All-trans-retinoic acid (ATRA) is of no benefit in bleomycin-induced lung injury

Pulmonary Pharmacology and Therapeutics

Volumn 14, Issue 5, 2001, Pages 403-407

  Segel, Michael J ^a   Or, Reuven ^b   Tzurel, Anat ^a   Lucey, Edgar C ^b   Goldstein, Ronald H ^b   Izbicki, Gabriel ^a   Breuer, Raphael ^a,b  

^a HADASSAH HEBREW UNIVERSITY MEDICAL CENTER   (Israel)

^b HEBREW UNIVERSITY   (Israel)

Author keywords

ATRA; Bleomycin; Fibrosis; Interstitial lung disease; Rat

Indexed keywords

BLEOMYCIN; RETINOIC ACID;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; HISTOPATHOLOGY; INTERSTITIAL LUNG DISEASE; LEUKOCYTE DIFFERENTIAL COUNT; LUNG FIBROSIS; LUNG INJURY; LUNG LAVAGE; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; TREATMENT FAILURE;

EID: 0034776350     PISSN: 10945539     EISSN: None     Source Type: Journal    
DOI: 10.1006/pupt.2001.0300     Document Type: Article

References (32)

1. A clinician's view
2. Idiopathic pulmonary fibrosis: Clinical relevance of pathologic classification
3. Chronic interstitial pulmonary fibrosis produced in hamsters by endotracheal bleomycin: Pathology and serology
4. Biochemical and structural alterations of hamster lungs in response to intratracheal administration of bleomycin
5. Chronic interstitial pulmonary fibrosis produced in hamsters by endotracheal bleomycin: Lung volumes, volume-pressure relations, carbon monoxide uptake, and arterial blood gas studied
6. Retinoic acid-induced inhibition of type I collagen gene expression by human lung fibroblasts
7. Retinoic acid inhibition of transforming growth factor-beta-induced collagen production by human lung fibroblasts
8. Modulation of the anchorage-independent phenotype of human lung fibroblasts obtained from fibrotic tissue following culture with retinoid and corticosteroid
9. Suppression of experimental hepatic fibrosis by administration of vitamin A
10. Evidence for anti-inflammatory activities of oral synthetic retinoids: Experimental findings and clinical experience
11. All-trans-retinoic acid in acute promyelocytic leukemia. II. In vitro studies: Structure-function relationship
12. Proof of differentiative mode of action of all-trans-retinoic acid in acute promyelocytic leukemia using X-linked clonal analysis
13. Effect of immunomodulators on bleomycin-induced lung injury
14. The effect of enoxaparin on bleomycin-induced lung injury in mice
15. Superoxide dismutase inhibits radiation lung injury in hamsters
16. Modulation of collagen synthesis by fat-storing cells, isolated from CC14 or vitamin A-treated rats
17. Retinoid effects on fibroblast proliferation and collagen synthesis in vitro and on fibrotic disease in vivo
18. Retinoids inhibit the respiratory burst and degranulation of stimulated human polymorphonuclear leukocytes
19. Trans-retinoic acid blocks platelet-derived factor-BB-induced expression of the murine monocyte chemoattractant-1 gene by blocking the assembly of a promoter proximal Spl binding site
20. Retinoic acid potentiates TNF-alpha-induced ICAM-1 expression in normal human epidermal keratinocytes
21. Tumor necrosis factor/cachectin plays a key role in bleomycin-induced pneumopathy and fibrosis
22. Specific inhibitors of platelet-derived growth factor or epidermal growth factor receptor tyrosine kinase reduce pulmonary fibrosis in rats
23. Vitamin A pretreatment and bleomycin induced rat lung injury
24. Postnatal treatment with retinoic acid increases the number of pulmonary alveoli in rats
25. Differentiation therapy of acute promyelocytic leukemia with tretinoin (all frans retinoic acid)
26. All-trans-retinoic acid in acute promyelocytic leukemia
27. Retinoic acid treatment abrogates elastase-induced pulmonary emphysema in rats
28. Alveolar epithelial cells in pulmonary fibrosis
29. Relationship of alveolar epithelial injury and repair to the induction of pulmonary fibrosis
30. Role of the epithelium in lung repair
31. Retinoic acid inhibits interleukin-l-induced cytokine synthesis in human monocytes