3,4-Methylenedioxymethamphetamine increases pro-interleukin-1β production and caspase-1 protease activity in frontal cortex, but not in hypothalamus, of Dark Agouti rats: Role of interleukin-1β in neurotoxicity

Neuroscience

Volumn 135, Issue 4, 2005, Pages 1095-1105

  O'Shea, E ^a   Sanchez, V ^a   Orio, L ^a   Escobedo, I ^a   Green, A R ^b   Colado, M I ^a  

^a UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

^b DE MONTFORT UNIVERSITY   (United Kingdom)

Author keywords

5 HT neurotoxicity; Caspase 1 protease; Frontal cortex; Hypothalamus; MDMA; Pro IL 1

Indexed keywords

3,4 METHYLENEDIOXYMETHAMPHETAMINE; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; SEROTONIN; SODIUM CHLORIDE;

ANIMAL EXPERIMENT; ARTICLE; BODY TEMPERATURE; COMPARATIVE STUDY; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME ACTIVATION; ENZYME ACTIVITY; FRONTAL CORTEX; HIPPOCAMPUS; HYPERTHERMIA; HYPOTHALAMUS; IMMUNOREACTIVITY; MALE; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALS; BLOTTING, WESTERN; CASPASE 1; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; FEVER; FRONTAL LOBE; HALLUCINOGENS; HYDROXYINDOLEACETIC ACID; HYPOTHALAMUS; INJECTIONS, INTRAVENTRICULAR; INTERLEUKIN-1; N-METHYL-3,4-METHYLENEDIOXYAMPHETAMINE; NEURONS; PEPTIDE HYDROLASES; PROTEIN PRECURSORS; RATS; SEROTONIN;

EID: 26244462829     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2005.06.084     Document Type: Article

References (50)

1. H.A. Baldwin, J.L. Williams, M. Snares, T. Ferreira, A.J. Cross, A.R. Green Attenuation by chlormethiazole administration of the rise in extracellular amino acids following focal ischaemia in the cerebral cortex of the rat Br J Pharmacol 112 1994 188 194
2. H.U. Beuscher, C. Gunther, M. Rollinghoff IL-1 beta is secreted by activated murine macrophages as biologically inactive precursor J Immunol 144 1990 2179 2183
3. J.A. Boulant Role of preoptic-anterior hypothalamus in thermoregulation and fever Clin Infect Dis 31 Suppl 5 2000 S157 S161
4. H.W. Broening, J.F. Bowyer, W. Slikker Jr Age-dependent sensitivity of rats to the long-term effects of the serotonergic neurotoxicant (±)-3,4-methylenedioxymethamphetamine (MDMA) correlates with the magnitude of the MDMA-induced thermal response J Pharmacol Exp Ther 275 1995 325 333
5. P.L. Brown, E.A. Kiyatkin Brain hyperthermia induced by MDMA (ecstasy) modulation by environmental conditions Eur J Neurosci 20 2004 51 58
6. P.L. Brown, R.A. Wise, E.A. Kiyatkin Brain hyperthermia is induced by methamphetamine and exacerbated by social interaction J Neurosci 23 2003 3924 3929
7. Y. Chakfe, R. Seguin, J.P. Antel, C. Morissette, D. Malo, D. Henderson, P. Seguela ADP and AMP induce interleukin-1beta release from microglial cells through activation of ATP-primed P2X7 receptor channels J Neurosci 22 2002 3061 3069
8. N. Chauvet, K. Palin, D. Verrier, S. Poole, R. Dantzer, J. Lestage Rat microglial cells secrete predominantly the precursor of interleukin-1beta in response to lipopolysaccharide Eur J Neurosci 14 2001 609 617
9. M.I. Colado, E. O'Shea, R. Granados, T.K. Murray, A.R. Green In vivo evidence for free radical involvement in the degeneration of rat brain 5-HT following administration of MDMA ('ecstasy') and p-chloroamphetamine but not the degeneration following fenfluramine Br J Pharmacol 121 1997 889 900
10. M.I. Colado, B. Esteban, E. O'Shea, R. Granados, A.R. Green Studies on the neuroprotective effect of pentobarbitone on MDMA-induced neurodegeneration Psychopharmacology 142 1999 421 425
11. M.I. Colado, E. O'Shea, R. Granados, B. Esteban, A.B. Martin, A.R. Green Studies on the role of dopamine in the degeneration of 5-HT nerve endings in the brain of Dark Agouti rats following 3,4-methylenedioxymethamphetamine (MDMA or 'ecstasy') administration Br J Pharmacol 126 1999 911 926
12. M.I. Colado, R. Granados, E. O'Shea, B. Esteban, A.R. Green Role of hyperthermia in the protective action of clomethiazole against MDMA ('ecstasy')-induced neurodegeneration, comparison with the novel NMDA channel blocker AR-R15896AR Br J Pharmacol 124 1998 479 484
13. G.M. Farfel, G.L. Vosmer, L.S. Seiden The N-methyl-D-aspartate antagonist MK-801 protects against serotonin depletions induced by methamphetamine, 3,4-methylenedioxymethamphetamine and p-chloroamphetamine Brain Res 595 1992 121 127
14. G.M. Farfel, L.S. Seiden Role of hyperthermia in the mechanism of protection against serotonergic toxicity. I. Experiments using 3,4-methylendioxymethamphetamine, dizocilpine, CGS 19755 and NBQX J Pharmacol Exp Ther 272 1995 860 867
15. D. Ferrari, M. Villalba, P. Chiozzi, S. Falzoni, P. Ricciardi-Castagnoli, F. Di Virgilio Mouse microglial cells express a plasma membrane pore gated by extracellular ATP J Immunol 156 1996 1531 1539
16. D. Giulian, T.J. Baker, L.C. Shih, L.B. Lachman Interleukin 1 of the central nervous system is produced by ameboid microglia J Exp Med 164 1986 594 604
17. P. Hagan, S. Poole, A.F. Bristow Endotoxin-stimulated production of rat hypothalamic interleukin-1 beta in vivo and in vitro, measured by specific immunoradiometric assay J Mol Endocrinol 11 1993 31 36
18. D.J. Hazuda, J. Strickler, F. Kueppers, P.L. Simon, P.R. Young Processing of precursor interleukin 1 beta and inflammatory disease J Biol Chem 265 1990 6318 6322
19. K.E. Hewitt, A.R. Green Chlormethiazole, dizocilpine and haloperidol prevent the degeneration of serotonergic nerve terminals induced by administration of MDMA ('ecstasy') to rats Neuropharmacology 33 1994 1589 1595
20. E.A. Kiyatkin, P.L. Brown Modulation of physiological brain hyperthermia by environmental temperature and impaired blood outflow in rats Physiol Behav 83 2004 467 474
21. M.J. Kluger Fever role of pyrogens and cryogens Physiol Rev 71 1991 93 127
22. J.F.R. König, R.A. Klippel The rat brain. A stereotaxic atlas of the forebrain and lower parts of the brain stem 1963 Robert E. Krieger Publishing Co. Inc New York
23. J.M. Krueger, J. Fang, M.K. Hansen, J. Zhang, F. Obal Jr Humoral regulation of sleep News Physiol Sci 13 1998 189 194
24. C. Lindberg, C. Eriksson, A.M. Van Dam, B. Winblad, M. Schultzberg Neuronal expression of caspase-1 immunoreactivity in the rat central nervous system J Neuroimmunol 146 2004 99 113
25. O.H. Lowry, N.J. Rosebrough, A.L. Farr, R.J. Randall Protein measurement with the Folin phenol reagent J Biol Chem 193 1951 265 275
26. J.E. Malberg, K.E. Sabol, L.S. Seiden Co-administration of MDMA with drugs that protect against MDMA neurotoxicity produces different effects on body temperature in the rat J Pharmacol Exp Ther 278 1996 258 267
27. J.E. Malberg, L.S. Seiden Small changes in ambient temperature cause large changes in 3,4-methylenedioxymethamphetamine (MDMA)-induced serotonin neurotoxicity and core body temperature in the rat J Neurosci 18 1998 5086 5094
28. C.J. March, B. Mosley, A. Larsen, D.P. Cerretti, G. Braedt, V. Price, S. Gillis, C.S. Henney, S.R. Kronheim, K. Grabstein Cloning, sequence and expression of two distinct human interleukin-1 complementary DNAs Nature 315 1985 641 647
29. D.O. McCarthy, M.J. Kluger, A.J. Vander Suppression of food intake during infection is interleukin-1 involved? Am J Clin Nutr 42 1985 1179 1182
30. C. Miossec, M.C. Decoen, L. Durand, F. Fassy, A. Diu-Hercend Use of monoclonal antibodies to study interleukin-1 beta-converting enzyme expression only precursor forms are detected in interleukin-1 beta-secreting cells Eur J Immunol 26 1996 1032 1042
31. K.T. Nguyen, T. Deak, S.M. Owens, T. Kohno, M. Fleshner, L.R. Watkins, S.F. Maier Exposure to acute stress induces brain interleukin-1beta protein in the rat J Neurosci 18 1998 2239 2246
32. E. O'Hearn, G. Battaglia, E.B. De Souza, M.J. Kuhar, M.E. Molliver Methylenedioxyamphetamine (MDA) and methylenedioxymethamphetamine (MDMA) cause selective ablation of serotonergic axon terminals in forebrain immunocytochemical evidence for neurotoxicity J Neurosci 8 1988 2788 2803
33. L. Orio, E. O'Shea, V. Sanchez, J.M. Pradillo, I. Escobedo, J. Camarero, M.A. Moro, A.R. Green, M.I. Colado 3,4-Methylenedioxymethamphetamine increases interleukin-1beta levels and activates microglia in rat brain studies on the relationship with acute hyperthermia and 5-HT depletion J Neurochem 89 2004 1445 1453
34. E. O'Shea, I. Escobedo, L. Orio, V. Sanchez, M. Navarro, A.R. Green, M.I. Colado Elevation of ambient room temperature has differential effects on MDMA-induced 5-HT and dopamine release in striatum and nucleus accumbens of rats Neuropsychopharmacology 30 2005 1312 1323
35. C.R. Plata-Salaman, Y. Oomura, Y. Kai Tumor necrosis factor and interleukin-1 beta suppression of food intake by direct action in the central nervous system Brain Res 448 1988 106 114
36. N. Quan, Z. Zhang, M. Emery, R. Bonsall, J.M. Weiss Detection of interleukin-1 bioactivity in various brain regions of normal healthy rats Neuroimmunomodulation 3 1996 47 55
37. N. Quan, M. Whiteside, M. Herkenham Time course and localization patterns of interleukin-1beta messenger RNA expression in brain and pituitary after peripheral administration of lipopolysaccharide Neuroscience 83 1998 281 293
38. A. Rubartelli, F. Cozzolino, M. Talio, R. Sitia A novel secretory pathway for interleukin-1 beta, a protein lacking a signal sequence EMBO J 9 1990 1503 1510
39. V. Sanchez, J. Camarero, E. Esteban, M.J. Peter, A.R. Green, M.I. Colado The mechanisms involved in the long-lasting neuroprotective effect of fluoxetine against MDMA ('ecstasy')-induced degeneration of 5-HT nerve endings in rat brain Br J Pharmacol 134 2001 46 57
40. V. Sanchez, E. O'Shea, K.S. Saadat, J.M. Elliott, M.I. Colado, A.R. Green Effect of repeated ('binge') dosing of MDMA to rats housed at normal and high temperature on neurotoxic damage to cerebral 5-HT and dopamine neurones J Psychopharmacol 18 2004 412 416
41. J.M. Sanz, F. Di Virgilio Kinetics and mechanism of ATP-dependent IL-1 beta release from microglial cells J Immunol 164 2000 4893 4898
42. V.L. Savchenko, J.A. McKanna, I.R. Nikonenko, G.G. Skibo Microglia and astrocytes in the adult rat brain comparative immunocytochemical analysis demonstrates the efficacy of lipocortin 1 immunoreactivity Neuroscience 96 2000 195 203
43. 2 receptors Brain Res 529 1990 85 90
44. J. Sharkey, D.E. McBean, P.A. Kelly Alterations in hippocampal function following repeated exposure to the amphetamine derivative methylenedioxymethamphetamine ('ecstasy') Psychopharmacology 105 1991 113 118
45. Singer II, S. Scott, J. Chin, E.K. Bayne, G. Limjuco, J. Weidner, D.K. Miller, K. Chapman, M.J. Kostura The interleukin-1 beta-converting enzyme (ICE) is localized on the external cell surface membranes and in the cytoplasmic ground substance of human monocytes by immuno-electron microscopy J Exp Med 182 1995 1447 1459
46. J. Suttles, J.G. Giri, S.B. Mizel IL-1 secretion by macrophages. Enhancement of IL-1 secretion and processing by calcium ionophores J Immunol 144 1990 175 182
47. N.A. Thornberry, H.G. Bull, J.R. Calaycay, K.T. Chapman, A.D. Howard, M.J. Kostura, D.K. Miller, S.M. Molineaux, J.R. Weidner, J. Aunins A novel heterodimeric cysteine protease is required for interleukin-1 beta processing in monocytes Nature 356 1992 768 774
48. G. Tringali, C. Mancuso, A. Mirtella, G. Pozzoli, L. Parente, P. Preziosi, P. Navarra Evidence for the neuronal origin of immunoreactive interleukin-1 beta released by rat hypothalamic explants Neurosci Lett 219 1996 143 146
49. G. Tringali, A. Mirtella, C. Mancuso, G. Guerriero, P. Preziosi, P. Navarra The release of immunoreactive interleukin-1 beta from rat hypothalamic explants is modulated by neurotransmitters and corticotropin-releasing hormone Pharmacol Res 36 1997 269 273
50. A.M. Van Dam, J. Bauer, F.J. Tilders, F. Berkenbosch Endotoxin-induced appearance of immunoreactive interleukin-1 beta in ramified microglia in rat brain a light and electron microscopic study Neuroscience 65 1995 815 826