Different growth capacity between infant and adult mouse hepatocytes in vitro correlates to the cyclin D1 level without relation to oxidative DNA damage

Liver International

Volumn 25, Issue 5, 2005, Pages 1036-1043

  Imamura, Emi ^a   Yamamoto, Masahiro ^a   Miyakoshi, Masaaki ^a   Honmo, Satoshi ^a   Ozaki, Atsuko ^a   Yoshie, Masumi ^a   Tamakawa, Susumu ^a   Yaginuma, Yuji ^a   Kasai, Shinichi ^a   Ogawa, Katsuhiro ^a  

^a ASAHIKAWA MEDICAL COLLEGE   (Japan)

Author keywords

8 OHdG; Adult; Cyclin D1; Infant; Primary hepatocytes

Indexed keywords

8 HYDROXYDEOXYGUANOSINE; CELL CYCLE PROTEIN; CYCLIN D1; CYCLIN DEPENDENT KINASE 2; CYCLIN DEPENDENT KINASE 4; CYCLIN DEPENDENT KINASE INHIBITOR 1; CYCLIN DEPENDENT KINASE INHIBITOR 1B; CYCLIN E; DNA; EPIDERMAL GROWTH FACTOR; INSULIN; PROTEIN P16INK4A;

APOPTOSIS; ARTICLE; CELL GROWTH; CELL ISOLATION; CELL NUCLEUS; CELL POPULATION; CELL PROLIFERATION; CELL STRUCTURE; CONTROLLED STUDY; CORRELATION FUNCTION; CULTURE MEDIUM; DNA DAMAGE; FEMALE; IN VITRO STUDY; LIVER CELL; MALE; MOUSE; MOUSE STRAIN; NONHUMAN; OXIDATIVE STRESS; PROTEIN EXPRESSION;

EID: 26044460465     PISSN: 14783223     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1478-3231.2005.1125.x     Document Type: Article

References (37)

1. 14 into the DNA of regenerating rat liver. Cancer Res 1964; 24: 509-12.
2. Boylan J M, Anand P, Gruppuso PA. Ribosomal protein S6 phosphorylation and function during late gestation liver development in the rat. J Biol Chem 2001; 276: 44457-63.
3. Sawada N, Ishikawa T. Reduction of potential for replicative but not unscheduled DNA synthesis in hepatocytes isolated from aged as compared to young rats. Cancer Res 1988; 48: 1618-22.
4. Friedmann T, Xu L, Wolff J, Yee J K, Miyanohara A. Retrovirus vector-mediated gene transfer into hepatocytes. Mol Biol Med 1989; 6: 117-25.
5. Koch K S, Brownlee G G, Goss S J, Martinez-conde A, Leffert H L. Retroviral vector infection and transplantation in rats of primary fetal rat hepatocytes. J Cell Sci 1991; 99(part 1): 121-30.
6. Inagaki M, Ogawa K. High sensitivity of neonatal rat hepatocytes to retroviral-mediated gene transfer and their transplantation into the spleen of adult rat. Cell Struct Funct 1991; 16: 283-8.
7. Xu L, Gao C, Sands M S, Cai S R, Nichols T C, Bellinger D A, Raymer R A, McCorquodale S, Ponder K P. Neonatal or hepatocyte growth factor-potentiated adult gene therapy with a retroviral vector results in therapeutic levels of canine factor IX for hemophilia B. Blood 2003; 101: 3924-32.
8. Cusick R A, Lee H, Sano K, Pollok J M, Utsunomiya H, Ma P X, Langer R, Vacanti J P. The effect of donor and recipient age on engraftment of tissue-engineered liver. J Pediatr Surg 1997; 32: 357-60.
9. Vesselinovitch S D, Rao Kv, Mihailovich N. Neoplastic response of mouse tissues during perinatal age periods and its significance in chemical carcinogenesis. Natl Cancer Inst Monogr 1979; 239-50.
10. Loyer P, Cariou S, Glaise D, Bilodeau M, Baffet G, Guguen-Guillouzo C. Growth factor dependence of progression through G1 and S phases of adult rat hepatocytes in vitro. Evidence of a mitogen restriction point in mid-late G1. J Biol Chem 1996; 271: 11484-92.
11. Thaler F J, Michalopoulos G K. Hepatopoietin A: partial characterization and trypsin activation of a hepatocyte growth factor. Cancer Res 1985; 45: 2545-9.
12. Nakamura T, Nishizawa T, Hagiya M, Seki T, Shimonishi M, Sugimura A, Tashiro K, Shimizu S. Molecular cloning and expression of human hepatocyte growth factor. Nature 1989; 342: 440-3.
13. Mead J E, Fausto N. Transforming growth factor α may be a physiological regulator of liver regeneration by means of an autocrine mechanism. Proc Natl Acad Sci USA 1989; 86: 1558-62.
14. 1 phase progression in proliferating hepatocytes. Mol Cell Biol 1999; 19: 6003-11.
15. Rescan C, Coutant A, Talarmin H, Theret N, Glaise D, Guguen-Guillouzo C, Baffet G. Mechanism in the sequential control of cell morphology and S phase entry by epidermal growth factor involves distinct MEK/ERK activations. Mol Biol Cell 2001; 12: 725-38.
16. Auer K L, Contessa J, Brenz-Verca S, Pirola L, Rusconi S, Cooper G, Abo A, Wymann M P, Davis R J, Birrer M, Dent P. The Ras/Racl/Cdc42/Sek/Jnk/c-Jun cascade is a key pathway by which agonists stimulate DNA synthesis in primary cultures of rat hepatocytes. Mol Biol Cell 1998; 9: 561-73.
17. Albrecht J H, Hansen L K. Cyclin D1 promotes mitogen-independent cell cycle progression in hepatocytes. Cell Growth Differ 1999; 10: 397-404.
18. Nelsen C J, Rickheim D G, Timchenko N A, Stanley M W, Albrecht J H. Transient expression of cyclin D1 is sufficient to promote hepatocyte replication and liver growth in vivo. Cancer Res 2001; 61: 8564-8.
19. Ink4a-null mice. Biochem J 1998; 336(part 3): 551-60.
20. Kip1 enhances the transplantation efficiency of hepatocytes transferred into diseased livers. J Clin Invest 2001; 108: 383-90.
21. Tang D G, Tokumoto Y M, Apperly J A, Lloyd A C, Raff M C. Lack of replicative senescence in cultured rat oligodendrocyte precursor cells. Science 2001; 291: 868-71.
22. Mathon N F, Malcolm D S, Harrisingh M C, Cheng L, Lloyd A C. Lack of replicative senescence in normal rodent glia. Science 2001; 291: 872-5.
23. Hart R W, Setlow R B. Correlation between deoxyribonucleic acid excision-repair and life-span in a number of mammalian species. Proc Natl Acad Sci Usa 1974; 71: 2169-73.
24. Kapahi P, Boulton M E, Kirkwood T B. Positive correlation between mammalian life span and cellular resistance to stress. Free Radic Biol Med 1999; 26: 495-500.
25. Ferraris M, Radice S, Catalani P, Francolini M, Marabini L, Chiesara E. Early oxidative damage in primary cultured trout hepatocytes: a time course study. Aquat Toxicol 2002; 59: 283-96.
26. Caraceni P, De Maria N, Ryu H S, Colantoni A, Roberts L, Maidt M L, Pye Q, Bernardi M, Van Thiel D H, Floyd R A. Proteins but not nucleic acids are molecular targets for the free radical attack during re-oxygenation of rat hepatocytes. Free Radic Biol Med 1997; 23: 339-44.
27. Hagen T M, Yowe D L, Bartholomew J C, Wehr C M, Do K L, Park J Y, Ames B N. Mitochondrial decay in hepatocytes from old rats: membrane potential declines, heterogeneity and oxidants increase. Proc Natl Acad Sci USA 1997; 94: 3064-9.
28. Waf1/Cip1, cyclin D1 and Ogg1. Carcinogenesis 2002; 23: 341-9.
29. Mosmann T. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J Immunol Methods 1983; 65: 55-63.
30. Roovers K, Assoian R K. Integrating the Map kinase signal into the G1 phase cell cycle machinery. Bioessays 2000; 22: 818-26.
31. Brewer J W, Hendershot L M, Sherr C J, Diehl J A. Mammalian unfolded protein response inhibits cyclin D1 translation and cell-cycle progression. Proc Natl Acad Sci USA 1999; 96: 8505-10.
32. Diehl J A, Cheng M, Roussel M F, Sherr C J. Glycogen synthase kinase-3β regulates cyclin D1 proteolysis and subcellular localization. Genes Dev 1998; 12: 3499-511.
33. Kip1 CDK 'inhibitors' are essential activators of cyclin D-dependent kinases in murine fibroblasts. Embo J 1999; 18: 1571-83.
34. Iakova P, Awad S S, Timchenko N A. Aging reduces proliferative capacities of liver by switching pathways of C/EBPα growth arrest. Cell 2003; 113: 495-506.
35. Wang X, Kiyokawa H, Dennewitz M B, Costa R H. The Forkhead Box m1b transcription factor is essential for hepatocyte DNA replication and mitosis during mouse liver regeneration. Proc Natl Acad Sci USA 2002; 99: 16881-6.
36. Trautwein C, Will M, Kubicka S, Rakemann T, Flemming P, Manns M P. 2-acetaminofluorene blocks cell cycle progression after hepatectomy by p21 induction and lack of cyclin E expression. Oncogene 1999; 18: 6443-53.
37. Lindeman B, Skarpen E, Oksvold M P, Huitfeldt H S. The carcinogen 2-acetylaminofluorene inhibits activation and nuclear accumulation of cyclin-dependent kinase 2 in growth-induced rat liver. Mol Carcinogen 2000; 27: 190-9.