Synthesis of new 4-oxo-2-thioxo-1,2,3,4-tetrahydropyrimidine derivatives with an incorporated thiazolidinone moiety and testing their possible serine protease and cercarial elastase inhibitory effects with a possible prospective to block penetration of Schistosoma mansoni cercariae into the mice skin

Archives of Pharmacal Research

Volumn 28, Issue 9, 2005, Pages 1002-1012

  Bahgat, Mahmoud Mohamed ^a,b   Maghraby, Amany Sayed ^a   Heiba, Mogeda Emam ^a   Ruppel, Andreas ^c   Fathalla, Omar Abd Elfattah Mohamed ^a  

^a NATIONAL RESEARCH CENTRE   (Egypt)

^b Pharmaceutical and Drug Industries Research Division   (Egypt)

^c UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

Cercariae; Elastase; IgG; IgM; N' (4 Methylbenzylidene) 4 oxo 2 thioxo 1,2,3,4 tetrahydro pyrimidine 5 sulfonylhydrazide; Schistosoma mansoni

Indexed keywords

EID: 26444468916     PISSN: 02536269     EISSN: 02536269     Source Type: Journal    
DOI: 10.1007/BF02977392     Document Type: Article

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