  

^a UNIVERSITY OF NORTH CAROLINA AT CHARLOTTE   (United States)

^b UNIVERSITY OF NEBRASKA LINCOLN   (United States)

^c MONTANA STATE UNIVERSITY   (United States)

Author keywords

Edible vaccine; Enterotoxigenic Escherichia coli; FanC; K99; Transgenic soybean

Indexed keywords

ANTIBODIES; IMMUNOLOGY; POLYPEPTIDES; PROTEINS; VACCINES;

EDIBLE VACCINE; ENTEROTOXIGENIC ESCHERICHIA COLI (ETEC); FANC; K99; TRANSGENIC SOYBEAN;

ESCHERICHIA COLI;

BACTERIAL ANTIGEN; BACTERIAL TOXIN; BACTERIAL VACCINE; BACTERIUM ANTIBODY; K99 ANTIGEN; MEMBRANE ANTIGEN;

ANIMAL; ARTICLE; BLOOD; CD4+ T LYMPHOCYTE; CLASSIFICATION; ENTEROBACTER INFECTION; ESCHERICHIA COLI; GENE EXPRESSION; GENETICS; IMMUNOLOGY; METABOLISM; MOUSE; NUCLEOTIDE SEQUENCE; PATHOGENICITY; SOYBEAN; TRANSGENE; TRANSGENIC PLANT; VACCINATION;

ANIMALS; ANTIBODIES, BACTERIAL; ANTIGENS, BACTERIAL; ANTIGENS, SURFACE; BACTERIAL TOXINS; BACTERIAL VACCINES; BASE SEQUENCE; CD4-POSITIVE T-LYMPHOCYTES; ESCHERICHIA COLI; ESCHERICHIA COLI INFECTIONS; GENE EXPRESSION; MICE; PLANTS, GENETICALLY MODIFIED; SOYBEANS; TRANSGENES; VACCINATION;

ANTIBODIES; BACTERIOLOGY; INOCULATION; PEPTIDES; PROTEINS;

AGROBACTERIUM; ANIMALIA; BOS TAURUS; ESCHERICHIA COLI; GLYCINE MAX; RHIZOBIUM;

EID: 26444581691     PISSN: 00320935     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00425-004-1445-9     Document Type: Article

References (37)

1. Ascon MA, Hone DM, Walters N, Pascual DW (1998) Oral immunization with a Salmonella typhimurium vaccine vector expressing recombinant enterotoxigenic Escherichia coli K99 fimbriae elicits elevated antibody titers for protective immunity. Infect Immun 66:5470-5476
2. Carrington JC, Freed DD (1990) Cap-independent enhancement of translation by a plant potyvirus 5′ nontranslated region. J Virol 64:1590-1597
3. Clarke SC (2001) Diarrhoeagenic Escherichia coli - an emerging problem? Diagn Microbiol Infect Dis 41:93-98
4. Clemente TE, LaVallee BJ, Howe AR, Conner-Ward D, Rozman R, Hunter P, Broyles DL, Kasten D, Hinchee MA (2000) Progeny analysis of glyphosate selected transgenic soybeans derived from Agrobacterium-mediated transformation. Crop Sci 40:797-803
5. Daniell H, Streatfield SJ, Wycoff K (2001) Medical molecular farming: production of antibodies, biopharmaceuticals and edible vaccines in plants. Trends Plant Sci 6:219-226
6. Ditta G, Stanfield S, Corbin D, Helinski DR (1980) Broad host range DNA cloning system for gram-negative bacteria: construction of a gene bank of Rhizobium meliloti. Proc Natl Acad Sci USA 77:7347-7351
7. Dus Santos MJ, Wigdorovitz A, Trono K, Rios RD, Franzone PM, Gil F, Moreno J, Carrillo C, Escribano JM, Borca MV (2002) A novel methodology to develop a foot and mouth disease virus (FMDV) peptide-based vaccine in transgenic plants. Vaccine 20:1141-1147
8. Elhofy A, Marriott I, Bost KL (2000) Salmonella infection does not increase expression and activity of the high affinity IL-12 receptor. J Immunol 165:3324-3332
9. Embden JD van, de Graaf FK, Schouls LM, Teppema JS (1980) Cloning and expression of a deoxyribonucleic acid fragment that encodes for the adhesive antigen K99. Infect Immun 29:1125-1133
10. Gallie DR, Tanguay RL, Leathers V (1995) The tobacco etch viral 5′ leader and poly(A) tail are functionally synergistic regulators of translation. Gene 165:233-238
11. de Graaf FK, Klemm P, Gaastra W (1981) Purification, characterization, and partial covalent structure of Escherichia coli adhesive antigen K99. Infect Immun 33:877-883
12. de Graaf FK, Krenn BE, Klaasen P (1984) Organization and expression of genes involved in the biosynthesis of K99 fimbriae. Infect Immun 43: 508-514
13. Hajdukiewicz P, Svab Z, Maliga P (1994) The small, versatile pPZP family of Agrobacterium binary vectors for plant transformation. Plant Mol Biol 25:989-994
14. Hood EE, Helmer GL, Fraley RT, Chilton MD (1986) The hypervirulence of Agrobacterium tumefaciens A281 is encoded in a region of pTiBo542 outside of T-DNA. J Bacteriol 168:1291-1301
15. Inoue OJ, Lee JH, Isaacson RE (1993) Transcriptional organization of the Escherichia coli pilus adhesin K99. Mol Microbiol 10:607-613
16. Isaacson RE, Start GL (1992) Analysis of K99 plasmids from enterotoxigenic Escherichia coli. FEMS Microbiol Lett 69:141-146
17. Jones GW, Isaacson RE (1983) Proteinaceous bacterial adhesins and their receptors. Crit Rev Microbiol 10:229-260
18. Khandelwal A, Renukaradhya GJ, Rajasekhar M, Sita GL, Shaila MS (2004) Systemic and oral immunogenicity of hemagglutinin protein of rinderpest virus expressed by transgenic peanut plants in a mouse model. Virology 323:284-291
19. Lee JH, Isaacson RE (1995) Expression of the gene cluster associated with the Escherichia coli pilus adhesin K99. Infect Immun 63:4143-4149
20. Lee RW, Strommer J, Hodgins D, Shewen PE, Niu Y, Lo RY (2001) Towards development of an edible vaccine against bovine pneumonic pasteurellosis using transgenic white clover expressing a Mannheimia haemolytica A1 leukotoxin 50 fusion protein. Infect Immun 69:5786-5793
21. Nagy B, Fekete PZ (1999) Enterotoxigenic Escherichia coli (ETEC) in farm animals. Vet Res 30:259-284
22. Ogunniyi AD, Kotlarski I, Morona R, Manning PA (2002) Epitope analysis of the FanC subunit protein of the K99 (F5) fimbriae of enterotoxigenic Escherichia coli using a recombinant fusion technique. FEMS Immunol Med Microbiol 34:23-31
23. Peacock JW, Bost KL (2001) Murine gammaherpesvirus-68-induced interleukin-10 increases viral burden, but limits virus-induced splenomegaly and leukocytosis. Immunology 104:109-117
24. Roosendaal B, Gaastra W, de Graaf FK (1984) The nucleotide sequence of the gene encoding the K99 subunit of enterotoxigenic Escherichia coli. FEMS Microbiol Lett 22:253-258
25. Roosendaal B, Damoiseaux J, Jordi W, de Graaf FK (1989) Transcriptional organization of the DNA region controlling expression of the K99 gene cluster. Mol Gen Genet 215:250-256
26. Sato S, Xing A, Ye X, Schweiger B, Kinney A, Graef G, Clemente T (2004) Production of gamma-linolenic acid and stearidonic acid in seeds of marker-free transgenic soybean. Crop Sci 44:646-652
27. Simons BL, Rathman P, Malij CR, Oudega B, de Graaf FK (1990) The penultimate tyrosine residue of the K99 fibrillar subunit is essential for stability of the protein and its interaction with the periplasmic carrier protein. FEMS Microbiol Lett 55:107-112
28. Son YI, Egawa S, Tatsumi T, Redlinger RE, Jr, Kalinski P, Kanto T (2002) A novel bulk-culture method for generating mature dendritic cells from mouse bone marrow cells. J Immunol Methods 262:145-157
29. Steinsland H, Valentiner-Branth P, Gjessing HK, Aaby P, Molbak K, Sommerfelt H (2003) Protection from natural infections with enterotoxigenic Escherichia coli: longitudinal study. Lancet 362:286-291
30. Streatfield SJ, Jilka JM, Hood EE, Turner DD, Bailey MR, Mayor JM, Woodard SL, Beifuss KK, Horn ME, Delaney DE, Tizard IR, Howard JA (2001) Plant-based vaccines: unique advantages. Vaccine 19:2742-2748
31. Tacket CO, Pasetti MF, Edelman R, Howard JA, Streatfield S (2004) Immunogenicity of recombinant LT-B delivered orally to humans in transgenic corn. Vaccine 22:4385-4389
32. Thanavala Y, Yang YF, Lyons P, Mason HS, Arntzen C (1995) Immunogenicity of transgenic plant-derived hepatitis B surface antigen. Proc Natl Acad Sci USA 92:3358-3361
33. Thompson CJ, Movva NR, Tizard R, Crameri R, Davies JE, Lauwereys M, Botterman J (1987) Characterization of the herbicide-resistance gene bar from Streptomyces hygroscopicus. EMBO J 6:2519-2523
34. Tuboly T, Yu W, Bailey A, Degrandis S, Du S, Erickson L, Nagy E (2000) Immunogenicity of porcine transmissible gastroenteritis virus spike protein expressed in plants. Vaccine 18:2023-2028
35. Wigdorovitz A, Carrillo C, Dus Santos MJ, Trono K, Peralta A, Gomez MC, Rios RD, Franzone PM, Sadir AM, Escribano JM, Borca MV (1999) Induction of a protective antibody response to foot and mouth disease virus in mice following oral or parenteral immunization with alfalfa transgenic plants expressing the viral structural protein VP1. Virology 255:347-353
36. Wigdorovitz A, Mozgovoj M, Santos MJ, Parreno V, Gomez C, Perez-Filgueira DM, Trono KG, Rios RD, Franzone PM, Fernandez F, Carrillo C, Babiuk LA, Escribano JM, Borca MV (2004) Protective lactogenic immunity conferred by an edible peptide vaccine to bovine rotavirus produced in transgenic plants. J Gen Virol 85:1825-1832
37. Zhang Z, Xing A, Staswick PE, Clemente TE (1999) The use of glufosinate as a selective agent in Agrobacterium-mediated transformation of soybean. Plant Cell Tissue Organ Cult 56:37-46