Pyrazolopyridinones as functionally selective GABAA ligands

Bioorganic and Medicinal Chemistry Letters

Volumn 15, Issue 22, 2005, Pages 4998-5002

  Blackaby, Wesley P ^a   Atack, John R ^a   Bromidge, Frances ^a   Lewis, Richard ^a   Russell, Michael G N ^a   Smith, Alison ^a   Wafford, Keith ^a   McKernan, Ruth M ^a   Street, Leslie J ^a   Castro, José L ^a  

^a NEUROSCIENCE RESEARCH CENTRE   (United Kingdom)

Author keywords

GABAA; Pyrazolopyridinones

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR; 4 AMINOBUTYRIC ACID RECEPTOR BLOCKING AGENT; 4 AMINOBUTYRIC ACID RECEPTOR STIMULATING AGENT; BENZODIAZEPINE; CHLORDIAZEPOXIDE; LIGAND; PYRAZOLONE DERIVATIVE; PYRIDONE DERIVATIVE;

ANIMAL EXPERIMENT; ARTICLE; BINDING AFFINITY; BINDING SITE; CONTROLLED STUDY; DRUG POTENCY; DRUG RECEPTOR BINDING; DRUG SELECTIVITY; MOUSE; NONHUMAN; RECEPTOR OCCUPANCY; STRUCTURE ACTIVITY RELATION;

AZO COMPOUNDS; LIGANDS; MOLECULAR STRUCTURE; PYRIDINES; RECEPTORS, GABA-A; SENSITIVITY AND SPECIFICITY; STRUCTURE-ACTIVITY RELATIONSHIP; SUBSTRATE SPECIFICITY;

EID: 25844507464     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2005.08.006     Document Type: Article

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