Horseradish peroxidase mutants that autocatalytically modify their prosthetic heme group. Insights into mammalian peroxidase heme-protein covalent bonds

Journal of Biological Chemistry

Volumn 279, Issue 23, 2004, Pages 24131-24140

  Colas, Christophe ^a   Ortiz De Montellano, Paul R ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CATALYSIS; CHEMICAL BONDS; ENZYMES; ESTERS; MUTAGENESIS; PLANTS (BOTANY);

COVALENT BONDS; MUTANTS; MUTATIONS;

BIOCHEMISTRY;

3 HYDROXYMETHYLHEME; ASPARTIC ACID; CARBOXYLIC ACID; GLUTAMIC ACID; GLYCINE; HEME DERIVATIVE; HEMOPROTEIN; HORSERADISH PEROXIDASE; HYDROGEN PEROXIDE; LACTOPEROXIDASE; LEUCINE; METHYL GROUP; MUTANT PROTEIN; MYELOPEROXIDASE; PHENYLALANINE; SERINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CATALYSIS; CONTROLLED STUDY; COVALENT BOND; ENZYME MODIFICATION; ENZYME STABILITY; ENZYME STRUCTURE; MUTATION; NONHUMAN; OXIDATION; PRIORITY JOURNAL; SEQUENCE HOMOLOGY;

ANIMALS; CARBOXYLIC ACIDS; CATALYSIS; CELL LINE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CLONING, MOLECULAR; DNA; ELECTROPHORESIS, POLYACRYLAMIDE GEL; GLUTAMIC ACID; GLYCINE; HEME; HORSERADISH PEROXIDASE; HYDROGEN PEROXIDE; HYDROGEN-ION CONCENTRATION; INSECTS; KINETICS; LEUCINE; MASS SPECTROMETRY; MODELS, CHEMICAL; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; MUTATION; PEROXIDASE; PHENYLALANINE; PORPHYRINS; PROTEIN STRUCTURE, SECONDARY; SERINE; SPECTROPHOTOMETRY; TIME FACTORS; ULTRAVIOLET RAYS; VARIATION (GENETICS);

ANIMALIA; ARMORACIA RUSTICANA; MAMMALIA;

EID: 2642575909     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M401687200     Document Type: Article

References (44)

1. Fiedler, T. J., Davey, C. A., and Fenna, R. E. (2000) J. Biol. Chem. 275, 11964-11971
2. Colas, C., Kuo, J. M., and Ortiz de Montellano, P. R. (2002) J. Biol. Chem. 277, 7191-7200
3. Hoch, U., and Ortiz de Montellano, P. R. (2001) J. Biol. Chem. 276, 11339-11346
4. Henne, K. R., Kunze, K. L., Zheng, Y. M., Christmas, P., Soberman, R. J., and Rettie, A. E. (2001) Biochemistry 40, 12925-12931
5. Lebrun, L. A., Xu, F., Kroetz, D. L., and Ortiz de Montellano, P. R. (2002) Biochemistry 41, 5931-5937
6. Zheng, Y. M., Baer, B. R., Kneller, M. B., Henne, K. R., Kunze, K. L., and Rettie, A. E. (2003) Biochemistry 42, 4601-4606
7. Cheesman, M. J., Baer, B. R., Zheng, Y.-M., Gillam, E. M. J., and Rettie, A. E. (2003) Arch. Biochem. Biophys. 416, 17-24
8. Lebrun, L. A., Hoch, U., and Ortiz de Montellano, P. R. (2002) J. Biol. Chem. 277, 12755-12761
9. Barker, P. D., and Ferguson, S. J. (1999) Structure 7, R281-R290
10. Cowley, A. B., Lukat-Rodgers, G. S., Rodgers, K. R., and Benson, D. R. (2004) Biochemistry, 43, 1656-1666
11. Colas, C., and Ortiz de Montellano, P. R. (2003) Chem. Rev. 103, 2305-2332
12. DePillis, G. D., Ozaki, S., Kuo, J. M., Maltby, D. A., and Ortiz de Montellano, P. R. (1997) J. Biol. Chem. 272, 8857-8860
13. Kooter, I. M., Pierik, A. J., Merkx, M., Averill, B. A., Moguilevsky, N., Bollen, A., and Wever, R. (1997) J. Am. Chem. Soc. 119, 11452-11453
14. Picot, D., Loll, P. J., and Garavito, R. M. (1994) Nature 367, 243-249
15. Dunford, H. B. (1999) Heme Peroxidases, pp. 58-91, Wiley-VCH, New York
16. Newmyer, S. L., and Ortiz de Montellano, P. R. (1995) J. Biol. Chem. 270, 19430-19438
17. Savenkova, M. I., Kuo, J. M., and Ortiz de Montellano, P. R. (1998) Biochemistry 37, 10828-10836
18. Gajhede, M., Schuller, D. J., Henriksen, A., Smith, A. T., and Poulos, T. L. (1997) Nature 4, 1032-1038
19. Ator, M. A., and Ortiz de Montellano, P. R. (1987) J. Biol. Chem. 262, 1542-1551
20. O'Reilly, D. R., Miller, K. I., and Luckow, V. A. (1992) in Baculovirus Expression Vectors, pp. 124-138, W. H. Freeman and Co., New York
21. Nelson, D. P., and Kiesow, L. A. (1972) Anal. Biochem. 49, 474-478
22. Zeng, J., and Fenna, R. E. (1992) J. Mol. Biol. 203, 803-816
23. Henriksen, A., Mirza, O., Indiani, C., Teilum, K., Smulevich, G., Welinder, K., and Gajhede, M. (2001) Protein Sci. 10, 108-115
24. Morita, Y., Funatsu, J., and Mikami, B. (1993) in Plant Peroxidases: Biochemistry and Physiology (Welinder, K. G., Rasmussen, S. K., Pemnel, C., and Greppin, H., eds) pp. 35-42, University of Geneva, Geneva
25. Tanaka, M., Ishimori, K., and Morishima, I. (1998) Biochemistry 37, 2629-2638
26. Henriksen, A., Welinder, K. G., and Gajhede, M. (1998) J. Biol. Chem. 273, 2241-2248
27. Ortiz de Montellano, P. (1992) Annu. Rev. Pharmacol. Toxicol. 32, 89-107
28. Morawski, B., Lin, Z., Cirino, P., Joo, H., Bandara, G., and Arnold, F. H. (2000) Protein Eng. 13, 377-384
29. Meno, K., Jennings, S., Smith, A. T., Henriksen, A., and Gajhede, M. (2002) Acta Crystallogr. Sect. D Biol. Crystallogr. 58, 1803-1812
30. Smith, A. T., Sanders, S. A., Thorneley, R. N., Burke, J. F., and Bray, R. R. (1992) Eur. J. Biochem. 207, 507-519
31. Heering, H. A., Smith, A. T., and Smulevich, G. (2002) Biochem. J. 363, 571-579
32. Tanaka, M., Ishimori, K., Mukai, M., Kitagawa, T., and Morishima, I. (1997) Biochemistry 36, 9889-9898
33. Hasinoff, B. B., and Dunford, H. B. (1970) Biochemistry 9, 4930-4939
34. Patel, P. K., Mondal, M. S., Modi, S., and Behere, D. V. (1997) Biochim. Biophys. Acta 1339, 79-87
35. Jantschko, W., Furtmuller, P. G., Allegra, M., Livrea, M. A., Jakopitsch, C., Regelsberger, G., and Obinger, C. (2002) Arch. Biochem. Biophys. 398, 12-22
36. Tanaka, M., Ishirmori, K., and Morishima, I. (1996) Biochem. Biophys. Res. Commun. 227, 393-399
37. Howes, B., Heering, H. A., Roberts, T. O., Schneider-Belhadadd, F., Smith, A. T., and Smulevich, G. (2001) Biopolymers 62, 261-267
38. Nagano, S., Tanaka, M., Ishimori, K., Watanabe, Y., and Morishima, I. (1996) Biochemistry 35, 14251-14258
39. Savenkova, M. I., and Ortiz de Montellano, P. R. (1996) Arch. Biochem. Biophys. 351, 286-293
40. Gazaryan, I. G., Doseeva, V. V., Galkin, A. G., and Tishkov, V. I. (1994) FEBS Lett. 354, 248-250
41. Smith, A. T., Sanders, S. A., Greschik, H., Thorneley, R. N., Burke, J. F., and Bray, R. C. (1992) Biochem. Soc. Trans. 20, 340-345
42. Savenkova, M. I., Newmyer, S. L., and Ortiz de Montellano, P. R. (1996) J. Biol. Chem. 271, 24598-24603
43. Ozaki, S.-I., and Ortiz de Montellano, P. R. (1995) J. Am. Chem. Soc. 117, 7056-7064
44. Harris, R. Z., Liddell, P. A., Smith, K. M., and Ortiz de Montellano, P R. (1993) Biochemistry 32, 3658-3663