-
1
-
-
1642304059
-
Systemic treatment of advanced colorectal carcinoma
-
H.W. van Laarhoven, and C.J. Punt Systemic treatment of advanced colorectal carcinoma Eur J Gastroenterol Hepatol 16 3 2004 283 289
-
(2004)
Eur J Gastroenterol Hepatol
, vol.16
, Issue.3
, pp. 283-289
-
-
Van Laarhoven, H.W.1
Punt, C.J.2
-
3
-
-
0037106273
-
Targeting the epidermal growth factor receptor for cancer therapy
-
J. Mendelsohn Targeting the epidermal growth factor receptor for cancer therapy J Clin Oncol 20 2002 1S 13S
-
(2002)
J Clin Oncol
, vol.20
-
-
Mendelsohn, J.1
-
4
-
-
0345016002
-
Small-molecule epidermal growth factor receptor tyrosine kinase inhibitors
-
Janmaat, and Giaccone Small-molecule epidermal growth factor receptor tyrosine kinase inhibitors The Oncologist 8 2003 576 586
-
(2003)
The Oncologist
, vol.8
, pp. 576-586
-
-
Janmaat1
Giaccone2
-
5
-
-
0038514987
-
Development of ZD1839 in colorectal cancer
-
E.C. Douglass Development of ZD1839 in colorectal cancer Semin Oncol 30 3 Suppl 6 2003 17 22
-
(2003)
Semin Oncol
, vol.30
, Issue.3 SUPPL. 6
, pp. 17-22
-
-
Douglass, E.C.1
-
6
-
-
0345734200
-
Synergistic interaction between the EGFR tyrosine kinase inhibitor gefitinib ("Iressa") and the DNA topoisomerase I inhibitor CPT-11 (irinotecan) in human colorectal cancer cells
-
F. Koizumi, F. Kanzawa, and Y. Ueda Synergistic interaction between the EGFR tyrosine kinase inhibitor gefitinib ("Iressa") and the DNA topoisomerase I inhibitor CPT-11 (irinotecan) in human colorectal cancer cells Int J Cancer 108 3 2004 464 472
-
(2004)
Int J Cancer
, vol.108
, Issue.3
, pp. 464-472
-
-
Koizumi, F.1
Kanzawa, F.2
Ueda, Y.3
-
7
-
-
2942560684
-
The schedule-dependent enhanced cytotoxic activity of 7-ethyl-10-hydroxy-camptothecin (SN-38) in combination with Gefitinib (Iressa, ZD1839)
-
A. Azzariti, J.M. Xu, and L. Porcelli The schedule-dependent enhanced cytotoxic activity of 7-ethyl-10-hydroxy-camptothecin (SN-38) in combination with Gefitinib (Iressa, ZD1839) Biochem Pharmacol 68 1 2004 135 144
-
(2004)
Biochem Pharmacol
, vol.68
, Issue.1
, pp. 135-144
-
-
Azzariti, A.1
Xu, J.M.2
Porcelli, L.3
-
8
-
-
0345375552
-
The effect of gefitinib (Iressa, ZD1839) in combination with oxaliplatin is schedule-dependent in colon cancer cell lines
-
J.M. Xu, A. Azzariti, and G. Colucci The effect of gefitinib (Iressa, ZD1839) in combination with oxaliplatin is schedule-dependent in colon cancer cell lines Cancer Chemother Pharmacol 52 6 2003 442 448
-
(2003)
Cancer Chemother Pharmacol
, vol.52
, Issue.6
, pp. 442-448
-
-
Xu, J.M.1
Azzariti, A.2
Colucci, G.3
-
9
-
-
12444330870
-
A pharmacodynamic study of the epidermal growth factor receptor tyrosine kinase inhibitor ZD1839 in metastatic colorectal cancer patients
-
M. Daneshmand, D.A. Parolin, and H.W. Hirte A pharmacodynamic study of the epidermal growth factor receptor tyrosine kinase inhibitor ZD1839 in metastatic colorectal cancer patients Clin Cancer Res 9 7 2003 2457 2464
-
(2003)
Clin Cancer Res
, vol.9
, Issue.7
, pp. 2457-2464
-
-
Daneshmand, M.1
Parolin, D.A.2
Hirte, H.W.3
-
10
-
-
0346057793
-
Extensive experience of disease control with gefitinib and the role of prognostic markers
-
H. Cortes-Funes, and H. Soto Parra Extensive experience of disease control with gefitinib and the role of prognostic markers Br J Cancer 89 2003 S3 S8
-
(2003)
Br J Cancer
, vol.89
-
-
Cortes-Funes, H.1
Soto Parra, H.2
-
11
-
-
0037295398
-
Studies with ZD1839 in preclinical models
-
F.M. Sirotnak Studies with ZD1839 in preclinical models Semin Oncol 30 2003 12 20
-
(2003)
Semin Oncol
, vol.30
, pp. 12-20
-
-
Sirotnak, F.M.1
-
12
-
-
0035174127
-
Pharmacodynamic studies with the epidermal growth factor receptor tyrosine kinase inhibitor ZD1839
-
J. Albanell, F. Rojo, and J. Baselga Pharmacodynamic studies with the epidermal growth factor receptor tyrosine kinase inhibitor ZD1839 Semin Oncol 28 5 Suppl 16 2001 56 66
-
(2001)
Semin Oncol
, vol.28
, Issue.5 SUPPL. 16
, pp. 56-66
-
-
Albanell, J.1
Rojo, F.2
Baselga, J.3
-
13
-
-
0037029703
-
Influence of epidermal growth factor receptor (EGFR), p53 and intrinsic MAP kinase pathway status of tumour cells on the antiproliferative effect of ZD1839 ("Iressa")
-
N. Magne, J.L. Fischel, and A. Dubreuil Influence of epidermal growth factor receptor (EGFR), p53 and intrinsic MAP kinase pathway status of tumour cells on the antiproliferative effect of ZD1839 ("Iressa") Br J Cancer 86 9 2002 1518 1523
-
(2002)
Br J Cancer
, vol.86
, Issue.9
, pp. 1518-1523
-
-
Magne, N.1
Fischel, J.L.2
Dubreuil, A.3
-
14
-
-
2342471392
-
Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib
-
T.J. Lynch, D.W. Bell, and R. Sordella Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib New Engl J Med 350 21 2004 2129 2139
-
(2004)
New Engl J Med
, vol.350
, Issue.21
, pp. 2129-2139
-
-
Lynch, T.J.1
Bell, D.W.2
Sordella, R.3
-
15
-
-
0027262225
-
Characterization of the DiFi rectal carcinoma cell line derived from a familial adenomatous polyposis patient
-
M. Olive, S. Untawale, and R.J. Coffey Characterization of the DiFi rectal carcinoma cell line derived from a familial adenomatous polyposis patient In vitro cell dev biol 29 1993 239 248
-
(1993)
In Vitro Cell Dev Biol
, vol.29
, pp. 239-248
-
-
Olive, M.1
Untawale, S.2
Coffey, R.J.3
-
16
-
-
0036006453
-
Prostaglandin E2 transactivates EGF receptor: A novel mechanism for promoting colon cancer growth and gastrointestinal hypertrophy
-
R. Pai, B. Soreghan, and I.L. Szabo Prostaglandin E2 transactivates EGF receptor: a novel mechanism for promoting colon cancer growth and gastrointestinal hypertrophy Nat Med 8 3 2002 289 293
-
(2002)
Nat Med
, vol.8
, Issue.3
, pp. 289-293
-
-
Pai, R.1
Soreghan, B.2
Szabo, I.L.3
-
17
-
-
2442692682
-
Protease-activated receptor 2 in colon cancer: Trypsin-induced MAPK phosphorylation and cell proliferation are mediated by epidermal growth factor receptor transactivation
-
D. Darmoul, V. Gratio, and H. Devaud Protease-activated receptor 2 in colon cancer: trypsin-induced MAPK phosphorylation and cell proliferation are mediated by epidermal growth factor receptor transactivation J Biol Chem 279 20 2004 20927 20934
-
(2004)
J Biol Chem
, vol.279
, Issue.20
, pp. 20927-20934
-
-
Darmoul, D.1
Gratio, V.2
Devaud, H.3
-
18
-
-
0028969852
-
Apoptosis induced by an anti-epidermal growth factor receptor monoclonal antibody in a human colorectal carcinoma cell line and its delay by insulin
-
X. Wu, Z. Fan, and H. Masui Apoptosis induced by an anti-epidermal growth factor receptor monoclonal antibody in a human colorectal carcinoma cell line and its delay by insulin J Clin Invest 95 4 1995 1897 1905
-
(1995)
J Clin Invest
, vol.95
, Issue.4
, pp. 1897-1905
-
-
Wu, X.1
Fan, Z.2
Masui, H.3
-
19
-
-
10744219895
-
Calgranulins in cystic fluid and serum from patients with ovarian carcinomas
-
H.W. Ott, H. Lindner, and B. Sarg Calgranulins in cystic fluid and serum from patients with ovarian carcinomas Cancer Res 63 21 2003 7507 7514
-
(2003)
Cancer Res
, vol.63
, Issue.21
, pp. 7507-7514
-
-
Ott, H.W.1
Lindner, H.2
Sarg, B.3
-
20
-
-
2442480522
-
Epidermal growth factor receptor, c-MET, beta-catenin, and p53 expression as prognostic indicators in stage II colon cancer: A tissue microarray study
-
M.B. Resnick, J. Routhier, and T. Konkin Epidermal growth factor receptor, c-MET, beta-catenin, and p53 expression as prognostic indicators in stage II colon cancer: a tissue microarray study Clin Cancer Res 10 9 2004 3069 3075
-
(2004)
Clin Cancer Res
, vol.10
, Issue.9
, pp. 3069-3075
-
-
Resnick, M.B.1
Routhier, J.2
Konkin, T.3
-
21
-
-
1842633680
-
Gefitinib, a novel, orally administered agent for the treatment of cancer
-
M. Ranson, and S. Wardell Gefitinib, a novel, orally administered agent for the treatment of cancer J Clin Pharm Ther 29 2 2004 95 103
-
(2004)
J Clin Pharm Ther
, vol.29
, Issue.2
, pp. 95-103
-
-
Ranson, M.1
Wardell, S.2
-
22
-
-
0037499945
-
Response to epidermal growth factor receptor inhibitors in non-small cell lung cancer cells: Limited antiproliferative effects and absence of apoptosis associated with persistent activity of extracellular signal-regulated kinase or Akt kinase pathways
-
M.L. Janmaat, F.A. Kruyt, and J.A. Rodriguez Response to epidermal growth factor receptor inhibitors in non-small cell lung cancer cells: limited antiproliferative effects and absence of apoptosis associated with persistent activity of extracellular signal-regulated kinase or Akt kinase pathways Clin Cancer Res 9 6 2003 2316 2326
-
(2003)
Clin Cancer Res
, vol.9
, Issue.6
, pp. 2316-2326
-
-
Janmaat, M.L.1
Kruyt, F.A.2
Rodriguez, J.A.3
-
23
-
-
11144333540
-
Absence of EGFR mutation in the kinase domain in common human cancers besides non-small cell lung cancer
-
J.W. Lee, Y.H. Soung, and S.Y. Kim Absence of EGFR mutation in the kinase domain in common human cancers besides non-small cell lung cancer Int J Cancer 113 3 2005 510 511
-
(2005)
Int J Cancer
, vol.113
, Issue.3
, pp. 510-511
-
-
Lee, J.W.1
Soung, Y.H.2
Kim, S.Y.3
-
24
-
-
0034489892
-
PGP9.5 as a prognostic factor in pancreatic cancer
-
E. Tezel, K. Hibi, and T. Nagasaka PGP9.5 as a prognostic factor in pancreatic cancer Clin Cancer Res 6 12 2000 4764 4767
-
(2000)
Clin Cancer Res
, vol.6
, Issue.12
, pp. 4764-4767
-
-
Tezel, E.1
Hibi, K.2
Nagasaka, T.3
-
25
-
-
0035503380
-
Proteomics-based identification of protein gene product 9.5 as a tumor antigen that induces a humoral immune response in lung cancer
-
F. Brichory, D. Beer, and F. Le Naour Proteomics-based identification of protein gene product 9.5 as a tumor antigen that induces a humoral immune response in lung cancer Cancer Res 61 21 2001 7908 7912
-
(2001)
Cancer Res
, vol.61
, Issue.21
, pp. 7908-7912
-
-
Brichory, F.1
Beer, D.2
Le Naour, F.3
-
26
-
-
0036157539
-
PGP9.5 as a marker for invasive colorectal cancer
-
T. Yamazaki, and K. Hibi PGP9.5 as a marker for invasive colorectal cancer Clin Cancer Res 8 1 2002 192 195
-
(2002)
Clin Cancer Res
, vol.8
, Issue.1
, pp. 192-195
-
-
Yamazaki, T.1
Hibi, K.2
-
27
-
-
12444269118
-
Discovery of inhibitors that elucidate the role of UCH-L1 activity in the H1299 lung cancer cell line
-
Y. Liu, and H.A. Lashuel Discovery of inhibitors that elucidate the role of UCH-L1 activity in the H1299 lung cancer cell line Chem Biol 10 9 2003 837 846
-
(2003)
Chem Biol
, vol.10
, Issue.9
, pp. 837-846
-
-
Liu, Y.1
Lashuel, H.A.2
-
28
-
-
85047695545
-
Interaction and colocalization of PGP9.5 with JAB1 and p27(Kip1)
-
O.L. Caballero, V. Resto, and M. Patturajan Interaction and colocalization of PGP9.5 with JAB1 and p27(Kip1) Oncogene 21 19 2002 3003 3010
-
(2002)
Oncogene
, vol.21
, Issue.19
, pp. 3003-3010
-
-
Caballero, O.L.1
Resto, V.2
Patturajan, M.3
-
29
-
-
7944239349
-
Expression of protein gene product 9.5 (PGP9.5)/ubiquitin-C-terminal hydrolase 1 (UCHL-1) in human myeloma cells
-
T. Otsuki, K. Yata, and A. Takata-Tomokuni Expression of protein gene product 9.5 (PGP9.5)/ubiquitin-C-terminal hydrolase 1 (UCHL-1) in human myeloma cells Br J Haematol 127 3 2004 292 298
-
(2004)
Br J Haematol
, vol.127
, Issue.3
, pp. 292-298
-
-
Otsuki, T.1
Yata, K.2
Takata-Tomokuni, A.3
-
30
-
-
0034629485
-
Reversible G(1) arrest induced by inhibition of the epidermal growth factor receptor tyrosine kinase requires up-regulation of p27(KIP1) independent of MAPK activity
-
D. Busse, R.S. Doughty, and T.T. Ramsey Reversible G(1) arrest induced by inhibition of the epidermal growth factor receptor tyrosine kinase requires up-regulation of p27(KIP1) independent of MAPK activity J Biol Chem 275 10 2000 6987 6995
-
(2000)
J Biol Chem
, vol.275
, Issue.10
, pp. 6987-6995
-
-
Busse, D.1
Doughty, R.S.2
Ramsey, T.T.3
-
31
-
-
0038487676
-
Reconstitution of galectin-3 alters glutathione content and potentiates TRAIL-induced cytotoxicity by dephosphorylation of Akt
-
Y.J. Lee, Y.K. Song, and J.J. Song Reconstitution of galectin-3 alters glutathione content and potentiates TRAIL-induced cytotoxicity by dephosphorylation of Akt Exp Cell Res 288 1 2003 21 34
-
(2003)
Exp Cell Res
, vol.288
, Issue.1
, pp. 21-34
-
-
Lee, Y.J.1
Song, Y.K.2
Song, J.J.3
-
32
-
-
0035877114
-
Role of glutathione S-transferase P1, P-glycoprotein and multidrug resistance-associated protein 1 in acquired doxorubicin resistance
-
A. Harbottle, A.K. Daly, and K. Atherton Role of glutathione S-transferase P1, P-glycoprotein and multidrug resistance-associated protein 1 in acquired doxorubicin resistance Int J Cancer 92 6 2001 777 783
-
(2001)
Int J Cancer
, vol.92
, Issue.6
, pp. 777-783
-
-
Harbottle, A.1
Daly, A.K.2
Atherton, K.3
-
33
-
-
0034793821
-
Glutathione S-transferase-pi overexpression is closely associated with K-ras mutation during human colon carcinogenesis
-
K. Miyanishi, and T. Takayama Glutathione S-transferase-pi overexpression is closely associated with K-ras mutation during human colon carcinogenesis Gastroenterology 121 4 2001 865 874
-
(2001)
Gastroenterology
, vol.121
, Issue.4
, pp. 865-874
-
-
Miyanishi, K.1
Takayama, T.2
-
34
-
-
0033896832
-
Glutathione S-transferase p elicits protection against H2O2-induced cell death via coordinated regulation of stress kinases
-
Z. Yin, V.N. Ivanov, and H. Habelhah Glutathione S-transferase p elicits protection against H2O2-induced cell death via coordinated regulation of stress kinases Cancer Res 60 15 2000 4053 4057
-
(2000)
Cancer Res
, vol.60
, Issue.15
, pp. 4053-4057
-
-
Yin, Z.1
Ivanov, V.N.2
Habelhah, H.3
-
35
-
-
0030239495
-
Cellular fatty acid-binding proteins: Their function and physiological significance
-
J.F. Glatz, and G.J. van der Vusse Cellular fatty acid-binding proteins: their function and physiological significance Prog Lipid Res 35 3 1996 243 282
-
(1996)
Prog Lipid Res
, vol.35
, Issue.3
, pp. 243-282
-
-
Glatz, J.F.1
Van Der Vusse, G.J.2
-
36
-
-
0034684231
-
Lipocalins and cancer
-
T. Bratt Lipocalins and cancer Biochim Biophys Acta 1482 1-2 2000 318 326
-
(2000)
Biochim Biophys Acta
, vol.1482
, Issue.1-2
, pp. 318-326
-
-
Bratt, T.1
-
37
-
-
0344131934
-
Increased expression of epidermal fatty acid binding protein, cofilin, and 14-3-3-sigma (stratifin) detected by two-dimensional gel electrophoresis, mass spectrometry and microsequencing of drug-resistant human adenocarcinoma of the pancreas
-
P. Sinha, G. Hutter, and E. Kottgen Increased expression of epidermal fatty acid binding protein, cofilin, and 14-3-3-sigma (stratifin) detected by two-dimensional gel electrophoresis, mass spectrometry and microsequencing of drug-resistant human adenocarcinoma of the pancreas Electrophoresis 20 14 1999 2952 2960
-
(1999)
Electrophoresis
, vol.20
, Issue.14
, pp. 2952-2960
-
-
Sinha, P.1
Hutter, G.2
Kottgen, E.3
-
38
-
-
0035072677
-
Protein kinase inhibitors can suppress stress-induced dissociation of Hsp27
-
K. Kato, H. Ito, and I. Iwamoto Protein kinase inhibitors can suppress stress-induced dissociation of Hsp27 Cell Stress Chaperon 6 1 2001 16 20
-
(2001)
Cell Stress Chaperon
, vol.6
, Issue.1
, pp. 16-20
-
-
Kato, K.1
Ito, H.2
Iwamoto, I.3
-
39
-
-
1242315877
-
HSP27 and HSP70: Potentially oncogenic apoptosis inhibitors
-
C. Garrido, E. Schmitt, and C. Cande HSP27 and HSP70: potentially oncogenic apoptosis inhibitors Cell Cycle 2 6 2003 579 584
-
(2003)
Cell Cycle
, vol.2
, Issue.6
, pp. 579-584
-
-
Garrido, C.1
Schmitt, E.2
Cande, C.3
-
40
-
-
0027366354
-
The small heat shock protein hsp27 is correlated with growth and drug resistance in human breast cancer cell lines
-
S. Oesterreich, C.N. Weng, and M. Qiu The small heat shock protein hsp27 is correlated with growth and drug resistance in human breast cancer cell lines Cancer Res 53 19 1993 4443 4448
-
(1993)
Cancer Res
, vol.53
, Issue.19
, pp. 4443-4448
-
-
Oesterreich, S.1
Weng, C.N.2
Qiu, M.3
-
41
-
-
0035954829
-
Heat shock protein 27 was up-regulated in cisplatin resistant human ovarian tumor cell line and associated with the cisplatin resistance
-
K. Yamamoto, A. Okamoto, and S. Isonishi Heat shock protein 27 was up-regulated in cisplatin resistant human ovarian tumor cell line and associated with the cisplatin resistance Cancer Lett 168 2 2001 173 181
-
(2001)
Cancer Lett
, vol.168
, Issue.2
, pp. 173-181
-
-
Yamamoto, K.1
Okamoto, A.2
Isonishi, S.3
-
42
-
-
0041344614
-
Heat shock protein 27 controls apoptosis by regulating Akt activation
-
M.J. Rane, Y. Pan, and S. Singh Heat shock protein 27 controls apoptosis by regulating Akt activation J Biol Chem 278 30 2003 27828 27835
-
(2003)
J Biol Chem
, vol.278
, Issue.30
, pp. 27828-27835
-
-
Rane, M.J.1
Pan, Y.2
Singh, S.3
-
43
-
-
12144266330
-
Hsp90 restrains ErbB-2/HER2 signaling by limiting heterodimer formation
-
A. Citri, J. Gan, and Y. Mosesson Hsp90 restrains ErbB-2/HER2 signaling by limiting heterodimer formation EMBO Rep 5 12 2004 1165 1170
-
(2004)
EMBO Rep
, vol.5
, Issue.12
, pp. 1165-1170
-
-
Citri, A.1
Gan, J.2
Mosesson, Y.3
-
44
-
-
0141953292
-
Blockade of Hsp27 overcomes Bortezomib/proteasome inhibitor PS-341 resistance in lymphoma cells
-
D. Chauhan, G. Li, and R. Shringarpure Blockade of Hsp27 overcomes Bortezomib/proteasome inhibitor PS-341 resistance in lymphoma cells Cancer Res 63 19 2003 6174 6177
-
(2003)
Cancer Res
, vol.63
, Issue.19
, pp. 6174-6177
-
-
Chauhan, D.1
Li, G.2
Shringarpure, R.3
|