Differential activation of LFA-1 and Mac-1 ligand binding domains

Biochemical and Biophysical Research Communications

Volumn 337, Issue 1, 2005, Pages 142-148

  Walters, Susannah E ^a   Tang, Ren Hong ^b   Cheng, Ming ^b   Tan, Suet Mien ^b   Law, S K Alex ^a,b  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b NANYANG TECHNOLOGICAL UNIVERSITY   (Singapore)

Author keywords

Activation; I domain; Integrin

Indexed keywords

CD11B ANTIGEN; ISOLEUCINE; LYMPHOCYTE FUNCTION ASSOCIATED ANTIGEN 1;

ARTICLE; CELL ADHESION; CONTROLLED STUDY; EMBRYO; GENE CONTROL; GENE MUTATION; HUMAN; HUMAN CELL; LIGAND BINDING; OBSERVATION; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN DOMAIN;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANTIGENS, CD11; ANTIGENS, CD11A; ANTIGENS, CD11B; CELL ADHESION; CELL LINE; HUMANS; INTERCELLULAR ADHESION MOLECULE-1; K562 CELLS; LIGANDS; LYMPHOCYTE FUNCTION-ASSOCIATED ANTIGEN-1; MACROPHAGE-1 ANTIGEN; MOLECULAR SEQUENCE DATA; MUTATION; SEQUENCE ALIGNMENT;

EID: 25844477076     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbrc.2005.08.269     Document Type: Article

References (32)

1. R.O. Hynes Integrins: bidirectional, allosteric signaling machines Cell 110 2002 673 687
2. F. Sanchez-Madrid, J.A. Nagy, E. Robbins, P. Simon, and T.A. Springer A human leukocyte differentiation antigen family with distinct α-subunits and a common β-subunit: the lymphocyte function-associated antigen (LFA-1), the C3bi complement receptor (OKM1/Mac-1), and the p150,95 molecule J. Exp. Med. 158 1983 1785 1803
3. M. van der Vieren, H. le Trong, C.L. Wood, P.F. Moore, T. St John, D. Staunton, and W.M. Gallatin A novel leukointegrin, αdβ2, binds preferentially to ICAM-3 Immunity 3 1995 683 690
4. J.P. Xiong, T. Stehle, B. Diefenbach, R. Zhang, R. Dunker, D.L. Scott, A. Joachimiak, S.L. Goodman, and M.A. Arnaout Crystal structure of the extracellular segment of integrin αVβ3 Science 294 2001 339 345
5. E.F. Plow, T.A. Haas, L. Zhang, J. Loftus, and J.W. Smith Ligand binding to integrins J. Biol. Chem. 275 2000 21785 21788
6. A. Qu, and D.J. Leahy Crystal structure of the I-domain from the CD11a/CD18 (LFA-1, αLβ2) integrin Proc. Natl. Acad. Sci. USA 92 1995 10277 10281
7. J.O. Lee, P. Rieu, M.A. Arnaout, and R. Liddington Crystal structure of the A domain from the α subunit of integrin CR3 (CD11b/CD18) Cell 80 1995 631 638
8. J.O. Lee, L.A. Bankston, M.A. Arnaout, and R.C. Liddington Two conformations of the integrin A-domain (I-domain): a pathway for activation? Structure 3 1995 1333 1340
9. T. Vorup-Jensen, C. Ostermeier, M. Shimaoka, U. Hommel, and T.A. Springer Structure and allosteric regulation of the αXβ2 integrin I domain Proc. Natl. Acad. Sci. USA 100 2003 1873 1878
10. J.R. Huth, E.T. Olejniczak, R. Mendoza, H. Liang, E.A. Harris, M.L. Lupher Jr., A.E. Wilson, S.W. Fesik, and D.E. Staunton NMR and mutagenesis evidence for an I domain allosteric site that regulates lymphocyte function-associated antigen 1 ligand binding Proc. Natl. Acad. Sci. USA 97 2000 5231 5236
11. J.P. Xiong, R. Li, M. Essafi, T. Stehle, and M.A. Arnaout An isoleucine-based allosteric switch controls affinity and shape shifting in integrin CD11b A-domain J. Biol. Chem. 275 2000 38762 38767
12. S.M. Tan, R.H. Hyland, A. Al-Shamkhani, W.A. Douglass, J.M. Shaw, and S.K.A. Law Effect of integrin β2 subunit truncations on LFA-1 (CD11a/CD18) and Mac-1 (CD11b/CD18) assembly, surface expression, and function J. Immunol. 165 2000 2574 2581
13. W. Yang, M. Shimaoka, A. Salas, J. Takagi, and T.A. Springer Intersubunit signal transmission in integrins by a receptor-like interaction with a pull spring Proc. Natl. Acad. Sci. USA 101 2004 2906 2911
14. J.P. Xiong, T. Stehle, S.L. Goodman, and M.A. Arnaout New insights into the structural basis of integrin activation Blood 102 2003 1155 1159
15. J.E.K. Hildreth, F.M. Gotch, P.D.K. Hildreth, and A.J. McMichael A human lymphocyte-associated antigen involved in cell-mediated lympholysis Eur J. Immunol. 13 1983 202 208
16. P. Uciechowski, and R. von Schmidt Cluster report: CD11 W.D. Knapp B. Dorken W.R. Gilks E.P. Rieber R.E. Schmidt H. Stein A.E.G.Kr. von dem Borne Leucocyte typing IV: white cell differentiation antigens 1989 Oxford University Press Oxford 534 551
17. E.C. Mathew, J.M. Shaw, F.A. Bonilla, S.K.A. Law, and D.A. Wright A novel point mutation in CD18 causing the expression of dysfunctional CD11/CD18 leucocyte integrins in a patient with leucocyte adhesion deficiency (LAD) Clin. Exp. Immunol. 121 2000 133 138
18. S.D. Wright, P.E. Rao, W.C. van Voorhis, L.S. Craigmyle, K. Iida, M.A. Talle, E.F. Westberg, G. Goldstein, and S.C. Silverstein Identification of the C3bi receptor of human monocytes and macrophages by using monoclonal antibodies Proc. Natl. Acad. Sci. USA 80 1983 5699 5703
19. D. Andrew, A. Shock, E. Ball, S. Ortlepp, J. Bell, and M. Robinson KIM185, a monoclonal antibody to CD18 which induces a change in the conformation of CD18 and promotes both LFA-1- and CR3-dependent adhesion Eur. J. Immunol. 23 1993 2217 2222
20. V. Bazil, I. Stefanova, I. Hilgert, H. Kristofova, S. Vanek, and V. Horejsi Monoclonal antibodies against human leucocyte antigens. IV. Antibodies against subunits of the LFA-1 (CD11a/CD18) leucocyte-adhesion glycoprotein Folia Biol. (Praha) 36 1990 41 50
21. D.L. Simmons Cloning cell surface molecules by transient expression in mammalian cells D. Hartley Cellular Interactions in Development: A Practical Approach 1993 IRL Press Oxford 93 128
22. W.A. Douglass, R.H. Hyland, C.D. Buckley, A. AlShamkhani, J.M. Shaw, S.L. Scarth, D.L. Simmons, and S.K.A. Law The role of the cysteine-rich region of the β2 integrin subunit in the leukocyte function-associated antigen-1 (LFA-1, αLβ2, CD11a/CD18) heterodimer formation and ligand binding FEBS Lett. 440 1998 414 418
23. R.B. DuBridge, P. Tang, H.C. Hsia, P.M. Leong, J.H. Miller, and M.P. Calos Analysis of mutation in human cells by using an Epstein-Barr virus shuttle system Mol. Cell. Biol. 7 1987 379 387
24. S.S. Heinzel, P.J. Krysan, M.P. Calos, and R.B. DuBridge Use of simian virus 40 replication to amplify Epstein-Barr virus shuttle vectors in human cells J. Virol. 62 1998 3738 3746
25. G.E. Davis The Mac-1 and p150,95 β-2 integrins bind denatured proteins to mediate leukocyte cell substrate adhesion Exp. Cell Res. 200 1992 242 252
26. S.D. Marlin, and T.A. Springer Purified intercellular adhesion molecule-1 (ICAM-1) is a ligand for lymphocyte function-associated antigen 1 (LFA-1) Cell 51 1987 813 819
27. M. Shimaoka, J. Takagi, and T.A. Springer Conformational regulation of integrin structure and function Annu. Rev. Biophys. Biomol. Struct. 31 2002 485 516
28. J. Emsley, S.L. King, J.M. Bergelson, and R.C. Liddington Crystal structure of the I domain from integrin α2β1 J. Biol. Chem. 272 1997 28512 28517
29. M. Shimaoka, T. Xiao, J.H. Liu, Y. Yang, Y. Dong, C.D. Jun, A. McCormack, R. Zhang, A. Joachimiak, J. Takagi, J.H. Wang, and T.A. Springer Structures of the αL I domain and its complex with ICAM-1 reveal a shape-shifting pathway for integrin regulation Cell 112 2003 99 111
30. M. Shimaoka, C. Lu, R.T. Palframan, U.H. von Andrian, A. McCormack, J. Takagi, and T.A. Springer Reversibly locking a protein fold in an active conformation with a disulfide bond: integrin αL I domains with high affinity and antagonist activity in vivo Proc. Natl. Acad. Sci. USA 98 2001 6009 6014
31. C. Lu, M. Shimaoka, M. Ferzly, C. Oxvig, J. Takagi, and T.A. Springer An isolated, surface-expressed I domain of the integrin αLβ2 is sufficient for strong adhesive function when locked in the open conformation with a disulfide bond Proc. Natl. Acad. Sci. USA 98 2001 2387 2392
32. D.G. Higgins, J.D. Thompson, and T.J. Gibson ClustalW: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice Nucleic Acid Res. 22 1994 4673 4680