Design, synthesis, and bioavailability evaluation of coumarin-based prodrug of meptazinol

Bioorganic and Medicinal Chemistry Letters

Volumn 15, Issue 22, 2005, Pages 4953-4956

  Xie, Qiong ^a   Wang, Xiaolin ^a   Wang, Xinghai ^a   Jiang, Zhiqiang ^a   Qiu, Zhuibai ^a  

^a FUDAN UNIVERSITY   (China)

Author keywords

Bioavailability; Coumarin based prodrug; Meptazinol; Synthesis

Indexed keywords

3 [2 (PROPIONYLOXY)PHENYL] 2 PROPENOIC MEPTAZINOL ESTER; COUMARIN DERIVATIVE; MEPTAZINOL; PRODRUG; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG DESIGN; DRUG SCREENING; DRUG SYNTHESIS; FIRST PASS EFFECT; NONHUMAN; RAT;

ANIMALS; BIOLOGICAL AVAILABILITY; COUMARINS; DRUG DESIGN; MEPTAZINOL; MOLECULAR STRUCTURE; PRODRUGS; RATS;

EID: 25844442354     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2005.08.016     Document Type: Article

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