NH2-terminal stabilization of small heat shock protein structure: A comparison of two NH2-terminal deletion mutants of αA-crystallin

Molecular Vision

Volumn 11, Issue , 2005, Pages 641-647

  Yang, Chaoxing ^a   Salerno, John C ^a   Koretz, Jane F ^a  

^a RENSSELAER POLYTECHNIC INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA CRYSTALLIN; CHAPERONE; DITHIOTHREITOL; HEAT SHOCK PROTEIN; INSULIN; MUTANT PROTEIN; TETRAMER;

AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ARTICLE; CONTROLLED STUDY; COOLING; FAST PROTEIN LIQUID CHROMATOGRAPHY; GENE DELETION; MUTAGENESIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN DENATURATION; PROTEIN DOMAIN; PROTEIN FOLDING; PROTEIN STRUCTURE; ROOM TEMPERATURE; STRESS; THERMAL EXPOSURE; ANIMAL; CATTLE; CHEMISTRY; COMPARATIVE STUDY; ESCHERICHIA COLI; GEL CHROMATOGRAPHY; GENE EXPRESSION; GENE VECTOR; GENETICS; POLYACRYLAMIDE GEL ELECTROPHORESIS; POLYMERASE CHAIN REACTION; SITE DIRECTED MUTAGENESIS;

ALPHA-CRYSTALLIN A CHAIN; ANIMALS; CATTLE; CHROMATOGRAPHY, GEL; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ESCHERICHIA COLI; GENE EXPRESSION; GENETIC VECTORS; HEAT-SHOCK PROTEINS; MOLECULAR CHAPERONES; MUTAGENESIS, SITE-DIRECTED; POLYMERASE CHAIN REACTION; PROTEIN FOLDING; SEQUENCE DELETION;

EID: 26244437522     PISSN: 10900535     EISSN: 10900535     Source Type: Journal    
DOI: None     Document Type: Article

References (39)

1. Horwitz J. The function of alpha-crystallin in vision. Semin Cell Dev Biol 2000; 11:53-60.
2. Bron AJ, Vrensen GF, Koretz J, Maraini G, Harding JJ. The ageing lens. Ophthalmologica 2000; 214:86-104.
3. Horwitz J. Alpha-crystallin. Exp Eye Res 2003; 76:145-53.
4. Bhat SP, Horwitz J, Srinivasan A, Ding L. Alpha B-crystallin exists as an independent protein in the heart and in the lens. Eur J Biochem 1991; 202:775-81.
5. Benjamin IJ, Shelton J, Garry DJ, Richardson JA. Temporospatial expression of the small HSP/alpha B-crystallin in cardiac and skeletal muscle during mouse development. Dev Dyn 1997; 208:75-84.
6. Ishiguro Y, Kato K, Akatsuka H, Iwata H, Nagaya M. Chemotherapy-induced expression of alpha B-crystallin in neuroblastoma. Med Pediatr Oncol 1997; 29:11-5.
7. van Sechel AC, Bajramovic JJ, van Stipdonk MJ, Persoon-Deen C, Geutskens SB, van Noort JM. EBV-induced expression and HLA-DR-restricted presentation by human B cells of alpha B-crystallin, a candidate autoantigen in multiple sclerosis. J Immunol 1999; 162:129-35.
8. Tallot P, Grongnet JF, David JC. Dual perinatal and developmental expression of the small heat shock proteins [FC12]aB-crystallin and Hsp27 in different tissues of the developing piglet. Biol Neonate 2003; 83:281-8.
9. de Jong WW, Caspers GJ, Leunissen JA. Genealogy of the alpha-crystallin - small heat-shock protein superfamily. Int J Biol Macromol 1998; 22:151-62.
10. Salerno JC, Eifert CL, Salerno KM, Koretz JF. Structural diversity in the small heat shock protein superfamily: control of aggregation by the N-terminal region. Protein Eng 2003; 16:847-51.
11. Koteiche HA, Mchaourab HS. Folding pattern of the alpha-crystallin domain in alphaA-crystallin determined by site-directed spin labeling. J Mol Biol 1999; 294:561-77.
12. Muchowski PJ, Hays LG, Yates JR 3rd, Clark JI. ATP and the core "alpha-Crystallin" domain of the small heat-shock protein alphaB-crystallin. J Biol Chem 1999; 274:30190-5.
13. Guruprasad K, Kumari K. Three-dimensional models corresponding to the C-terminal domain of human alphaA- and alphaB-crystallins based on the crystal structure of the small heat-shock protein HSP16.9 from wheat. Int J Biol Macromol 2003; 33:107-12.
14. Caspers GJ, Leunissen JA, de Jong WW. The expanding small heat-shock protein family, and structure predictions of the conserved "alpha-crystallin domain". J Mol Evol 1995; 40:238-48.
15. Augusteyn RC, Koretz JF. A possible structure for alpha-crystallin. FEBS Lett 1987; 222:1-5.
16. Koretz JF, Augusteyn RC. Electron microscopy of native and reconstituted alpha crystallin aggregates. Curr Eye Res 1988; 7:25-30.
17. Radlick LW, Koretz JF. Biophysical characterization of alpha-crystallin aggregates: validation of the micelle hypothesis. Biochim Biophys Acta 1992; 1120:193-200.
18. Doss EW, Ward KA, Koretz JF. Preliminary studies on the aggregation process of alpha-crystallin. Exp Eye Res 1997; 65:255-66.
19. Wissing D, Jaattela M. HSP27 and HSP70 increase the survival of WEHI-S cells exposed to hyperthermia. Int J Hyperthermia 1996; 12:125-38.
20. Martin JL, Mestril R, Hilal-Dandan R, Brunton LL, Dillmann WH. Small heat shock proteins and protection against ischemic injury in cardiac myocytes. Circulation 1997; 96:4343-8.
21. Trautinger F, Kokesch C, Herbacek I, Knobler RM, Kindas-Mugge I. Overexpression of the small heat shock protein, hsp27, confers resistance to hyperthermia, but not to oxidative stress and UV-induced cell death, in a stably transfected squamous cell carcinoma cell line. J Photochem Photobiol B 1997; 39:90-5.
22. Thomas JG, Baneyx F. Roles of the Escherichia coli small heat shock proteins IbpA and IbpB in thermal stress management: comparison with ClpA, ClpB, and HtpG In vivo. J Bacteriol 1998; 180:5165-72.
23. Woo J, Iyer S, Cornejo MC, Mori N, Gao L, Sipos I, Maines M, Buelow R. Stress protein-induced immunosuppression: inhibition of cellular immune effector functions following overexpression of haem oxygenase (HSP 32). Transpl Immunol 1998; 6:84-93.
24. Croute F, Beau B, Arrabit C, Gaubin Y, Delmas F, Murat JC, Soleilhavoup JP. Pattern of stress protein expression in human lung cell-line A549 after short- or long-term exposure to cadmium. Environ Health Perspect 2000; 108:55-60.
25. Lambot MA, Peny MO, Fayt I, Haot J, Noel JC. Overexpression of 27-kDa heat shock protein relates to poor histological differentiation in human oesophageal squamous cell carcinoma. Histopathology 2000; 36:326-30.
26. Sanz O, Acarin L, Gonzalez B, Castellano B. Expression of 27 kDa heat shock protein (Hsp27) in immature rat brain after a cortical aspiration lesion. Glia 2001; 36:259-70.
27. Aldrian S, Trautinger F, Frohlich I, Berger W, Micksche M, Kindas-Mugge I. Overexpression of Hsp27 affects the metastatic phenotype of human melanoma cells in vitro. Cell Stress Chaperones 2002; 7:177-85.
28. Yenari MA. Heat shock proteins and neuroprotection. Adv Exp Med Biol 2002; 513:281-99.
29. Wang K, Spector A. ATP causes small heat shock proteins to release denatured protein. Eur J Biochem 2001; 268:6335-45.
30. Haslbeck M. sHsps and their role in the chaperone network. Cell Mol Life Sci 2002; 59:1649-57.
31. Nath D, Rawat U, Anish R, Rao M. Alpha-crystallin and ATP facilitate the in vitro renaturation of xylanase: enhancement of refolding by metal ions. Protein Sci 2002; 11:2727-34.
32. Horwitz J. Alpha-crystallin can function as a molecular chaperone. Proc Natl Acad Sci U S A 1992; 89:10449-53.
33. Kim KK, Kim R, Kim SH. Crystal structure of a small heatshock protein. Nature 1998; 394:595-9.
34. van Montfort RL, Basha E, Friedrich KL, Slingsby C, Vierling E. Crystal structure and assembly of a eukaryotic small heat shock protein. Nat Struct Biol 2001; 8:1025-30.
35. Feil IK, Malfois M, Hendle J, van Der Zandt H, Svergun DI. A novel quaternary structure of the dimeric alpha-crystallin domain with chaperone-like activity. J Biol Chem 2001; 276:12024-9.
36. Eifert C, Burgio MR, Bennett PM, Salerno JC, Koretz JF. N-terminal control of small heat shock protein oligomerization: changes in aggregate size and chaperone-like function. Biochim Biophys Acta 2005; 1748:146-56.
37. Robinson CR, Sauer RT. Optimizing the stability of single-chain proteins by linker length and composition mutagenesis. Proc Natl Acad Sci U S A 1998; 95:5929-34.
38. Farahbakhsh ZT, Huang QL, Ding LL, Altenbach C, Steinhoff HJ, Horwitz J, Hubbell WL. Interaction of alpha-crystallin with spin-labeled peptides. Biochemistry 1995; 34:509-16.
39. Yang C, Koretz JF. The structural and functional role of the region bridging the N-terminal and central core of alpha-crystallin, ARVO Annual Meeting; 2003 May 4-9; Fort Lauderdale (FL).