Characterization of genomic instability in ulcerative colitis neoplasia leads to discovery of putative tumor suppressor regions

Cancer Genetics and Cytogenetics

Volumn 162, Issue 2, 2005, Pages 99-106

  Chen, Ru ^a   Bronner, Mary P ^b   Crispin, David A ^a   Rabinovitch, Peter S ^a   Brentnall, Teresa A ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

^b LERNER RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CHROMOSOME 2Q; CHROMOSOME 6Q; COLON CARCINOMA; CONTROLLED STUDY; DNA FINGERPRINTING; DNA SEQUENCE; EPITHELIUM DYSPLASIA; GENE DELETION; GENE FREQUENCY; GENE INSERTION SEQUENCE; GENE LOSS; GENE SEQUENCE; GENETIC ANALYSIS; GENETIC SUSCEPTIBILITY; GENOMIC INSTABILITY; HETEROZYGOSITY LOSS; HUMAN; HUMAN TISSUE; MUTATIONAL ANALYSIS; OVARY CARCINOMA; POLYMERASE CHAIN REACTION; PRECANCER; PRIORITY JOURNAL; PROSTATE CARCINOMA; REAL TIME POLYMERASE CHAIN REACTION; REPRODUCIBILITY; TUMOR BIOPSY; TUMOR SUPPRESSOR GENE; ULCERATIVE COLITIS; VALIDATION PROCESS;

COLITIS, ULCERATIVE; COLORECTAL NEOPLASMS; DNA FINGERPRINTING; GENES, TUMOR SUPPRESSOR; GENOMIC INSTABILITY; HUMANS; LOSS OF HETEROZYGOSITY; MUTATION; POLYMERASE CHAIN REACTION; REPETITIVE SEQUENCES, NUCLEIC ACID;

EID: 26444514901     PISSN: 01654608     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cancergencyto.2005.04.006     Document Type: Article

References (33)

1. P.C. Nowell The clonal evolution of tumor cell populations Science 194 1976 23 28
2. D.L. Stoler, N. Chen, M. Basik, M.S. Kahlenberg, M.A. Rodriguez-Bigas, N.J. Petrelli, and G.R. Anderson The onset and extent of genomic instability in sporadic colorectal tumor progression Proc.Natl.Acad.Sci.USA 96 1999 15121 15126
3. K.R. Loeb, and L.A. Loeb Significance of multiple mutations in cancer Carcinogenesis 21 2000 379 385
4. A. Ekbom, C. Helmick, M. Zack, and H.O. Adami Ulcerative colitis and colorectal cancer. A population-based study N.Engl.J.Med 323 1990 1228 1233
5. R.H. Riddell, H. Goldman, D.F. Ransohoff, H.D. Appelman, C.M. Fenoglio, R.C. Haggitt, C. Ahren, P. Correa, S.R. Hamilton, and B.C. Morson Dysplasia in inflammatory bowel disease: standardized classification with provisional clinical applications Hum. Pathol 14 1983 931 968
6. P.S. Rabinovitch, S. Dziadon, T.A. Brentnall, M.J. Emond, D.A. Crispin, R.C. Haggitt, and M.P. Bronner Pancolonic chromosomal instability precedes dysplasia and cancer in ulcerative colitis Cancer Res 59 1999 5148 5153
7. R.F. Willenbucher, D.E. Aust, C.G. Chang, S.J. Zelman, L.D. Ferrell, D.H. Moore, and F.M. Waldman Genomic instability is an early event during the progression pathway of ulcerative-colitis-related neoplasia Am.J.Pathol 154 1999 1825 1830
8. M. Basik, D.L. Stoler, K.C. Kontzoglou, M.A. Rodriguez-Bigas, N.J. Petrelli, and G.R. Anderson Genomic instability in sporadic colorectal cancer quantitated by inter-simple sequence repeat PCR analysis Genes Chromosomes Cancer 18 1997 19 29
9. E. Zietkiewicz, A. Rafalski, and D. Labuda Genome fingerprinting by simple sequence repeat (SSR)-anchored polymerase chain reaction amplification Genomics 20 1994 176 183
10. J. Welsh, and M. McClelland Fingerprinting genomes using PCR with arbitrary primers Nucleic Acids Res 18 1990 7213 7218
11. J.G. Williams, A.R. Kubelik, K.J. Livak, J.A. Rafalski, and S.V. Tingey DNA polymorphisms amplified by arbitrary primers are useful as genetic markers Nucleic Acids Res 18 1990 6531 6535
12. R. Chen, P.S. Rabinovitch, D.A. Crispin, M.J. Emond, K.M. Koprowicz, M.P. Bronner, and T.A. Brentnall DNA fingerprinting abnormalities can distinguish ulcerative colitis patients with dysplasia and cancer from those who are dysplasia/cancer-free Am.J.Pathol 162 2003 665 672
13. S. Malkhosyan, J. Yasuda, J.L. Soto, T. Sekiya, J. Yokota, and M. Perucho Molecular karyotype (amplotype) of metastatic colorectal cancer by unbiased arbitrarily primed PCR DNA fingerprinting Proc.Natl.Acad.Sci.USA 95 1998 10170 10175
14. D.G. Ginzinger, T.E. Godfrey, J. Nigro, D.H. Moore, S. Suzuki, M.G. Pallavicini, J.W. Gray, and R.H. Jensen Measurement of DNA copy number at microsatellite loci using quantitative PCR analysis Cancer Res 60 2000 5405 5409
15. R.F. Willenbucher, S.J. Zelman, L.D. Ferrell, D.H. Moore, and F.M. Waldman Chromosomal alterations in ulcerative colitis-related neoplastic progression Gastroenterology 113 1997 791 801
16. L. Cawkwell, S.M. Bell, F.A. Lewis, M.F. Dixon, G.R. Taylor, and P. Quirke Rapid detection of allele loss in colorectal tumours using microsatellites and fluorescent DNA technology Br.J.Cancer 67 1993 1262 1267
17. S.P. Hussain, P. Amstad, K. Raja, S. Ambs, M. Nagashima, W.P. Bennett, P.G. Shields, A.J. Ham, J.A. Swenberg, A.J. Marrogi, and C.C. Harris Increased p53 mutation load in noncancerous colon tissue from ulcerative colitis: a cancer-prone chronic inflammatory disease Cancer Res 60 2000 3333 3337
18. W. Cliby, S. Ritland, L. Hartmann, M. Dodson, K.C. Halling, G. Keeney, K.C. Podratz, and R.B. Jenkins Human epithelial ovarian cancer allelotype Cancer Res 53 1993 2393 2398
19. I.E. Cooke, A.N. Shelling, V.G. Le Meuth, M.L. Charnock, and T.S. Ganesan Allele loss on chromosome arm 6q and fine mapping of the region at 6q27 in epithelial ovarian cancer Genes Chromosomes. Cancer 15 1996 223 233
20. M.A. Lastowska, D.M. Lillington, A.N. Shelling, I. Cooke, B. Gibbons, B.D. Young, and T.S. Ganesan Fluorescence in situ hybridization analysis using cosmid probes to define chromosome 6q abnormalities in ovarian carcinoma cell lines Cancer Genet.Cytogenet 77 1994 99 105
21. H. Lin, and P.J. Morin A novel homozygous deletion at chromosomal band 6q27 in an ovarian cancer cell line delineates the position of a putative tumor suppressor gene Cancer Lett 173 2001 63 70
22. S. Saito, H. Saito, S. Koi, S. Sagae, R. Kudo, J. Saito, K. Noda, and Y. Nakamura Fine-scale deletion mapping of the distal long arm of chromosome 6 in 70 human ovarian cancers Cancer Res 52 1992 5815 5817
23. M. Suzuki, S. Saito, Y. Saga, M. Ohwada, and I. Sato Loss of heterozygosity on chromosome 6q27 and p53 mutations in epithelial ovarian cancer Med.Oncol 15 1998 119 123
24. M.G. Tibiletti, B. Bernasconi, D. Furlan, P. Bressan, R. Cerutti, C. Facco, M. Franchi, C. Riva, R. Cinquetti, C. Capella, and R. Taramelli Chromosome 6 abnormalities in ovarian surface epithelial tumors of borderline malignancy suggest a genetic continuum in the progression model of ovarian neoplasms Clin.Cancer Res 7 2001 3404 3409
25. F. Gualandi, C. Morelli, J.V. Pavan, P. Rimessi, A. Sensi, A. Bonfatti, R. Gruppioni, L. Possati, E.J. Stanbridge, and G. Barbanti-Brodano Induction of senescence and control of tumorigenicity in BK virus transformed mouse cells by human chromosome 6 Genes Chromosomes.Cancer 10 1994 77 84
26. S. Saito, S. Sirahama, M. Matsushima, M. Suzuki, S. Sagae, R. Kudo, J. Saito, K. Noda, and Y. Nakamura Definition of a commonly deleted region in ovarian cancers to a 300-kb segment of chromosome 6q27 Cancer Res 56 1996 5586 5589
27. M.G. Tibiletti, B. Bernasconi, D. Furlan, C. Riva, M. Trubia, G. Buraggi, M. Franchi, P. Bolis, A. Mariani, L. Frigerio, C. Capella, and R. Taramelli Early involvement of 6q in surface epithelial ovarian tumors Cancer Res 56 1996 4493 4498
28. M.G. Tibiletti, M. Trubia, E. Ponti, L. Sessa, F. Acquati, D. Furlan, B. Bernasconi, M. Fichera, A. Mihalich, A. Ziegler, A. Volz, C. Facco, C. Riva, L. Cremonesi, M. Ferrari, and R. Taramelli Physical map of the D6S149-D6S193 region on chromosome 6q27 and its involvement in benign surface epithelial ovarian tumours Oncogene 16 1998 1639 1642
29. T. Ezaki, M. Watanabe, N. Inoue, T. Kanai, H. Ogata, Y. Iwao, H. Ishii, and T. Hibi A specific genetic alteration on chromosome 6 in ulcerative colitis-associated colorectal cancers Cancer Res 63 2003 3747 3749
30. M.L. Cher, G.S. Bova, D.H. Moore, E.J. Small, P.R. Carroll, S.S. Pin, J.I. Epstein, W.B. Isaacs, and R.H. Jensen Genetic alterations in untreated metastases and androgen-independent prostate cancer detected by comparative genomic hybridization and allelotyping Cancer Res 56 1996 3091 3102
31. D.P. Cahill, C. Lengauer, J. Yu, G.J. Riggins, J.K. Willson, S.D. Markowitz, K.W. Kinzler, and B. Vogelstein Mutations of mitotic checkpoint genes in human cancers Nature 392 1998 300 303
32. R.G. Jaffrey, S.C. Pritchard, C. Clark, G.I. Murray, J. Cassidy, K.M. Kerr, M.C. Nicolson, and H.L. McLeod Genomic instability at the BUB1 locus in colorectal cancer, but not in non-small cell lung cancer Cancer Res 60 2000 4349 4352
33. B. Burwinkel, and M.W. Kilimann Unequal homologous recombination between LINE-1 elements as a mutational mechanism in human genetic disease J Mol Biol 277 1998 513 517