Conjugation of lentivirus to paramagnetic particles via nonviral proteins allows efficient concentration and infection of primary acute myeloid leukemia cells

Journal of Virology

Volumn 79, Issue 20, 2005, Pages 13190-13194

  Chan, Lucas ^a   Nesbeth, Darren ^a   MacKey, Taylor ^a   Galea Lauri, Joanna ^a,c   Gäken, Joop ^a   Martin, Francisco ^b,d   Collins, Mary ^b   Mufti, Ghulam ^a   Farzaneh, Farzin ^a   Darling, David ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

^c GREAT ORMOND STREET HOSPITAL   (United Kingdom)

^d IPB Lopez Neyra   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

CELL SURFACE PROTEIN; MEMBRANE PROTEIN; RETROVIRUS VECTOR; STREPTAVIDIN; VIRUS PROTEIN;

ACUTE GRANULOCYTIC LEUKEMIA; ARTICLE; BIOTINYLATION; BLAST CELL; CONCENTRATION (PARAMETERS); CONJUGATION; CONTROLLED STUDY; GENETIC TRANSDUCTION; HALF LIFE TIME; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; LENTIVIRINAE; LEUKEMIA CELL; MAGNET; MURINE LEUKEMIA VIRUS; NONHUMAN; PRIORITY JOURNAL; PURIFICATION; TECHNIQUE; VESICULAR STOMATITIS VIRUS; VIRUS ENVELOPE; VIRUS INFECTION; VIRUS INFECTIVITY;

CELL LINE; GENE TRANSFER TECHNIQUES; GENETIC VECTORS; GTP-BINDING PROTEINS; HUMANS; LENTIVIRUS; LEUKEMIA, MYELOCYTIC, ACUTE; MAGNETICS; MEMBRANE PROTEINS; MICROSPHERES; TUMOR CELLS, CULTURED; VESICULAR STOMATITIS-INDIANA VIRUS; VIRUS REPLICATION;

AMPHOTROPIC MURINE LEUKEMIA VIRUS; LENTIVIRUS; VESICULAR STOMATITIS VIRUS;

EID: 26444468914     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.79.20.13190-13194.2005     Document Type: Article

References (46)

1. Arthur, L. O., J. W. Bess, R. C. Sowder, R. E. Benveniste, D. L. Mann, J. C. Chermann, and L. E. Henderson. 1992. Cellular proteins bound to immunodeficiency viruses: implications for pathogenesis and vaccines. Science 258:1935-1938.
2. Beer, C., A. Meyer, K. Muller, and M. Wirth. 2003. The temperature stability of mouse retroviruses depends on the cholesterol levels of viral lipid shell and cellular plasma membrane. Virology 308:137-146.
3. Beyer, W. R., M. Westphal, W. Ostertag, and D. von Laer. 2002. Oncoretrovirus and lentivirus vectors pseudotyped with lymphocytic choriomeningitis virus glycoprotein: generation, concentration, and broad host range. J. Virol. 76:1488-1495.
4. Bordígnon, C., C. Bonini, S. Verzelettí, N. Nobili, D. Maggíoni, C. Traversarí, R. Giavazzi, P. Servida, E. Zappone, E. Benazzi, M. Bernadi, F. Porta, G. Ferrari, F. Mavilio, S. Rossini, R. M. Blaese, and F. Candotti. 1995. Clinical protocol: transfer of the HSV-tk gene into donor peripheral blood lymphocytes for in vivo modulation of donor anti-tumor immunity after allogeneic bone marrow transplant. Hum. Gene Ther. 6:813-819.
5. Burns, J. C., T. Friedmann, W. Driever, M. Burrascano, and J. K. Yee. 1993. Vesicular stomatitis-virus G glycoprotein pseudotyped retroviral vectors-concentration to very high-titre and efficient gene-transfer into mammalian and non-mammalian cells. Proc. Natl. Acad. Sci. USA 90:8033-8037.
6. Chan, L., N. Hardwick, D. Darling, J. Galea-Lauri, J. Gäken, S. Devereux, M. Kemeny, G. Mufti, and F. Farzaneh. 2005. IL-2/B7.1 fusagene transduction of AML blasts by a self-inactivating lentiviral vector stimulates T cell responses in vitro: a strategy to generate whole cell vaccines for AML. Mol. Ther. 11:120-131.
7. + hematopoietic cells using novel ligand display technology. Blood 104:2697-2703.
8. Chandrashekran, A., M. Y. Gordon, D. Darling, F. Farzaneh, and C. Casimir. 2004. Growth factor displayed on the surface of retroviral particles without manipulation of envelope proteins is biologically active and can enhance transduction. J. Gene Med. 6:1189-1196.
9. Charbonnier, A., B. Gaugler, D. Sainty, M. Lafage-Pochitaloff, and D. Olive. 1999. Human acute myeloblastic leukemia cells differentiate in vitro into mature dendritic cells and induce differentiation of cytotoxic T cells against autologous leukemias. Eur. J. Immunol. 29:2567-2578.
10. Chen, J., L. Reeves, N. Sanburn, J. Croop, D. A. Williams, and K. Cornetta. 2001. Packaging cell line DNA contamination of vector supernatants: implication for laboratory and clinical research. Virology 282:186-197.
11. Coil, D. A., J. H. Strickler, S. K. Rai, and A. D. Miller. 2001. Jaagsiekte sheep retrovirus Env protein stabilizes retrovirus vectors against inactivation by lung surfactant, centrifugation, and freeze-thaw cycling. J. Virol. 75:8864-8867.
12. Coleman, J. E., M. J. Huentelman, S. Kasparov, B. L. Metcalfe, J. F. R. Paton, M. J. Katovich, S. L. Semple-Rowland, and M. K. Raizada. 2003. Efficient large-scale production and concentration of HIV-1 based lentiviral vectors for use in vivo. Physiol. Genomics 12:221-228.
13. Cosset, F.-L., Y. Takeuchi, J.-L. Battini, R. A. Weiss, and M. K. L. Collins. 1995. High-titer packaging cells producing recombinant retroviruses resistant to human serum. J. Virol. 69:7430-7436.
14. Demaison, C., K. Parsley, G. Brouns, M. Scherr, K. Battmer, C. Kinnon, M. Grez, and A. J. Thrasher. 2002. High-level transduction and gene expression in hematopoietic repopulating cells using a human immunodeficiency virus type 1-based lentiviral vector containing an internal spleen focus forming virus promoter. Hum. Gene Ther. 13:803-813.
15. Dohring, C., L. Angman, G. Spagnoli, and A. Lanzavecchia. 1994. T-helper-cell-independent and accessory-cell-independent cytotoxic responses to human tumor-cells transfected with a B7 retroviral vector. Int. J. Cancer 57:754-759.
16. Esser, M. T., D. R. Graham, L. V. Coren, C. M. Trubey, J. W. Bess, L. O. Arthur, D. E. Ott, and J. D. Lifson. 2001. Differential incorporation of CD45, CD80 (B7-1), CD86 (B7-2), and major histocompatibility complex class I and II molecules in human immunodeficiency virus type 1 virions and microvesicles: implications for viral pathogenesis and immune regulation. J. Virol. 75:6173-6182.
17. Fortin, J.-F., R. Cantin, G. Lamontagne, and M. Tremblay. 1997. Host-derived ICAM-1 glycoproteins incorporated on human immunodeficiency virus type 1 are biologically active and enhance viral infectivity. J. Virol. 71:3588-3596.
18. Gäken, J., J. Jiang, K. Daniel, E. van Berkel, C. Hughes, M. Kuiper, D. Darling, M. Tavassoli, J. Galea-Lauri, K. Ford, M. Kemeny, S. Russell, and F. Farzaneh. 2000. Fusagene vectors: a novel strategy for the expression of multiple genes from a single cistron. Gene Ther. 7:1979-1985.
19. Galea-Lauri, J. 2002. Immunological weapons against acute myeloid leukaemia. Immunology 107:20-27.
20. Galea-Lauri, J., D. Darling, S.-U. Gan, L. Krivochtchapov, J. Gäken, B. Souberbeille, and F. Farzaneh. 1999. Expression of a variant CD28 on a sub-population of human NK cells: implications for B7-mediated stimulation of NK cells. J. Immunol. 163:62-70.
21. + cells transduced by concentrated oncoretroviral vector particles pseudotyped with the feline endogenous retrovirus (RD114) envelope protein. J. Virol. 75:9995-9999.
22. Giguere, J.-F., S. Bounou, J.-S. Paquette, J. Madrenas, and M. J. Tremblay. 2004. Insertion of host-derived costimulatory molecules CD80 (B7.1) and CD86 (B7.2) into human immunodeficiency virus type 1 affects the virus life cycle. J. Virol. 78:6222-6232.
23. Haim, H., I. Steiner, and A. Panet. 2005. Synchronized infection of cell cultures by magnetically controlled virus. J. Virol. 79:622-625.
24. Hanawa, H., P. F. Kelly, A. C. Nathwani, D. A. Persons, J. A. Vandegriff, P. Hargrove, E. F. Vanin, and A. W. Neinhuis. 2002. Comparison of various envelope proteins for their ability to pseudotype lentiviral vectors and transduce primitive hematopoietic cells from human blood. Mol. Ther. 5:242-251.
25. Harrison, B. D., J. A. Adams, M. Briggs, M. L. Brereton, and J. A. Yin. 2001. Stimulation of autologous proliferative and cytotoxic T-cell responses by "leukaemic dendritic cells" derived from blast cells in acute myeloid leukaemia. Blood 97:2764-2771.
26. Hirst, W. J. R., A. Buggins, D. Darling, J. Gäken, F. Farzaneh, and G. J. Mufti. 1997. Enhanced immune costimulatory activity of primary acute myeloid leukaemia blasts after gene transfer of B7.1. Gene Ther. 4:691-699.
27. Ho, A. Y. L., A. Paglucia, M. Kenyon, J. E. Parker, A. Mijovic, S. Devereux, and G. J. Mufti. 2004. Reduced-intensity allogcneic hematopoietic stem cell transplantation for myelodysplastic syndrome and acute myeloid leukaemia with multilineage dysplasia using fludarabine, busulphan, and alemtuzmab (FBC) conditioning. Blood 104:1616-1623.
28. Hughes, C., J. Galea-Lauri, F. Farzaneh, and D. Darling. 2001. Streptavidin paramagnetic particles provide a choice of three affinity-based capture and magnetic concentration strategies for retroviral vectors. Mol. Ther. 3:623-630.
29. Koya, R. C., N. Kasahara, V. Pullarkat, A. M. Levine, and R. Stripecke. 2002. Transduction of acute myeloid leukemia cells with third generation self-inactivating lentiviral vectors expressing CD80 and GM-CSF: effects on proliferation, differentiation, and stimulation of allogeneic and autologous anti-leukemia immune responses. Leukemia 16:1645-1654.
30. Mah, C., T. J. Fraites, I. Zolotukhin, S. H. Song, T. R. Flotte, J. Dobson, C. Batich, and B. J. Byrne. 2002. Improved method of recombinant AAV2 delivery for systemic targeted gene therapy. Mol. Ther. 6:106-112.
31. Naldini, L., U. Blomer, P. Gallay, D. Ory, R. Mulligan, F. H. Gage, I. M. Verma, and D. Trono. 1996. In vivo gene delivery and stable transduction of non dividing cells by a lentiviral vector. Science 272:263-267.
32. Nyambi, P. N., M. K. Gorny, L. Bastiani, G. van der Groen, C. Williams, and S. Zoller-Pazner. 1998. Mapping epitopes exposed on intact human immunodeficiency virus type 1 (HIV-1) virions: a new strategy for studying the immunologic relatedness of HIV-1. J. Virol. 72:9384-9391.
33. Olsen, J. C. 1998. Gene transfer vectors derived from equine infectious anaemia virus. Gene Ther. 5:1481-1487.
34. Pandori, M. W., D. A. Hobson, and T. Sano. 2002. Adenovirus-microbead conjugates possess enhanced infectivity: a new strategy for localized gene therapy. Virology 299:204-212.
35. Pham, L., H. Ye, F.-L. Cosset, S. J. Russell, and K. W. Peng. 2001. Concentration of viral vectors by co-precipitation with calcium phosphate. J. Gene Med. 3:188-194.
36. Pickl, W. F., F. X. Pimentel-Muinos, and B. Seed. 2001. Lipid rafts and pscudotyping. J. Virol. 75:7175-7183.
37. Raty, J. K., K. J. Airenne, A. T. Marttilla, V. Marjomaki, V. P. Haytonen, P. Lehtolainen, O. H. Laitinen, A. J. Mahonen, M. S. Kulomaa, and S. Yla-Hertuala. 2002. Enhanced gene delivery by avidin-displaying baculovirus. Mol. Ther. 9:282-291.
38. Reiser, J. 2000. Production and concentration of pseudotyped HIV-1-based gene transfer vectors. Gene Ther. 7:910-913.
39. Scherer, F., M. Anton, U. Schillinger, J. Henkel, C. Bergemann, A. Kruger, B. Gansbacher, and C. Plank. 2002. Magnetofection: enhancing and targeting gene delivery by magnetic force in vitro and in vivo. Gene Ther. 9:102-109.
40. Stitz, J., C. J. Buchholz, M. Engelstadter, W. Uckert, U. Bloemer, I. Schmitt, and K. Cichutek. 2000. Lentiviral vectors pseudotyped with envelope glycoproteins derived from gibbon apc leukemia virus and murine leukemia virus 10A1. Virology 273:16-20.
41. Strang, B. L., Y. Ikeda, F.-L. Cosset, M. K. L. Collins, and Y. Takeuchi. 2004. Characterisation of HIV-1 vectors with gammaretrovirus envelope glycoproteins produced from stable packaging cells. Gene Ther. 11:591-598.
42. Stripecke, R., A. A. Cardoso, K. A. Pepper, D. G. Skelton, X. J. Yu, L. Mascarenhas, K. I. Weinberg, L. M. Nadler, and D. B. Kohn. 2000. Lentiviral vectors for efficient delivery of CD80 and granulocyte-macrophage-colony- stimulating factor in human acute lymphoblastic leukemia cells and acute myeloid leukemia cells to induce antileukemic responses. Blood 96:1317-1326.
43. Tai, M.-F., K.-M. Chi, K.-H. W. Lau, D. J. Baylink, and S. T. Chen. 2003. Generation of magnetic retroviral vectors with magnetic nanoparticles. Rev. Adv. Mater. Sci. 5:319-323.
44. Zhang, B., H. Q. Xia, G. Cleghorn, G. Gobe, M. West, and M. Q. Wei. 2001. A highly efficient and consistent method for harvesting large volumes of high-titre lentiviral vectors. Gene Ther. 8:1745-1751.
45. Zufferey, R., T. Dull, R. J. Mandel, A. Bukovsky, D. Quiroz, L. Naldini, and D. Trono. 1998. Self-inactivating lentivirus vector for safe and efficient in vivo gene delivery. J. Virol. 72:9873-9880.
46. Zufferey, R., D. Nagy, R. J. Mandel, L. Naldini, and D. Trono. 1997. Multiply attenuated lentiviral vector achieves efficient gene delivery in vivo. Nat. Biotechnol. 15:871-875.