Roles of the two Drosophila CRYPTOCHROME structural domains in circadian photoreception

Science

Volumn 304, Issue 5676, 2004, Pages 1503-1506

  Busza, Ania ^a   Emery Le, Myai ^a   Rosbash, Michael ^b   Emery, Patrick ^a  

^a UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

^b BRANDEIS UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIODIVERSITY; CELL CULTURE; DEGRADATION; PHOTODETECTORS; PROTEINS;

CRYPTOCHROME (CRY); LIGHT EXPOSURES; PROTEASOMAL DEGRADATION; TIMELESS (TIM);

CYTOLOGY;

CRYPTOCHROME; DEOXYRIBODIPYRIMIDINE PHOTOLYASE; DNA; PROTEASOME;

BIOCHEMICAL PHENOMENA; CIRCADIAN RHYTHM;

ARABIDOPSIS; ARTICLE; CIRCADIAN RHYTHM; DEGRADATION; DNA REPAIR; DROSOPHILA; ENZYME ACTIVITY; FLY; GENE OVEREXPRESSION; INSECT; KINETICS; LIGHT; MUTANT; NONHUMAN; PHOTORECEPTOR; PHOTOSENSITIVITY; PHOTOTRANSDUCTION; PLANT; PRIORITY JOURNAL;

ANIMALS; ANIMALS, GENETICALLY MODIFIED; CELL LINE; CIRCADIAN RHYTHM; CYSTEINE ENDOPEPTIDASES; DARKNESS; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; EYE PROTEINS; FEMALE; LIGHT; MALE; MULTIENZYME COMPLEXES; MUTATION; NUCLEAR PROTEINS; PHOTORECEPTORS, INVERTEBRATE; PHOTOTRANSDUCTION; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, G-PROTEIN-COUPLED;

ARABIDOPSIS; INSECTA;

EID: 2642584009     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.1096973     Document Type: Article

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32. We thank A. Murad for help with real-time PCR; V. Suri for the pAc-per vector, R. Allada for the pAc-timha vector; E. Rosato, S. Waddell, and S. M. Reppert for critical reading of our manuscript; and J. Levine, R. Stanewsky, and members of our labs for helpful discussions and suggestions. Supported by a Young Investigator Award from the Richard and Susan Smith Family Foundation and NIH grant GM66777-01 (P.E.), NIH Cellular and Molecular Neurobiology training grant 5 T32 NS07366-08 (A.B.), and NIH grants P01 GM33205 and P01 NS44232 (M.R.).