-
1
-
-
0012339446
-
Mechanism of action of IL2-Bax: An apoptosis-inducing chimeric protein targeted against interleukin-2 receptor expressing cells
-
Aqeilan R., Kedar R., Ben-Yehudah A., Lorberboum-Galski H. (2002) Mechanism of action of IL2-Bax: an apoptosis-inducing chimeric protein targeted against interleukin-2 receptor expressing cells. Biochem. J. 30, 332-338.
-
(2002)
Biochem. J.
, vol.30
, pp. 332-338
-
-
Aqeilan, R.1
Kedar, R.2
Ben-Yehudah, A.3
Lorberboum-Galski, H.4
-
2
-
-
0032779831
-
Interleukin 2-Bax: A novel prototype of human chimeric proteins for targeted therapy
-
Aqeilan R., Yarkoni S., Lorberboum-Galski H. (1999) Interleukin 2-Bax: a novel prototype of human chimeric proteins for targeted therapy. FEBS Lett. 457, 271-276.
-
(1999)
FEBS Lett.
, vol.457
, pp. 271-276
-
-
Aqeilan, R.1
Yarkoni, S.2
Lorberboum-Galski, H.3
-
3
-
-
0026743905
-
Pseudo-high affinity interleukin 2 (IL-2) receptor lacks the third component that is essential for functional IL-2 binding and signaling
-
Arima N., Kamio M., Imada K. et al. (1992) Pseudo-high affinity interleukin 2 (IL-2) receptor lacks the third component that is essential for functional IL-2 binding and signaling. J. Exp Med. 176, 1265-1272.
-
(1992)
J. Exp Med.
, vol.176
, pp. 1265-1272
-
-
Arima, N.1
Kamio, M.2
Imada, K.3
-
4
-
-
0035096593
-
Human recombinant interferon-alpha2a and interferon-alphaA/D have different effects on bleomycin-induced lung injury
-
Berkman N., Kremer S., Or R. et al. (2001) Human recombinant interferon-alpha2a and interferon-alphaA/D have different effects on bleomycin-induced lung injury. Respiration 68, 169-177.
-
(2001)
Respiration
, vol.68
, pp. 169-177
-
-
Berkman, N.1
Kremer, S.2
Or, R.3
-
6
-
-
0011801677
-
Chimeric cytotoxin IL2-PE40 delays and mitigates adjuvant-induced arthritis in rats
-
Case J.P., Lorberboum-Galski H., Lafyatis R., FitzGerald D., Wilder R.L., Pastan I. (1989) Chimeric cytotoxin IL2-PE40 delays and mitigates adjuvant-induced arthritis in rats. Proc. Natl Acad. Sci. USA 86, 287-291.
-
(1989)
Proc. Natl Acad. Sci. USA
, vol.86
, pp. 287-291
-
-
Case, J.P.1
Lorberboum-Galski, H.2
Lafyatis, R.3
FitzGerald, D.4
Wilder, R.L.5
Pastan, I.6
-
7
-
-
0020637814
-
Morphometric estimates of infiltrative cellular changes during the development of bleomycin-induced pulmonary fibrosis in hamsters
-
Chandler D.B., Hyde D.M., Giri S.N. (1983) Morphometric estimates of infiltrative cellular changes during the development of bleomycin-induced pulmonary fibrosis in hamsters. Am. J. Pathol 112, 170-177.
-
(1983)
Am. J. Pathol
, vol.112
, pp. 170-177
-
-
Chandler, D.B.1
Hyde, D.M.2
Giri, S.N.3
-
8
-
-
0021911534
-
Immunological involvement in pulmonary fibrosis induced by peplomycin
-
Ekimoto H., Aikawa M., Ohnuki T. et al. (1985) Immunological involvement in pulmonary fibrosis induced by peplomycin. J. Antibiot (Tokyo) 38, 94-98.
-
(1985)
J. Antibiot (Tokyo)
, vol.38
, pp. 94-98
-
-
Ekimoto, H.1
Aikawa, M.2
Ohnuki, T.3
-
9
-
-
0032982694
-
T cell independence of bleomycin-induced pulmonary fibrosis
-
Helene M., Lake-Bullock V., Zhu J., Hao H., Cohen D.A., Kaplan A.M. (1999) T cell independence of bleomycin-induced pulmonary fibrosis. J. Leukoc Biol. 65, 187-195.
-
(1999)
J. Leukoc Biol.
, vol.65
, pp. 187-195
-
-
Helene, M.1
Lake-Bullock, V.2
Zhu, J.3
Hao, H.4
Cohen, D.A.5
Kaplan, A.M.6
-
10
-
-
0026048242
-
Treatment of corneal allograft rejection with the cytotoxin IL-2-PE40
-
Herbert C.P., de Smet M.D., Roberge F.G. et al. (1991) Treatment of corneal allograft rejection with the cytotoxin IL-2-PE40. Transplantation 52, 470-474.
-
(1991)
Transplantation
, vol.52
, pp. 470-474
-
-
Herbert, C.P.1
De Smet, M.D.2
Roberge, F.G.3
-
11
-
-
0019451552
-
Bleomycin-induced pulmonary fibrosis: Correlation of biochemical, physiological, and histological changes
-
Hesterberg T.W., Gerriets J.E., Reiser K.M., Jackson A.C., Cross C.E., Last J.A. (1981) Bleomycin-induced pulmonary fibrosis: correlation of biochemical, physiological, and histological changes. Toxicol. Appl. Pharmacol. 60, 360-367.
-
(1981)
Toxicol. Appl. Pharmacol.
, vol.60
, pp. 360-367
-
-
Hesterberg, T.W.1
Gerriets, J.E.2
Reiser, K.M.3
Jackson, A.C.4
Cross, C.E.5
Last, J.A.6
-
12
-
-
0020663639
-
Alterations in collagen production in mixed mononuclear leukocyte-fibroblast cultures
-
Hibbs M.S., Postlethwaite A.E., Mainardi C.L., Seyer J.M., Kang A.H. (1983) Alterations in collagen production in mixed mononuclear leukocyte-fibroblast cultures. J. Exp Med. 157, 47-59.
-
(1983)
J. Exp Med.
, vol.157
, pp. 47-59
-
-
Hibbs, M.S.1
Postlethwaite, A.E.2
Mainardi, C.L.3
Seyer, J.M.4
Kang, A.H.5
-
14
-
-
0036408364
-
Time course of bleomycin-induced lung fibrosis
-
Izbicki G., Segel M.J., Christensen T.G., Conner M.W., Breuer R. (2002b) Time course of bleomycin-induced lung fibrosis. Int. J. Exp. Pathol. 83, 111-119.
-
(2002)
Int. J. Exp. Pathol.
, vol.83
, pp. 111-119
-
-
Izbicki, G.1
Segel, M.J.2
Christensen, T.G.3
Conner, M.W.4
Breuer, R.5
-
15
-
-
0017063344
-
Lymphokine stimulation of collagen accumulation
-
Johnson R.L., Ziff M. (1976) Lymphokine stimulation of collagen accumulation. J. Clin. Invest. 58, 240-252.
-
(1976)
J. Clin. Invest.
, vol.58
, pp. 240-252
-
-
Johnson, R.L.1
Ziff, M.2
-
16
-
-
0031965748
-
Idiopathic pulmonary fibrosis: Clinical relevance of pathologic classification
-
Katzenstein A.L. & Myers J.L. (1998) Idiopathic pulmonary fibrosis: clinical relevance of pathologic classification. Am. J. Respir. Crit. Care Med. 157, 1301-1315.
-
(1998)
Am. J. Respir. Crit. Care Med.
, vol.157
, pp. 1301-1315
-
-
Katzenstein, A.L.1
Myers, J.L.2
-
17
-
-
0025162698
-
IL-2-PE40 prevents the development of tumors in mice injected with IL-2 receptor expressing EL4 transfectant tumor cells
-
Kozak R.W., Lorberboum-Galski H., Jones L. et al. (1990) IL-2-PE40 prevents the development of tumors in mice injected with IL-2 receptor expressing EL4 transfectant tumor cells. J. Immunol. 145, 2766-2771.
-
(1990)
J. Immunol.
, vol.145
, pp. 2766-2771
-
-
Kozak, R.W.1
Lorberboum-Galski, H.2
Jones, L.3
-
18
-
-
0032823734
-
Effect of immunomodulators on bleomycin-induced lung injury
-
Kremer S., Breuer R., Lossos I.S. et al. (1999) Effect of immunomodulators on bleomycin-induced lung injury. Respiration 66, 455-462.
-
(1999)
Respiration
, vol.66
, pp. 455-462
-
-
Kremer, S.1
Breuer, R.2
Lossos, I.S.3
-
19
-
-
0032848335
-
The effect of enoxaparin on bleomycin-induced lung injury in mice
-
Laxer U., Lossos I.S., Gillis S. et al. (1999) The effect of enoxaparin on bleomycin-induced lung injury in mice. Exp. Lung Res. 25, 531-541.
-
(1999)
Exp. Lung Res.
, vol.25
, pp. 531-541
-
-
Laxer, U.1
Lossos, I.S.2
Gillis, S.3
-
20
-
-
0025047009
-
Bleomycin: A pharmacologic tool in the study of the pathogenesis of interstitial pulmonary fibrosis
-
Lazo J.S., Hoyt D.G., Sebti S.M., Pitt B.R. (1990) Bleomycin: a pharmacologic tool in the study of the pathogenesis of interstitial pulmonary fibrosis. Pharmacol. Ther. 47, 347-358.
-
(1990)
Pharmacol. Ther.
, vol.47
, pp. 347-358
-
-
Lazo, J.S.1
Hoyt, D.G.2
Sebti, S.M.3
Pitt, B.R.4
-
22
-
-
0024121599
-
Cytotoxic activity of an interleukin 2-pseudomonas exotoxin chimeric protein produced in Escherichia coli
-
Lorberboum-Galski H., FitzGerald D., Chaudhary V., Adhya S., Pastan I. (1988a) Cytotoxic activity of an interleukin 2-pseudomonas exotoxin chimeric protein produced in Escherichia coli. Proc. Natl. Acad. Sci. USA 85, 1922-1926.
-
(1988)
Proc. Natl. Acad. Sci. USA
, vol.85
, pp. 1922-1926
-
-
Lorberboum-Galski, H.1
FitzGerald, D.2
Chaudhary, V.3
Adhya, S.4
Pastan, I.5
-
23
-
-
0025194166
-
IL2-PE664Glu, a new chimeric protein cytotoxic to human-activated T lymphocytes
-
Lorberboum-Galski H., Garsia R.J., Gately M. et al. (1990) IL2-PE664Glu, a new chimeric protein cytotoxic to human-activated T lymphocytes. J. Biol. Chem. 265, 16311-16317.
-
(1990)
J. Biol. Chem.
, vol.265
, pp. 16311-16317
-
-
Lorberboum-Galski, H.1
Garsia, R.J.2
Gately, M.3
-
24
-
-
0024202754
-
Interleukin 2 (IL2) PE40 is cytotoxic to cells displaying either the p55 or p70 subunit of the IL2 receptor
-
Lorberboum-Galski H., Kozak R.W., Waldmann T.A., Bailon P., FitzGerald D.J., Pastan I. (1988b) Interleukin 2 (IL2) PE40 is cytotoxic to cells displaying either the p55 or p70 subunit of the IL2 receptor. J. Biol. Chem. 263, 18650-18656.
-
(1988)
J. Biol. Chem.
, vol.263
, pp. 18650-18656
-
-
Lorberboum-Galski, H.1
Kozak, R.W.2
Waldmann, T.A.3
Bailon, P.4
FitzGerald, D.J.5
Pastan, I.6
-
25
-
-
0025969219
-
Administration of IL-2-PE40 via osmotic pumps prevents adjuvant induced arthritis in rats. Improved therapeutic index of IL-2-PE40 administered by continuous infusion
-
Lorberboum-Galski H., Lafyatis R., Case J.P., FitzGerald D., Wilder R.L., Pastan I. (1991) Administration of IL-2-PE40 via osmotic pumps prevents adjuvant induced arthritis in rats. Improved therapeutic index of IL-2-PE40 administered by continuous infusion. Int. J. Immunopharmacol. 13, 305-315.
-
(1991)
Int. J. Immunopharmacol.
, vol.13
, pp. 305-315
-
-
Lorberboum-Galski, H.1
Lafyatis, R.2
Case, J.P.3
FitzGerald, D.4
Wilder, R.L.5
Pastan, I.6
-
26
-
-
0034721857
-
The effect of suramin on bleomycin-induced lung injury
-
Lossos I.S., Izbicki G., Or R., Goldstein R.H., Breuer R. (2000) The effect of suramin on bleomycin-induced lung injury. Life Sci. 67, 2873-2881.
-
(2000)
Life Sci.
, vol.67
, pp. 2873-2881
-
-
Lossos, I.S.1
Izbicki, G.2
Or, R.3
Goldstein, R.H.4
Breuer, R.5
-
27
-
-
0036056306
-
Cyclosporin a upmodulates bleomycin-induced pulmonary fibrosis in BALB/c mice
-
Lossos I.S., Or R., Ginzburg V., Christensen T.G., Mashriki Y., Breuer R. (2002) Cyclosporin A upmodulates bleomycin-induced pulmonary fibrosis in BALB/c mice. Respiration 69, 344-349.
-
(2002)
Respiration
, vol.69
, pp. 344-349
-
-
Lossos, I.S.1
Or, R.2
Ginzburg, V.3
Christensen, T.G.4
Mashriki, Y.5
Breuer, R.6
-
28
-
-
0024273437
-
IL-2-PE40 is cytotoxic for activated T lymphocytes expressing IL-2 receptors
-
Ogata M., Lorberboum-Galski H., FitzGerald D., Pastan I. (1988) IL-2-PE40 is cytotoxic for activated T lymphocytes expressing IL-2 receptors. J. Immunol. 141, 4224-4228.
-
(1988)
J. Immunol.
, vol.141
, pp. 4224-4228
-
-
Ogata, M.1
Lorberboum-Galski, H.2
FitzGerald, D.3
Pastan, I.4
-
29
-
-
0021324651
-
Lymphocyte modulation of fibroblast function in vitro: Stimulation and inhibition of collagen production by different effector molecules
-
Postlethwaite A.E., Smith G.N., Mainardi C.L., Seyer J.M., Kang A.H. (1984) Lymphocyte modulation of fibroblast function in vitro: stimulation and inhibition of collagen production by different effector molecules. J. Immunol. 132, 2470-2477.
-
(1984)
J. Immunol.
, vol.132
, pp. 2470-2477
-
-
Postlethwaite, A.E.1
Smith, G.N.2
Mainardi, C.L.3
Seyer, J.M.4
Kang, A.H.5
-
30
-
-
0024306276
-
Selective immunosuppression of activated T cells with the chimeric toxin IL-2-PE40. Inhibition of experimental autoimmune uveoretinitis
-
Roberge F.G., Lorberboum-Galski H., Le Hoang P. et al. (1989) Selective immunosuppression of activated T cells with the chimeric toxin IL-2-PE40. Inhibition of experimental autoimmune uveoretinitis. J. Immunol. 143, 3498-3502.
-
(1989)
J. Immunol.
, vol.143
, pp. 3498-3502
-
-
Roberge, F.G.1
Lorberboum-Galski, H.2
Le Hoang, P.3
-
31
-
-
0025797474
-
Chimeric cytotoxin IL2-PE40 inhibits relapsing experimental allergic encephalomyelitis
-
Rose J.W., Lorberboum-Galski H., Fitzgerald D. et al. (1991) Chimeric cytotoxin IL2-PE40 inhibits relapsing experimental allergic encephalomyelitis. J. Neuroimmunol. 32, 209-217.
-
(1991)
J. Neuroimmunol.
, vol.32
, pp. 209-217
-
-
Rose, J.W.1
Lorberboum-Galski, H.2
Fitzgerald, D.3
-
32
-
-
0020618189
-
The effects of the nude (nu/nu) mutation on bleomycin-induced pulmonary fibrosis. A biochemical evaluation
-
Schrier D.J., Phan S.H., McGarry B.M. (1983) The effects of the nude (nu/nu) mutation on bleomycin-induced pulmonary fibrosis. A biochemical evaluation. Am. Rev. Respir. Dis. 127, 614-617.
-
(1983)
Am. Rev. Respir. Dis.
, vol.127
, pp. 614-617
-
-
Schrier, D.J.1
Phan, S.H.2
McGarry, B.M.3
-
33
-
-
0034776350
-
All-trans-retinoic acid (ATRA) is of no benefit in bleomycin-induced lung injury
-
Segel M.J., Or R., Tzurel A. et al. (2001) All-trans-retinoic acid (ATRA) is of no benefit in bleomycin-induced lung injury. Pulm Pharmacol. Ther. 14, 403-407.
-
(2001)
Pulm Pharmacol. Ther.
, vol.14
, pp. 403-407
-
-
Segel, M.J.1
Or, R.2
Tzurel, A.3
-
34
-
-
0030017322
-
The effect of an anti-CD3 monoclonal antibody on bleomycin-induced lymphokine production and lung injury
-
Sharma S.K., MacLean J.A., Pinto C., Kradin R.L. (1996) The effect of an anti-CD3 monoclonal antibody on bleomycin-induced lymphokine production and lung injury. Am. J. Respir. Crit. Care Med. 154, 193-200.
-
(1996)
Am. J. Respir. Crit. Care Med.
, vol.154
, pp. 193-200
-
-
Sharma, S.K.1
MacLean, J.A.2
Pinto, C.3
Kradin, R.L.4
-
35
-
-
0018136194
-
Chronic interstitial pulmonary fibrosis produced in hamsters by endotracheal bleomycin. Lung volumes, volume-pressure relations, carbon monoxide uptake, and arterial blood gas studied
-
Snider G.L., Celli B.R., Goldstein R.H., O'Brien J.J., Lucey E.G. (1978) Chronic interstitial pulmonary fibrosis produced in hamsters by endotracheal bleomycin. Lung volumes, volume-pressure relations, carbon monoxide uptake, and arterial blood gas studied. Am. Rev. Respir. Dis. 117, 289-297.
-
(1978)
Am. Rev. Respir. Dis.
, vol.117
, pp. 289-297
-
-
Snider, G.L.1
Celli, B.R.2
Goldstein, R.H.3
O'Brien, J.J.4
Lucey, E.G.5
-
36
-
-
0030765937
-
Interleukin-2 (IL-2) receptor alpha, beta and gamma subunit expression as a function of B-cell lineage ontogeny: The use of IL-2-PE66 (4Glu) to characterize internalization via IL-2 receptor subunits
-
Steinberger I., Ben-Bassat H., Hochberg E., Lorberboum-Galski H. (1997) Interleukin-2 (IL-2) receptor alpha, beta and gamma subunit expression as a function of B-cell lineage ontogeny: the use of IL-2-PE66 (4Glu) to characterize internalization via IL-2 receptor subunits. Scand. J. Immunol. 46, 129-136.
-
(1997)
Scand. J. Immunol.
, vol.46
, pp. 129-136
-
-
Steinberger, I.1
Ben-Bassat, H.2
Hochberg, E.3
Lorberboum-Galski, H.4
-
37
-
-
0028793407
-
Interleukin-2 pseudomonas exotoxin chimeric protein is cytotoxic to B cell cultures derived from myasthenia gravis patients
-
Steinberger I., Brenner T., Lorberboum-Galski H. (1995) Interleukin-2 pseudomonas exotoxin chimeric protein is cytotoxic to B cell cultures derived from myasthenia gravis patients. J. Neurol. Sci. 133, 183-191.
-
(1995)
J. Neurol. Sci.
, vol.133
, pp. 183-191
-
-
Steinberger, I.1
Brenner, T.2
Lorberboum-Galski, H.3
-
38
-
-
0018629834
-
Bleomycin-induced interstitial pulmonary disease in the nude, athymic mouse
-
Szapiel S.V., Elson N.A., Fulmer J.D., Hunninghake G.W., Crystal R.G. (1979) Bleomycin-induced interstitial pulmonary disease in the nude, athymic mouse. Am. Rev. Respir. Dis. 120, 893-899.
-
(1979)
Am. Rev. Respir. Dis.
, vol.120
, pp. 893-899
-
-
Szapiel, S.V.1
Elson, N.A.2
Fulmer, J.D.3
Hunninghake, G.W.4
Crystal, R.G.5
-
39
-
-
0027394657
-
The IL-2/IL-2 receptor system: A current overview
-
Taniguchi T. & Minami Y. (1993) The IL-2/IL-2 receptor system: a current overview. Cell 73, 5-8.
-
(1993)
Cell
, vol.73
, pp. 5-8
-
-
Taniguchi, T.1
Minami, Y.2
-
40
-
-
0021361792
-
A comparison of lymphocyte populations in lung tissue and in bronchoalveolar lavage fluid of rats at various times during the development of bleomycin-induced pulmonary fibrosis
-
Thrall R.S. & Barton R.W. (1984) A comparison of lymphocyte populations in lung tissue and in bronchoalveolar lavage fluid of rats at various times during the development of bleomycin-induced pulmonary fibrosis. Am. Rev. Respir. Dis. 129, 279-283.
-
(1984)
Am. Rev. Respir. Dis.
, vol.129
, pp. 279-283
-
-
Thrall, R.S.1
Barton, R.W.2
-
41
-
-
0002049177
-
The effect of T cell depletion on the development of bleomycin-induced pulmonary fibrosis in the rat
-
Thrall R.S., Lovely E.J.I., Baron R.W., McCormick J.R., Phan S.H., Ward P.A. (1980) The effect of T cell depletion on the development of bleomycin-induced pulmonary fibrosis in the rat. Am. Rev. Respir. Dis. 121(s), 99.
-
(1980)
Am. Rev. Respir. Dis.
, vol.121
, Issue.S
, pp. 99
-
-
Thrall, R.S.1
Lovely, E.J.I.2
Baron, R.W.3
McCormick, J.R.4
Phan, S.H.5
Ward, P.A.6
-
42
-
-
0018427873
-
The effect of antilymphocyte globulin on the development of bleomycin-induced pulmonary fibrosis in the rat
-
Thrall R.S., McCormick J.R., Jack R.M., Phan S.H., Ward P.A. (1979) The effect of antilymphocyte globulin on the development of bleomycin-induced pulmonary fibrosis in the rat. Am. Rev. Respir. Dis. 119(s), 83.
-
(1979)
Am. Rev. Respir. Dis.
, vol.119
, Issue.S
, pp. 83
-
-
Thrall, R.S.1
McCormick, J.R.2
Jack, R.M.3
Phan, S.H.4
Ward, P.A.5
-
43
-
-
0037162961
-
Halofuginone does not reduce fibrosis in bleomycin-induced lung injury
-
Tzurel A., Segel M.J., Or R., Goldstein R.H., Breuer R. (2002) Halofuginone does not reduce fibrosis in bleomycin-induced lung injury. Life Sci. 71, 1599-1606.
-
(2002)
Life Sci.
, vol.71
, pp. 1599-1606
-
-
Tzurel, A.1
Segel, M.J.2
Or, R.3
Goldstein, R.H.4
Breuer, R.5
-
44
-
-
0028041259
-
Mechanisms of dichotomous action of IL-2-pseudomonas exotoxin 40 (IL-2-PE40) on cell-mediated and humoral immune response
-
Volk H.D., Muller S., Yarkoni S., Diamantstein T., Lorberboum-Galski H. (1994) Mechanisms of dichotomous action of IL-2-pseudomonas exotoxin 40 (IL-2-PE40) on cell-mediated and humoral immune response. J. Immunol. 153, 2497-2505.
-
(1994)
J. Immunol.
, vol.153
, pp. 2497-2505
-
-
Volk, H.D.1
Muller, S.2
Yarkoni, S.3
Diamantstein, T.4
Lorberboum-Galski, H.5
-
45
-
-
0027252110
-
The IL-2/IL-2 receptor system: A target for rational immune intervention
-
Waldmann T.A. (1993) The IL-2/IL-2 receptor system: a target for rational immune intervention. Immunol. Today 14, 264-270.
-
(1993)
Immunol. Today
, vol.14
, pp. 264-270
-
-
Waldmann, T.A.1
-
46
-
-
0029853311
-
Contribution of T lymphocytes to the development of bleomycin-induced pulmonary fibrosis
-
Zhu J., Cohen D.A., Goud S.N., Kaplan A.M. (1996) Contribution of T lymphocytes to the development of bleomycin-induced pulmonary fibrosis. Ann. N Y Acad. Sci. 796, 194-202.
-
(1996)
Ann. N Y Acad. Sci.
, vol.796
, pp. 194-202
-
-
Zhu, J.1
Cohen, D.A.2
Goud, S.N.3
Kaplan, A.M.4
|