Detection of very high-level penicillin-resistant variants of the Tennessee 23F-4 clone via single and serial transformations with four serotype 19A international pneumococcal clones

Microbial Drug Resistance

Volumn 11, Issue 3, 2005, Pages 271-278

  McEllistrem, M Catherine ^a   Adams, Jennifer M ^a   Visweswaran, Shyam ^b   Khan, Saleem A ^a  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF PITTSBURGH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTIC AGENT; CEFOTAXIME; DNA; PENICILLIN DERIVATIVE;

ALIA GENE; ANTIBIOTIC RESISTANCE; AROE GENE; ARTICLE; BACTERIAL GENE; CONTROLLED STUDY; DDL GENE; DEXB GENE; GDH GENE; GENETIC RECOMBINATION; GKI GENE; HOUSEKEEPING GENE; MINIMUM INHIBITORY CONCENTRATION; MULTILOCUS SEQUENCE TYPING; NONHUMAN; NUCLEOTIDE SEQUENCE; PBP1A GENE; PBP2B GENE; PBP2X GENE; PENICILLIN RESISTANCE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PULSED FIELD GEL ELECTROPHORESIS; RECP GENE; SEROTYPE; SPI GENE; STRAIN DIFFERENCE; STREPTOCOCCUS PNEUMONIAE; XPT GENE;

ALLELES; BACTERIAL TYPING TECHNIQUES; MICROBIAL SENSITIVITY TESTS; PENICILLIN RESISTANCE; PENICILLINS; PNEUMOCOCCAL INFECTIONS; PNEUMOCOCCAL VACCINES; SEROTYPING; STREPTOCOCCUS PNEUMONIAE; TENNESSEE;

STREPTOCOCCUS;

EID: 26444558158     PISSN: 10766294     EISSN: None     Source Type: Journal    
DOI: 10.1089/mdr.2005.11.271     Document Type: Article

References (33)

1. National Committee for Clinical Laboratory Standards. 2004. Performance standards for antimicrobial susceptibility testing. Document no. NCCLS M100-S14. National Committee for Clinical Laboratory Standards, Wayne, PA.
2. Beall, B., G. Gherardi, R.R. Facklam, and S.K. Hollingshead. 2000. Pneumococcal pspA sequence types of prevalent multiresistant pneumococcal strains in the United States and of internationally disseminated clones. J. Clin. Microbiol. 38:3663-3669.
3. Coffey, T.J., M. Daniels, M.C. Enright, and B.C. Spratt. 1999. Serotype 14 variants of the Spanish penicillin-resistant serotype 9V clone of Streptococcus pneumoniae arose by large recombinational replacements of the cpsA-pbpla region. Microbiology 145(Pt 8):2023-2031.
4. Coffey, T.J., M. Daniels, L.K. McDougal, C.G. Dowson, F.C. Tenover, and B.G. Spratt. 1995. Genetic analysis of clinical isolates of Streptococcus pneumoniae with high-level resistance to expanded-spectrum cephalosporins. Antimicrob. Agents Chemother. 39:1306-1313.
5. Coffey, T.J., C.G. Dowson, M. Daniels, and B.C. Spratt. 1995. Genetics and molecular biology of beta-lactam-resistant pneumococci. Microb. Drug Resist. 1:29-34.
6. Coffey, T.J., M.C. Enright, M. Daniels, J.K. Morona, R. Morona, W. Hryniewicz, J.C. Paton, and B.C. Spratt. 1998. Recombinational exchanges at the capsular polysaccharide biosynthetic locus lead to frequent serotype changes among natural isolates of Streptococcus pneumoniae. Mol. Microbiol. 27:73-83.
7. Dowson, C.G., A. Hutchison, J.A. Brannigan, R.C. George, D. Hansman, J. Linares, A. Tomasz, J.M. Smith, and B.G. Spratt. 1989. Horizontal transfer of penicillin-binding protein genes in penicillin-resistant clinical isolates of Streptococcus pneumoniae. Proc. Natl. Acad. Sci. USA 86:8842-8846.
8. du Plessis, M., A.M. Smith, and K.P. Klugman. 1998. Rapid detection of penicillin-resistant Streptococcus pneumoniae in cerebrospinal fluid by a seminested-PCR strategy. J. Clin. Microbiol. 36:453-457.
9. Enright, M.C., and B.G. Spratt. 1999. Extensive variation in the ddl gene of penicillin-resistant Streptococcus pneumoniae results from a hitchhiking effect driven by the penicillin-binding protein 2b gene. Mol. Biol. Evol. 16:1687-1695.
10. Gertz, R.E., Jr., M.C. McEllistrem, D.J. Boxrud, Z. Li, V. Sakota, T.A. Thompson, R.R. Facklam, J.M. Besser, L.H. Harrison, C.G. Whitney, and B. Beall. 2003. Clonal distribution of invasive pneumococcal isolates from children and selected adults in the United States prior to 7-valent conjugate vaccine introduction. J. Clin. Microbiol. 41:4194-4216.
11. Gherardi, G., C.G. Whitney, R.R. Facklam, and B. Beall. 2000. Major related sets of antibiotic-resistant Pneumococci in the United States as determined by pulsed-field gel electrophoresis and pbp1a-pbp2b-pbp2x-dhf restriction profiles. J. Infect. Dis. 181:216-229.
12. Havarstein, L.S., G. Coomaraswamy, and D.A. Morrison. 1995. An unmodified heptadecapeptide pheromone induces competence for genetic transformation in Streptococcus pneumoniae. Proc. Natl. Acad. Sci. USA 92:11140-11144.
13. Hollingshead, S.K., R. Becker, and D.E. Briles. 2000. Diversity of PspA: mosaic genes and evidence for past recombination in Streptococcus pneumoniae. Infect. Immun. 68:5889-5900.
14. Hoskins, J., W.E. Alborn, Jr., J. Arnold, L.C. Blaszczak, S. Burgett, B.S. DeHoff, S.T. Estrem, L. Fritz, D.J. Fu, W. Fuller, C. Geringer, R. Gilmour, J.S. Glass, H. Khoja, A.R. Kraft, R.E. Lagace, D.J. LeBlanc, L.N. Lee, E.J. Lefkowitz, J. Lu, P. Matsushima, S.M. McAhren, M. McHenney, K. McLeaster, C.W. Mundy, T.I. Nicas, F.H. Norris, M. O'Gara, R.B. Peery, G.T. Robertson, P. Rockey, P.M. Sun, M.E. Winkler, Y. Yang, M. Young-Bellido, G. Zhao, C.A. Zook, R.H. Baltz, S.R. Jaskunas, P.R. Rosteck, Jr., P.L. Skatrud, and J.I. Glass. 2001. Genome of the bacterium Streptococcus pneumoniae strain R6. J. Bacteriol. 183:5709-5717.
15. Laible, G., B.G. Spratt, and R. Hakenbeck. 1991. Interspecies recombinational events during the evolution of altered PBP 2x genes in penicillin-resistant clinical isolates of Streptococcus pneumoniae. Mol. Microbiol. 5:1993-2002.
16. McEllistrem, M.C., J. Adams, E.G. Mason, and E.R. Wald. 2003. Epidemiology of acute otitis media caused by Streptococcus pneumoniae before and after licensure of the 7-valent pneumococcal protein conjugate vaccine. J. Infect. Dis. 188:1679-1684.
17. McEllistrem, M.C., A.C. Noller, S. Visweswaran, J.M. Adams, and L.H. Harrison. 2004. Serotype 14 variants of the France 9V(-3) clone from Baltimore, Maryland, can be differentiated by the cpsB gene. J. Clin. Microbiol. 42:250-256.
18. McEllistrem, M.C., M. Pass, J.A. Elliott, C.G. Whitney, and L.H. Harrison. 2000. Clonal groups of penicillin-nonsusceptible Streptococcus pneumoniae in Baltimore, Maryland: a population-based, molecular epidermiologic study. J. Clin. Microbiol. 38:4367-4372.
19. McEllistrem, M.C., J.M. Adams, K. Patel, A.B. Mendelsohn, S.L. Kaplan, J.S. Bradley, G.E. Schutze, K.S. Kim, E.O. Mason, and E.R. Wald. 2005. Acute otitis media due to penicillin non-susceptible Streptococcus pneumoniae before and after the introduction of the pneumococcal conjugate vaccine. Clin. Infect. Dis. 40:1738-1744.
20. McGee, L., L. McDougal, J. Zhou, B.C. Spratt, F.C. Tenover, R. George, R. Hakenbeck, W. Hryniewicz, J.C. Lefevre, A. Tomasz, and K.P. Klugman. 2001. Nomenclature of major antimicrobial-resistant clones of Streptococcus pneumoniae defined by the pneumococcal molecular epidemiology network. J. Clin. Microbiol. 39:2565-2571.
21. Morona, J.K., D.C. Miller, T.J. Coffey, C.J. Vindurampulle, B.C. Spratt, R. Morona, and J.C. Paton. 1999. Molecular and genetic characterization of the capsule biosynthesis locus of Streptococcus pneumoniae type 23F. Microbiology 145(Pt 4):781-789.
22. Morona, J.K., R. Morona, and J.C. Paton. 1997. Characterization of the locus encoding the Streptococcus pneumoniae type 19F capsular polysaccharide biosynthetic pathway. Mol. Microbiol. 23:751-763.
23. Morrison, D.A., S.A. Lacks, W.R. Guild, and J.M. Hageman. 1983. Isolation and characterization of three new classes of transformation-deficient mutants of Streptococcus pneumoniae that are defective in DNA transport and genetic recombination. J. Bacteriol. 156:281-290.
24. Morrison, K.E., D. Lake, J. Crook, G.M. Carlone, E. Ades, R. Facklam, and J.S. Sampson. 2000. Confirmation of psaA in all 90 serotypes of Streptococcus pneumoniae by PCR and potential of this assay for identification and diagnosis. J. Clin. Microbiol. 38:434-437.
25. Pozzi, G., L. Masala, F. Iannelli, R. Manganelli, L.S. Havarstein, L. Piccoli, D. Simon, and D.A. Morrison. 1996. Competence for genetic transformation in encapsulated strains of Streptococcus pneumoniae: two allelic variants of the peptide pheromone. J. Bacteriol. 178:6087-6090.
26. Schrag, S.J., L. McGee, C.G. Whitney, B. Beall, A.S. Craig, M.E. Choate, J.H. Jorgensen, R.R. Facklam, and K.P. Klugman. 2004. Emergence of Streptococcus pneumoniae with very-high-level resistance to penicillin. Antimicrob. Agents Chemother. 48:3016-3023.
27. Smith, A.M., and K.P. Klugman. 1995. Alterations in penicillin-binding protein 2B from penicillin-resistant wild-type strains of Streptococcus pneumoniae. Antimicrob. Agents Chemother. 39:859-867.
28. Smith, A.M., and K.P. Klugman. 1998. Alterations in PBP 1A essential-for high-level penicillin resistance in Streptococcus pneumoniae. Antimicrob. Agents Chemother. 42:1329-1333.
29. Smith, A.M., and K.P. Klugman. 2003. Site-specific mutagenesis analysis of PBP 1A from a penicillin-cephalosporin-resistant pneumococcal isolate. Antimicrob. Agents Chemother. 47:387-389.
30. Tart, R.C., L.S. McDaniel, B.A. Ralph, and D.E. Briles. 1996. Truncated Streptococcus pneumoniae PspA molecules elicit cross-protective immunity against pneumococcal challenge in mice. J. Infect. Dis. 173:380-386.
31. Tenover, F.C., R.D. Arbeit, R.V. Goering, P.A. Mickelsen, B.E. Murray, D.H. Persing, and B. Swaminathan. 1995. Interpreting chromosomal DNA restriction patterns produced by pulsed-field gel electrophoresis: criteria for bacterial strain typing. J. Clin. Microbiol. 33:2233-2239.
32. Trzcinski, K., C.M. Thompson, and M. Lipsitch. 2004. Single-step capsular transformation and acquisition of penicillin resistance in Streptococcus pneumoniae. J. Bacteriol. 186:3447-3452.
33. Whitney, C.G., M.M. Parley, J. Hadler, L.H. Harrison, N.M. Bennett, R. Lynfield, A. Reingold, P.R. Cieslak, T. Pilishvili, D. Jackson, R. R. Facklam, J.H. Jorgensen, and A. Schuchat. 2003. Decline in invasive pneumococcal disease after the introduction of protein-polysaccharide conjugate vaccine. N. Engl. J. Med. 348:1737-1746.