Dmoesin controls actin-based cell shape and polarity during Drosophila melanogaster oogenesis

Nature Cell Biology

Volumn 4, Issue 10, 2002, Pages 782-789

  Polosello, Cédric ^a   Delon, Isabelle ^a   Valenti, Philippe ^a   Ferrer, Pierre ^a   Payre, François ^a  

^a Centre de Biologie du Developpement Toulouse   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN; DMOESIN; EZRIN; MEMBRANE PROTEIN; MOESIN; RADIXIN; UNCLASSIFIED DRUG;

ACTIN FILAMENT; ANIMAL CELL; ARTICLE; CELL MEMBRANE; CELL POLARITY; CELL SHAPE; CONTROLLED STUDY; DROSOPHILA MELANOGASTER; GENE MUTATION; GENETIC ANALYSIS; MICROFILAMENT; NONHUMAN; OOCYTE CORTEX; OOCYTE DEVELOPMENT; PRIORITY JOURNAL; PROTEIN LOCALIZATION;

ANIMALS; BLOOD PROTEINS; CELL POLARITY; CELL SIZE; CYTOSKELETAL PROTEINS; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; FEMALE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; MALE; MEMBRANE PROTEINS; MICROFILAMENTS; MOLECULAR SEQUENCE DATA; MUTATION; OOCYTES; OOGENESIS; PHOSPHOPROTEINS; PHYLOGENY; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT FUSION PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID; THREONINE;

ANIMALIA; DROSOPHILA MELANOGASTER; HEXAPODA; MELANOGASTER;

EID: 0036797220     PISSN: 14657392     EISSN: None     Source Type: Journal    
DOI: 10.1038/ncb856     Document Type: Article

References (45)

1. Lee, E., Pang, K. & Knecht, D. The regulation of actin polymerization and cross-linking in Dictyostelium. Biochim. Biophys. Acta 1525, 217-227 (2001).
2. Tsukita, S. & Yonemura, S. Cortical actin organization: lessons from ERM (Ezrin/Radixin/Moesin) proteins. J. Biol. Chem. 274, 34507-34510 (1999).
3. Mangeat, P., Roy, C. & Martin, M. ERM proteins in cell adhesion and membrane dynamics. Trends Cell Biol. 9, 187-192 (1999).
4. Bretscher, A., Chambers, D., Nguyen, R. & Reczek, D. Erm-merlin and ebp50 protein families in plasma membrane organization and function. Annu. Rev. Cell Dev. Biol. 16, 113-143 (2000).
5. Turunen, O., Wahlstrom, T. & Vaheri, A. Ezrin has a COOH-terminal actin-binding site that is conserved in the Ezrin protein family. J. Cell Biol. 126, 1445-1453 (1994).
6. Tsukita, S., Oishi, K., Sato, N., Sagara, J. & Kawai, A. ERM family members as molecular linkers between the cell surface glycoprotein CD44 and actin-based cytoskeletons. J. Cell Biol. 126, 391-401 (1994).
7. + translocation. Mol. Cell 6, 1425-1436 (2000).
8. Chishti, A. H. et al. The FERM domain: a unique module involved in the linkage of cytoplasmic proteins to the membrane. Trends Biochem. Sci. 23, 281-282 (1998).
9. Pearson, M. A., Reczek, D., Bretscher, A. & Karplus, P. A. Structure of the ERM protein Moesin reveals the FERM domain fold masked by an extended actin binding tail domain. Cell 101, 259-270 (2000).
10. Ishikawa, H. et al. Structural conversion between open and closed forms of Radixin: low- angle shadowing electron microscopy. J. Mol. Biol. 310, 973-978 (2001).
11. Nakamura, F., Amieva, M. R. & Furthmayr, H. Phosphorylation of threonine 558 in the carboxyl-terminal actin-binding domain of Moesin by thrombin activation of human platelets. J. Biol. Chem. 270, 31377-31385 (1995).
12. Takeuchi, K. et al. Perturbation of cell adhesion and microvilli formation by antisense oligonucleotides to ERM family members. J. Cell Biol. 125, 1371-1384 (1994).
13. Lamb, R. F. et al. Essential functions of Ezrin in maintenance of cell shape and lamellipodial extension in normal and transformed fibroblasts. Curr. Biol. 7, 682-688 (1997).
14. Doi, Y. et al. Normal development of mice and unimpaired cell adhesion/cell motility/actin-based cytoskeleton without compensatory up-regulation of Ezrin or Radixin in Moesin gene knockout. J. Biol. Chem. 274, 2315-2321 (1999).
15. McCartney, B. M. & Fehon, R. G. Distinct cellular and subcellular patterns of expression imply distinct functions for the Drosophila homologues of Moesin and the neurofibromatosis 2 tumour suppressor, merlin. J. Cell Biol. 133, 843-852 (1996).
16. Bourbon, H. M. et al. A P-insertion screen identifying novel X-linked essential genes in Drosophila. Mech. Dev. 110, 71-83 (2002).
17. van Eeden, F. & St Johnston, D. The polarisation of the anterior-posterior and dorsal-ventral axes during Drosophila oogenesis. Curr. Opin. Genet. Dev. 9, 396-404 (1999).
18. Baker, N. E. Localization of transcripts from the wingless gene in whole Drosophila embryos. Development 103, 289-298 (1988).
19. Hay, B., Jan, L. Y. & Jan, Y. N. Localization of Vasa, a component of Drosophila polar granules, in maternal-effect mutants that alter embryonic anteroposterior polarity. Development 109, 425-433 (1990).
20. Gavis, E. R. & Lehmann, R. Localization of nanos RNA controls embryonic polarity. Cell 71, 301-313 (1992).
21. Driever, W. & Nusslein-Volhard, C. The bicoid protein determines position in the Drosophila embryo in a concentration-dependent manner. Cell 54, 95-104 (1988).
22. Ephrussi, A., Dickinson, L. K. & Lehmann, R. Oskar organizes the germ plasm and directs localization of the posterior determinant nanos. Cell 66, 37-50 (1991).
23. Ephrussi, A. & Lehmann, R. Induction of germ cell formation by oskar. Nature 358, 387-392 (1992).
24. Kim-Ha, J., Smith, J. L. & Macdonald, P. M. oskar mRNA is localized to the posterior pole of the Drosophila oocyte. Cell 66, 23-35 (1991).
25. Theurkauf, W. E., Smiley, S., Wong, M. L. & Alberts, B. M. Reorganization of the cytoskeleton during Drosophila oogenesis: implications for axis specification and intercellular transport. Development 115, 923-936 (1992).
26. Theurkauf, W. E. Premature microtubule-dependent cytoplasmic streaming in cappuccino and spire mutant oocytes. Science 265, 2093-2096 (1994).
27. Manseau, L., Calley, J. & Phan, H. Profilin is required for posterior patterning of the Drosophila oocyte. Development 122, 2109-2116 (1996).
28. Clark, I. E., Jan, L. Y. & Jan, Y. N. Reciprocal localization of Nod and kinesin fusion proteins indicates microtubule polarity in the Drosophila oocyte, epithelium, neuron and muscle. Development 124, 461-470 (1997).
29. Clark, I., Giniger, E., Ruohola-Baker, H., Jan, L. Y. & Jan, Y. N. Transient posterior localization of a kinesin fusion protein reflects anteroposterior polarity of the Drosophila oocyte. Curr. Biol 4, 289-300 (1994).
30. Brendza, R. P., Serbus, L. R., Duffy, J. B. & Saxton, W. M. A function for kinesin I in the posterior transport of oskar mRNA and Staufen protein. Science 289, 2120-2122 (2000).
31. Robinson, D. N. & Cooley, L. Genetic analysis of the actin cytoskeleton in the Drosophila ovary. Annu. Rev. Cell Dev. Biol. 13, 147-170 (1997).
32. MacDougall, N. et al. Merlin, the Drosophila homologue of neurofibromatosis-2, is specifically required in posterior follicle cells for axis formation in the oocyte. Development 128, 665-673 (2001).
33. Oshiro, N., Fukata, Y. & Kaibuchi, K. Phosphorylation of Moesin by rho-associated kinase (Rho-kinase) plays a crucial role in the formation of microvilli-like structures. J. Biol. Chem. 273, 34663-34666 (1998).
34. Lantz, V. A., Clemens, S. E. & Miller, K. G. The actin cytoskeleton is required for maintenance of posterior pole plasm components in the Drosophila embryo. Mech. Dev. 85, 111-122 (1999).
35. Erdelyi, M., Michon, A. M., Guichet, A., Glotzer, J. B. & Ephrussi, A. Requirement for Drosophila cytoplasmic tropomyosin in oskar mRNA localization. Nature 377, 524-527 (1995).
36. Baum, B., Li, W. & Perrimon, N. A cyclase-associated protein regulates actin and cell polarity during Drosophila oogenesis and in yeast. Curr. Biol. 10, 964-973 (2000).
37. Verheyen, E. M. & Cooley, L. Profilin mutations disrupt multiple actin-dependent processes during Drosophila development. Development 120, 717-728 (1994).
38. Matsui, T. et al. Rho-kinase phosphorylates COOH-terminal threonines of Ezrin/Radixin/Moesin (ERM) proteins and regulates their head-to-tail association. J. Cell Biol. 140, 647-657 (1998).
39. Simons, P. C., Pietromonaco, S. F., Reczek, D., Bretscher, A. & Elias, L. C-terminal threonine phosphorylation activates ERM proteins to link the cell's cortical lipid bilayer to the cytoskeleton. Biochem. Biophys. Res. Commun. 253, 561-565 (1998).
40. Huang, L., Wong, T. Y., Lin, R. C. & Furthmayr, H. Replacement of threonine 558, a critical site of phosphorylation of Moesin in vivo, with aspartate activates F-actin binding of Moesin. Regulation by conformational change. J. Biol. Chem. 274, 12803-12810 (1999).
41. Hamada, K., Shimizu, T., Matsui, T., Tsukita, S. & Hakoshima, T. Structural basis of the membrane-targeting and unmasking mechanisms of the Radixin FERM domain. EMBO J. 19, 4449-4462 (2000).
42. 2-terminal domain of Ezrin correlates with its altered cellular distribution. J. Cell Biol. 151, 1067-1080 (2000).
43. Gautreau, A., Louvard, D. & Arpin, M. Morphogenic effects of Ezrin require a phosphorylation-induced transition from oligomers to monomers at the plasma membrane. J. Cell Biol. 150, 193-203 (2000).
44. Edwards, K. A., Demsky, M., Montague, R. A., Weymouth, N. & Kiehart, D. P. GFP-Moesin illuminates actin cytoskeleton dynamics in living tissue and demonstrates cell shape changes during morphogenesis in Drosophila. Dev. Biol. 191, 103-117 (1997).
45. Payre, F., Vincent, A. & Carreno, S. ovo/svb integrates Wingless and DER pathways to control epidermis differentiation. Nature 400, 271-275 (1999).