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Volumn 22, Issue 3, 2002, Pages 171-176

Evidence that the hypotensive effect of WAY 100635, a 5-HT1A receptor antagonist, is related to vascular α1-adrenoceptor blockade in the adult rat

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA 1 ADRENERGIC RECEPTOR; N [2 [4 (2 METHOXYPHENYL) 1 PIPERAZINYL]ETHYL] N (2 PYRIDYL)CYCLOHEXANECARBOXAMIDE; PHENYLEPHRINE; SEROTONIN 1A ANTAGONIST;

EID: 0011322283     PISSN: 14748665     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1474-8673.2002.00257.x     Document Type: Article
Times cited : (15)

References (29)
  • 1
    • 0009644628 scopus 로고
    • Some quantitative uses of drug antagonists
    • ARUNLAKSHANA, O. & SCHILD, H.O. (1959). Some quantitative uses of drug antagonists. Br. J. Pharmacol., 14, 48-58.
    • (1959) Br. J. Pharmacol. , vol.14 , pp. 48-58
    • Arunlakshana, O.1    Schild, H.O.2
  • 2
    • 0026499329 scopus 로고
    • Cardiovascular effects of the 5-HT1A receptor ligand, MDL 73005EF, in conscious spontaneously hypertensive rats
    • BUISSON-DEFFERIER, S. & VAN DEN BUUSE, M. (1992). Cardiovascular effects of the 5-HT1A receptor ligand, MDL 73005EF, in conscious spontaneously hypertensive rats. Eur. J. Pharmacol., 223, 133-141.
    • (1992) Eur. J. Pharmacol. , vol.223 , pp. 133-141
    • Buisson-Defferier, S.1    Van Den Buuse, M.2
  • 4
    • 0025145405 scopus 로고
    • Studies on the site and the mechanism of the sympatholytic action of 8-OH-DPAT
    • CLEMENT, M.E. & MCCALL, R.B. (1990). Studies on the site and the mechanism of the sympatholytic action of 8-OH-DPAT. Brain Res., 525, 232-241.
    • (1990) Brain Res. , vol.525 , pp. 232-241
    • Clement, M.E.1    Mccall, R.B.2
  • 6
    • 0025294210 scopus 로고
    • 1A receptor agonists injected into the dorsal raphe nucleus of conscious rats
    • 1A receptor agonists injected into the dorsal raphe nucleus of conscious rats. Eur. J. Pharmacol., 182, 63-72.
    • (1990) Eur. J. Pharmacol. , vol.182 , pp. 63-72
    • Connor, H.E.1    Higgins, G.E.2
  • 11
    • 0030425699 scopus 로고    scopus 로고
    • WAY 100635, a potent and selective 5-hydroxytryptamine 1A antagonist, increases serotonergic neuronal activity in behaving cats: Comparison with (S)-WAY-100135
    • FORNAL, C.A., METZLER, C.W., GALLEGOS, R.A., VEASEY, S.C., MCCREARY, A.C. & JACOBS, B.L. (1996). WAY 100635, a potent and selective 5-hydroxytryptamine 1A antagonist, increases serotonergic neuronal activity in behaving cats: comparison with (S)-WAY-100135. J. Pharmacol. Exp. Ther., 278, 752-762.
    • (1996) J. Pharmacol. Exp. Ther. , vol.278 , pp. 752-762
    • Fornal, C.A.1    Metzler, C.W.2    Gallegos, R.A.3    Veasey, S.C.4    Mccreary, A.C.5    Jacobs, B.L.6
  • 13
    • 0023106392 scopus 로고
    • Cardiovascular response to 8-hydroxy-2-(di-n-propylamino)-tetralin (8-OH-DPAT) in the rat: Site of action and pharmacological analysis
    • FOZARD, J.R., MIR, A.K. & MIDDLEMISS, D.N. (1987). Cardiovascular response to 8-hydroxy-2-(di-n-propylamino)-tetralin (8-OH-DPAT) in the rat: site of action and pharmacological analysis. J. Cardiovasc. Pharmacol., 9, 328-347.
    • (1987) J. Cardiovasc. Pharmacol. , vol.9 , pp. 328-347
    • Fozard, J.R.1    Mir, A.K.2    Middlemiss, D.N.3
  • 14
    • 0000328674 scopus 로고
    • The classification of adrenoceptors (adrenergic receptors). An evaluation from the standpoint of receptor theory
    • Eds. H. Blaschko & E. Muscholl, Springer, Berlin
    • FURCHGOTT, R.F. (1972). The classification of adrenoceptors (adrenergic receptors). An evaluation from the standpoint of receptor theory. In: Catecholaminess, Handbook of Experimental Pharmacology, vol. 33, pp. 283-335, Eds. H. BLASCHKO & E. MUSCHOLL, Springer, Berlin.
    • (1972) Catecholaminess, Handbook of Experimental Pharmacology , vol.33 , pp. 283-335
    • Furchgott, R.F.1
  • 15
    • 0019195506 scopus 로고
    • The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine
    • FURCHGOTT, R.F. & ZAWADSKI, J.V. (1980). The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine. Nature, 288, 373-376.
    • (1980) Nature , vol.288 , pp. 373-376
    • Furchgott, R.F.1    Zawadski, J.V.2
  • 16
    • 0014083047 scopus 로고
    • A method of stimulating the completesympathetic outflow from spinal cord to blood vessel in the pithed rat
    • GILLESPIE, J.S. & MUIR, J.C. (1967). A method of stimulating the completesympathetic outflow from spinal cord to blood vessel in the pithed rat. Br. J. Pharmacol. Chemother., 30, 78-87.
    • (1967) Br. J. Pharmacol. Chemother. , vol.30 , pp. 78-87
    • Gillespie, J.S.1    Muir, J.C.2
  • 17
    • 0021873206 scopus 로고
    • Acute administration of 8-hydroxy-2-(di-n-propyl-amino)-tetralin (8-OH-DPAT), a selective 5-HTreceptor agonist, causes a biphasic blood pressure response and bradycardia in the normotensive SpragueDawley rat and in the spontaneously hypertensive rat
    • GRADIN, K., PETTERSSON, A., HEDNER, T. & PERSSON, B. (1985). Acute administration of 8-hydroxy-2-(di-n-propyl-amino)-tetralin (8-OH-DPAT), a selective 5-HTreceptor agonist, causes a biphasic blood pressure response and bradycardia in the normotensive SpragueDawley rat and in the spontaneously hypertensive rat. J. Neural Transm., 62, 302-319.
    • (1985) J. Neural Transm. , vol.62 , pp. 302-319
    • Gradin, K.1    Pettersson, A.2    Hedner, T.3    Persson, B.4
  • 21
    • 0019215164 scopus 로고
    • Review of the role of the central serotonergic neuronal system in blood pressure regulation
    • KUHN, D.M., WOLF, W.A. & LOVENBERG, W. (1980). Review of the role of the central serotonergic neuronal system in blood pressure regulation. Hypertension, 2, 243-255.
    • (1980) Hypertension , vol.2 , pp. 243-255
    • Kuhn, D.M.1    Wolf, W.A.2    Lovenberg, W.3
  • 23
    • 0021801150 scopus 로고
    • Receptor-binding properties in vitro and in vivo of ritanserin: A very potent and long acting serotonin-S2 antagonist
    • LEYSEN, J.E., GOMMEREN, W., VAN GOMPEL, P., WYNANTS, J., JANSSEN, P.F. & LADURON, P.M. (1985). Receptor-binding properties in vitro and in vivo of ritanserin: a very potent and long acting serotonin-S2 antagonist. Mol. Pharmacol., 27, 600-611.
    • (1985) Mol. Pharmacol. , vol.27 , pp. 600-611
    • Leysen, J.E.1    Gommeren, W.2    Van Gompel, P.3    Wynants, J.4    Janssen, P.F.5    Laduron, P.M.6
  • 24
    • 0021983110 scopus 로고
    • Hypotensive action of 8-hydroxy-2-(di-n-propyl-amino)-tetralin (8-OHDPAT) in spontaneously hypertensive rats
    • MARTIN, G.E. & LIS, E.V. (1985). Hypotensive action of 8-hydroxy-2-(di-n-propyl-amino)-tetralin (8-OHDPAT) in spontaneously hypertensive rats. Arch. Int. Pharmacodyn., 273, 251-261.
    • (1985) Arch. Int. Pharmacodyn. , vol.273 , pp. 251-261
    • Martin, G.E.1    Lis, E.V.2
  • 27
    • 0025273875 scopus 로고
    • Hypotensive effects of 8-hydroxy-2-(di-n-propylamino)tetralin and 5-methylurapidil following stereotaxic microinjection into the ventral medulla of the rat
    • VALENTA, B. & SINGER, E.A. (1990). Hypotensive effects of 8-hydroxy-2-(di-n-propylamino)tetralin and 5-methylurapidil following stereotaxic microinjection into the ventral medulla of the rat. Br. J. Pharmacol., 99, 713-716.
    • (1990) Br. J. Pharmacol. , vol.99 , pp. 713-716
    • Valenta, B.1    Singer, E.A.2
  • 29
    • 0036233445 scopus 로고    scopus 로고
    • Enhanced detection of receptor constitutive activity in the presence of regulators of G protein signaling: Applications to the detection and analysis of inverse agonists and low-efficacy partial agonists
    • WELSBY, P.J., KELLETT, E., WILKINSON, G. & MILLIGAN, G. (2002). Enhanced detection of receptor constitutive activity in the presence of regulators of G protein signaling: applications to the detection and analysis of inverse agonists and low-efficacy partial agonists. Mol. Pharmacol., 61, 1211-1221.
    • (2002) Mol. Pharmacol. , vol.61 , pp. 1211-1221
    • Welsby, P.J.1    Kellett, E.2    Wilkinson, G.3    Milligan, G.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.