Inhibitors of protein:farnesyl transferase and protein:geranylgeranyl transferase I: Synthesis of homologous diphosphonate analogs of isoprenylated pyrophosphate

Bioorganic Chemistry

Volumn 26, Issue 5, 1998, Pages 269-282

  Overhand, Mark ^a   Stuivenberg, Hanneke R ^a   Pieterman, Elsbet ^b   Cohen, Louis H ^b   Van Leeuwen, Rick E W ^b   Valentijn, A Rob P M ^a   Overkleeft, Herman S ^a   Van Der Marel, Gijs A ^a   Van Boom, Jacques H ^a  

^a LEIDEN UNIVERSITY   (Netherlands)

^b TNO   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

BISPHOSPHONIC ACID DERIVATIVE; ENZYME INHIBITOR; GERANYLTRANSFERASE; PROTEIN FARNESYLTRANSFERASE;

ARTICLE; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME SPECIFICITY; PHOSPHATE METABOLISM; PRIORITY JOURNAL;

EID: 0032406503     PISSN: 00452068     EISSN: None     Source Type: Journal    
DOI: 10.1006/bioo.1998.1101     Document Type: Article

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