WAY 405, a new silent 5-HT1A receptor antagonist with low affinity for vascular α1-adrenoceptors

Autonomic and Autacoid Pharmacology

Volumn 25, Issue 4, 2005, Pages 185-189

  Villalobos Molina, R ^a,b   Orozco Mendez M ^a   Lopez Guerrero J J ^a   Gallardo Ortiz I A ^a  

^a DEPARTAMENTO DE FÍSICA   (Mexico)

^b UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO   (Mexico)

Author keywords

5 HT1A receptors; Anaesthetized rat; Hypotension; Vascular 1 adrenoceptors; WAY 405

Indexed keywords

2 DIPROPYLAMINO 8 HYDROXYTETRALIN; ALPHA 1 ADRENERGIC RECEPTOR; ALPHA 1A ADRENERGIC RECEPTOR; ALPHA 1B ADRENERGIC RECEPTOR; ALPHA 1D ADRENERGIC RECEPTOR; N [2 METHYL (4 INDOYL 1 PIPERAZINYL)ETHYL] N (2 PYRIDINYL)CYCLOHEXANE CARBOXAMIDE; NORADRENALIN; SEROTONIN 1A ANTAGONIST; UNCLASSIFIED DRUG; WAY 405;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERY CONSTRICTION; ARTICLE; BLOOD PRESSURE REGULATION; BRADYCARDIA; CARDIOVASCULAR FUNCTION; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; HEART RATE; HYPOTENSION; MALE; NONHUMAN; RAT; RECEPTOR AFFINITY;

8-HYDROXY-2-(DI-N-PROPYLAMINO)TETRALIN; AMINOPYRIDINES; ANIMALS; AORTA; BLOOD PRESSURE; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG INTERACTIONS; HEART RATE; MALE; NOREPINEPHRINE; PIPERAZINES; RABBITS; RATS; RECEPTOR, SEROTONIN, 5-HT1A; RECEPTORS, ADRENERGIC, ALPHA-1; SEROTONIN AGONISTS; SEROTONIN ANTAGONISTS; TAIL; VASOCONSTRICTOR AGENTS;

EID: 26044481968     PISSN: 14748665     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1474-8673.2005.00350.x     Document Type: Article

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